ATE544457T1 - Verfahren zur behandlung bzw. prävention systemischer entzündungen - Google Patents

Verfahren zur behandlung bzw. prävention systemischer entzündungen

Info

Publication number
ATE544457T1
ATE544457T1 AT08730501T AT08730501T ATE544457T1 AT E544457 T1 ATE544457 T1 AT E544457T1 AT 08730501 T AT08730501 T AT 08730501T AT 08730501 T AT08730501 T AT 08730501T AT E544457 T1 ATE544457 T1 AT E544457T1
Authority
AT
Austria
Prior art keywords
prevention
procedure
treatment
systemic inflammation
infant
Prior art date
Application number
AT08730501T
Other languages
English (en)
Inventor
Robert Mcmahon
William Michael Russell
Udo Herz
Josef Neu
Original Assignee
Mead Johnson Nutrition Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39469924&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE544457(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mead Johnson Nutrition Co filed Critical Mead Johnson Nutrition Co
Application granted granted Critical
Publication of ATE544457T1 publication Critical patent/ATE544457T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT08730501T 2007-02-28 2008-02-22 Verfahren zur behandlung bzw. prävention systemischer entzündungen ATE544457T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90412207P 2007-02-28 2007-02-28
PCT/US2008/054710 WO2008106372A1 (en) 2007-02-28 2008-02-22 Method for treating or preventing systemic inflammation

Publications (1)

Publication Number Publication Date
ATE544457T1 true ATE544457T1 (de) 2012-02-15

Family

ID=39469924

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08730501T ATE544457T1 (de) 2007-02-28 2008-02-22 Verfahren zur behandlung bzw. prävention systemischer entzündungen

Country Status (14)

Country Link
US (2) US9408819B2 (de)
EP (2) EP2114423B2 (de)
CN (3) CN101678053B (de)
AT (1) ATE544457T1 (de)
BR (2) BRPI0808145A2 (de)
CA (2) CA2676956C (de)
ES (2) ES2381232T3 (de)
HK (2) HK1136969A1 (de)
MX (2) MX2009008875A (de)
MY (2) MY151892A (de)
PL (2) PL2114423T3 (de)
RU (2) RU2468808C2 (de)
TW (2) TWI418355B (de)
WO (2) WO2008106373A1 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767203B2 (en) 1998-08-07 2010-08-03 Ganeden Biotech, Inc. Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption
MX2009008875A (es) * 2007-02-28 2009-08-28 Mead Johnson Nutrition Co Producto que contiene probiotico inactivado para niños o infantes.
US9113641B2 (en) * 2007-12-06 2015-08-25 Arla Foods Amba Probiotic bacteria and regulation of fat storage
RU2642301C9 (ru) * 2008-11-03 2018-06-27 Нестек С.А. Пробиотический бактериальный штамм для получения питательной композиции, улучшающей характер сна
ES2639364T3 (es) * 2009-04-29 2017-10-26 Ganeden Biotech, Inc. Formulación de membrana celular bacteriana
EP2251020A1 (de) * 2009-05-11 2010-11-17 Nestec S.A. Kurzzeitige Hochtemperaturbehandlung erzeugt mikrobielle Zubereitungen mit entzündungshemmenden Profilen
CA2761444C (en) * 2009-05-11 2018-04-24 Nestec S.A. Lactobacillus johnsonii la1 ncc533 (cncm i-1225) and immune disorders
EP2251022A1 (de) * 2009-05-11 2010-11-17 Nestec S.A. Nicht-replizierte Mikroorganismen und deren immunstärkender Effekt
BR112012017978A2 (pt) * 2010-01-19 2016-05-03 Abbott Lab fórmulas nutricionais contendo simbióticos
WO2011130487A1 (en) 2010-04-14 2011-10-20 Ganeden Biotech, Inc. Probiotic confection and lipid compositions
EP2455094A1 (de) * 2010-11-11 2012-05-23 Nestec S.A. Nicht replizierende probiotische Mikroorganismen als Schutz vor Magen-Darm-Infektionen bei Kindern
AU2011328073A1 (en) * 2010-11-11 2013-05-02 Nestec S.A. Frozen confections containing probiotic micro-organisms
EP2455092A1 (de) * 2010-11-11 2012-05-23 Nestec S.A. Nicht replizierende probiotische Mikroorganismen als Schutz vor Infektionen der oberen Atemwege
EP2452576A1 (de) * 2010-11-11 2012-05-16 Nestec S.A. Extrudierte nicht-replizierende probiotische Mikroorganismen und ihre positiven Auswirkungen auf die Gesundheit
EP2455093A1 (de) * 2010-11-11 2012-05-23 Nestec S.A. Nicht replizierende probiotische Bakterien und Prävention bzw. Behandlung von Infektionen bei Kindern
WO2012135499A1 (en) 2011-03-31 2012-10-04 Ganeden Biotech, Inc. Probiotic sports nutrition compositions
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
KR101166798B1 (ko) * 2011-12-19 2012-07-26 김대현 락토바실러스 애시도필러스 엘비의 사균을 포함하는 알레르기 질환의 치료 또는 예방용 의약 조성물
US9545415B2 (en) * 2012-01-06 2017-01-17 Skyview Enterprise Ltd. Anti-inflammatory compounds in combination with hydrogen for the treatment of inflammation
US20130251829A1 (en) * 2012-03-23 2013-09-26 Mead Johnson Nutrition Company Probiotic derived non-viable material for infection prevention and treatment
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
JP6643988B2 (ja) * 2013-08-09 2020-02-12 エービー−バイオティクス，エセ．ア． 乳児の過剰な泣きのためのプロバイオティクス
US20160303226A1 (en) * 2013-11-25 2016-10-20 Nestec S.A. Heat-treated formulation of bifidobacterium lactis ncc 2818 reduces allergic manifestations
RU2687038C1 (ru) * 2013-11-29 2019-05-06 Нестек С.А. Соответствующие возрастным потребностям питательные композиции с различным содержанием белка
WO2016102951A1 (en) 2014-12-23 2016-06-30 4D Pharma Research Limited Pirin polypeptide and immune modulation
ME02997B (de) 2014-12-23 2018-10-20 4D Pharma Res Ltd Ein bacteroides thetaiotaomicron stamm und seine verwendung zur verminderung von entzündungen
PL3206700T3 (pl) 2015-06-15 2019-11-29 4D Pharma Res Ltd Kompozycje zawierające szczepy bakteryjne
MD3307288T2 (ro) 2015-06-15 2019-12-31 4D Pharma Res Ltd Compoziții care conțin tulpini bacteriene
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
CN115364122A (zh) 2015-06-15 2022-11-22 4D制药研究有限公司 包含细菌菌株的组合物
EA034677B1 (ru) 2015-11-20 2020-03-05 4Д Фарма Рисёрч Лимитед Композиции для лечения или профилактики рака, содержащие штамм enterococcus gallinarum
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
DK3313423T3 (da) 2016-03-04 2019-05-20 4D Pharma Plc Sammensætninger omfattende bakterielle blautia-stammer til behandling af visceral hypersensitivitet
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
ES2657665B1 (es) * 2016-09-05 2018-12-17 Pedro Jose DE LA FUENTE BLASCO Productos para la salud con probióticos inactivados y uso de dichos productos
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
CN107115362A (zh) * 2017-04-28 2017-09-01 青岛东海药业有限公司 凝结芽孢杆菌在制备预防或治疗支气管哮喘制剂中的应用
LT3630136T (lt) 2017-05-22 2021-06-10 4D Pharma Research Limited Kompozicijos, apimančios bakterines padermes
WO2018215782A1 (en) 2017-05-24 2018-11-29 4D Pharma Research Limited Compositions comprising bacterial strain
HUE052258T2 (hu) 2017-06-14 2021-04-28 4D Pharma Res Ltd Megasphaera nemzetségbe tartozó baktériumtörzset tartalmazó készítmény, és alkalmazása
IL283973B (en) 2017-06-14 2022-08-01 4D Pharma Res Ltd Preparations containing bacterial strains
EP3638271B1 (de) 2017-06-14 2020-10-14 4D Pharma Research Limited Zusammensetzungen mit bakterienstämmen
CN108041607A (zh) * 2017-12-26 2018-05-18 广州普正生物科技有限公司 一种护齿益生菌咀嚼软胶囊
RU2770463C1 (ru) * 2020-10-14 2022-04-18 федеральное государственное бюджетное образовательное учреждение высшего образования "Алтайский государственный технический университет им. И.И. Ползунова" (АлтГТУ) Способ производства мягкого сыра
TWI802009B (zh) * 2021-09-16 2023-05-11 創百股份有限公司 使用熱致死的乳酸菌菌株來治療和/或預防微粒物質-誘發的肺損傷

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804179A (en) * 1985-12-31 1998-09-08 Research Corporation Technologies, Inc. Lactobacillus compositions and methods for treating urinary tract infections
RU2031586C1 (ru) * 1993-02-05 1995-03-27 Тамара Георгиевна Извекова Биологически активный кисломолочный продукт "ацидолакт-наринэ" и способ его получения
US6156320A (en) * 1993-02-05 2000-12-05 Harry Parsekian Fermented milk nutraceuticals
US6180100B1 (en) * 1994-09-30 2001-01-30 Urex Biotech., Inc. Lactobacillus compositions and methods for treating urinary tract infections
FI104465B (fi) * 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
ATE253640T1 (de) * 1998-06-17 2003-11-15 Nestle Sa Mobile genetische elemente als werkzeuge zur genetischen modifikation von l. delbrueckii oder l. helveticus
US6399055B1 (en) * 1998-10-27 2002-06-04 Compagnie Gervais Danone Method and composition for treatment of infant diarrhea
WO2000035465A2 (en) * 1998-12-11 2000-06-22 Urex Biotech Inc. Oral administration of lactobacillus for the treatment and prevention of urogenital infection
ID29150A (id) * 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
AU2001233529A1 (en) * 2000-02-10 2001-08-20 Andrew W. Bruce Probiotic therapy for newborns
BR0116349A (pt) * 2000-12-18 2003-12-23 Probiohealth Llc Compostos probióticos derivados da cepa ke01 de lactobacillus casei
KR100419132B1 (ko) * 2000-12-29 2004-02-18 조성근 위·장 점막 부착성과 증식성, 내산성, 내담즙성 및헬리코박터 파일로리, 대장균 0157:ｈ7에 대한 항균성이우수한 락토바실러스 파라카제이 서브스패시즈 파라카제이ｃｓｋ 01
FI109602B (fi) * 2001-01-25 2002-09-13 Valio Oy Probioottiyhdistelmä
KR100845456B1 (ko) * 2001-02-06 2008-07-10 소시에떼 데 프로듀이 네슬레 소시에떼아노님 젖산균 및 비피도균에 의한 내독소 결합
PE20030283A1 (es) * 2001-07-26 2003-05-01 Alimentary Health Ltd Cepas de lactobacillus casei
PE20030274A1 (es) * 2001-07-26 2003-05-08 Alimentary Health Ltd Cepas de lactobacillus salivarius
US20030092163A1 (en) * 2001-07-26 2003-05-15 Collins John Kevin Probiotic bifidobacterium strains
EP1364586A1 (de) 2002-05-24 2003-11-26 Nestec S.A. Probiotika und Oraltoleranz
US20050100531A1 (en) * 2002-06-13 2005-05-12 John Bienenstock Probiotic therapies
WO2004003235A2 (en) * 2002-06-28 2004-01-08 Puleva Biotech, S.A. Probiotic strains, a process for the selection of them, compositions thereof, and their use
WO2004069156A2 (en) 2003-01-30 2004-08-19 The Regents Of The University Of California Inactivated probiotic bacteria and methods of use thereof
US20040208863A1 (en) * 2003-01-30 2004-10-21 James Versalovic Anti-inflammatory activity from lactic acid bacteria
WO2004087178A1 (en) * 2003-03-31 2004-10-14 Alimentary Health Limited A formulation comprising a bacterial strain
NZ544642A (en) * 2003-06-23 2009-01-31 Nestec Sa Infant or follow-on formula
US7125963B2 (en) * 2004-03-03 2006-10-24 En N Tech Inc Treatments for contaminant reduction in lactoferrin preparations and lactoferrin containing compositions
US20080255252A1 (en) * 2004-03-15 2008-10-16 Tissugen Pty. Ltd. Infectious Aetiology of Prostatic Disease and Methods to Identify Causative Agents
JP2008535861A (ja) * 2005-04-08 2008-09-04 ザ プロクター アンド ギャンブル カンパニー ヒトの美しさの利益のための経口投与されたプロバイオティクビフィズス菌の使用方法
CA2604338A1 (en) * 2005-04-13 2006-10-19 Nestec S.A. Infant formula with probiotics
US20060233762A1 (en) 2005-04-15 2006-10-19 Mcmahon Robert J Method for treating or preventing systemic inflammation in formula-fed infants
US20060233752A1 (en) * 2005-04-15 2006-10-19 Mcmahon Robert J Method for treating or preventing systemic inflammation in formula-fed infants
WO2006124630A2 (en) * 2005-05-13 2006-11-23 New England Medical Center Hospitals, Inc. Compositions and methods for enhancing the efficacy of vaccines
MX2009008875A (es) * 2007-02-28 2009-08-28 Mead Johnson Nutrition Co Producto que contiene probiotico inactivado para niños o infantes.

Also Published As

Publication number Publication date
MY145769A (en) 2012-04-13
TW200906426A (en) 2009-02-16
TWI494114B (zh) 2015-08-01
RU2468807C2 (ru) 2012-12-10
ES2388198T5 (es) 2020-07-14
BRPI0808052A2 (pt) 2014-06-24
MX2009009119A (es) 2009-09-04
CA2679374A1 (en) 2008-09-04
US20080206212A1 (en) 2008-08-28
CN101636172A (zh) 2010-01-27
PL2114423T3 (pl) 2012-10-31
RU2009135873A (ru) 2011-04-10
US20080206213A1 (en) 2008-08-28
CN101678053B (zh) 2015-12-16
ES2388198T3 (es) 2012-10-10
CN101678053A (zh) 2010-03-24
ES2381232T3 (es) 2012-05-24
WO2008106373A1 (en) 2008-09-04
CA2676956C (en) 2017-06-13
MX2009008875A (es) 2009-08-28
RU2009135871A (ru) 2011-04-10
HK1141729A1 (zh) 2010-11-19
CA2679374C (en) 2016-05-31
EP2124977B1 (de) 2012-02-08
EP2124977B9 (de) 2012-05-02
CA2676956A1 (en) 2008-09-04
US9408818B2 (en) 2016-08-09
WO2008106372A1 (en) 2008-09-04
EP2114423A1 (de) 2009-11-11
HK1136969A1 (en) 2010-07-16
EP2114423B2 (de) 2020-01-01
TW200900075A (en) 2009-01-01
PL2124977T3 (pl) 2012-07-31
EP2124977A1 (de) 2009-12-02
CN105796607A (zh) 2016-07-27
BRPI0808145A2 (pt) 2021-03-23
TWI418355B (zh) 2013-12-11
EP2114423B1 (de) 2012-06-06
US9408819B2 (en) 2016-08-09
MY151892A (en) 2014-07-14
RU2468808C2 (ru) 2012-12-10

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