ATE538809T1 - Verfahren zur auswahl von geeigneten patienten für den wt1-impfstoff - Google Patents
Verfahren zur auswahl von geeigneten patienten für den wt1-impfstoffInfo
- Publication number
- ATE538809T1 ATE538809T1 AT04746847T AT04746847T ATE538809T1 AT E538809 T1 ATE538809 T1 AT E538809T1 AT 04746847 T AT04746847 T AT 04746847T AT 04746847 T AT04746847 T AT 04746847T AT E538809 T1 ATE538809 T1 AT E538809T1
- Authority
- AT
- Austria
- Prior art keywords
- vaccine
- selecting appropriate
- biological sample
- precursor cells
- highly responsive
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 239000012472 biological sample Substances 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000004043 responsiveness Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003184436 | 2003-06-27 | ||
| JP2004070497 | 2004-03-12 | ||
| PCT/JP2004/009378 WO2005001117A1 (ja) | 2003-06-27 | 2004-06-25 | Wt1ワクチン適応患者の選択方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE538809T1 true ATE538809T1 (de) | 2012-01-15 |
Family
ID=33554467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04746847T ATE538809T1 (de) | 2003-06-27 | 2004-06-25 | Verfahren zur auswahl von geeigneten patienten für den wt1-impfstoff |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10500257B2 (de) |
| EP (3) | EP2343083B1 (de) |
| JP (1) | JP4566912B2 (de) |
| KR (2) | KR101292971B1 (de) |
| CN (1) | CN1842603B (de) |
| AT (1) | ATE538809T1 (de) |
| CA (2) | CA2530184C (de) |
| ES (3) | ES2378156T3 (de) |
| WO (1) | WO2005001117A1 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2337743C (en) * | 1998-07-31 | 2015-07-07 | Yoshihiro Oka | Tumor antigen based on products of the tumor suppressor gene wt1 |
| CN1281625C (zh) | 2001-03-22 | 2006-10-25 | 株式会社癌免疫研究所 | 经修饰的wt1肽 |
| ES2538486T3 (es) * | 2002-09-12 | 2015-06-22 | International Institute Of Cancer Immunology, Inc. | Preparación de péptidos antigénicos contra el cáncer |
| EP2343083B1 (de) | 2003-06-27 | 2014-01-15 | International Institute of Cancer Immunology, Inc. | Verfahren zum Diagnostizieren von Krebs, umfassend die Messung von WT1-spezifischen CTL-Vorläuferzellen |
| PL2071028T3 (pl) | 2003-11-05 | 2012-06-29 | Int Inst Cancer Immunology Inc | Pochodzący z WT1 peptyd antygenowy wiążący się z HLA-DR |
| DK2186896T3 (en) * | 2004-03-31 | 2015-12-21 | Int Inst Cancer Immunology Inc | Cancer antigen peptides derived from WT1 |
| CA2593714C (en) * | 2005-02-04 | 2013-09-10 | Survac Aps | Survivin peptide vaccine |
| CA2626238C (en) | 2005-10-17 | 2015-10-06 | Sloan Kettering Institute For Cancer Research | Wt1 hla class ii-binding peptides and compositions and methods comprising same |
| WO2007063903A1 (ja) * | 2005-11-30 | 2007-06-07 | International Institute Of Cancer Immunology, Inc. | 新規ペプチド化合物 |
| EP2010209B1 (de) | 2006-04-10 | 2016-06-15 | Sloan Kettering Institute For Cancer Research | Immunogene wt-1-peptide und verfahren zu ihrer verwendung |
| EP2392675A1 (de) * | 2006-06-02 | 2011-12-07 | GlaxoSmithKline Biologicals S.A. | Verfahren zur Indentifizierung des Ansprechens bzw. Nichtansprechens eines Patienten auf eine Immuntherapie basierend auf die Differentielle Expression vom Gen IFNG |
| MY158219A (en) | 2007-02-27 | 2016-09-15 | Int Inst Cancer Immunology Inc | Method for activation of helper t cell and composition for use in the method |
| EP2116596A4 (de) | 2007-03-05 | 2010-04-07 | Int Inst Cancer Immunology Inc | Krebs-antigen-spezifisches t-zellen-rezeptorgen, durch das gen kodiertes peptid und deren anwendung |
| TWI504407B (zh) | 2007-12-05 | 2015-10-21 | Int Inst Cancer Immunology Inc | 癌疫苗組合物 |
| MX361299B (es) | 2010-10-05 | 2018-11-30 | Otsuka Pharmaceutical Co Ltd Star | Metodo para activar celulas auxiliares. |
| CN107238706A (zh) | 2011-06-28 | 2017-10-10 | 株式会社癌免疫研究所 | 肽癌抗原‑特异性t细胞的受体基因 |
| EP2561759A1 (de) | 2011-08-26 | 2013-02-27 | Bayer Cropscience AG | Fluoralkyl-substituierte 2-amidobenzimidazole und ihre Wirkung auf das Pflanzenwachstum |
| US10301257B2 (en) | 2011-09-16 | 2019-05-28 | Bayer Intellectual Property Gmbh | Use of acylsulfonamides for improving plant yield |
| AU2012307322B2 (en) | 2011-09-16 | 2016-07-14 | Bayer Intellectual Property Gmbh | Use of 5-phenyl- or 5-benzyl-2 isoxazoline-3 carboxylates for improving plant yield |
| CN103781352A (zh) | 2011-09-16 | 2014-05-07 | 拜耳知识产权有限责任公司 | 苯基吡唑啉-3-甲酸酯类用于提高植物产量的用途 |
| EP3520810A3 (de) | 2012-01-13 | 2019-11-06 | Memorial Sloan-Kettering Cancer Center | Immunogene wt-1-peptide und verwendung davon |
| EP2911683B1 (de) | 2012-10-23 | 2019-09-25 | Ubivac, LLC | Mit allogenen autophagosomen angereicherte zusammensetzung zur behandlung von krankheiten |
| BR112015013697A2 (pt) | 2012-12-17 | 2017-11-14 | Univ Osaka | método para ativar célula t auxiliar |
| PL2945647T3 (pl) * | 2013-01-15 | 2021-03-08 | Memorial Sloan Kettering Cancer Center | Immunogenne peptydy wt-1 i sposoby ich zastosowania |
| US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
| CN105188375B (zh) | 2013-03-05 | 2018-04-06 | 拜耳作物科学股份公司 | 喹啉衍生物用于增加植物产量的用途 |
| HUE045111T2 (hu) | 2013-03-05 | 2019-12-30 | Bayer Cropscience Ag | N-(2-metoxibenzil)-4-[(metilaminokarbonil)amino]benzolszulfonamid inszekticidekkel vagy fungicidekkel képzett kombinációjának alkalmazása növénytermesztés hatásfokának növelésére |
| US10001491B2 (en) * | 2013-03-28 | 2018-06-19 | Centre Hospitalier Universitaire De Montpellier | Method for determining radiosensitivity |
| ES2954899T3 (es) | 2013-05-13 | 2023-11-27 | Int Inst Cancer Immunology Inc | Procedimiento para predecir el efecto clínico de una inmunoterapia |
| RS63561B1 (sr) | 2015-11-20 | 2022-10-31 | Memorial Sloan Kettering Cancer Center | Kompozicija za lečenje raka |
| EP3318135A1 (de) | 2016-11-03 | 2018-05-09 | Perfetti Van Melle S.p.A. | Sprudelndes süssigkeitenmaterial, verfahren zu dessen herstellung und daraus hergestellte produkte |
| MA51302A (fr) | 2017-12-21 | 2021-03-31 | Hoffmann La Roche | Anticorps se liant à hla-a2/wt1 |
| MX2022014249A (es) * | 2020-05-12 | 2023-02-22 | Sumitomo Pharma Co Ltd | Composición farmacéutica para tratar el cáncer. |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923799A (en) | 1984-02-06 | 1990-05-08 | The Ontario Cancer Institute | T cell specific cDNA clone |
| US6582908B2 (en) | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| CA2116526A1 (en) | 1991-08-28 | 1993-03-18 | William V. Williams | T cell receptor-based therapy for rheumatoid arthritis |
| US5364787A (en) | 1992-03-23 | 1994-11-15 | Idaho Research Foundation | Genes and enzymes involved in the microbial degradation of pentachlorophenol |
| ES2242221T3 (es) | 1996-04-16 | 2005-11-01 | Kishimoto, Tadamitsu | Procedimiento para la deteccion de celulas de cancer solido y de heterotipia histologica y procedimiento para el examen de tejidos destinados a trasplantes de medula osea y al trasplante de celulas madre sanguineas perifericas. |
| GB9710820D0 (en) | 1997-05-27 | 1997-07-23 | Univ Dundee | Immunological method |
| US6013444A (en) | 1997-09-18 | 2000-01-11 | Oligotrail, Llc | DNA bracketing locus compatible standards for electrophoresis |
| WO1999027957A1 (en) | 1997-12-03 | 1999-06-10 | The Immune Response Corporation | Vaccination and methods against multiple sclerosis using specific tcr vbeta peptides |
| WO1999060120A2 (en) | 1998-05-19 | 1999-11-25 | Avidex Limited | Soluble t cell receptor |
| CA2337743C (en) | 1998-07-31 | 2015-07-07 | Yoshihiro Oka | Tumor antigen based on products of the tumor suppressor gene wt1 |
| US20030235557A1 (en) * | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US20030072767A1 (en) * | 1998-09-30 | 2003-04-17 | Alexander Gaiger | Compositions and methods for WT1 specific immunotherapy |
| BR9914116A (pt) | 1998-09-30 | 2002-01-15 | Corixa Corp | Composições e métodos para imunoterapia especìfica de wt1 |
| GB9823897D0 (en) | 1998-11-02 | 1998-12-30 | Imp College Innovations Ltd | Immunotherapeutic methods and molecules |
| KR100479648B1 (ko) | 1999-02-23 | 2005-03-30 | 베일러 칼리지 오브 메디신 | T 세포 수용체 Vβ-Dβ-Jβ서열 및 그 검출방법 |
| WO2001094944A2 (en) * | 2000-06-02 | 2001-12-13 | Memorial Sloan-Kettering Cancer Center | Artificial antigen presenting cells and methods of use thereof |
| WO2002047474A1 (en) | 2000-12-13 | 2002-06-20 | Sumitomo Pharmaceuticals Company, Limited | Transgenic animal expressing hla-a24 and utilization thereof |
| CN1281625C (zh) | 2001-03-22 | 2006-10-25 | 株式会社癌免疫研究所 | 经修饰的wt1肽 |
| CN1320923C (zh) | 2001-06-29 | 2007-06-13 | 中外制药株式会社 | 含有基于癌抑制基因wt1的产物的癌抗原和阳离子脂质体的癌疫苗 |
| US20060035291A1 (en) | 2001-09-18 | 2006-02-16 | Kyogo Itoh | Method of detecting cellular immunity and application thereof to drugs |
| US8735357B2 (en) | 2001-09-28 | 2014-05-27 | International Institute Of Cancer Immunology, Inc. | Method of inducing antigen-specific T cells |
| EP1447092A4 (de) | 2001-09-28 | 2007-07-11 | Haruo Sugiyama | Neues verfahren zur induktion von antigenspezifischen t-zellen |
| WO2003059155A2 (en) | 2002-01-09 | 2003-07-24 | Maxx Genetech Co. Ltd | Method of detecting t-cell proliferation for diagnosis of diseases by gene array |
| JP4365784B2 (ja) * | 2002-06-12 | 2009-11-18 | 株式会社癌免疫研究所 | Hla−a24拘束性癌抗原ペプチド |
| ES2538486T3 (es) * | 2002-09-12 | 2015-06-22 | International Institute Of Cancer Immunology, Inc. | Preparación de péptidos antigénicos contra el cáncer |
| WO2004063706A2 (en) | 2003-01-08 | 2004-07-29 | Maxx Genetech Co., Ltd. | Method of detecting over-expression of t-cell receptor genes by real-time pcr |
| EP2343083B1 (de) | 2003-06-27 | 2014-01-15 | International Institute of Cancer Immunology, Inc. | Verfahren zum Diagnostizieren von Krebs, umfassend die Messung von WT1-spezifischen CTL-Vorläuferzellen |
| PL2071028T3 (pl) | 2003-11-05 | 2012-06-29 | Int Inst Cancer Immunology Inc | Pochodzący z WT1 peptyd antygenowy wiążący się z HLA-DR |
| WO2005053603A2 (en) | 2003-12-08 | 2005-06-16 | Yeda Research And Development Co. Ltd. | Antigen receptor variable region typing |
| US7576183B2 (en) | 2003-12-24 | 2009-08-18 | Los Alamos National Security, Llc | Structure-based receptor MIMICS targeted against bacterial superantigen toxins |
| DK2186896T3 (en) | 2004-03-31 | 2015-12-21 | Int Inst Cancer Immunology Inc | Cancer antigen peptides derived from WT1 |
| GB0411771D0 (en) | 2004-05-26 | 2004-06-30 | Avidex Ltd | Nucleoproteins displaying native T cell receptor libraries |
| GB0427585D0 (en) | 2004-12-16 | 2005-01-19 | Avidex Ltd | Assay |
| WO2008026927A2 (en) | 2006-08-30 | 2008-03-06 | Academisch Medisch Centrum | Process for displaying t- and b-cell receptor repertoires |
| EP2116596A4 (de) | 2007-03-05 | 2010-04-07 | Int Inst Cancer Immunology Inc | Krebs-antigen-spezifisches t-zellen-rezeptorgen, durch das gen kodiertes peptid und deren anwendung |
| JP2009278927A (ja) | 2008-05-23 | 2009-12-03 | Tohoku Univ | T細胞受容体を模倣する抗体断片及びその製造方法 |
| CN107238706A (zh) | 2011-06-28 | 2017-10-10 | 株式会社癌免疫研究所 | 肽癌抗原‑特异性t细胞的受体基因 |
-
2004
- 2004-06-25 EP EP11154325.2A patent/EP2343083B1/de not_active Expired - Lifetime
- 2004-06-25 AT AT04746847T patent/ATE538809T1/de active
- 2004-06-25 JP JP2005511121A patent/JP4566912B2/ja not_active Expired - Fee Related
- 2004-06-25 EP EP11154327.8A patent/EP2338509B1/de not_active Expired - Lifetime
- 2004-06-25 ES ES04746847T patent/ES2378156T3/es not_active Expired - Lifetime
- 2004-06-25 WO PCT/JP2004/009378 patent/WO2005001117A1/ja not_active Ceased
- 2004-06-25 CA CA2530184A patent/CA2530184C/en not_active Expired - Fee Related
- 2004-06-25 EP EP04746847A patent/EP1640458B1/de not_active Expired - Lifetime
- 2004-06-25 US US10/562,486 patent/US10500257B2/en not_active Expired - Fee Related
- 2004-06-25 CA CA2893995A patent/CA2893995A1/en not_active Abandoned
- 2004-06-25 ES ES11154325.2T patent/ES2443582T3/es not_active Expired - Lifetime
- 2004-06-25 CN CN2004800245592A patent/CN1842603B/zh not_active Expired - Fee Related
- 2004-06-25 KR KR1020057024941A patent/KR101292971B1/ko not_active Expired - Fee Related
- 2004-06-25 KR KR1020117006813A patent/KR101431312B1/ko not_active Expired - Fee Related
- 2004-06-25 ES ES11154327.8T patent/ES2478446T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2005001117A1 (ja) | 2006-08-10 |
| ES2478446T3 (es) | 2014-07-22 |
| KR20060069363A (ko) | 2006-06-21 |
| EP1640458A1 (de) | 2006-03-29 |
| EP1640458A4 (de) | 2008-05-21 |
| US20070128207A1 (en) | 2007-06-07 |
| HK1090093A1 (en) | 2006-12-15 |
| EP2343083A2 (de) | 2011-07-13 |
| EP2338509A2 (de) | 2011-06-29 |
| US10500257B2 (en) | 2019-12-10 |
| KR101292971B1 (ko) | 2013-08-12 |
| ES2378156T3 (es) | 2012-04-09 |
| JP4566912B2 (ja) | 2010-10-20 |
| WO2005001117A1 (ja) | 2005-01-06 |
| KR101431312B1 (ko) | 2014-08-20 |
| CA2893995A1 (en) | 2005-01-06 |
| EP1640458B1 (de) | 2011-12-28 |
| EP2338509A3 (de) | 2011-11-30 |
| CA2530184C (en) | 2015-10-06 |
| KR20110049877A (ko) | 2011-05-12 |
| CN1842603A (zh) | 2006-10-04 |
| EP2343083B1 (de) | 2014-01-15 |
| CA2530184A1 (en) | 2005-01-06 |
| EP2338509B1 (de) | 2014-06-18 |
| ES2443582T3 (es) | 2014-02-19 |
| EP2343083A3 (de) | 2011-08-03 |
| CN1842603B (zh) | 2013-09-11 |
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