ATE533787T1 - Hepatozytenwachstumsfaktor (hgf)-bindende proteine - Google Patents

Hepatozytenwachstumsfaktor (hgf)-bindende proteine

Info

Publication number
ATE533787T1
ATE533787T1 AT07795607T AT07795607T ATE533787T1 AT E533787 T1 ATE533787 T1 AT E533787T1 AT 07795607 T AT07795607 T AT 07795607T AT 07795607 T AT07795607 T AT 07795607T AT E533787 T1 ATE533787 T1 AT E533787T1
Authority
AT
Austria
Prior art keywords
hgf
growth factor
binding proteins
hepatocyte growth
hepatocyte
Prior art date
Application number
AT07795607T
Other languages
English (en)
Inventor
May Han
Kirk S Wright
William M Winston
Lyne Breault
Jie Lin
Bijan Etemad-Gilbertson
Christine Knuehl
Jeno Gyuris
Original Assignee
Aveo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aveo Pharmaceuticals Inc filed Critical Aveo Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE533787T1 publication Critical patent/ATE533787T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT07795607T 2006-06-02 2007-06-01 Hepatozytenwachstumsfaktor (hgf)-bindende proteine ATE533787T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81071406P 2006-06-02 2006-06-02
US86046106P 2006-11-21 2006-11-21
PCT/US2007/012950 WO2007143098A2 (en) 2006-06-02 2007-06-01 Hepatocyte growth factor (hgf) binding proteins

Publications (1)

Publication Number Publication Date
ATE533787T1 true ATE533787T1 (de) 2011-12-15

Family

ID=38802082

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07795607T ATE533787T1 (de) 2006-06-02 2007-06-01 Hepatozytenwachstumsfaktor (hgf)-bindende proteine

Country Status (16)

Country Link
US (5) US7659378B2 (de)
EP (2) EP2380908A1 (de)
JP (2) JP4560582B2 (de)
KR (1) KR101196184B1 (de)
AR (1) AR061170A1 (de)
AT (1) ATE533787T1 (de)
AU (1) AU2007254853B2 (de)
BR (1) BRPI0712223A2 (de)
CA (1) CA2654019A1 (de)
ES (1) ES2378097T3 (de)
HK (1) HK1129394A1 (de)
IL (2) IL195038A0 (de)
MX (1) MX2008015138A (de)
NO (1) NO20085422L (de)
NZ (1) NZ573819A (de)
WO (1) WO2007143098A2 (de)

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Also Published As

Publication number Publication date
WO2007143098A8 (en) 2009-01-08
WO2007143098A2 (en) 2007-12-13
NO20085422L (no) 2009-02-27
BRPI0712223A2 (pt) 2012-07-10
CA2654019A1 (en) 2007-12-13
AU2007254853A1 (en) 2007-12-13
JP5528246B2 (ja) 2014-06-25
EP2029627B1 (de) 2011-11-16
JP2009539348A (ja) 2009-11-19
NZ573819A (en) 2011-09-30
MX2008015138A (es) 2009-01-28
ES2378097T3 (es) 2012-04-04
US7659378B2 (en) 2010-02-09
US20130203970A1 (en) 2013-08-08
US20110236377A1 (en) 2011-09-29
EP2029627A2 (de) 2009-03-04
US8575318B2 (en) 2013-11-05
KR101196184B1 (ko) 2012-11-01
US20140178934A1 (en) 2014-06-26
WO2007143098A3 (en) 2008-06-12
HK1129394A1 (en) 2009-11-27
AR061170A1 (es) 2008-08-06
JP4560582B2 (ja) 2010-10-13
US20080038257A1 (en) 2008-02-14
US8268315B2 (en) 2012-09-18
US20100173361A1 (en) 2010-07-08
AU2007254853A2 (en) 2009-02-12
IL195038A0 (en) 2011-08-01
AU2007254853B2 (en) 2011-11-17
JP2010246565A (ja) 2010-11-04
KR20090026315A (ko) 2009-03-12
EP2380908A1 (de) 2011-10-26
IL219655A0 (en) 2012-06-28
US7935502B2 (en) 2011-05-03

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