ATE533471T1 - Verfahren zur herstellung von schnell auflösenden tabletten - Google Patents

Verfahren zur herstellung von schnell auflösenden tabletten

Info

Publication number
ATE533471T1
ATE533471T1 AT08719894T AT08719894T ATE533471T1 AT E533471 T1 ATE533471 T1 AT E533471T1 AT 08719894 T AT08719894 T AT 08719894T AT 08719894 T AT08719894 T AT 08719894T AT E533471 T1 ATE533471 T1 AT E533471T1
Authority
AT
Austria
Prior art keywords
mixture
fast
fast dissolving
active component
sugar alcohol
Prior art date
Application number
AT08719894T
Other languages
English (en)
Inventor
Zebunnissa Ramtoola
Ritesh Pabari
John Kelly
Original Assignee
Royal College Surgeons Ireland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38436760&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE533471(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Royal College Surgeons Ireland filed Critical Royal College Surgeons Ireland
Application granted granted Critical
Publication of ATE533471T1 publication Critical patent/ATE533471T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
AT08719894T 2007-04-03 2008-04-03 Verfahren zur herstellung von schnell auflösenden tabletten ATE533471T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07394008A EP1977734A1 (de) 2007-04-03 2007-04-03 Verfahren zur Herstellung schnelllöslicher Tabletten
US92231307P 2007-04-09 2007-04-09
PCT/IE2008/000036 WO2008120181A2 (en) 2007-04-03 2008-04-03 A method of producing fast dissolving tablets

Publications (1)

Publication Number Publication Date
ATE533471T1 true ATE533471T1 (de) 2011-12-15

Family

ID=38436760

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08719894T ATE533471T1 (de) 2007-04-03 2008-04-03 Verfahren zur herstellung von schnell auflösenden tabletten

Country Status (10)

Country Link
US (1) US20100074948A1 (de)
EP (2) EP1977734A1 (de)
JP (1) JP2010523552A (de)
CN (1) CN101720219A (de)
AT (1) ATE533471T1 (de)
AU (1) AU2008234511A1 (de)
CA (1) CA2682670A1 (de)
IL (1) IL201304A0 (de)
WO (1) WO2008120181A2 (de)
ZA (1) ZA200907685B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010540588A (ja) * 2007-10-01 2010-12-24 ラボラトリオス、レスビ、ソシエダッド、リミターダ 口腔内崩壊錠剤
WO2010077878A1 (en) * 2008-12-15 2010-07-08 Fleming And Company, Pharmaceuticals Rapidly dissolving vitamin formulation and methods of using the same
US20120077888A1 (en) * 2009-03-26 2012-03-29 Royal College Of Surgeons In Ireland Orodispersible tablets
US20140088062A1 (en) * 2011-05-23 2014-03-27 Cem-102 Pharmaceuticals, Inc. Compositions comprising fusidic acid and packages therefor
CA2963706C (en) 2014-10-16 2023-10-03 Cargill, Incorporated Process for preparing a directly compressible erythritol & uses thereof
CN106310229A (zh) * 2015-06-30 2017-01-11 深圳翰宇药业股份有限公司 一种马昔瑞林薄膜衣片及其制备方法
GB2546513B (en) 2016-01-20 2020-09-16 Cubic Pharmaceuticals Ltd Process of preparing active pharmaceutical ingredient salts
CN105878300B (zh) * 2016-04-11 2020-04-07 浙江工业大学 一种药物速溶片的制备方法
CN108853041A (zh) * 2018-08-20 2018-11-23 益奇健康科技（上海）有限公司 一种口腔速崩片
US20230292795A1 (en) * 2020-07-24 2023-09-21 Dsm Ip Assets B.V. New fast dissolvable tablets
CN112352857A (zh) * 2020-09-28 2021-02-12 苏州蓝浅信息科技有限公司 一种速溶茶片剂及其制备方法
CN115251221A (zh) * 2022-08-02 2022-11-01 青海大学 一种树莓咀嚼片及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
US5178878A (en) * 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
JP3797387B2 (ja) * 1996-06-14 2006-07-19 協和醗酵工業株式会社 口腔内速崩壊錠
US6024981A (en) * 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
AU2003222027A1 (en) * 2002-03-20 2003-10-08 Elan Pharma International Limited Fast dissolving dosage forms having reduced friability
US20030185884A1 (en) * 2002-04-01 2003-10-02 Singh Nikhilesh Nihala Therapeutic agent delivery compositions for buccal cavity absorption of pilocarpine
US20060083786A1 (en) * 2004-07-29 2006-04-20 Glenmark Pharmaceuticals Limited Taste masking pharmaceutical composition containing levocetirizine
WO2006133349A2 (en) * 2005-06-08 2006-12-14 Alpharma, Inc. Orally disintegrable sleep aid formulations

Also Published As

Publication number Publication date
WO2008120181A2 (en) 2008-10-09
WO2008120181A4 (en) 2009-02-19
EP1977734A1 (de) 2008-10-08
EP2142170B1 (de) 2011-11-16
CN101720219A (zh) 2010-06-02
EP2142170A2 (de) 2010-01-13
US20100074948A1 (en) 2010-03-25
IL201304A0 (en) 2010-05-31
JP2010523552A (ja) 2010-07-15
AU2008234511A1 (en) 2008-10-09
CA2682670A1 (en) 2008-10-09
WO2008120181A3 (en) 2008-11-27
ZA200907685B (en) 2010-07-28

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