WO2002067846A8 - A vaccine composition and method of using the same - Google Patents

A vaccine composition and method of using the same

Info

Publication number
WO2002067846A8
WO2002067846A8 PCT/IB2002/001944 IB0201944W WO02067846A8 WO 2002067846 A8 WO2002067846 A8 WO 2002067846A8 IB 0201944 W IB0201944 W IB 0201944W WO 02067846 A8 WO02067846 A8 WO 02067846A8
Authority
WO
WIPO (PCT)
Prior art keywords
vaccine
vaccine composition
composition
immunizing
compressed
Prior art date
Application number
PCT/IB2002/001944
Other languages
French (fr)
Other versions
WO2002067846A3 (en
WO2002067846A2 (en
Inventor
Gilad Gallili
Norbert Frydman
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IL15760902A priority Critical patent/IL157609A0/en
Application filed by Teva Pharma filed Critical Teva Pharma
Priority to EP02733085A priority patent/EP1370285A4/en
Priority to HU0500993A priority patent/HUP0500993A2/en
Priority to CA002438956A priority patent/CA2438956A1/en
Publication of WO2002067846A2 publication Critical patent/WO2002067846A2/en
Publication of WO2002067846A3 publication Critical patent/WO2002067846A3/en
Publication of WO2002067846A8 publication Critical patent/WO2002067846A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus

Abstract

The present invention relates to a stable compacted, compressed or hard tableted injectable composition, including a vaccine composition comprising at least one freeze dried antigenic component and a dissolution aid. A package containing the above injectable composition and method to facilitate immunizing a subject against a disease comprising the steps of first dissolving the compacted, compressed or hard tableted vaccine composition in a package with a diluent to form a vaccine solution, and administering the resulting vaccine solution in an amount effective for immunizing is also provided.
PCT/IB2002/001944 2001-02-28 2002-02-28 A vaccine composition and method of using the same WO2002067846A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IL15760902A IL157609A0 (en) 2001-02-28 2002-02-08 A vaccine composition and method of using the same
EP02733085A EP1370285A4 (en) 2001-02-28 2002-02-28 A vaccine composition and method of using the same
HU0500993A HUP0500993A2 (en) 2001-02-28 2002-02-28 A vaccine composition and method of using the same
CA002438956A CA2438956A1 (en) 2001-02-28 2002-02-28 A vaccine composition and method of using the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/795,792 US6592869B2 (en) 1999-08-24 2001-02-28 Vaccine composition and method of using the same
US09/795,792 2001-02-28

Publications (3)

Publication Number Publication Date
WO2002067846A2 WO2002067846A2 (en) 2002-09-06
WO2002067846A3 WO2002067846A3 (en) 2003-03-13
WO2002067846A8 true WO2002067846A8 (en) 2003-10-09

Family

ID=25166460

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2002/001944 WO2002067846A2 (en) 2001-02-28 2002-02-28 A vaccine composition and method of using the same

Country Status (8)

Country Link
US (2) US6592869B2 (en)
EP (1) EP1370285A4 (en)
CA (1) CA2438956A1 (en)
CZ (1) CZ20032617A3 (en)
HU (1) HUP0500993A2 (en)
IL (1) IL157609A0 (en)
WO (1) WO2002067846A2 (en)
ZA (1) ZA200306573B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000045391A1 (en) * 1999-01-29 2000-08-03 Sharper Image Corporation A rack for compact discs
US6592869B2 (en) * 1999-08-24 2003-07-15 Teva Pharmaceutical Industries, Ltd. Vaccine composition and method of using the same
US20050089502A1 (en) * 2003-08-21 2005-04-28 Todd Schansberg Effervescent delivery system
WO2005044236A1 (en) * 2003-10-27 2005-05-19 Control Delivery Systems, Inc. Suspension delivery system for the sustained and controlled local release of pharmaceuticals
JP5183068B2 (en) * 2003-12-22 2013-04-17 フィンレイ，ウォーレン，エイチ Powder formation by atmospheric spray freeze drying
WO2007014073A2 (en) * 2005-07-22 2007-02-01 Amgen Inc. Concentrated protein lyophilates, methods, and uses
DE102006054260A1 (en) * 2006-02-28 2007-09-27 Lohmann Animal Health Gmbh & Co. Kg Water stabilizing composition, process for its preparation and its use
EP2164511A1 (en) * 2007-05-22 2010-03-24 Baylor College Of Medicine Immune complex vaccination as a strategy to enhance immunity in the elderly and other immune compromised populations
GB2450117A (en) * 2007-06-13 2008-12-17 Reckitt Benckiser Healthcare A water- and oxygen-occlusive blister tablet pack
GB2451428A (en) * 2007-07-25 2009-02-04 Pliva Hrvatska D O O Process for preparing an in ovo combination viral vaccine
EP2163239A1 (en) * 2008-05-27 2010-03-17 Qiagen GmbH Products containing bioparticles, method for their manufacture
US20110020392A1 (en) * 2008-10-14 2011-01-27 Salubrious Pharmaceutical, Llc Process for treatment of rheumatoid arthritis, tremors/parkinson's disease, multiple sclerosis and non-viral based cancers
US20110110975A1 (en) * 2009-11-06 2011-05-12 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
SG190418A1 (en) 2010-12-02 2013-07-31 Oncolytics Biotech Inc Liquid viral formulations
DK2646052T3 (en) 2010-12-02 2017-07-17 Oncolytics Biotech Inc LYOPHILIZED VIRAL FORMULATIONS
WO2012123269A1 (en) 2011-03-11 2012-09-20 Proyecto De Biomedicina Cima, S.L. Immunogenic compositions and methods for their use
EP2704740B1 (en) 2011-05-04 2016-10-05 Streck, Inc. Inactivated swine flu virus and methods of preparing it
TWI745278B (en) * 2014-10-10 2021-11-11 以色列商艾畢克生物實驗有限公司 Reduced foaming vaccine compositions

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE289201C (en)
DE117250C (en)
DE106660C (en)
DE298202C (en)
DE289200C (en)
GB929377A (en) 1961-02-09 1963-06-19 Carl Peter Varnet Foot and mouth disease implantation preparations
US3317393A (en) 1964-06-08 1967-05-02 Robert M Chanock Immunization by selective infection of the intestinal tract with an encapsulated live virus
US3458621A (en) 1966-08-31 1969-07-29 American Home Prod Tablet dosage-form for the immunization of the intestinal tract with live virus preparations
US3603030A (en) 1969-08-29 1971-09-07 Remco Ind Inc Jumping toy
FR2082760A5 (en) 1970-03-26 1971-12-10 France Etat Aerosol immunisation appts - for freeze-dried vaccines
US3893280A (en) 1972-06-21 1975-07-08 Burns Biotec Lab Inc Transfer packaging for biologicals
DE2237783A1 (en) 1972-08-01 1974-02-14 Bayern Freistaat Oral smallpox vaccine compsn - protected against dissolution in the stomach
BE853923A (en) 1977-04-25 1977-10-25 Rit Rech Ind Therapeut NEW IMPROVED LIVE VACCINE AGAINST AVIAN PSEUDOPESTE AND ITS PREPARATION PROCESS
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4251509A (en) 1980-01-31 1981-02-17 Wisconsin Alumni Research Foundation Dry particulate vaccine for oral administration
US4458630A (en) 1982-06-22 1984-07-10 The United States Of America As Represented By The Secretary Of Agriculture Disease control in avian species by embryonal vaccination
HU188847B (en) * 1983-02-22 1986-05-28 Human Oltoanyagtermeloe Es Kutato Intezet,Hu Process for producing liophylized combined vaccines
IE61575B1 (en) 1987-05-04 1994-11-16 Merck & Co Inc A stable lyophilized live herpes virus vaccine
US5710014A (en) * 1988-02-11 1998-01-20 The United States Of America As Represented By The Department Of Health And Human Services Cloned cDNA for human procathepsin l.
US5472710A (en) 1988-04-16 1995-12-05 Schwarz Pharma Ag Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture
US5350741A (en) 1988-07-30 1994-09-27 Kanji Takada Enteric formulations of physiologically active peptides and proteins
DK0755684T3 (en) 1989-10-02 2001-08-20 Univ Arkansas vaccine conjugate
DK0494972T3 (en) 1989-10-02 1997-05-12 Cima Labs Inc Shower dose form and method of administration thereof
US5091188A (en) 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
FR2662942B1 (en) 1990-06-06 1992-09-18 Neway Tsehay IMMUNOSTIMULATING MEDICINE BASED ON POLAR GLYCOPEPTIDOLIPIDES OF MYCOBACTERIUM CHELONAE.
US5178882A (en) 1990-06-22 1993-01-12 The Regents Of The University Of California Viral decoy vaccine
NZ286242A (en) 1991-03-26 1997-11-24 Csl Ltd Use of veterinary implant as a single dose vaccination system: rupturable polymer film coating around core of active agent and water soluble excipient
US5206219A (en) 1991-11-25 1993-04-27 Applied Analytical Industries, Inc. Oral compositions of proteinaceous medicaments
EP0672116B1 (en) 1992-07-06 2003-06-04 President And Fellows Of Harvard College Deletion mutants as vaccines for cholera
WO1994017813A1 (en) 1993-02-08 1994-08-18 Paravax, Inc. Defective sindbis virus vectors that express toxoplasma gondii p30 antigens
US5709861A (en) * 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
JPH09503754A (en) * 1993-09-20 1997-04-15 アナデイス・リミテツド Methods for obtaining immunoglobulins from colostrum and their use in pharmaceutical compositions
US5595761A (en) 1994-01-27 1997-01-21 The Board Of Regents Of The University Of Oklahoma Particulate support matrix for making a rapidly dissolving tablet
US5576014A (en) 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
US5635210A (en) 1994-02-03 1997-06-03 The Board Of Regents Of The University Of Oklahoma Method of making a rapidly dissolving tablet
CZ297271B6 (en) 1994-07-12 2006-10-11 Bpsi Holdings, Inc. Dry moisture barrier film coating composition, method, and coated form
RU2122429C1 (en) * 1995-11-16 1998-11-27 Говоров Виктор Тимофеевич Method of preparing freeze-dried vaccine against newcastle disease virus mainly
IL120202A (en) 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
US5912014A (en) 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
HUP9902293A3 (en) * 1996-04-22 2000-04-28 Rothschild Peter R Mcallen Stabilized antihepatitis-b vaccine tablets
US5710041A (en) 1996-06-03 1998-01-20 Remel L.P. In situ reconstitutable lyophylized bacteria ampoule package
HRP970493A2 (en) 1996-09-23 1998-08-31 Wienman E. Phlips Oral delayed immediate release medical formulation and method for preparing the same
WO1998018453A1 (en) * 1996-10-28 1998-05-07 Pfizer Inc. Oral vaccines for young animals with an enteric coating
DE19741114C2 (en) 1997-09-12 2002-10-24 Riemser Arzneimittel Ag Moisture-stable and enteric drug form for fish
CU22700A1 (en) 1997-09-29 2001-07-31 Ct Ingenieria Genetica Biotech ANTI-VIRAL PHARMACEUTICAL FORMULATION CONTAINING AN ANTI-LPS PROTEIN PEPTIDE FROM LIMULUS FACTOR AND ITS USE
GB9722682D0 (en) 1997-10-27 1997-12-24 Scherer Ltd R P Pharmaceutical products
GB9801870D0 (en) 1998-01-28 1998-03-25 Raby Limited Vaccine composition
US6562002B1 (en) * 1999-02-16 2003-05-13 Prismedical Corporation Single dose delivery device
DK1212084T3 (en) * 1999-08-17 2006-07-10 Glaxosmithkline Biolog Sa Method of separating rotavirus variants as well as live attenuated rotavirus vaccine
US6592869B2 (en) * 1999-08-24 2003-07-15 Teva Pharmaceutical Industries, Ltd. Vaccine composition and method of using the same
RU2277905C2 (en) * 1999-08-24 2006-06-20 Тева Фармасьютикал Индастриз, Лтд. Vaccine composition and a method of utilization thereof

Also Published As

Publication number Publication date
US7192588B2 (en) 2007-03-20
EP1370285A2 (en) 2003-12-17
CA2438956A1 (en) 2002-09-06
US20030026813A1 (en) 2003-02-06
HUP0500993A2 (en) 2007-08-28
EP1370285A4 (en) 2005-04-13
WO2002067846A3 (en) 2003-03-13
IL157609A0 (en) 2004-03-28
US6592869B2 (en) 2003-07-15
ZA200306573B (en) 2006-10-25
CZ20032617A3 (en) 2004-08-18
WO2002067846A2 (en) 2002-09-06
US20030059435A1 (en) 2003-03-27

Similar Documents

Publication Publication Date Title
WO2002067846A8 (en) A vaccine composition and method of using the same
BRPI0014142B8 (en) stable compressed vaccine composition, and vaccination package
WO2005027895A3 (en) Thyroid hormone analogs and methods of use in angiogenesis
ECSP045496A (en) "INSULIN ACID PREPARATIONS WITH IMPROVED STABILITY"
WO2004050058A3 (en) Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
PE20020968A1 (en) ZINC-FREE AND ZINC-POOR INSULIN PREPARATIONS, WITH IMPROVED STABILITY
HK1067544A1 (en) Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
IS6719A (en) Method of analgesia
WO2003002175A8 (en) Enhanced systemic absorption of intradermally delivered substances
EP1159964A3 (en) Compositions and methods for stimulating gastrointestinal motility
UA90518C2 (en) Pharmaceutical composition in the form of a tablet suitable for dissolution in the buccal cavity, comprising a narcotic active ingredient and amine
WO2002080965A3 (en) Vaccine composition
WO2006085983A3 (en) Viral adjuvants
DK1835939T3 (en) Meningococcal conjugate vaccination
RU2006139000A (en) DEFERASYROX DISPERSABLE TABLETS
MXPA02009275A (en) Method for preparing high pressure high shear dispersions containing physiologically active ingredients.
WO2005065708A3 (en) Formulations of hydrophobic proteins in an immunogenic composition having improved tolerability
EP1291362A4 (en) A complex between folic acid and polysaccharides, its preparation method and a pharmaceutical composition comprising said complex as active component
WO2002015933A3 (en) Combination comprising an at1-receptor antagonist and an insulin secretion enhancer or an insulin sensitiser
WO2001085139A3 (en) Semi-solid delivery vehicle and pharmaceutical compositions
EP1258254A4 (en) Sustained release preparations of physiologically active compound hardly soluble in water and production process and use of the same
WO2006114312A3 (en) Vaccine
WO2001080619A3 (en) Pharmaceutical composition containing citalopram
WO1997048382A3 (en) Multiple-unit type prolonged action drug preparation
WO2003045326A3 (en) Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 2438956

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2003/06573

Country of ref document: ZA

Ref document number: 2002304309

Country of ref document: AU

Ref document number: 200306573

Country of ref document: ZA

WWE Wipo information: entry into national phase

Ref document number: 157609

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 01388/DELNP/2003

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2002733085

Country of ref document: EP

Ref document number: PV2003-2617

Country of ref document: CZ

WWP Wipo information: published in national office

Ref document number: 2002733085

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: PV2003-2617

Country of ref document: CZ

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Ref document number: JP