ATE531719T1 - Neue synthese einer camptothecin-untereinheit - Google Patents
Neue synthese einer camptothecin-untereinheitInfo
- Publication number
- ATE531719T1 ATE531719T1 AT06706913T AT06706913T ATE531719T1 AT E531719 T1 ATE531719 T1 AT E531719T1 AT 06706913 T AT06706913 T AT 06706913T AT 06706913 T AT06706913 T AT 06706913T AT E531719 T1 ATE531719 T1 AT E531719T1
- Authority
- AT
- Austria
- Prior art keywords
- camptothecin
- subunit
- new synthesis
- manufacture
- compound
- Prior art date
Links
- KLWPJMFMVPTNCC-UHFFFAOYSA-N Camptothecin Natural products CCC1(O)C(=O)OCC2=C1C=C3C4Nc5ccccc5C=C4CN3C2=O KLWPJMFMVPTNCC-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical compound C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title 1
- 229940127093 camptothecin Drugs 0.000 title 1
- VSJKWCGYPAHWDS-UHFFFAOYSA-N dl-camptothecin Natural products C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)C5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-UHFFFAOYSA-N 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- FBDOJYYTMIHHDH-OZBJMMHXSA-N (19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-2,4,6,8,10,14,20-heptaen-18-one Chemical compound CC[C@@]1(O)C(=O)OCC2=CN3Cc4cc5ccccc5nc4C3C=C12 FBDOJYYTMIHHDH-OZBJMMHXSA-N 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229940041181 antineoplastic drug Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05101338 | 2005-02-22 | ||
| PCT/EP2006/001306 WO2006089657A1 (en) | 2005-02-22 | 2006-02-14 | New synthesis of a camptothecin subunit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE531719T1 true ATE531719T1 (de) | 2011-11-15 |
Family
ID=36177738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06706913T ATE531719T1 (de) | 2005-02-22 | 2006-02-14 | Neue synthese einer camptothecin-untereinheit |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7423152B2 (enExample) |
| EP (1) | EP1856124B1 (enExample) |
| JP (1) | JP4861340B2 (enExample) |
| KR (1) | KR100916175B1 (enExample) |
| CN (1) | CN101128467B (enExample) |
| AT (1) | ATE531719T1 (enExample) |
| CA (1) | CA2597388A1 (enExample) |
| IL (1) | IL185015A (enExample) |
| MX (1) | MX2007010033A (enExample) |
| TW (1) | TWI314932B (enExample) |
| WO (1) | WO2006089657A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7632540B2 (en) * | 2003-07-01 | 2009-12-15 | Transitions Optical, Inc. | Alignment facilities for optical dyes |
| CN104277144A (zh) * | 2008-07-31 | 2015-01-14 | 卢布里佐尔公司 | 共聚物及其润滑组合物 |
| CN101544651B (zh) * | 2009-04-24 | 2011-11-02 | 华东师范大学 | 多取代吡啶酮化合物的合成方法 |
| CN101591342B (zh) * | 2009-07-03 | 2011-07-27 | 华东师范大学 | 用于喜树碱类化合物制备的关键中间体合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5162532A (en) * | 1990-12-20 | 1992-11-10 | North Carolina State University | Intermediates and method of making camptothecin and camptothecin analogs |
| US5491237A (en) * | 1994-05-03 | 1996-02-13 | Glaxo Wellcome Inc. | Intermediates in pharmaceutical camptothecin preparation |
-
2006
- 2006-02-14 MX MX2007010033A patent/MX2007010033A/es active IP Right Grant
- 2006-02-14 KR KR1020077019083A patent/KR100916175B1/ko not_active Expired - Fee Related
- 2006-02-14 JP JP2007555511A patent/JP4861340B2/ja not_active Expired - Fee Related
- 2006-02-14 WO PCT/EP2006/001306 patent/WO2006089657A1/en not_active Ceased
- 2006-02-14 EP EP06706913A patent/EP1856124B1/en not_active Not-in-force
- 2006-02-14 AT AT06706913T patent/ATE531719T1/de active
- 2006-02-14 CN CN2006800056195A patent/CN101128467B/zh not_active Expired - Fee Related
- 2006-02-14 CA CA002597388A patent/CA2597388A1/en not_active Abandoned
- 2006-02-17 US US11/357,273 patent/US7423152B2/en not_active Expired - Fee Related
- 2006-02-20 TW TW095105638A patent/TWI314932B/zh not_active IP Right Cessation
-
2007
- 2007-08-02 IL IL185015A patent/IL185015A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101128467A (zh) | 2008-02-20 |
| EP1856124B1 (en) | 2011-11-02 |
| US20060189807A1 (en) | 2006-08-24 |
| WO2006089657A1 (en) | 2006-08-31 |
| JP2008531487A (ja) | 2008-08-14 |
| TW200640935A (en) | 2006-12-01 |
| IL185015A (en) | 2012-07-31 |
| KR20070104424A (ko) | 2007-10-25 |
| JP4861340B2 (ja) | 2012-01-25 |
| MX2007010033A (es) | 2007-10-04 |
| TWI314932B (en) | 2009-09-21 |
| KR100916175B1 (ko) | 2009-09-08 |
| CA2597388A1 (en) | 2006-08-31 |
| EP1856124A1 (en) | 2007-11-21 |
| IL185015A0 (en) | 2007-12-03 |
| US7423152B2 (en) | 2008-09-09 |
| CN101128467B (zh) | 2010-12-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA06010097A (es) | Inhibidores de dipeptidil peptidasa-iv. | |
| DK1814846T3 (da) | 11beta-HSD1-inhibitorer | |
| CY1111045T1 (el) | Μεθοδος παραγωγης ενος παραγωγου βενζιμιδαζολιου | |
| TNSN07360A1 (en) | Substituted pyrrolo-pyridines, composition containing them, method for their producing and use thereof | |
| SI2091948T1 (sl) | Novi inhibitorji glutaminil ciklaze | |
| MEP58808A (en) | Dihydropteridinones, method for the production and use thereof in the form of drugs | |
| NO20073701L (no) | Nye fremgangsmater for fremstilling av et 2H-kromen | |
| MX2009007436A (es) | Derivados espirociclicos de acido tetronico. | |
| MX2009007387A (es) | Derivados de ciclohexano espirociclicos. | |
| ATE519373T1 (de) | Teezusammensetzung und herstellungsverfahren dafür | |
| MY153763A (en) | Quinazolinedione derivatives, preparation thereof and therapeutic uses thereof | |
| SG158848A1 (en) | Method for producing annelated piperazin-2-one derivatives and intermediates of said method | |
| DE602007013077D1 (de) | Organische verbindungen | |
| DE502005008057D1 (de) | Substituierte cyclopenten-verbindungen | |
| IL185015A0 (en) | New synthesis of a camptothecin subunit | |
| CY1107101T1 (el) | Μεθοδος συνθεσης παραγωγων της 1,3-διϋδρο-2h-3-βενζαζεπιν-2-ονης και εφαρμογη στη συνθεση της ιβαβραδινης και των αλατων προσθηκης με φαρμακευτικως αποδεκτο οξυ | |
| ATE550326T1 (de) | Als modulatoren von hdl einsetzbare verbindungen | |
| DK1831239T5 (da) | Fremgangsmåde til fremstilling af 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta -bismethylen-17alpha-pregn-4-en-3-on-21-carboxylsyre-gamma-lacton og nøgle-mellemprodukter til denne fremgangsmåde | |
| TW200726752A (en) | Process for the production of intermediates for the preparation of tricyclic benzimidazoles | |
| BRPI0606659A2 (pt) | processos para a preparação de álcoois aminoetoxibenzìlicos | |
| MX2009003106A (es) | Nueva modificacion cristalina de 4-(n-metil-2-cloro-5-piridilmetil amino)-2,5-dihidrofuran-2-ona. | |
| TW200738681A (en) | Isoquinoline and benzo[h]isoquinoline derivatives, their preparation and their use in therapeutics | |
| EA200702428A1 (ru) | Способы получения 4-бифенилилазетидин-2-онов | |
| ATE388154T1 (de) | Kristalline form von cefdinir-ammoniumsalz als zwischenprodukt für die herstellung von reinem cefdinir | |
| GB0710700D0 (en) | Organic compounds |