ATE525635T1 - Ionenmobilitätsanalyse biologischer partikel - Google Patents

Ionenmobilitätsanalyse biologischer partikel

Info

Publication number
ATE525635T1
ATE525635T1 AT02789660T AT02789660T ATE525635T1 AT E525635 T1 ATE525635 T1 AT E525635T1 AT 02789660 T AT02789660 T AT 02789660T AT 02789660 T AT02789660 T AT 02789660T AT E525635 T1 ATE525635 T1 AT E525635T1
Authority
AT
Austria
Prior art keywords
densities
biological particles
lipoprotein
analytical
ion mobility
Prior art date
Application number
AT02789660T
Other languages
English (en)
Inventor
W Benner
Ronald Krauss
Patricia Blanche
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE525635T1 publication Critical patent/ATE525635T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0266—Investigating particle size or size distribution with electrical classification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT02789660T 2001-11-13 2002-11-12 Ionenmobilitätsanalyse biologischer partikel ATE525635T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33821401P 2001-11-13 2001-11-13
PCT/US2002/036645 WO2003042704A1 (en) 2001-11-13 2002-11-12 Ion mobility analysis of biological particles

Publications (1)

Publication Number Publication Date
ATE525635T1 true ATE525635T1 (de) 2011-10-15

Family

ID=23323894

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02789660T ATE525635T1 (de) 2001-11-13 2002-11-12 Ionenmobilitätsanalyse biologischer partikel

Country Status (7)

Country Link
US (4) US7259018B2 (de)
EP (1) EP1444526B1 (de)
JP (1) JP4705754B2 (de)
AT (1) ATE525635T1 (de)
AU (2) AU2002352712B2 (de)
CA (1) CA2467420A1 (de)
WO (1) WO2003042704A1 (de)

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JP2007524964A (ja) * 2003-06-20 2007-08-30 ブリガム・ヤング・ユニバーシティ イオン移動度分析及びイオントラップ質量分析のための単一装置
JP3819895B2 (ja) * 2003-10-29 2006-09-13 大塚電子株式会社 動脈硬化評価装置
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US20050109856A1 (en) * 2003-11-25 2005-05-26 Alexander James N.Iv Method for preparing polymer electrosprays
EP1564780A3 (de) * 2003-12-08 2006-05-31 Rohm And Haas Company Vorrichtung zur Bestimmung der Molekulargewichte von Polymeren
US20050164398A1 (en) * 2004-01-26 2005-07-28 Alexander James N.Iv Method for determining molecular weight of polymers
KR100567788B1 (ko) * 2004-02-13 2006-04-05 주식회사 현대교정인증기술원 입자측정기 및 입자측정방법
US8884221B2 (en) * 2006-01-05 2014-11-11 Excellims Corporation High performance ion mobility spectrometer apparatus and methods
US20080302666A1 (en) * 2007-06-08 2008-12-11 Benner W Henry Apparatus for differential charged-particle mobility
EP2645102A3 (de) * 2007-06-08 2014-01-22 Quest Diagnostics Investments Incorporated Lipoproteinanalyse durch differentielle Mobilität für geladene Teilchen
US8247235B2 (en) 2007-06-08 2012-08-21 Quest Diagnostics Investments Incorporated Lipoprotein analysis by differential charged-particle mobility
US20090078064A1 (en) * 2007-08-06 2009-03-26 Abraham Oommen Instrument for simultaneous analysis of multiple samples using multiple differential mobility analyzers
WO2009109037A1 (en) * 2008-03-07 2009-09-11 The University Of British Colu Self-contained capillary electrophoresis system for interfacing with mass spectrometry
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WO2010047767A2 (en) * 2008-10-20 2010-04-29 Liposcience, Inc. Lipoprotein insulin resistance indexes and related methods, systems and computer programs for generating same
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JP2012530900A (ja) * 2009-06-17 2012-12-06 メイン スタンダーズ カンパニー リミテッド ライアビリティ カンパニー リポタンパク質特異的アポリポタンパク質を測定する方法
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US9702807B2 (en) 2012-06-16 2017-07-11 Ningbo Alabama, Llc Measurement of serum lipoproteins
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US9459194B2 (en) * 2013-03-14 2016-10-04 Cardio Metrix Apparatuses, processes, and systems for measuring particle size distribution and concentration
US9551768B2 (en) 2013-03-15 2017-01-24 East Carolina University NMR method for monitoring changes in the core of lipoprotein particles in metabolism and disease
WO2014168043A1 (ja) * 2013-04-09 2014-10-16 東京エレクトロン株式会社 測定装置及び測定方法
TWI549745B (zh) 2014-05-16 2016-09-21 財團法人工業技術研究院 溶液混合裝置與混合方法以及溶液粒子監測系統與監測方法
JP6814732B2 (ja) * 2014-09-11 2021-01-20 リポサイエンス，インコーポレイテッド Ｈｄｌおよび炎症性バイオマーカインタラクションパラメータを含むリスクパラメータを用いた心血管リスク評価
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EP3685168A1 (de) * 2017-09-20 2020-07-29 The Trustees Of Indiana University Verfahren zur auflösung von lipoproteinen mit massenspektrometrie
EP3738137A1 (de) 2018-01-12 2020-11-18 The Trustees of Indiana University Konstruktion einer elektrostatischen linearen ionenfalle für massenspektrometrie mit ladungsdetektion
US10775458B2 (en) 2018-03-05 2020-09-15 Texas Tech University System Method and system for non-invasive measurement of metabolic health
JP7398810B2 (ja) 2018-06-04 2023-12-15 ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー 静電線形イオン・トラップにイオンを捕獲する装置および方法
WO2019236140A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Charge detection mass spectrometry with real time analysis and signal optimization
KR102742960B1 (ko) 2018-06-04 2024-12-16 더 트러스티즈 오브 인디애나 유니버시티 높은 스루풋 전하 검출 질량 분광분석법을 위한 이온 트랩 어레이
WO2019236143A1 (en) 2018-06-04 2019-12-12 The Trustees Of Indiana University Apparatus and method for calibrating or resetting a charge detector
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EP4443473A3 (de) 2018-12-03 2025-01-01 The Trustees of Indiana University Vorrichtung zur gleichzeitigen analyse mehrerer ionen mit einer elektrostatischen linearen ionenfalle
EP3959741A1 (de) 2019-04-23 2022-03-02 The Trustees of Indiana University Identifizierung von probensubspezies basierend auf partikelladungsverhalten unter strukturveränderungen induzierenden probenbedingungen
CA3156003A1 (en) 2019-09-25 2021-04-01 The Trustees Of Indiana University Apparatus and method for pulsed mode charge detection mass spectrometry
EP4041434A4 (de) 2019-10-10 2023-11-08 The Trustees of Indiana University System und verfahren zur identifizierung, auswahl und reinigung von partikeln
CA3165106A1 (en) 2019-12-18 2021-06-24 The Trustees Of Indiana University Mass spectrometer with charge measurement arrangement
EP4100991B1 (de) 2020-02-03 2025-01-29 The Trustees of Indiana University Ein massenspektrometer zur ladungsdetektion und entsprechende methode
WO2021191266A1 (en) * 2020-03-25 2021-09-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Aerosolization of hdl for the treatment of lung infections
CN112798481B (zh) * 2020-10-27 2022-02-18 美康生物科技股份有限公司 一种用于检测脂蛋白颗粒浓度的试剂及其使用方法
US12379296B2 (en) * 2020-11-26 2025-08-05 12535441 Canada Ltd. Spectral diagnostic system
CN115773977B (zh) * 2022-12-01 2023-07-18 中国计量科学研究院 基于es-dma-cpc颗粒计数的蛋白质定量方法

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Also Published As

Publication number Publication date
EP1444526B1 (de) 2011-09-21
WO2003042704A1 (en) 2003-05-22
EP1444526A1 (de) 2004-08-11
US8097462B2 (en) 2012-01-17
US7259018B2 (en) 2007-08-21
JP4705754B2 (ja) 2011-06-22
AU2009200225A1 (en) 2009-02-12
AU2002352712A2 (en) 2003-05-26
US20030136680A1 (en) 2003-07-24
US20110089037A1 (en) 2011-04-21
US20070287187A1 (en) 2007-12-13
CA2467420A1 (en) 2003-05-22
JP2005509860A (ja) 2005-04-14
US7851224B2 (en) 2010-12-14
AU2002352712B2 (en) 2008-10-30
US7713744B2 (en) 2010-05-11
EP1444526A4 (de) 2007-08-22
US20100213061A1 (en) 2010-08-26

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