ATE525635T1 - Ionenmobilitätsanalyse biologischer partikel - Google Patents

Ionenmobilitätsanalyse biologischer partikel

Info

Publication number
ATE525635T1
ATE525635T1 AT02789660T AT02789660T ATE525635T1 AT E525635 T1 ATE525635 T1 AT E525635T1 AT 02789660 T AT02789660 T AT 02789660T AT 02789660 T AT02789660 T AT 02789660T AT E525635 T1 ATE525635 T1 AT E525635T1
Authority
AT
Austria
Prior art keywords
densities
biological particles
lipoprotein
analytical
ion mobility
Prior art date
Application number
AT02789660T
Other languages
English (en)
Inventor
W Benner
Ronald Krauss
Patricia Blanche
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE525635T1 publication Critical patent/ATE525635T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0266—Investigating particle size or size distribution with electrical classification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT02789660T 2001-11-13 2002-11-12 Ionenmobilitätsanalyse biologischer partikel ATE525635T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33821401P 2001-11-13 2001-11-13
PCT/US2002/036645 WO2003042704A1 (en) 2001-11-13 2002-11-12 Ion mobility analysis of biological particles

Publications (1)

Publication Number Publication Date
ATE525635T1 true ATE525635T1 (de) 2011-10-15

Family

ID=23323894

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02789660T ATE525635T1 (de) 2001-11-13 2002-11-12 Ionenmobilitätsanalyse biologischer partikel

Country Status (7)

Country Link
US (4) US7259018B2 (de)
EP (1) EP1444526B1 (de)
JP (1) JP4705754B2 (de)
AT (1) ATE525635T1 (de)
AU (2) AU2002352712B2 (de)
CA (1) CA2467420A1 (de)
WO (1) WO2003042704A1 (de)

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US20040043496A1 (en) * 2002-06-21 2004-03-04 Berkeley Heartlab, Inc. Method for identifying patients who will require multiple invasive cardiovascular procedures
EP1614141A4 (de) * 2003-04-09 2007-09-12 Univ Brigham Young Querströmungsionenmobilitätsanalysator
CN1829911B (zh) * 2003-06-20 2011-04-20 杨百翰大学 用于离子迁移率和离子阱质谱分析的单一装置
JP3819895B2 (ja) * 2003-10-29 2006-09-13 大塚電子株式会社 動脈硬化評価装置
US20050109856A1 (en) * 2003-11-25 2005-05-26 Alexander James N.Iv Method for preparing polymer electrosprays
JP4802104B2 (ja) * 2003-11-25 2011-10-26 サイオネックス コーポレイション サンプルの分析を改善するための分散特性、サンプル解離及び／又は圧力制御を用いた移動度ベースの装置及び方法
EP1564780A3 (de) * 2003-12-08 2006-05-31 Rohm And Haas Company Vorrichtung zur Bestimmung der Molekulargewichte von Polymeren
US20050164398A1 (en) * 2004-01-26 2005-07-28 Alexander James N.Iv Method for determining molecular weight of polymers
KR100567788B1 (ko) * 2004-02-13 2006-04-05 주식회사 현대교정인증기술원 입자측정기 및 입자측정방법
US8884221B2 (en) * 2006-01-05 2014-11-11 Excellims Corporation High performance ion mobility spectrometer apparatus and methods
US20080302666A1 (en) * 2007-06-08 2008-12-11 Benner W Henry Apparatus for differential charged-particle mobility
EP2645107B1 (de) * 2007-06-08 2018-02-28 Quest Diagnostics Investments Incorporated Verfahren zum Aufreinigen von Lipoproteinen geeignet für die Analyse durch differentielle Mobilität für geladene Teilchen
US8247235B2 (en) * 2007-06-08 2012-08-21 Quest Diagnostics Investments Incorporated Lipoprotein analysis by differential charged-particle mobility
US20090078064A1 (en) * 2007-08-06 2009-03-26 Abraham Oommen Instrument for simultaneous analysis of multiple samples using multiple differential mobility analyzers
US8613845B2 (en) * 2008-03-07 2013-12-24 The University Of British Columbia Self contained capillary electrophoresis system for interfacing with mass spectrometry
US9354200B1 (en) 2008-08-07 2016-05-31 Quest Diagnostics Investments Incorporated Detection apparatus for differential-charged particle mobility analyzer
KR20110086074A (ko) * 2008-10-20 2011-07-27 리포사이언스, 인크. 지질단백질 인슐린 저항성 지표 및 이와 관련된 방법, 시스템 및 이를 생성하기 위한 컴퓨터 프로그램
WO2010136633A1 (en) * 2009-05-26 2010-12-02 Tampereen Teknillinen Yliopisto Method and apparatus for generating test aerosol
JP2012530900A (ja) * 2009-06-17 2012-12-06 メイン スタンダーズ カンパニー リミテッド ライアビリティ カンパニー リポタンパク質特異的アポリポタンパク質を測定する方法
US9638705B2 (en) * 2010-11-01 2017-05-02 Quest Diagnostics Investments Incorporated Prognostic assays for maintenance hemodialysis patients
US9250211B2 (en) 2010-12-30 2016-02-02 Quest Diagnostics Investments Incorporated Magnetic separation of lipoproteins using dextran sulfate
US9239279B1 (en) * 2011-06-03 2016-01-19 Arkansas State University—Jonesboro Sequential differential mobility analyzer and method of using same
US9322833B2 (en) * 2011-06-16 2016-04-26 Children's Hospital & Research Center At Oakland Ultra-small ApoB-containing particles and methods of use thereof
US9239280B2 (en) 2012-06-16 2016-01-19 Atherotech, Inc. Measurement of serum lipoproteins
WO2013188879A1 (en) * 2012-06-16 2013-12-19 Atherotech, Inc. Measurement of serum lipoproteins
US9459194B2 (en) * 2013-03-14 2016-10-04 Cardio Metrix Apparatuses, processes, and systems for measuring particle size distribution and concentration
US9551768B2 (en) 2013-03-15 2017-01-24 East Carolina University NMR method for monitoring changes in the core of lipoprotein particles in metabolism and disease
WO2014168043A1 (ja) * 2013-04-09 2014-10-16 東京エレクトロン株式会社 測定装置及び測定方法
TWI549745B (zh) 2014-05-16 2016-09-21 財團法人工業技術研究院 溶液混合裝置與混合方法以及溶液粒子監測系統與監測方法
JP6814732B2 (ja) 2014-09-11 2021-01-20 リポサイエンス，インコーポレイテッド Ｈｄｌおよび炎症性バイオマーカインタラクションパラメータを含むリスクパラメータを用いた心血管リスク評価
KR102222931B1 (ko) * 2016-04-01 2021-03-04 티에스아이 인코포레이티드 응축 파티클 카운터에서의 오류 카운트의 감소
WO2019060538A1 (en) * 2017-09-20 2019-03-28 The Trustees Of Indiana University METHODS FOR LIPOPROTEIN RESOLUTION BY MASS SPECTROMETRY
US11232941B2 (en) 2018-01-12 2022-01-25 The Trustees Of Indiana University Electrostatic linear ion trap design for charge detection mass spectrometry
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CA3118267A1 (en) 2018-11-20 2020-05-28 The Trustees Of Indiana University Orbitrap for single particle mass spectrometry
CA3118567A1 (en) 2018-12-03 2020-06-11 The Trustees Of Indiana University Apparatus and method for simultaneously analyzing multiple ions with an electrostatic linear ion trap
CA3137876A1 (en) 2019-04-23 2020-10-29 The Trustees Of Indiana University Identification of sample subspecies based on particle charge behavior under structural change-inducing sample conditions
WO2021191266A1 (en) * 2020-03-25 2021-09-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Aerosolization of hdl for the treatment of lung infections
CN112798481B (zh) * 2020-10-27 2022-02-18 美康生物科技股份有限公司 一种用于检测脂蛋白颗粒浓度的试剂及其使用方法
CN115773977B (zh) * 2022-12-01 2023-07-18 中国计量科学研究院 基于es-dma-cpc颗粒计数的蛋白质定量方法

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Also Published As

Publication number Publication date
JP4705754B2 (ja) 2011-06-22
AU2002352712A2 (en) 2003-05-26
WO2003042704A1 (en) 2003-05-22
US7851224B2 (en) 2010-12-14
EP1444526A4 (de) 2007-08-22
US20100213061A1 (en) 2010-08-26
US7259018B2 (en) 2007-08-21
CA2467420A1 (en) 2003-05-22
AU2002352712B2 (en) 2008-10-30
AU2009200225A1 (en) 2009-02-12
EP1444526B1 (de) 2011-09-21
EP1444526A1 (de) 2004-08-11
US20070287187A1 (en) 2007-12-13
US8097462B2 (en) 2012-01-17
US20030136680A1 (en) 2003-07-24
US20110089037A1 (en) 2011-04-21
JP2005509860A (ja) 2005-04-14
US7713744B2 (en) 2010-05-11

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