ATE524170T1 - Östrogenrezeptor modulatoren - Google Patents

Östrogenrezeptor modulatoren

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Publication number
ATE524170T1
ATE524170T1 AT01912748T AT01912748T ATE524170T1 AT E524170 T1 ATE524170 T1 AT E524170T1 AT 01912748 T AT01912748 T AT 01912748T AT 01912748 T AT01912748 T AT 01912748T AT E524170 T1 ATE524170 T1 AT E524170T1
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Austria
Prior art keywords
estrogen
receptor modulators
compounds
estrogen receptor
functioning
Prior art date
Application number
AT01912748T
Other languages
English (en)
Inventor
Dann Parker
Ronald RATCLIFFE
Robert WILKENING
Kenneth Wildonger
Original Assignee
Merck Sharp & Dohme
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Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
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Publication of ATE524170T1 publication Critical patent/ATE524170T1/de

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    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
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AT01912748T 2000-02-14 2001-02-14 Östrogenrezeptor modulatoren ATE524170T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18237200P 2000-02-14 2000-02-14
PCT/US2001/004831 WO2001082923A1 (en) 2000-02-14 2001-02-14 Estrogen receptor modulators

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ATE524170T1 true ATE524170T1 (de) 2011-09-15

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US (2) US7087599B2 (de)
EP (1) EP1257264B1 (de)
JP (1) JP4331913B2 (de)
AT (1) ATE524170T1 (de)
AU (1) AU784200B2 (de)
CA (1) CA2400626C (de)
HK (1) HK1048592A1 (de)
WO (1) WO2001082923A1 (de)

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US7157604B2 (en) 2001-08-13 2007-01-02 Merck & Co., Inc. Selective estrogen receptor modulators
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WO2005094833A1 (en) * 2004-03-31 2005-10-13 Council Of Scientific And Industrial Research Novel n-substituted dihydrobenzothiepino, dihydrobenzoxepino and tetrahydro benzocyclohepta indoles as selective estrogen receptor modulators
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AR051597A1 (es) * 2004-11-01 2007-01-24 Merck & Co Inc Moduladores de los receptores de estrogeno
WO2006050399A2 (en) * 2004-11-01 2006-05-11 Merck & Co., Inc. Synthesis of 1,5-disubstituted-2-hydroxy-gibbatetraen-6-ones
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