ATE520688T1 - Verfahren zur herstellung von darifenacin- wasserstoff-bromid - Google Patents
Verfahren zur herstellung von darifenacin- wasserstoff-bromidInfo
- Publication number
- ATE520688T1 ATE520688T1 AT09705800T AT09705800T ATE520688T1 AT E520688 T1 ATE520688 T1 AT E520688T1 AT 09705800 T AT09705800 T AT 09705800T AT 09705800 T AT09705800 T AT 09705800T AT E520688 T1 ATE520688 T1 AT E520688T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen bromide
- darifenacin
- producing
- pyrrolidine
- base
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CZ20080045A CZ300895B6 (cs) | 2008-01-28 | 2008-01-28 | Zpusob prípravy Darifenacinu |
PCT/CZ2009/000003 WO2009094957A1 (en) | 2008-01-28 | 2009-01-14 | A method for the preparation of darifenacin hydrogen bromide |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE520688T1 true ATE520688T1 (de) | 2011-09-15 |
Family
ID=40512484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT09705800T ATE520688T1 (de) | 2008-01-28 | 2009-01-14 | Verfahren zur herstellung von darifenacin- wasserstoff-bromid |
Country Status (8)
Country | Link |
---|---|
US (1) | US20100317871A1 (de) |
EP (1) | EP2238129B1 (de) |
AT (1) | ATE520688T1 (de) |
CZ (1) | CZ300895B6 (de) |
EA (1) | EA017928B1 (de) |
PL (1) | PL2238129T3 (de) |
UA (1) | UA99640C2 (de) |
WO (1) | WO2009094957A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011070419A1 (en) * | 2009-12-10 | 2011-06-16 | Aurobindo Pharma Limited | An improved process for the preparation of darifenacin hydrobromide |
CN107721955B (zh) * | 2016-11-30 | 2019-10-11 | 内蒙古京东药业有限公司 | 达非那新中间体2,3-二氢-5-苯并呋喃乙酸的制备新方法 |
CN107721954B (zh) * | 2016-11-30 | 2020-02-14 | 内蒙古京东药业有限公司 | 达非那新中间体2,3-二氢-5-苯并呋喃乙酸的制备新方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8906166D0 (en) * | 1989-03-17 | 1989-05-04 | Pfizer Ltd | Therapeutic agents |
GB9518953D0 (en) * | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
GB0129962D0 (en) * | 2001-12-14 | 2002-02-06 | Pfizer Ltd | Method of treatment |
GB0207104D0 (en) * | 2002-03-26 | 2002-05-08 | Pfizer Ltd | Stable hydrate of a muscarinic receptor antagonist |
US20070197630A1 (en) * | 2005-12-27 | 2007-08-23 | Valeriano Merli | Pure darifenacin hydrobromide substantially free of oxidized darifenacin and salts thereof and processes for the preparation thereof |
-
2008
- 2008-01-28 CZ CZ20080045A patent/CZ300895B6/cs not_active IP Right Cessation
-
2009
- 2009-01-14 AT AT09705800T patent/ATE520688T1/de not_active IP Right Cessation
- 2009-01-14 EA EA201001191A patent/EA017928B1/ru not_active IP Right Cessation
- 2009-01-14 EP EP09705800A patent/EP2238129B1/de active Active
- 2009-01-14 PL PL09705800T patent/PL2238129T3/pl unknown
- 2009-01-14 US US12/863,894 patent/US20100317871A1/en not_active Abandoned
- 2009-01-14 WO PCT/CZ2009/000003 patent/WO2009094957A1/en active Application Filing
- 2009-01-14 UA UAA201010440A patent/UA99640C2/ru unknown
Also Published As
Publication number | Publication date |
---|---|
PL2238129T3 (pl) | 2011-12-30 |
US20100317871A1 (en) | 2010-12-16 |
EP2238129B1 (de) | 2011-08-17 |
EA201001191A1 (ru) | 2010-12-30 |
CZ200845A3 (cs) | 2009-09-02 |
EP2238129A1 (de) | 2010-10-13 |
UA99640C2 (ru) | 2012-09-10 |
EA017928B1 (ru) | 2013-04-30 |
WO2009094957A1 (en) | 2009-08-06 |
CZ300895B6 (cs) | 2009-09-02 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |