ATE517646T1 - Gewebereparaturzusammensetzungen und verfahren für ihre herstellung und verwendung - Google Patents
Gewebereparaturzusammensetzungen und verfahren für ihre herstellung und verwendungInfo
- Publication number
- ATE517646T1 ATE517646T1 AT02759522T AT02759522T ATE517646T1 AT E517646 T1 ATE517646 T1 AT E517646T1 AT 02759522 T AT02759522 T AT 02759522T AT 02759522 T AT02759522 T AT 02759522T AT E517646 T1 ATE517646 T1 AT E517646T1
- Authority
- AT
- Austria
- Prior art keywords
- soluble
- extraction product
- product
- production
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/365—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Dispersion Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31600501P | 2001-08-30 | 2001-08-30 | |
US10/195,671 US7132110B2 (en) | 2001-08-30 | 2002-07-15 | Tissue repair compositions and methods for their manufacture and use |
PCT/US2002/027908 WO2003020117A2 (en) | 2001-08-30 | 2002-08-30 | Tissue repair compositions and methods for their manufacture and use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE517646T1 true ATE517646T1 (de) | 2011-08-15 |
Family
ID=26891211
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02759522T ATE517646T1 (de) | 2001-08-30 | 2002-08-30 | Gewebereparaturzusammensetzungen und verfahren für ihre herstellung und verwendung |
Country Status (9)
Country | Link |
---|---|
US (2) | US7132110B2 (de) |
EP (1) | EP1453434B1 (de) |
KR (1) | KR20040048403A (de) |
AT (1) | ATE517646T1 (de) |
BR (1) | BR0212212A (de) |
CA (1) | CA2458959A1 (de) |
MX (1) | MXPA04001939A (de) |
NO (1) | NO20040875D0 (de) |
WO (1) | WO2003020117A2 (de) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040081704A1 (en) | 1998-02-13 | 2004-04-29 | Centerpulse Biologics Inc. | Implantable putty material |
US20020114795A1 (en) | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
US7132110B2 (en) * | 2001-08-30 | 2006-11-07 | Isotis Orthobiologics, Inc. | Tissue repair compositions and methods for their manufacture and use |
US7166133B2 (en) | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
US7622562B2 (en) | 2002-06-26 | 2009-11-24 | Zimmer Orthobiologics, Inc. | Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue |
US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
WO2005065396A2 (en) | 2003-12-31 | 2005-07-21 | Osteotech, Inc. | Improved bone matrix compositions and methods |
US20070231788A1 (en) * | 2003-12-31 | 2007-10-04 | Keyvan Behnam | Method for In Vitro Assay of Demineralized Bone Matrix |
US20090319045A1 (en) | 2004-10-12 | 2009-12-24 | Truncale Katherine G | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
US7670384B2 (en) * | 2004-10-14 | 2010-03-02 | Biomet Manufacturing Corp. | Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone |
US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
DE102005038381A1 (de) * | 2005-08-13 | 2007-02-15 | Amedo Gmbh | Schwammartiges Implantat |
US20070074980A1 (en) * | 2005-09-02 | 2007-04-05 | Bankoski Brian R | Implant rehydration packages and methods of use |
JP2009508596A (ja) | 2005-09-19 | 2009-03-05 | ヒストジェニックス コーポレイション | 細胞支持基材及びその調製方法 |
US9005646B2 (en) | 2005-10-12 | 2015-04-14 | Lifenet Health | Compositions for repair of defects in tissues, and methods of making the same |
US9132208B2 (en) * | 2008-08-07 | 2015-09-15 | Lifenet Health | Composition for a tissue repair implant and methods of making the same |
CN101365499A (zh) * | 2005-11-01 | 2009-02-11 | 骨骼技术股份有限公司 | 骨基质组合物和方法 |
US7892577B2 (en) * | 2006-02-27 | 2011-02-22 | Globus Medical, Inc. | Bone graft materials derived from mineralized gelatin |
US8784477B2 (en) * | 2011-01-05 | 2014-07-22 | Abbott Cardiovascular Systems Inc. | Stent graft with two layer ePTFE layer system with high plasticity and high rigidity |
US7785634B2 (en) * | 2006-02-27 | 2010-08-31 | Globus Medical, Inc. | Bone graft materials derived from mineralized gelatin |
US7718616B2 (en) | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
US20080233203A1 (en) * | 2007-03-21 | 2008-09-25 | Jennifer Woodell-May | Porous orthapedic materials coated with demineralized bone matrix |
CA3062443C (en) * | 2007-06-15 | 2022-03-15 | Warsaw Orthopedic, Inc. | Method of treating tissue |
US9554920B2 (en) * | 2007-06-15 | 2017-01-31 | Warsaw Orthopedic, Inc. | Bone matrix compositions having nanoscale textured surfaces |
WO2008157492A2 (en) * | 2007-06-15 | 2008-12-24 | Osteotech, Inc. | Osteoinductive demineralized cancellous bone |
US8357384B2 (en) | 2007-06-15 | 2013-01-22 | Warsaw Orthopedic, Inc. | Bone matrix compositions and methods |
US20110054408A1 (en) * | 2007-07-10 | 2011-03-03 | Guobao Wei | Delivery systems, devices, tools, and methods of use |
US9358113B2 (en) * | 2007-07-10 | 2016-06-07 | Warsaw Orthopedic, Inc. | Delivery system |
WO2009052492A2 (en) * | 2007-10-19 | 2009-04-23 | Osteotech, Inc. | Demineralized bone matrix compositions and methods |
WO2009086305A2 (en) * | 2007-12-21 | 2009-07-09 | Rti Biologics, Inc. | Osteoinductive putties and methods of making and using such putties |
US20090192528A1 (en) * | 2008-01-29 | 2009-07-30 | Biomet Biologics, Inc. | Method and device for hernia repair |
US9131944B2 (en) | 2008-01-29 | 2015-09-15 | Ohk Medical Devices Ltd. | Mobile torus devices |
US8366739B2 (en) | 2008-01-30 | 2013-02-05 | Ohk Medical Devices Ltd. | Motion control devices |
CN102105133B (zh) * | 2008-07-21 | 2015-06-17 | 奥德纳米有限公司 | 控制释放型耳结构调节和先天性免疫系统调节组合物以及治疗耳部病症的方法 |
US9192695B2 (en) | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
US9320761B2 (en) | 2008-12-18 | 2016-04-26 | Vivex Biomedical, Inc. | Bone induction system and methods |
US9101475B2 (en) * | 2009-02-12 | 2015-08-11 | Warsaw Orthopedic, Inc. | Segmented delivery system |
US20110070312A1 (en) * | 2009-08-03 | 2011-03-24 | Guobao Wei | Bone matrix compositions and methods |
US20140286911A1 (en) | 2013-03-15 | 2014-09-25 | Allosource | Cell repopulated collagen matrix for soft tissue repair and regeneration |
CN107412864A (zh) | 2009-12-13 | 2017-12-01 | 阿米特·普拉卡什·戈维 | 生物活性移植物和复合物 |
DE102010020412B3 (de) * | 2010-05-12 | 2011-06-01 | Heinz Kurz Gmbh Medizintechnik | Testeinrichtung mit Thermo-Dummy für Gehörknöchelchenprothese mit Formgedächtnis |
EP2640429B1 (de) | 2010-11-15 | 2016-12-21 | Zimmer Orthobiologics, Inc. | Füller für knochenhohlräume |
US8551525B2 (en) | 2010-12-23 | 2013-10-08 | Biostructures, Llc | Bone graft materials and methods |
KR101329559B1 (ko) * | 2011-08-18 | 2013-11-14 | 주식회사 셀루메드 | 골 형성 유도 조성물의 제조 방법 |
WO2013075091A1 (en) | 2011-11-17 | 2013-05-23 | Allosource | Multi-piece machine graft systems and methods |
US10207027B2 (en) | 2012-06-11 | 2019-02-19 | Globus Medical, Inc. | Bioactive bone graft substitutes |
AU2014225458A1 (en) | 2013-03-07 | 2015-07-09 | Allosource | Consistent calcium content bone allograft systems and methods |
US9539286B2 (en) | 2013-10-18 | 2017-01-10 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
US9486483B2 (en) | 2013-10-18 | 2016-11-08 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
US9579421B2 (en) | 2014-02-07 | 2017-02-28 | Globus Medical Inc. | Bone grafts and methods of making and using bone grafts |
US9463264B2 (en) | 2014-02-11 | 2016-10-11 | Globus Medical, Inc. | Bone grafts and methods of making and using bone grafts |
WO2015175983A1 (en) | 2014-05-16 | 2015-11-19 | Allosource | Composite bone constructs and methods |
US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
US10016529B2 (en) | 2015-06-10 | 2018-07-10 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
US11426489B2 (en) | 2015-06-10 | 2022-08-30 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
US11090411B2 (en) | 2016-01-28 | 2021-08-17 | Warsaw Orthopedic, Inc. | Electron beam irradiated osteoinductive bone implant |
EP3645066A1 (de) | 2017-06-30 | 2020-05-06 | Allosource | Zelluläre knochentransplantate, verfahren zur herstellung und verwendung |
AU2018399962A1 (en) | 2018-01-02 | 2020-07-30 | Cartiheal (2009) Ltd. | Implantation tool and protocol for optimized solid substrates promoting cell and tissue growth |
NL2021794B1 (en) | 2018-10-11 | 2020-05-13 | Access2Bone Ip B V | Bioactive bone repair particles |
US11207445B2 (en) * | 2019-07-09 | 2021-12-28 | Community Blood Center | Allograft bone putty and methods of making the same |
CN114364409A (zh) * | 2019-07-10 | 2022-04-15 | 阿克塞斯有限公司 | 增强的成骨组合物 |
WO2021085775A1 (ko) * | 2019-10-30 | 2021-05-06 | 주식회사 엘앤씨바이오 | 골 무기질 성분을 함유하는 복합 탈회골 조성물 및 그 제조공정 |
US11896736B2 (en) | 2020-07-13 | 2024-02-13 | Globus Medical, Inc | Biomaterial implants and methods of making the same |
NL2030793B1 (en) | 2022-01-31 | 2023-08-08 | Access2Bone Ip B V | Malleable bone repair material |
US20230390070A1 (en) * | 2022-06-07 | 2023-12-07 | Warsaw Orthopedic, Inc. | Methods and apparatus for coating bone particles using a mesh |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4394370A (en) * | 1981-09-21 | 1983-07-19 | Jefferies Steven R | Bone graft material for osseous defects and method of making same |
US4440750A (en) * | 1982-02-12 | 1984-04-03 | Collagen Corporation | Osteogenic composition and method |
US4627982A (en) * | 1984-07-16 | 1986-12-09 | Collagen Corporation | Partially purified bone-inducing factor |
US4563350A (en) | 1984-10-24 | 1986-01-07 | Collagen Corporation | Inductive collagen based bone repair preparations |
US4902296A (en) * | 1986-10-29 | 1990-02-20 | The University Of Virginia Alumni Patents Foundation | Use of demineralized bone matrix in the repair of segmental defects |
US5108753A (en) | 1988-04-08 | 1992-04-28 | Creative Biomolecules | Osteogenic devices |
US4971954A (en) * | 1988-11-23 | 1990-11-20 | University Of Medicine And Dentistry Of New Jersey | Collagen-based matrices ribose cross-linked |
US5290558A (en) | 1989-09-21 | 1994-03-01 | Osteotech, Inc. | Flowable demineralized bone powder composition and its use in bone repair |
US5236456A (en) * | 1989-11-09 | 1993-08-17 | Osteotech, Inc. | Osteogenic composition and implant containing same |
US5244577A (en) * | 1990-09-06 | 1993-09-14 | Takeda Chemical Industries, Ltd. | Process for preparing osteogenesis promoting substance |
US5290763A (en) * | 1991-04-22 | 1994-03-01 | Intermedics Orthopedics/Denver, Inc. | Osteoinductive protein mixtures and purification processes |
SE501028C2 (sv) | 1993-03-19 | 1994-10-24 | Ellco Food Ab | Förfarande för framställning av gelatin |
US5531791A (en) | 1993-07-23 | 1996-07-02 | Bioscience Consultants | Composition for repair of defects in osseous tissues, method of making, and prosthesis |
US5516532A (en) | 1994-08-05 | 1996-05-14 | Children's Medical Center Corporation | Injectable non-immunogenic cartilage and bone preparation |
US6180606B1 (en) * | 1994-09-28 | 2001-01-30 | Gensci Orthobiologics, Inc. | Compositions with enhanced osteogenic potential, methods for making the same and uses thereof |
US5707962A (en) * | 1994-09-28 | 1998-01-13 | Gensci Regeneration Sciences Inc. | Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof |
US6189537B1 (en) | 1996-09-06 | 2001-02-20 | Lifenet | Process for producing osteoinductive bone, and osteoinductive bone produced thereby |
US5676146B1 (en) | 1996-09-13 | 2000-04-18 | Osteotech Inc | Surgical implant containing a resorbable radiopaque marker and method of locating such within a body |
ATE239514T1 (de) | 1997-02-07 | 2003-05-15 | Stryker Corp | Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung |
JP5105216B2 (ja) | 1997-02-13 | 2012-12-26 | ジンマー オーソバイオロジックス,インコーポレーテッド | 移植可能なパテ状材料 |
US20020098222A1 (en) | 1997-03-13 | 2002-07-25 | John F. Wironen | Bone paste |
US20020018796A1 (en) | 1998-01-28 | 2002-02-14 | John F. Wironen | Thermally sterilized bone paste |
US20020076429A1 (en) | 1998-01-28 | 2002-06-20 | John F. Wironen | Bone paste subjected to irradiative and thermal treatment |
US6123731A (en) * | 1998-02-06 | 2000-09-26 | Osteotech, Inc. | Osteoimplant and method for its manufacture |
US6030635A (en) | 1998-02-27 | 2000-02-29 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
US6458375B1 (en) | 1998-02-27 | 2002-10-01 | Musculoskeletal Transplant Foundation | Malleable paste with allograft bone reinforcement for filling bone defects |
US7045141B2 (en) | 1998-02-27 | 2006-05-16 | Musculoskeletal Transplant Foundation | Allograft bone composition having a gelatin binder |
US6437018B1 (en) | 1998-02-27 | 2002-08-20 | Musculoskeletal Transplant Foundation | Malleable paste with high molecular weight buffered carrier for filling bone defects |
US6432710B1 (en) | 1998-05-22 | 2002-08-13 | Isolagen Technologies, Inc. | Compositions for regenerating tissue that has deteriorated, and methods for using such compositions |
US6080843A (en) | 1998-11-03 | 2000-06-27 | Eastman Kodak Company | Gelatin and method of manufacture |
US5908921A (en) | 1998-11-03 | 1999-06-01 | Eastman Kodak Company | Method of manufacturing gelatin |
US6599520B2 (en) * | 1999-10-14 | 2003-07-29 | Osteotech, Inc. | Method of inducing new bone growth in porous bone sites |
US6627230B2 (en) * | 2000-12-22 | 2003-09-30 | Centerpulse Biologics Inc. | Method of preparing a bone product by removing cancellous bone matrix |
US7132110B2 (en) * | 2001-08-30 | 2006-11-07 | Isotis Orthobiologics, Inc. | Tissue repair compositions and methods for their manufacture and use |
-
2002
- 2002-07-15 US US10/195,671 patent/US7132110B2/en not_active Expired - Lifetime
- 2002-08-30 EP EP02759522A patent/EP1453434B1/de not_active Expired - Lifetime
- 2002-08-30 WO PCT/US2002/027908 patent/WO2003020117A2/en not_active Application Discontinuation
- 2002-08-30 BR BR0212212-0A patent/BR0212212A/pt not_active IP Right Cessation
- 2002-08-30 AT AT02759522T patent/ATE517646T1/de not_active IP Right Cessation
- 2002-08-30 MX MXPA04001939A patent/MXPA04001939A/es unknown
- 2002-08-30 CA CA002458959A patent/CA2458959A1/en not_active Abandoned
- 2002-08-30 KR KR10-2004-7003098A patent/KR20040048403A/ko not_active Application Discontinuation
-
2004
- 2004-02-27 NO NO20040875A patent/NO20040875D0/no not_active Application Discontinuation
-
2006
- 2006-07-26 US US11/459,972 patent/US7811608B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP1453434A2 (de) | 2004-09-08 |
US20060251729A1 (en) | 2006-11-09 |
CA2458959A1 (en) | 2003-03-13 |
US7811608B2 (en) | 2010-10-12 |
WO2003020117A3 (en) | 2004-07-01 |
NO20040875D0 (no) | 2004-02-27 |
MXPA04001939A (es) | 2005-03-07 |
WO2003020117A2 (en) | 2003-03-13 |
EP1453434B1 (de) | 2011-07-27 |
US7132110B2 (en) | 2006-11-07 |
BR0212212A (pt) | 2005-08-30 |
US20030044445A1 (en) | 2003-03-06 |
KR20040048403A (ko) | 2004-06-09 |
EP1453434A4 (de) | 2008-03-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE517646T1 (de) | Gewebereparaturzusammensetzungen und verfahren für ihre herstellung und verwendung | |
ATE415136T1 (de) | Trockene hämostatische zusammensetzungen und verfahren zu ihrer herstellung | |
ATE327020T1 (de) | Verfahren und apparat zur herstellung von extrakten und ölen aus pflanzen und anderen stoffen | |
HUP9904266A2 (hu) | Eljárás tejsavbaktériumokat tartalmazó szárított élelmiszer-kompozíciók előállítására | |
ATE422524T1 (de) | Verfahren zur herstellung von celluloseetherprodukten mit erhöhter viskosität und feinheit | |
TW200641130A (en) | Production of polyunsaturated fatty acids using novel cell treatment method | |
DE602005027581D1 (de) | Verfahren zur herstellung von regeneriertem tabakmaterial | |
DE60024325D1 (de) | Verfahren zur herstellung eines wasserloeslichen kaffee- oder teeproduktes aus einem nicht wiederbefeuchtetem material erhalten durch trocknung eines extraktes | |
ATE294594T1 (de) | Polynukleotidzusammensetzung, verfahren zu deren herstellung und verwendung | |
ATE275155T1 (de) | Nahrungsmittel auf basis eines sauren proteins unter anwendung von pektinen und verfahren zu dessen herstellung | |
DE50001574D1 (de) | Verfahren zum dehydratisieren von biologischen geweben zur herstellung von transplantat-konserven | |
DK1296569T3 (da) | Fremgangsmåde til fremstilling af væskeformig rög | |
DE69911656D1 (de) | Verfahren zur herstellung eines hydraulischen bindemittels auf der basis von anhydrite iii oder alpha und damit hergestelltes bindemittel | |
WO2005018492A3 (en) | Dura substiture and a process for producing the same | |
DE69624222T2 (de) | Löslicher instantkaffee und verfahren zu dessen herstellung | |
ATE208565T1 (de) | Verfahren zur herstellung eines löslichen kaffeeprodukts | |
CA2400300A1 (en) | Method for producing shredded tobacco and production system for use therein | |
MY129550A (en) | Production process for natural rubber and natural rubber obtained by the same process | |
CN101348531B (zh) | 一种果胶快速分级方法 | |
CN113509517B (zh) | 一种息半夏的产地加工方法 | |
ATE111942T1 (de) | Schneezusammensetzung und verfahren zur herstellung von schnee-ersatz. | |
MY136885A (en) | Film coated tablet | |
KR950026392A (ko) | 백삼박으로부터 식이성 섬유의 제조방법 | |
BG95425A (bg) | Метод за добив на масло от семена на бобови растения | |
DE602004020962D1 (de) | Sojaproteinkonzentrat mit hoher Gelfestigkeit und Verfahren zur Herstellung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |