ATE513032T1 - Aufgereinigte bakterielle minizellen - Google Patents
Aufgereinigte bakterielle minizellenInfo
- Publication number
- ATE513032T1 ATE513032T1 AT08101712T AT08101712T ATE513032T1 AT E513032 T1 ATE513032 T1 AT E513032T1 AT 08101712 T AT08101712 T AT 08101712T AT 08101712 T AT08101712 T AT 08101712T AT E513032 T1 ATE513032 T1 AT E513032T1
- Authority
- AT
- Austria
- Prior art keywords
- minicells
- provides
- minicell preparations
- purified minicell
- parent bacterial
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/02—Separating microorganisms from their culture media
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/602,021 US7611885B2 (en) | 2003-06-24 | 2003-06-24 | Pharmaceutically compatible method for purifying intact bacterial minicells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE513032T1 true ATE513032T1 (de) | 2011-07-15 |
Family
ID=33539477
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04743793T ATE461269T1 (de) | 2003-06-24 | 2004-06-23 | Pharmazeutisch verträgliches verfahren zur reinigung intakter bakterienminizellen |
| AT08101712T ATE513032T1 (de) | 2003-06-24 | 2004-06-23 | Aufgereinigte bakterielle minizellen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04743793T ATE461269T1 (de) | 2003-06-24 | 2004-06-23 | Pharmazeutisch verträgliches verfahren zur reinigung intakter bakterienminizellen |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US7611885B2 (de) |
| EP (3) | EP1636344B1 (de) |
| JP (1) | JP4834544B2 (de) |
| CN (2) | CN1809629B (de) |
| AT (2) | ATE461269T1 (de) |
| AU (2) | AU2004249970B2 (de) |
| CA (2) | CA2530055C (de) |
| CY (1) | CY1118218T1 (de) |
| DE (1) | DE602004026051D1 (de) |
| DK (3) | DK1947171T3 (de) |
| ES (3) | ES2342830T3 (de) |
| HK (3) | HK1089207A1 (de) |
| HU (1) | HUE030642T2 (de) |
| MX (1) | MXPA05013620A (de) |
| NZ (1) | NZ544653A (de) |
| PL (2) | PL1947171T3 (de) |
| PT (2) | PT1947171E (de) |
| SI (1) | SI2333044T1 (de) |
| WO (1) | WO2004113507A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2302063B1 (de) * | 2001-10-15 | 2016-05-04 | EnGeneIC Molecular Delivery Pty Ltd. | Intakte Minizellen als Vektoren für DNA-Transfer und Gentherapie in vitro und in vivo |
| US7611885B2 (en) | 2003-06-24 | 2009-11-03 | Engeneic Molecular Delivery Pty, Ltd. | Pharmaceutically compatible method for purifying intact bacterial minicells |
| CA2549840C (en) | 2003-12-09 | 2012-03-20 | Engeneic Molecular Delivery Pty Ltd. | Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells |
| WO2005079854A1 (en) | 2004-02-02 | 2005-09-01 | Engeneic Molecular Delivery Pty Ltd. | Compositions and methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
| US8772013B2 (en) * | 2004-02-02 | 2014-07-08 | Engeneic Molecular Delivery Pty Ltd | Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
| SI2386640T1 (sl) | 2004-08-26 | 2015-06-30 | Engeneic Molecular Delivery Pty Ltd | Dostava funkcionalnih nukleinskih kislin celicam sesalcev preko bakterijsko izvirajočih, intaktnih minicelic |
| US9878043B2 (en) | 2006-06-23 | 2018-01-30 | Engeneic Molecular Delivery Pty Ltd | Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells |
| DK2865755T3 (en) | 2007-03-30 | 2017-05-15 | Engeneic Molecular Delivery Pty Ltd | BACTERIAL DERIVATIVE INTACT MINICELLS WITH REGULATORY RNA |
| CA2729545C (en) | 2008-06-25 | 2019-07-09 | Vaxiion Therapeutics, Inc. | Regulated genetic suicide mechanism compositions and methods |
| CN102656186A (zh) | 2008-07-17 | 2012-09-05 | 纽崔佩普有限公司 | 治疗剂 |
| JP5816164B2 (ja) | 2009-05-07 | 2015-11-18 | ビオメリュー・インコーポレイテッド | 抗生物質耐性測定方法 |
| US20120142089A1 (en) * | 2010-12-01 | 2012-06-07 | Samsung Electronics Co., Ltd. | Method of separating target cell in biological sample |
| US9624474B2 (en) * | 2010-12-01 | 2017-04-18 | Samsung Electronics Co, Ltd. | Method of separating target cell in biological sample |
| US9844598B2 (en) * | 2011-12-13 | 2017-12-19 | Engeneic Molecular Delivery Pty Ltd | Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors |
| WO2013110120A1 (en) | 2012-01-24 | 2013-08-01 | Inter-K Pty Limited | Peptide agents for cancer therapy |
| KR102433719B1 (ko) | 2013-10-04 | 2022-08-17 | 엔진아이씨 몰레큘러 딜리버리 피티와이 리미티드 | 약물 로딩된, 이중특이성 리간드-표적화된 미니세포 및 인터페론 감마에 의한 복합 종양 치료 |
| EP3200765A4 (de) | 2014-10-03 | 2018-05-30 | EnGeneIC Molecular Delivery Pty Ltd | Verbessertes laden von intakten, bakteriell abgeleiteten vesikeln mit kleinen molekülverbindungen |
| WO2017024059A1 (en) | 2015-08-04 | 2017-02-09 | Vaxiion Therapeutics, Llc | Ionizing irradiation sterilization of bacterial minicell-based biopharmaceuticals and methods of use |
| CN110022905B (zh) | 2016-10-06 | 2024-02-06 | 安吉尼科分子传输公司 | 用于递送核酸佐剂的细菌小细胞和使用其的方法 |
| EP3826654A4 (de) | 2018-07-23 | 2022-07-06 | EnGeneIC Molecular Delivery Pty Ltd | Zusammensetzungen mit aus bakterien abgeleiteten minizellen und verfahren zur verwendung davon |
| WO2021257788A1 (en) * | 2020-06-17 | 2021-12-23 | Flagship Pioneering Innovations Vi, Llc | Methods for manufacturing adas |
| CN113186100B (zh) * | 2021-05-11 | 2022-10-04 | 中国科学院青岛生物能源与过程研究所 | 一种富集污水微生物以用于单细胞精度表型测量和分选的试剂盒及方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4311797A (en) | 1979-09-18 | 1982-01-19 | University Of Saskatchewan | Anucleated live E. coli vaccine |
| CN1375004A (zh) | 1999-04-21 | 2002-10-16 | 惠氏公司 | 抑制多核苷酸序列的功能的方法和组合物 |
| AU2001294520A1 (en) * | 2000-08-21 | 2002-03-04 | Clonex Development, Inc. | Methods and compositions for increasing protein yield from a cell culture |
| WO2002072759A2 (en) | 2001-03-07 | 2002-09-19 | Children's Medical Center Corporation | Method to screen peptide display libraries using minicell display |
| US7011946B2 (en) * | 2001-05-22 | 2006-03-14 | Trustees Of Tufts College | In vivo assay for identification of antimicrobial agents |
| US20030194798A1 (en) | 2001-05-24 | 2003-10-16 | Surber Mark W. | Minicell compositions and methods |
| EP2302063B1 (de) | 2001-10-15 | 2016-05-04 | EnGeneIC Molecular Delivery Pty Ltd. | Intakte Minizellen als Vektoren für DNA-Transfer und Gentherapie in vitro und in vivo |
| CA2517027A1 (en) | 2002-02-25 | 2003-09-04 | Vaxiion Therapeutics, Inc. | Minicell compositions and methods |
| US7611885B2 (en) | 2003-06-24 | 2009-11-03 | Engeneic Molecular Delivery Pty, Ltd. | Pharmaceutically compatible method for purifying intact bacterial minicells |
| CA2549840C (en) | 2003-12-09 | 2012-03-20 | Engeneic Molecular Delivery Pty Ltd. | Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells |
| US8772013B2 (en) | 2004-02-02 | 2014-07-08 | Engeneic Molecular Delivery Pty Ltd | Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
| SI2386640T1 (sl) | 2004-08-26 | 2015-06-30 | Engeneic Molecular Delivery Pty Ltd | Dostava funkcionalnih nukleinskih kislin celicam sesalcev preko bakterijsko izvirajočih, intaktnih minicelic |
| KR100967868B1 (ko) | 2004-12-17 | 2010-07-05 | 베쓰 이스라엘 디코니스 메디칼 센터 | 박테리아 매개 유전자 침묵을 위한 조성물 및 이것을이용하는 방법 |
| US9878043B2 (en) | 2006-06-23 | 2018-01-30 | Engeneic Molecular Delivery Pty Ltd | Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells |
-
2003
- 2003-06-24 US US10/602,021 patent/US7611885B2/en active Active
-
2004
- 2004-06-23 MX MXPA05013620A patent/MXPA05013620A/es active IP Right Grant
- 2004-06-23 SI SI200432358A patent/SI2333044T1/sl unknown
- 2004-06-23 CA CA2530055A patent/CA2530055C/en not_active Expired - Fee Related
- 2004-06-23 EP EP04743793A patent/EP1636344B1/de not_active Expired - Lifetime
- 2004-06-23 CN CN2004800175496A patent/CN1809629B/zh not_active Expired - Lifetime
- 2004-06-23 ES ES04743793T patent/ES2342830T3/es not_active Expired - Lifetime
- 2004-06-23 PL PL08101712T patent/PL1947171T3/pl unknown
- 2004-06-23 PT PT08101712T patent/PT1947171E/pt unknown
- 2004-06-23 DK DK08101712.1T patent/DK1947171T3/da active
- 2004-06-23 AU AU2004249970A patent/AU2004249970B2/en not_active Expired
- 2004-06-23 DE DE602004026051T patent/DE602004026051D1/de not_active Expired - Lifetime
- 2004-06-23 DK DK10180971.3T patent/DK2333044T3/en active
- 2004-06-23 ES ES10180971.3T patent/ES2602572T3/es not_active Expired - Lifetime
- 2004-06-23 JP JP2006516573A patent/JP4834544B2/ja not_active Expired - Lifetime
- 2004-06-23 CA CA2780843A patent/CA2780843C/en not_active Expired - Fee Related
- 2004-06-23 EP EP08101712A patent/EP1947171B1/de not_active Expired - Lifetime
- 2004-06-23 ES ES08101712T patent/ES2367535T3/es not_active Expired - Lifetime
- 2004-06-23 PL PL10180971T patent/PL2333044T3/pl unknown
- 2004-06-23 CN CN201310201614.1A patent/CN103361286B/zh not_active Expired - Lifetime
- 2004-06-23 NZ NZ544653A patent/NZ544653A/en not_active IP Right Cessation
- 2004-06-23 EP EP10180971.3A patent/EP2333044B1/de not_active Expired - Lifetime
- 2004-06-23 AT AT04743793T patent/ATE461269T1/de not_active IP Right Cessation
- 2004-06-23 DK DK04743793.4T patent/DK1636344T3/da active
- 2004-06-23 PT PT101809713T patent/PT2333044T/pt unknown
- 2004-06-23 WO PCT/IB2004/002091 patent/WO2004113507A1/en active Application Filing
- 2004-06-23 HU HUE10180971A patent/HUE030642T2/en unknown
- 2004-06-23 AT AT08101712T patent/ATE513032T1/de active
-
2006
- 2006-09-13 HK HK06110160.7A patent/HK1089207A1/xx not_active IP Right Cessation
-
2007
- 2007-03-27 US US11/691,698 patent/US8003091B2/en not_active Expired - Lifetime
-
2009
- 2009-01-22 HK HK09100680.6A patent/HK1121190A1/xx not_active IP Right Cessation
- 2009-11-24 AU AU2009239519A patent/AU2009239519B2/en not_active Expired
-
2011
- 2011-04-04 US US13/079,079 patent/US8449877B2/en not_active Expired - Lifetime
- 2011-11-18 HK HK11112555.9A patent/HK1158261A1/zh not_active IP Right Cessation
-
2013
- 2013-04-17 US US13/864,972 patent/US10076545B2/en not_active Expired - Lifetime
-
2016
- 2016-11-09 CY CY20161101151T patent/CY1118218T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1118218T1 (el) | Φαρμακευτικα συμβατη μεθοδος για τον καθαρισμο αθικτων βακτηριακων μινι-κυτταρων | |
| Gilbert et al. | Useful proteins from recombinant bacteria | |
| Garon et al. | Structural features of Borrelia burgdorferi—the Lyme disease spirochete: silver staining for nucleic acids | |
| DE60236145D1 (de) | Zellisolierungsverfahren und verwendungen davon | |
| JPS6391093A (ja) | 高分子量ｄｎａの迅速単離方法 | |
| AU6114199A (en) | Isolation method for nucleic acid and apparatus | |
| ATE204907T1 (de) | Verfahren zur extraktion von polyhydroxy- alkanoaten aus diese enthaltenden halophilen bakterien | |
| JP2002515508A (ja) | 核酸の精製方法および装置 | |
| ATE530253T1 (de) | Zusammensetzung, kit und verfahren zur zelltrennung | |
| Brown et al. | Chloroplast RNA populations in dark-grown, light-grown, and greening Euglena gracilis | |
| HUT62311A (en) | Process for separating dna | |
| KR880701110A (ko) | 생물학적 반응 모디파이어 | |
| WO2004048398A1 (ja) | 核酸の濃縮精製方法および装置 | |
| Krusberg et al. | Technique for axenizing nematodes | |
| Allen | Isolation of micronuclear and macronuclear DNA | |
| SHIOMI et al. | Metrizamide isopycnic centrifugation for the isolation of macro-and micronuclei from Paramecium | |
| Kristiansen et al. | Conservation of Active Ribosomes in Acetone‐Treated Cells of Tetrahymena pyriformis | |
| AU2004238088B2 (en) | Cell separation | |
| Scheinman et al. | Reconstitution of a minimal small ribosomal subunit | |
| CN111440722A (zh) | 一种自由流等电聚焦电泳微生物组分离制备的方法及应用 | |
| CN112983367A (zh) | 一种弓形菌在微生物驱油现场试验效果评价中的应用及其方法 | |
| Holmqvist | Disappearence of the intracytoplasmic membranes in Rhodopseudomonas sphaeroides: A quantitative ultrastructural study | |
| Takigami et al. | 2.9 Removal of Pollutants by Mutant Strains of Microorganisms Induced by Ion-Beam Irradiation Fixation of CO2 by Microalgae | |
| DE69012903D1 (de) | Verfahren zur herstellung und reinigung von hepatitis b-impfstoff. | |
| KR970020168A (ko) | 막을 통해 발효 브로쓰로부터 세포를 제거하는 방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1947171 Country of ref document: EP |