ATE513032T1 - Aufgereinigte bakterielle minizellen - Google Patents
Aufgereinigte bakterielle minizellenInfo
- Publication number
- ATE513032T1 ATE513032T1 AT08101712T AT08101712T ATE513032T1 AT E513032 T1 ATE513032 T1 AT E513032T1 AT 08101712 T AT08101712 T AT 08101712T AT 08101712 T AT08101712 T AT 08101712T AT E513032 T1 ATE513032 T1 AT E513032T1
- Authority
- AT
- Austria
- Prior art keywords
- minicells
- provides
- minicell preparations
- purified minicell
- parent bacterial
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/02—Separating microorganisms from their culture media
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/602,021 US7611885B2 (en) | 2003-06-24 | 2003-06-24 | Pharmaceutically compatible method for purifying intact bacterial minicells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE513032T1 true ATE513032T1 (de) | 2011-07-15 |
Family
ID=33539477
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08101712T ATE513032T1 (de) | 2003-06-24 | 2004-06-23 | Aufgereinigte bakterielle minizellen |
| AT04743793T ATE461269T1 (de) | 2003-06-24 | 2004-06-23 | Pharmazeutisch verträgliches verfahren zur reinigung intakter bakterienminizellen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04743793T ATE461269T1 (de) | 2003-06-24 | 2004-06-23 | Pharmazeutisch verträgliches verfahren zur reinigung intakter bakterienminizellen |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US7611885B2 (de) |
| EP (3) | EP2333044B1 (de) |
| JP (1) | JP4834544B2 (de) |
| CN (2) | CN103361286B (de) |
| AT (2) | ATE513032T1 (de) |
| AU (2) | AU2004249970B2 (de) |
| CA (2) | CA2530055C (de) |
| CY (1) | CY1118218T1 (de) |
| DE (1) | DE602004026051D1 (de) |
| DK (3) | DK1636344T3 (de) |
| ES (3) | ES2602572T3 (de) |
| HK (3) | HK1089207A1 (de) |
| HU (1) | HUE030642T2 (de) |
| MX (1) | MXPA05013620A (de) |
| NZ (1) | NZ544653A (de) |
| PL (2) | PL1947171T3 (de) |
| PT (2) | PT1947171E (de) |
| SI (1) | SI2333044T1 (de) |
| WO (1) | WO2004113507A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2380612T3 (es) * | 2001-10-15 | 2012-05-16 | Engeneic Molecular Delivery Pty Ltd. | Minicélulas intactas como vectores para transferencia de ADN y terapia génica in vitro e in vivo |
| US7611885B2 (en) * | 2003-06-24 | 2009-11-03 | Engeneic Molecular Delivery Pty, Ltd. | Pharmaceutically compatible method for purifying intact bacterial minicells |
| DK1694361T3 (da) | 2003-12-09 | 2011-06-06 | Engeneic Molecular Delivery Pty Ltd | Målrettet levering til ikke-phagocytiske pattedyrceller via bakterielt afledte intakte miniceller |
| PL1718338T3 (pl) | 2004-02-02 | 2015-12-31 | Engeneic Molecular Delivery Pty Ltd | Kompozycje oraz sposoby do celowanego dostarczania leku in vitro oraz in vivo do ssaczych komórek poprzez bakteriopochodne nienaruszone minikomórki |
| US8772013B2 (en) * | 2004-02-02 | 2014-07-08 | Engeneic Molecular Delivery Pty Ltd | Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
| DK2386640T3 (en) | 2004-08-26 | 2015-04-27 | Engeneic Molecular Delivery Pty Ltd | The making of functional nucleic acids into mammalian cells via bacterially derived intact minicells |
| PT2040725E (pt) | 2006-06-23 | 2014-04-24 | Engeneic Molecular Delivery Pty Ltd | Distribuição dirigida de fármacos, ácidos nucleicos terapêuticos e ácidos nucleicos funcionais a células de mamífero através de células bacterianas mortas intactas |
| PL2145002T3 (pl) | 2007-03-30 | 2015-06-30 | Engeneic Molecular Delivery Pty Ltd | Nienaruszone minikomórki pochodzenia bakteryjnego, które obejmują funkcjonalny kwas nukleinowy pozbawiony plazmidu do dostarczania in vivo do komórek ssaczych |
| KR20180013993A (ko) | 2008-06-25 | 2018-02-07 | 벡션 테라퓨틱스 엘엘씨 | 조절된 유전자 자살 메커니즘 조성물 및 방법 |
| WO2010006377A1 (en) | 2008-07-17 | 2010-01-21 | Nutripep Pty Limited | Therapeutic agents |
| CN104655840B (zh) | 2009-05-07 | 2018-03-23 | 生物梅里埃有限公司 | 用于抗微生物剂抗性测定的方法 |
| US20120142089A1 (en) * | 2010-12-01 | 2012-06-07 | Samsung Electronics Co., Ltd. | Method of separating target cell in biological sample |
| US9624474B2 (en) * | 2010-12-01 | 2017-04-18 | Samsung Electronics Co, Ltd. | Method of separating target cell in biological sample |
| LT2790668T (lt) | 2011-12-13 | 2020-12-28 | Engeneic Molecular Delivery Pty Ltd. | Iš bakterijų gautos, nepažeistos miniląstelės, skirtos terapinių agentų pristatymui į smegenų navikus |
| CN104271590B (zh) | 2012-01-24 | 2018-06-05 | Inter-K私人有限公司 | 用于癌治疗的肽剂 |
| MX2016004285A (es) | 2013-10-04 | 2016-07-08 | Engeneic Molecular Delivery Pty Ltd | Tratamiento de tumor por combinacion con minicelulas dirigidas a ligando, biespecificas, cargadas con farmacos e interferon-gamma. |
| CN106999444B (zh) | 2014-10-03 | 2023-12-12 | 安吉尼科分子传输公司 | 完整的细菌衍生的囊泡对小分子化合物的增强装载 |
| AU2016301302B2 (en) | 2015-08-04 | 2023-01-12 | Vaxiion Therapeutics, Llc | Ionizing irradiation sterilization of bacterial minicell-based biopharmaceuticals and methods of use |
| AU2017339841A1 (en) | 2016-10-06 | 2019-05-02 | Engeneic Molecular Delivery Pty Ltd | Bacterial minicells for delivering nucleic acid adjuvants and methods of using the same |
| AU2019311380A1 (en) | 2018-07-23 | 2021-02-11 | Engeneic Molecular Delivery Pty Ltd | Compositions comprising bacterially derived minicells and methods of using the same |
| WO2021257788A1 (en) * | 2020-06-17 | 2021-12-23 | Flagship Pioneering Innovations Vi, Llc | Methods for manufacturing adas |
| CN113186100B (zh) * | 2021-05-11 | 2022-10-04 | 中国科学院青岛生物能源与过程研究所 | 一种富集污水微生物以用于单细胞精度表型测量和分选的试剂盒及方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4311797A (en) | 1979-09-18 | 1982-01-19 | University Of Saskatchewan | Anucleated live E. coli vaccine |
| AU781598B2 (en) | 1999-04-21 | 2005-06-02 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for inhibiting the function of polynucleotide sequences |
| WO2002016590A2 (en) * | 2000-08-21 | 2002-02-28 | Clonex Development, Inc. | Methods and compositions for increasing protein yield from a cell culture |
| IL157794A0 (en) | 2001-03-07 | 2004-03-28 | Childrens Medical Center | Method to screen peptide display libraries using minicell display |
| US7011946B2 (en) * | 2001-05-22 | 2006-03-14 | Trustees Of Tufts College | In vivo assay for identification of antimicrobial agents |
| US20030194798A1 (en) * | 2001-05-24 | 2003-10-16 | Surber Mark W. | Minicell compositions and methods |
| ES2380612T3 (es) | 2001-10-15 | 2012-05-16 | Engeneic Molecular Delivery Pty Ltd. | Minicélulas intactas como vectores para transferencia de ADN y terapia génica in vitro e in vivo |
| EP1487965A4 (de) | 2002-02-25 | 2006-11-15 | Mpex Pharmaceuticals Inc | Minizellzusammensetzungen und -verfahren |
| US7611885B2 (en) * | 2003-06-24 | 2009-11-03 | Engeneic Molecular Delivery Pty, Ltd. | Pharmaceutically compatible method for purifying intact bacterial minicells |
| DK1694361T3 (da) | 2003-12-09 | 2011-06-06 | Engeneic Molecular Delivery Pty Ltd | Målrettet levering til ikke-phagocytiske pattedyrceller via bakterielt afledte intakte miniceller |
| US8772013B2 (en) * | 2004-02-02 | 2014-07-08 | Engeneic Molecular Delivery Pty Ltd | Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
| DK2386640T3 (en) * | 2004-08-26 | 2015-04-27 | Engeneic Molecular Delivery Pty Ltd | The making of functional nucleic acids into mammalian cells via bacterially derived intact minicells |
| EP2270136A1 (de) | 2004-12-17 | 2011-01-05 | Beth Israel Deaconess Medical Center | Zusammensetzungen für bakteriell vermitteltes Gen-silencing sowie Verfahren zur Verwendung davon |
| PT2040725E (pt) * | 2006-06-23 | 2014-04-24 | Engeneic Molecular Delivery Pty Ltd | Distribuição dirigida de fármacos, ácidos nucleicos terapêuticos e ácidos nucleicos funcionais a células de mamífero através de células bacterianas mortas intactas |
-
2003
- 2003-06-24 US US10/602,021 patent/US7611885B2/en active Active
-
2004
- 2004-06-23 AT AT08101712T patent/ATE513032T1/de active
- 2004-06-23 MX MXPA05013620A patent/MXPA05013620A/es active IP Right Grant
- 2004-06-23 ES ES10180971.3T patent/ES2602572T3/es not_active Expired - Lifetime
- 2004-06-23 EP EP10180971.3A patent/EP2333044B1/de not_active Expired - Lifetime
- 2004-06-23 HU HUE10180971A patent/HUE030642T2/en unknown
- 2004-06-23 DK DK04743793.4T patent/DK1636344T3/da active
- 2004-06-23 PT PT08101712T patent/PT1947171E/pt unknown
- 2004-06-23 PT PT101809713T patent/PT2333044T/pt unknown
- 2004-06-23 AT AT04743793T patent/ATE461269T1/de not_active IP Right Cessation
- 2004-06-23 SI SI200432358A patent/SI2333044T1/sl unknown
- 2004-06-23 AU AU2004249970A patent/AU2004249970B2/en not_active Expired
- 2004-06-23 EP EP08101712A patent/EP1947171B1/de not_active Expired - Lifetime
- 2004-06-23 EP EP04743793A patent/EP1636344B1/de not_active Expired - Lifetime
- 2004-06-23 CA CA2530055A patent/CA2530055C/en not_active Expired - Fee Related
- 2004-06-23 WO PCT/IB2004/002091 patent/WO2004113507A1/en active Application Filing
- 2004-06-23 ES ES04743793T patent/ES2342830T3/es not_active Expired - Lifetime
- 2004-06-23 NZ NZ544653A patent/NZ544653A/en not_active IP Right Cessation
- 2004-06-23 CN CN201310201614.1A patent/CN103361286B/zh not_active Expired - Lifetime
- 2004-06-23 PL PL08101712T patent/PL1947171T3/pl unknown
- 2004-06-23 CN CN2004800175496A patent/CN1809629B/zh not_active Expired - Lifetime
- 2004-06-23 JP JP2006516573A patent/JP4834544B2/ja not_active Expired - Lifetime
- 2004-06-23 ES ES08101712T patent/ES2367535T3/es not_active Expired - Lifetime
- 2004-06-23 DK DK10180971.3T patent/DK2333044T3/en active
- 2004-06-23 DE DE602004026051T patent/DE602004026051D1/de not_active Expired - Lifetime
- 2004-06-23 CA CA2780843A patent/CA2780843C/en not_active Expired - Fee Related
- 2004-06-23 DK DK08101712.1T patent/DK1947171T3/da active
- 2004-06-23 PL PL10180971T patent/PL2333044T3/pl unknown
-
2006
- 2006-09-13 HK HK06110160.7A patent/HK1089207A1/xx not_active IP Right Cessation
-
2007
- 2007-03-27 US US11/691,698 patent/US8003091B2/en not_active Expired - Lifetime
-
2009
- 2009-01-22 HK HK09100680.6A patent/HK1121190A1/xx not_active IP Right Cessation
- 2009-11-24 AU AU2009239519A patent/AU2009239519B2/en not_active Expired
-
2011
- 2011-04-04 US US13/079,079 patent/US8449877B2/en not_active Expired - Lifetime
- 2011-11-18 HK HK11112555.9A patent/HK1158261A1/zh not_active IP Right Cessation
-
2013
- 2013-04-17 US US13/864,972 patent/US10076545B2/en not_active Expired - Lifetime
-
2016
- 2016-11-09 CY CY20161101151T patent/CY1118218T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1118218T1 (el) | Φαρμακευτικα συμβατη μεθοδος για τον καθαρισμο αθικτων βακτηριακων μινι-κυτταρων | |
| Gorovsky et al. | Isolation of micro-and macronuclei of Tetrahymena pyriformis | |
| Gilbert et al. | Useful proteins from recombinant bacteria | |
| Tanoue | Detection of dissolved protein molecules in oceanic waters | |
| Garon et al. | Structural features of Borrelia burgdorferi—the Lyme disease spirochete: silver staining for nucleic acids | |
| DE60236145D1 (de) | Zellisolierungsverfahren und verwendungen davon | |
| JPS6391093A (ja) | 高分子量ｄｎａの迅速単離方法 | |
| AU6114199A (en) | Isolation method for nucleic acid and apparatus | |
| JP2002515508A (ja) | 核酸の精製方法および装置 | |
| ATE204907T1 (de) | Verfahren zur extraktion von polyhydroxy- alkanoaten aus diese enthaltenden halophilen bakterien | |
| HK1023083A1 (en) | Cell separation composition, kit and method | |
| Brown et al. | Chloroplast RNA populations in dark-grown, light-grown, and greening Euglena gracilis | |
| HUT62311A (en) | Process for separating dna | |
| KR880701110A (ko) | 생물학적 반응 모디파이어 | |
| WO2004048398A1 (ja) | 核酸の濃縮精製方法および装置 | |
| Krusberg et al. | Technique for axenizing nematodes | |
| Allen | Isolation of micronuclear and macronuclear DNA | |
| EP4212878A1 (de) | Verbesserte antikörperherstellung | |
| SHIOMI et al. | Metrizamide isopycnic centrifugation for the isolation of macro-and micronuclei from Paramecium | |
| Kristiansen et al. | Conservation of Active Ribosomes in Acetone‐Treated Cells of Tetrahymena pyriformis | |
| AU2004238088B2 (en) | Cell separation | |
| CN111440722A (zh) | 一种自由流等电聚焦电泳微生物组分离制备的方法及应用 | |
| CN112983367A (zh) | 一种弓形菌在微生物驱油现场试验效果评价中的应用及其方法 | |
| Holmqvist | Disappearence of the intracytoplasmic membranes in Rhodopseudomonas sphaeroides: A quantitative ultrastructural study | |
| Takigami et al. | 2.9 Removal of Pollutants by Mutant Strains of Microorganisms Induced by Ion-Beam Irradiation Fixation of CO2 by Microalgae |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1947171 Country of ref document: EP |