HK1121190A1 - Purified bacterial minicells - Google Patents

Purified bacterial minicells

Info

Publication number
HK1121190A1
HK1121190A1 HK09100680.6A HK09100680A HK1121190A1 HK 1121190 A1 HK1121190 A1 HK 1121190A1 HK 09100680 A HK09100680 A HK 09100680A HK 1121190 A1 HK1121190 A1 HK 1121190A1
Authority
HK
Hong Kong
Prior art keywords
minicells
provides
minicell preparations
purified minicell
parent bacterial
Prior art date
Application number
HK09100680.6A
Other languages
English (en)
Inventor
Himanshu Brahmbhatt
Jennifer Macdiarmid
Original Assignee
Engeneic Molecular Delivery Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Engeneic Molecular Delivery Pty Ltd filed Critical Engeneic Molecular Delivery Pty Ltd
Publication of HK1121190A1 publication Critical patent/HK1121190A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK09100680.6A 2003-06-24 2009-01-22 Purified bacterial minicells HK1121190A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/602,021 US7611885B2 (en) 2003-06-24 2003-06-24 Pharmaceutically compatible method for purifying intact bacterial minicells

Publications (1)

Publication Number Publication Date
HK1121190A1 true HK1121190A1 (en) 2009-04-17

Family

ID=33539477

Family Applications (3)

Application Number Title Priority Date Filing Date
HK06110160.7A HK1089207A1 (en) 2003-06-24 2006-09-13 Pharmaceutically compatible method for purifying intact bacterial minicells
HK09100680.6A HK1121190A1 (en) 2003-06-24 2009-01-22 Purified bacterial minicells
HK11112555.9A HK1158261A1 (zh) 2003-06-24 2011-11-18 用於純化完整細菌微細胞的藥學上相容的方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK06110160.7A HK1089207A1 (en) 2003-06-24 2006-09-13 Pharmaceutically compatible method for purifying intact bacterial minicells

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK11112555.9A HK1158261A1 (zh) 2003-06-24 2011-11-18 用於純化完整細菌微細胞的藥學上相容的方法

Country Status (19)

Country Link
US (4) US7611885B2 (xx)
EP (3) EP2333044B1 (xx)
JP (1) JP4834544B2 (xx)
CN (2) CN103361286B (xx)
AT (2) ATE513032T1 (xx)
AU (2) AU2004249970B2 (xx)
CA (2) CA2530055C (xx)
CY (1) CY1118218T1 (xx)
DE (1) DE602004026051D1 (xx)
DK (3) DK1636344T3 (xx)
ES (3) ES2367535T3 (xx)
HK (3) HK1089207A1 (xx)
HU (1) HUE030642T2 (xx)
MX (1) MXPA05013620A (xx)
NZ (1) NZ544653A (xx)
PL (2) PL1947171T3 (xx)
PT (2) PT1947171E (xx)
SI (1) SI2333044T1 (xx)
WO (1) WO2004113507A1 (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2463631C (en) * 2001-10-15 2012-07-03 Engeneic Gene Therapy Pty Limited Intact minicells as vectors for dna transfer and gene therapy in vitro and in vivo
US7611885B2 (en) * 2003-06-24 2009-11-03 Engeneic Molecular Delivery Pty, Ltd. Pharmaceutically compatible method for purifying intact bacterial minicells
PL1694361T3 (pl) 2003-12-09 2011-08-31 Engeneic Molecular Delivery Pty Ltd Ukierunkowane dostarczanie genów do niefagocytujących komórek ssaczych z zastosowaniem nienaruszonych minikomórek pochodzących od bakterii
CN102028953B (zh) 2004-02-02 2013-10-30 恩杰内克分子递送有限公司 经细菌来源的完整微细胞在体外和体内将药物靶向递送至哺乳动物细胞的组合物和方法
US8772013B2 (en) * 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
ES2535235T3 (es) 2004-08-26 2015-05-07 Engeneic Molecular Delivery Pty Ltd Administración de ácidos nucleicos funcionales a células de mamífero a través de minicélulas intactas obtenidas a partir de bacterias
PL2712618T3 (pl) * 2006-06-23 2017-07-31 Engeneic Molecular Delivery Pty Ltd. Ukierunkowane dostarczanie leków, terapeutycznych kwasów nukleinowych i funkcjonalnych kwasów nukleinowych do komórek ssaczych przez nienaruszone, uśmiercone komórki bakteryjne
CA2933978C (en) 2007-03-30 2018-08-21 Engeneic Molecular Delivery Pty. Ltd. Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells
KR101813824B1 (ko) 2008-06-25 2017-12-29 벡션 테라퓨틱스 엘엘씨 조절된 유전자 자살 메커니즘 조성물 및 방법
EP2454276A4 (en) 2008-07-17 2013-07-10 Inter K Pty Ltd THERAPEUTIC AGENTS
US8609364B2 (en) * 2009-05-07 2013-12-17 bioM{tilde over (e)}rieux, Inc. Methods for antimicrobial resistance determination
US9624474B2 (en) * 2010-12-01 2017-04-18 Samsung Electronics Co, Ltd. Method of separating target cell in biological sample
US20120142089A1 (en) * 2010-12-01 2012-06-07 Samsung Electronics Co., Ltd. Method of separating target cell in biological sample
SG11201403062YA (en) 2011-12-13 2014-07-30 Engeneic Molecular Delivery Pty Ltd Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors
EP2807180B1 (en) 2012-01-24 2018-03-28 InterK Peptide Therapeutics Limited Peptide agents for cancer therapy
MX2016004285A (es) 2013-10-04 2016-07-08 Engeneic Molecular Delivery Pty Ltd Tratamiento de tumor por combinacion con minicelulas dirigidas a ligando, biespecificas, cargadas con farmacos e interferon-gamma.
EP3200765A4 (en) 2014-10-03 2018-05-30 EnGeneIC Molecular Delivery Pty Ltd Enhanced loading of intact, bacterially derived vesicles with small molecule compounds
JP6824960B2 (ja) 2015-08-04 2021-02-03 バキシオン セラピューティクス，リミテッド ライアビリティ カンパニー 細菌由来ミニ細胞型バイオ医薬品の電離放射線照射滅菌およびその使用方法
EP3522935A4 (en) 2016-10-06 2020-05-13 EnGeneIC Molecular Delivery Pty Ltd. BACTERIAL MINICELLS FOR THE DELIVERY OF NUCLEIC ACID ADJUVANTS AND METHODS OF USE THEREOF
JP2021532106A (ja) 2018-07-23 2021-11-25 エンジーンアイシー モレキュラー デリバリー ピーティーワイ リミテッド 細菌由来ミニ細胞を含む組成物およびそれを使用する方法
EP4168025A1 (en) * 2020-06-17 2023-04-26 Flagship Pioneering Innovations VI, LLC Methods for manufacturing adas
CN113186100B (zh) * 2021-05-11 2022-10-04 中国科学院青岛生物能源与过程研究所 一种富集污水微生物以用于单细胞精度表型测量和分选的试剂盒及方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311797A (en) 1979-09-18 1982-01-19 University Of Saskatchewan Anucleated live E. coli vaccine
WO2000063364A2 (en) 1999-04-21 2000-10-26 American Home Products Corporation Methods and compositions for inhibiting the function of polynucleotide sequences
AU2001294520A1 (en) * 2000-08-21 2002-03-04 Clonex Development, Inc. Methods and compositions for increasing protein yield from a cell culture
WO2002072759A2 (en) 2001-03-07 2002-09-19 Children's Medical Center Corporation Method to screen peptide display libraries using minicell display
US7011946B2 (en) * 2001-05-22 2006-03-14 Trustees Of Tufts College In vivo assay for identification of antimicrobial agents
US20030194798A1 (en) 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
CA2463631C (en) 2001-10-15 2012-07-03 Engeneic Gene Therapy Pty Limited Intact minicells as vectors for dna transfer and gene therapy in vitro and in vivo
WO2003072014A2 (en) 2002-02-25 2003-09-04 Mpex Bioscience, Inc. Minicell compositions and methods
US7611885B2 (en) 2003-06-24 2009-11-03 Engeneic Molecular Delivery Pty, Ltd. Pharmaceutically compatible method for purifying intact bacterial minicells
PL1694361T3 (pl) 2003-12-09 2011-08-31 Engeneic Molecular Delivery Pty Ltd Ukierunkowane dostarczanie genów do niefagocytujących komórek ssaczych z zastosowaniem nienaruszonych minikomórek pochodzących od bakterii
US8772013B2 (en) 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
ES2535235T3 (es) 2004-08-26 2015-05-07 Engeneic Molecular Delivery Pty Ltd Administración de ácidos nucleicos funcionales a células de mamífero a través de minicélulas intactas obtenidas a partir de bacterias
WO2006066048A2 (en) 2004-12-17 2006-06-22 Beth Israel Deaconess Medical Center Compositions for bacterial mediated gene silencing and methods of using same
PL2712618T3 (pl) 2006-06-23 2017-07-31 Engeneic Molecular Delivery Pty Ltd. Ukierunkowane dostarczanie leków, terapeutycznych kwasów nukleinowych i funkcjonalnych kwasów nukleinowych do komórek ssaczych przez nienaruszone, uśmiercone komórki bakteryjne

Also Published As

Publication number Publication date
EP1636344A4 (en) 2006-07-19
EP1947171A1 (en) 2008-07-23
DK2333044T3 (en) 2016-12-12
EP2333044B1 (en) 2016-08-17
CA2780843A1 (en) 2012-08-13
CN1809629B (zh) 2013-06-12
US8003091B2 (en) 2011-08-23
PL2333044T3 (pl) 2017-02-28
WO2004113507A9 (en) 2006-08-24
US8449877B2 (en) 2013-05-28
SI2333044T1 (sl) 2016-12-30
AU2009239519A1 (en) 2009-12-10
EP1947171B1 (en) 2011-06-15
ES2602572T3 (es) 2017-02-21
US20070241067A1 (en) 2007-10-18
ATE461269T1 (de) 2010-04-15
US10076545B2 (en) 2018-09-18
CA2530055C (en) 2012-10-02
US7611885B2 (en) 2009-11-03
DK1947171T3 (da) 2011-09-19
HK1089207A1 (en) 2006-11-24
JP2007520201A (ja) 2007-07-26
US20130236422A1 (en) 2013-09-12
CN1809629A (zh) 2006-07-26
EP1636344A1 (en) 2006-03-22
HUE030642T2 (en) 2017-06-28
PT1947171E (pt) 2011-09-07
HK1158261A1 (zh) 2012-07-13
AU2009239519B2 (en) 2010-04-22
PL1947171T3 (pl) 2011-12-30
MXPA05013620A (es) 2006-02-24
CY1118218T1 (el) 2017-06-28
US20040265994A1 (en) 2004-12-30
US20110177185A1 (en) 2011-07-21
AU2004249970B2 (en) 2009-09-10
AU2004249970A1 (en) 2004-12-29
WO2004113507A1 (en) 2004-12-29
NZ544653A (en) 2009-02-28
JP4834544B2 (ja) 2011-12-14
ES2342830T3 (es) 2010-07-15
ATE513032T1 (de) 2011-07-15
CA2530055A1 (en) 2004-12-29
EP2333044A1 (en) 2011-06-15
CN103361286A (zh) 2013-10-23
PT2333044T (pt) 2016-11-21
EP1636344B1 (en) 2010-03-17
ES2367535T3 (es) 2011-11-04
CA2780843C (en) 2013-12-10
CN103361286B (zh) 2016-12-28
DE602004026051D1 (de) 2010-04-29
DK1636344T3 (da) 2010-05-31

Similar Documents

Publication Publication Date Title
HK1121190A1 (en) Purified bacterial minicells
Kikuchi et al. Genetic control of bacteriophage T4 baseplate morphogenesis: II. Mutants unable to form the central part of the baseplate
AU6114199A (en) Isolation method for nucleic acid and apparatus
EP2116609A3 (en) Cell isolation method and uses thereof
JPS6391093A (ja) 高分子量ｄｎａの迅速単離方法
HK1023083A1 (en) Cell separation composition, kit and method
JP2002515508A (ja) 核酸の精製方法および装置
Levy Resistance of minicells to penicillin lysis: a method of obtaining large quantities of purified minicells
WO1994021782A3 (en) Dna isolation method
Brown et al. Chloroplast RNA populations in dark-grown, light-grown, and greening Euglena gracilis
HUT62311A (en) Process for separating dna
WO2004048398A1 (ja) 核酸の濃縮精製方法および装置
Krusberg et al. Technique for axenizing nematodes
Marin et al. Some evidence for the occurrence of ribonucleic acid in the lutoid fraction (lysosomal compartment) from Hevea brasiliensis latex
Allen Isolation of micronuclear and macronuclear DNA
Bauda et al. Plasmid content evaluation of activated sludge
MacFarlane et al. Comparative study of enrichment methods for the isolation of autotrophic nitrifying bacteria from soil, estuarine and marine sediments
Broers et al. An electromigration technique, applied for the concentration of anaerobic protozoa from mass cultures
Holmqvist Disappearence of the intracytoplasmic membranes in Rhodopseudomonas sphaeroides: A quantitative ultrastructural study
Takigami et al. 2.9 Removal of Pollutants by Mutant Strains of Microorganisms Induced by Ion-Beam Irradiation Fixation of CO2 by Microalgae
CN112983367A (zh) 一种弓形菌在微生物驱油现场试验效果评价中的应用及其方法
DE69012903D1 (de) Verfahren zur herstellung und reinigung von hepatitis b-impfstoff.
Sloka Faunistika, dzīvnieku ekoloģija un etoloģija
Brahmachari et al. Preparation of megabase DNA from adult insects and mammalian spleen for pulsed-field gel electrophoresis
Saunders et al. Method and procedure for preparing red blood fractions

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200621