DK1636344T3 - Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller - Google Patents

Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller

Info

Publication number
DK1636344T3
DK1636344T3 DK04743793.4T DK04743793T DK1636344T3 DK 1636344 T3 DK1636344 T3 DK 1636344T3 DK 04743793 T DK04743793 T DK 04743793T DK 1636344 T3 DK1636344 T3 DK 1636344T3
Authority
DK
Denmark
Prior art keywords
minicells
provides
purifying
minicell preparations
purified minicell
Prior art date
Application number
DK04743793.4T
Other languages
English (en)
Inventor
Himanshu Brahmbhatt
Jennifer Macdiarmid
Original Assignee
Engeneic Molecular Delivery Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Engeneic Molecular Delivery Pty Ltd filed Critical Engeneic Molecular Delivery Pty Ltd
Application granted granted Critical
Publication of DK1636344T3 publication Critical patent/DK1636344T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02Separating microorganisms from their culture media
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK04743793.4T 2003-06-24 2004-06-23 Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller DK1636344T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/602,021 US7611885B2 (en) 2003-06-24 2003-06-24 Pharmaceutically compatible method for purifying intact bacterial minicells
PCT/IB2004/002091 WO2004113507A1 (en) 2003-06-24 2004-06-23 Pharmaceutically compatible method for purifying intact bacterial minicells

Publications (1)

Publication Number Publication Date
DK1636344T3 true DK1636344T3 (da) 2010-05-31

Family

ID=33539477

Family Applications (3)

Application Number Title Priority Date Filing Date
DK08101712.1T DK1947171T3 (da) 2003-06-24 2004-06-23 Oprensede bakterieminiceller
DK10180971.3T DK2333044T3 (da) 2003-06-24 2004-06-23 Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller
DK04743793.4T DK1636344T3 (da) 2003-06-24 2004-06-23 Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK08101712.1T DK1947171T3 (da) 2003-06-24 2004-06-23 Oprensede bakterieminiceller
DK10180971.3T DK2333044T3 (da) 2003-06-24 2004-06-23 Farmaceutisk kompatibel fremgangsmåde til oprensning af intakte bakterielle miniceller

Country Status (19)

Country Link
US (4) US7611885B2 (da)
EP (3) EP1636344B1 (da)
JP (1) JP4834544B2 (da)
CN (2) CN1809629B (da)
AT (2) ATE461269T1 (da)
AU (2) AU2004249970B2 (da)
CA (2) CA2530055C (da)
CY (1) CY1118218T1 (da)
DE (1) DE602004026051D1 (da)
DK (3) DK1947171T3 (da)
ES (3) ES2602572T3 (da)
HK (3) HK1089207A1 (da)
HU (1) HUE030642T2 (da)
MX (1) MXPA05013620A (da)
NZ (1) NZ544653A (da)
PL (2) PL1947171T3 (da)
PT (2) PT1947171E (da)
SI (1) SI2333044T1 (da)
WO (1) WO2004113507A1 (da)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1446489B1 (en) * 2001-10-15 2012-01-18 EnGeneIC Molecular Delivery Pty Ltd. Intact minicells as vectors for dna transfer and gene therapy in vitro and in vivo
US7611885B2 (en) * 2003-06-24 2009-11-03 Engeneic Molecular Delivery Pty, Ltd. Pharmaceutically compatible method for purifying intact bacterial minicells
CA2549840C (en) 2003-12-09 2012-03-20 Engeneic Molecular Delivery Pty Ltd. Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells
US8772013B2 (en) * 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
PL1718338T3 (pl) 2004-02-02 2015-12-31 Engeneic Molecular Delivery Pty Ltd Kompozycje oraz sposoby do celowanego dostarczania leku in vitro oraz in vivo do ssaczych komórek poprzez bakteriopochodne nienaruszone minikomórki
NZ553910A (en) 2004-08-26 2009-05-31 Engeneic Molecular Delivery Pty Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells
DK2712618T3 (da) 2006-06-23 2017-01-30 Engeneic Molecular Delivery Pty Ltd Målrettet administration af lægemidler, terapeutiske nukleinsyrer og funktionelle nukleinsyrer til pattedyrceller ved hjælp af intakte dræbte bakterieceller
CA2933978C (en) 2007-03-30 2018-08-21 Engeneic Molecular Delivery Pty. Ltd. Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells
US20100112670A1 (en) 2008-06-25 2010-05-06 Vaxiion Therapeutics, Inc. Regulated genetic suicide mechanism compositions and methods
WO2010006377A1 (en) 2008-07-17 2010-01-21 Nutripep Pty Limited Therapeutic agents
CN104655840B (zh) 2009-05-07 2018-03-23 生物梅里埃有限公司 用于抗微生物剂抗性测定的方法
US20120142089A1 (en) * 2010-12-01 2012-06-07 Samsung Electronics Co., Ltd. Method of separating target cell in biological sample
US9624474B2 (en) * 2010-12-01 2017-04-18 Samsung Electronics Co, Ltd. Method of separating target cell in biological sample
RS61161B1 (sr) 2011-12-13 2021-01-29 Engeneic Molecular Delivery Pty Ltd Intaktne minićelije poreklom iz bakterija za isporuku terapijskih agenasa tumorima mozga
EP2807180B1 (en) 2012-01-24 2018-03-28 InterK Peptide Therapeutics Limited Peptide agents for cancer therapy
JP6538031B2 (ja) 2013-10-04 2019-07-03 エンジーンアイシー モレキュラー デリバリー ピーティーワイ リミテッド 薬物を負荷した二重特異性リガンド標的化ミニ細胞およびインターフェロン−γを用いた併用腫瘍治療
WO2016051389A1 (en) 2014-10-03 2016-04-07 Engeneic Molecular Delivery Pty Ltd Enhanced loading of intact, bacterially derived vesicles with small molecule compounds
CN108348624B (zh) 2015-08-04 2021-07-27 瓦克星治疗有限责任公司 基于细菌小细胞的生物药物的电离辐射灭菌以及使用方法
US11485976B2 (en) 2016-10-06 2022-11-01 Engeneic Molecular Delivery Pty Ltd Bacterial minicells for delivering nucleic acid adjuvants and methods of using the same
SG11202100507PA (en) 2018-07-23 2021-02-25 Engeneic Molecular Delivery Pty Ltd Compositions comprising bacterially derived minicells and methods of using the same
EP4168025A1 (en) * 2020-06-17 2023-04-26 Flagship Pioneering Innovations VI, LLC Methods for manufacturing adas
CN113186100B (zh) * 2021-05-11 2022-10-04 中国科学院青岛生物能源与过程研究所 一种富集污水微生物以用于单细胞精度表型测量和分选的试剂盒及方法

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Publication number Priority date Publication date Assignee Title
US4311797A (en) 1979-09-18 1982-01-19 University Of Saskatchewan Anucleated live E. coli vaccine
KR20010112944A (ko) 1999-04-21 2001-12-22 이곤 이 버그 폴리뉴클레오티드 서열의 기능을 억제하기 위한 방법 및조성물
US6635448B2 (en) * 2000-08-21 2003-10-21 Clonexdevelopment, Inc. Methods and compositions for increasing protein yield from a cell culture
EP1372721A4 (en) * 2001-03-07 2008-04-02 Childrens Medical Center METHOD FOR SCREENING PEPTIDE DISPLAY LIBRARIES WITH A MINIMUM DISPLAY
US7011946B2 (en) * 2001-05-22 2006-03-14 Trustees Of Tufts College In vivo assay for identification of antimicrobial agents
US20030194798A1 (en) * 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
EP1446489B1 (en) 2001-10-15 2012-01-18 EnGeneIC Molecular Delivery Pty Ltd. Intact minicells as vectors for dna transfer and gene therapy in vitro and in vivo
EP2390308A1 (en) 2002-02-25 2011-11-30 Vaxiion Therapeutics Inc Minicell compositions and methods
US7611885B2 (en) * 2003-06-24 2009-11-03 Engeneic Molecular Delivery Pty, Ltd. Pharmaceutically compatible method for purifying intact bacterial minicells
CA2549840C (en) 2003-12-09 2012-03-20 Engeneic Molecular Delivery Pty Ltd. Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells
US8772013B2 (en) * 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
NZ553910A (en) * 2004-08-26 2009-05-31 Engeneic Molecular Delivery Pty Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells
JP5601756B2 (ja) 2004-12-17 2014-10-08 ベス イスラエル デアコネス メディカル センター, インコーポレイテッド 細菌によって媒介される遺伝子サイレンシングのための組成物およびその使用方法
DK2712618T3 (da) * 2006-06-23 2017-01-30 Engeneic Molecular Delivery Pty Ltd Målrettet administration af lægemidler, terapeutiske nukleinsyrer og funktionelle nukleinsyrer til pattedyrceller ved hjælp af intakte dræbte bakterieceller

Also Published As

Publication number Publication date
PL1947171T3 (pl) 2011-12-30
WO2004113507A9 (en) 2006-08-24
EP2333044A1 (en) 2011-06-15
EP1636344A1 (en) 2006-03-22
HUE030642T2 (en) 2017-06-28
US7611885B2 (en) 2009-11-03
NZ544653A (en) 2009-02-28
PL2333044T3 (pl) 2017-02-28
CA2780843C (en) 2013-12-10
DK1947171T3 (da) 2011-09-19
US20040265994A1 (en) 2004-12-30
AU2009239519B2 (en) 2010-04-22
CA2530055C (en) 2012-10-02
JP4834544B2 (ja) 2011-12-14
ES2367535T3 (es) 2011-11-04
JP2007520201A (ja) 2007-07-26
CN1809629A (zh) 2006-07-26
HK1089207A1 (en) 2006-11-24
US10076545B2 (en) 2018-09-18
CN103361286B (zh) 2016-12-28
EP1636344A4 (en) 2006-07-19
EP1947171A1 (en) 2008-07-23
US8449877B2 (en) 2013-05-28
CA2530055A1 (en) 2004-12-29
SI2333044T1 (sl) 2016-12-30
CA2780843A1 (en) 2012-08-13
DE602004026051D1 (de) 2010-04-29
US20130236422A1 (en) 2013-09-12
HK1121190A1 (en) 2009-04-17
CN103361286A (zh) 2013-10-23
US8003091B2 (en) 2011-08-23
CN1809629B (zh) 2013-06-12
ES2602572T3 (es) 2017-02-21
AU2004249970A1 (en) 2004-12-29
WO2004113507A1 (en) 2004-12-29
DK2333044T3 (da) 2016-12-12
PT1947171E (pt) 2011-09-07
AU2009239519A1 (en) 2009-12-10
EP1947171B1 (en) 2011-06-15
ES2342830T3 (es) 2010-07-15
AU2004249970B2 (en) 2009-09-10
HK1158261A1 (zh) 2012-07-13
PT2333044T (pt) 2016-11-21
EP2333044B1 (en) 2016-08-17
US20070241067A1 (en) 2007-10-18
US20110177185A1 (en) 2011-07-21
MXPA05013620A (es) 2006-02-24
CY1118218T1 (el) 2017-06-28
ATE461269T1 (de) 2010-04-15
EP1636344B1 (en) 2010-03-17
ATE513032T1 (de) 2011-07-15

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