ATE504592T1 - Trehaloseverbindung und arzneimittel mit der verbindung - Google Patents
Trehaloseverbindung und arzneimittel mit der verbindungInfo
- Publication number
- ATE504592T1 ATE504592T1 AT07739277T AT07739277T ATE504592T1 AT E504592 T1 ATE504592 T1 AT E504592T1 AT 07739277 T AT07739277 T AT 07739277T AT 07739277 T AT07739277 T AT 07739277T AT E504592 T1 ATE504592 T1 AT E504592T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- trehalose
- present
- drugs containing
- independently represent
- Prior art date
Links
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 title abstract 4
- -1 TREHALOSE COMPOUND Chemical class 0.000 title abstract 4
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 102000008161 Adenosine A3 Receptor Human genes 0.000 abstract 2
- 108010060261 Adenosine A3 Receptor Proteins 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006085245 | 2006-03-27 | ||
| PCT/JP2007/055834 WO2007111214A1 (ja) | 2006-03-27 | 2007-03-22 | トレハロース化合物および該化合物を含有する医薬 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE504592T1 true ATE504592T1 (de) | 2011-04-15 |
Family
ID=38541134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07739277T ATE504592T1 (de) | 2006-03-27 | 2007-03-22 | Trehaloseverbindung und arzneimittel mit der verbindung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8163713B2 (de) |
| EP (1) | EP2000473B1 (de) |
| JP (1) | JP5114627B2 (de) |
| KR (1) | KR101412082B1 (de) |
| CN (1) | CN101443344B (de) |
| AT (1) | ATE504592T1 (de) |
| DE (1) | DE602007013730D1 (de) |
| DK (1) | DK2000473T3 (de) |
| ES (1) | ES2362940T3 (de) |
| PT (1) | PT2000473E (de) |
| TW (1) | TWI382989B (de) |
| WO (1) | WO2007111214A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100093993A1 (en) * | 2007-01-31 | 2010-04-15 | Otsuka Chemical Co., Ltd. | Trehalose compound, process for production of the compound, and immuno-stimulative agent comprising the compound |
| JP5552056B2 (ja) * | 2008-10-31 | 2014-07-16 | 株式会社糖鎖工学研究所 | トレハロース化合物、その製造方法、及び該化合物を含有する医薬 |
| WO2012122338A1 (en) * | 2011-03-08 | 2012-09-13 | Abbott Laboratories | Process for the preparation of 1,2,4-oxadiazol-3-yl derivatives of carboxylic acid |
| WO2012147705A1 (ja) * | 2011-04-24 | 2012-11-01 | 株式会社ネクスト２１ | トレハロースを含有する炎症性呼吸器疾患の治療剤 |
| AU2014264228A1 (en) | 2013-05-07 | 2015-11-12 | Bio Blast Pharma Ltd. | Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose |
| US9084720B2 (en) | 2013-05-07 | 2015-07-21 | BioBlast Pharma Ltd. | Compositions and methods for treating oculopharyngeal muscular dystrophy |
| US12064480B2 (en) | 2018-04-13 | 2024-08-20 | Glaxosmithkline Biologicals Sa | Immunigenic alpha-branched trehalose-diesters |
| US12503482B2 (en) * | 2019-01-08 | 2025-12-23 | The Brigham And Women's Hospital, Inc. | Compositions and methods for trehalose phospholipids |
| CN114929237A (zh) | 2019-10-01 | 2022-08-19 | 西洛斯治疗有限公司 | 海藻糖制剂及其用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5006514A (en) * | 1986-03-20 | 1991-04-09 | Sawai Pharmaceutical Co., Ltd. | α,α-trehalose trimycolates and pharmaceutical compositions |
| US5049664A (en) | 1988-08-26 | 1991-09-17 | Sawai Pharmaceutical Co., Ltd. | Trehalose derivatives |
| US6911526B2 (en) * | 1996-07-22 | 2005-06-28 | The Trustees Of Columbia University In The City Of New York | Compounds that inhibit the interaction between signal-transducing proteins and the GLGF (PDZ/DHR) domain and uses thereof |
| JPH11158073A (ja) | 1997-09-26 | 1999-06-15 | Takeda Chem Ind Ltd | アデノシンａ３拮抗剤 |
| JPH11171727A (ja) * | 1997-09-30 | 1999-06-29 | Kanebo Ltd | 身体洗浄剤組成物 |
| US6352722B1 (en) | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
| US6686366B1 (en) * | 1998-06-02 | 2004-02-03 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
| KR100840727B1 (ko) | 1999-12-02 | 2008-06-23 | 오에스아이 파마슈티컬스, 인코포레이티드 | 아데노신 ａ1, ａ2ａ 및 ａ3 수용체 특이 화합물 및 그의 사용방법 |
| EP1469864A1 (de) * | 2002-01-25 | 2004-10-27 | Muscagen Limited | Verbindungen verwendbar als adenosin-a3-rezeptor-agoniste |
| US7414036B2 (en) | 2002-01-25 | 2008-08-19 | Muscagen Limited | Compounds useful as A3 adenosine receptor agonists |
| US20050010551A1 (en) * | 2003-06-27 | 2005-01-13 | Mcgeachie John S. | Method of and system for determining connections between parties using private links |
-
2007
- 2007-03-22 AT AT07739277T patent/ATE504592T1/de active
- 2007-03-22 US US12/294,800 patent/US8163713B2/en not_active Expired - Fee Related
- 2007-03-22 KR KR1020087025278A patent/KR101412082B1/ko not_active Expired - Fee Related
- 2007-03-22 WO PCT/JP2007/055834 patent/WO2007111214A1/ja not_active Ceased
- 2007-03-22 JP JP2008507454A patent/JP5114627B2/ja not_active Expired - Fee Related
- 2007-03-22 DE DE602007013730T patent/DE602007013730D1/de active Active
- 2007-03-22 EP EP07739277A patent/EP2000473B1/de not_active Not-in-force
- 2007-03-22 DK DK07739277.7T patent/DK2000473T3/da active
- 2007-03-22 ES ES07739277T patent/ES2362940T3/es active Active
- 2007-03-22 PT PT07739277T patent/PT2000473E/pt unknown
- 2007-03-22 CN CN2007800110584A patent/CN101443344B/zh not_active Expired - Fee Related
- 2007-03-26 TW TW096110341A patent/TWI382989B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2362940T3 (es) | 2011-07-15 |
| CN101443344B (zh) | 2012-08-29 |
| EP2000473A4 (de) | 2009-03-11 |
| US8163713B2 (en) | 2012-04-24 |
| DK2000473T3 (da) | 2011-05-16 |
| KR101412082B1 (ko) | 2014-06-26 |
| WO2007111214A1 (ja) | 2007-10-04 |
| PT2000473E (pt) | 2011-07-01 |
| JPWO2007111214A1 (ja) | 2009-08-13 |
| DE602007013730D1 (de) | 2011-05-19 |
| TWI382989B (zh) | 2013-01-21 |
| KR20080103603A (ko) | 2008-11-27 |
| JP5114627B2 (ja) | 2013-01-09 |
| TW200745153A (en) | 2007-12-16 |
| EP2000473A9 (de) | 2009-03-25 |
| EP2000473B1 (de) | 2011-04-06 |
| CN101443344A (zh) | 2009-05-27 |
| EP2000473A2 (de) | 2008-12-10 |
| US20100249057A1 (en) | 2010-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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