ATE503687T1 - Verfahren zur herstellung von formulierungen für inhaliergeräte mit abgemessener dosis - Google Patents
Verfahren zur herstellung von formulierungen für inhaliergeräte mit abgemessener dosisInfo
- Publication number
- ATE503687T1 ATE503687T1 AT07119781T AT07119781T ATE503687T1 AT E503687 T1 ATE503687 T1 AT E503687T1 AT 07119781 T AT07119781 T AT 07119781T AT 07119781 T AT07119781 T AT 07119781T AT E503687 T1 ATE503687 T1 AT E503687T1
- Authority
- AT
- Austria
- Prior art keywords
- dose inhaler
- metered dose
- container
- suspension
- solution
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 229940071648 metered dose inhaler Drugs 0.000 abstract 6
- 239000000725 suspension Substances 0.000 abstract 4
- 229960002744 mometasone furoate Drugs 0.000 abstract 2
- WOFMFGQZHJDGCX-ZULDAHANSA-N mometasone furoate Chemical compound O([C@]1([C@@]2(C)C[C@H](O)[C@]3(Cl)[C@@]4(C)C=CC(=O)C=C4CC[C@H]3[C@@H]2C[C@H]1C)C(=O)CCl)C(=O)C1=CC=CO1 WOFMFGQZHJDGCX-ZULDAHANSA-N 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
- 238000007789 sealing Methods 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
- B65B31/003—Adding propellants in fluid form to aerosol containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Mechanical Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40612702P | 2002-08-27 | 2002-08-27 | |
| US42243602P | 2002-10-30 | 2002-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE503687T1 true ATE503687T1 (de) | 2011-04-15 |
Family
ID=31981380
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07119781T ATE503687T1 (de) | 2002-08-27 | 2003-08-26 | Verfahren zur herstellung von formulierungen für inhaliergeräte mit abgemessener dosis |
| AT03791745T ATE384001T1 (de) | 2002-08-27 | 2003-08-26 | Verfahren zur herstellung von dosierinhalatorformulierungen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03791745T ATE384001T1 (de) | 2002-08-27 | 2003-08-26 | Verfahren zur herstellung von dosierinhalatorformulierungen |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20040042973A1 (enExample) |
| EP (2) | EP1542904B1 (enExample) |
| JP (3) | JP4679901B2 (enExample) |
| AT (2) | ATE503687T1 (enExample) |
| AU (1) | AU2003265639A1 (enExample) |
| CA (1) | CA2495875C (enExample) |
| CY (1) | CY1107376T1 (enExample) |
| DE (2) | DE60318727T2 (enExample) |
| DK (1) | DK1542904T3 (enExample) |
| ES (1) | ES2297262T3 (enExample) |
| MX (1) | MXPA05002248A (enExample) |
| PT (1) | PT1542904E (enExample) |
| SI (1) | SI1542904T1 (enExample) |
| WO (1) | WO2004020289A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0207906D0 (en) | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and mometasone aerosol formulations |
| ES2388537T3 (es) * | 2002-08-23 | 2012-10-16 | Merck Sharp & Dohme Corp. | Inhalador dosificador que contiene una formulación en suspensión de aerosol |
| JP2007509147A (ja) * | 2003-10-20 | 2007-04-12 | シェーリング コーポレイション | 薬学的エアロゾル組成物 |
| SE0401408D0 (sv) * | 2004-06-02 | 2004-06-02 | Astrazeneca Ab | Diameter measuring device |
| WO2006040598A2 (en) * | 2004-10-12 | 2006-04-20 | Generics (Uk) Limited | Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister |
| US20070099883A1 (en) * | 2005-10-07 | 2007-05-03 | Cheryl Lynn Calis | Anhydrous mometasone furoate formulation |
| EP2083798A1 (en) * | 2006-10-19 | 2009-08-05 | Cipla Limited | Pharmaceutical compositions and nasal spray incorporating anhydrous mometasone furoate |
| KR20100004993A (ko) | 2007-02-09 | 2010-01-13 | 쉐링 코포레이션 | 안정한 약제학적 약물 에어로졸 |
| US20080253970A1 (en) * | 2007-02-09 | 2008-10-16 | Schering Corporation | Stable Pharmaceutical Drug Products |
| DK2429510T3 (en) | 2009-05-12 | 2015-09-28 | Galenica Ab | The oil-in-water emulsion mometasone and propylene glycol |
| PL2429490T3 (pl) * | 2009-05-12 | 2017-06-30 | Galenica Ab | Emulsja mometazonu typu olej-w-wodzie |
| MX2012008906A (es) * | 2010-02-10 | 2012-08-15 | Astrazeneca Uk Ltd | Proceso para proporcionar un cartucho relleno para un inhalador. |
| AU2015200276B2 (en) * | 2010-02-10 | 2016-01-21 | Astrazeneca Uk Limited | A filled canister for an inhaler |
| CN107626019A (zh) * | 2016-07-18 | 2018-01-26 | 卓效医疗有限公司 | 手持式喷雾器 |
| CN107951893B (zh) * | 2016-10-18 | 2022-04-26 | 天津金耀集团有限公司 | 一种糠酸莫米松粉吸入剂组合物 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3592319A (en) * | 1968-10-28 | 1971-07-13 | Roy S Rousseau | Article feed control |
| US3835898A (en) * | 1972-11-13 | 1974-09-17 | Kartridg Pak Co | Remotely adjustable filling head |
| US4793461A (en) * | 1987-02-26 | 1988-12-27 | The Kartridg Pak Co. | Container feed apparatus |
| US5143260A (en) * | 1990-06-05 | 1992-09-01 | Nozone Dispenser Systems, Inc. | Aerosol adapter clamp and power system |
| US5182097A (en) * | 1991-02-14 | 1993-01-26 | Virginia Commonwealth University | Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content |
| PT656206E (pt) * | 1991-06-10 | 2001-11-30 | Schering Corp | Formulacoes de aerossois sem clorofluorocarbonetos |
| US6503482B1 (en) * | 1991-06-10 | 2003-01-07 | Schering Corporation | Non-chlorofluorocarbon aerosol formulations |
| US5275212A (en) * | 1993-02-24 | 1994-01-04 | Minnesota Mining And Manufacturing Company | Aerosol filling method |
| GB9612297D0 (en) * | 1996-06-11 | 1996-08-14 | Minnesota Mining & Mfg | Medicinal aerosol formulations |
| US5698161A (en) | 1996-08-26 | 1997-12-16 | Michigan Critical Care Consultants, Inc. | Hollow, multi-dimensional array membrane |
| CO4900027A1 (es) * | 1996-08-29 | 2000-03-27 | Schering Corp | Formulaciones en aerosol de furoato de mometasona sin cloro- fluorocarburos . |
| US6068832A (en) * | 1996-08-29 | 2000-05-30 | Schering Corporation | Chlorofluorocarbon-free mometasone furoate aerosol formulations |
| US20060165606A1 (en) * | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6004537A (en) * | 1998-12-18 | 1999-12-21 | Baker Norton Pharmaceuticals, Inc. | Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol |
| GB9904919D0 (en) * | 1999-03-03 | 1999-04-28 | Novartis Ag | Organic compounds |
| US20030032632A1 (en) * | 1999-12-24 | 2003-02-13 | Crispps Leslie Alan | Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate |
| AU2001278115A1 (en) * | 2000-08-04 | 2002-02-18 | Longwood Pharmaceutical Research, Inc. | Formulations of mometasone and a bronchodilator for pulmonary administration |
| ITMI20010428A1 (it) * | 2001-03-02 | 2002-09-02 | Chemo Breath S A | Composizioni ad uso inalatorio a base di formoterolo |
| AR036358A1 (es) * | 2001-08-28 | 2004-09-01 | Schering Corp | Un inhalador de dosis medidas que contiene una formulacion de suspension en aerosol para inhalacion, un proceso para la produccion de la formulacion, el producto y el uso de una formulacion para la manufactura de un medicamento de asma |
| GB0207906D0 (en) * | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and mometasone aerosol formulations |
| ES2388537T3 (es) * | 2002-08-23 | 2012-10-16 | Merck Sharp & Dohme Corp. | Inhalador dosificador que contiene una formulación en suspensión de aerosol |
| JP2007509147A (ja) * | 2003-10-20 | 2007-04-12 | シェーリング コーポレイション | 薬学的エアロゾル組成物 |
| CA2641616A1 (en) * | 2006-02-09 | 2007-08-23 | Schering Corporation | Pharmaceutical formulations |
| US20080253970A1 (en) * | 2007-02-09 | 2008-10-16 | Schering Corporation | Stable Pharmaceutical Drug Products |
-
2003
- 2003-08-26 SI SI200331133T patent/SI1542904T1/sl unknown
- 2003-08-26 AU AU2003265639A patent/AU2003265639A1/en not_active Abandoned
- 2003-08-26 PT PT03791745T patent/PT1542904E/pt unknown
- 2003-08-26 EP EP03791745A patent/EP1542904B1/en not_active Expired - Lifetime
- 2003-08-26 CA CA2495875A patent/CA2495875C/en not_active Expired - Fee Related
- 2003-08-26 ES ES03791745T patent/ES2297262T3/es not_active Expired - Lifetime
- 2003-08-26 JP JP2004532972A patent/JP4679901B2/ja not_active Expired - Fee Related
- 2003-08-26 MX MXPA05002248A patent/MXPA05002248A/es active IP Right Grant
- 2003-08-26 AT AT07119781T patent/ATE503687T1/de not_active IP Right Cessation
- 2003-08-26 DE DE60318727T patent/DE60318727T2/de not_active Expired - Lifetime
- 2003-08-26 WO PCT/US2003/026512 patent/WO2004020289A1/en not_active Ceased
- 2003-08-26 DE DE60336602T patent/DE60336602D1/de not_active Expired - Lifetime
- 2003-08-26 EP EP07119781A patent/EP1878664B1/en not_active Expired - Lifetime
- 2003-08-26 DK DK03791745T patent/DK1542904T3/da active
- 2003-08-26 AT AT03791745T patent/ATE384001T1/de active
- 2003-08-27 US US10/649,398 patent/US20040042973A1/en not_active Abandoned
-
2006
- 2006-08-18 JP JP2006223635A patent/JP2006305390A/ja active Pending
-
2007
- 2007-11-30 US US11/948,688 patent/US20080066744A1/en not_active Abandoned
-
2008
- 2008-03-31 CY CY20081100362T patent/CY1107376T1/el unknown
-
2010
- 2010-10-08 JP JP2010229135A patent/JP2011046726A/ja not_active Withdrawn
-
2012
- 2012-08-23 US US13/592,899 patent/US20130068218A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1878664B1 (en) | 2011-03-30 |
| EP1542904B1 (en) | 2008-01-16 |
| ATE384001T1 (de) | 2008-02-15 |
| JP2011046726A (ja) | 2011-03-10 |
| DE60318727T2 (de) | 2009-01-08 |
| DE60318727D1 (de) | 2008-03-06 |
| US20040042973A1 (en) | 2004-03-04 |
| DE60336602D1 (de) | 2011-05-12 |
| WO2004020289A1 (en) | 2004-03-11 |
| AU2003265639A1 (en) | 2004-03-19 |
| PT1542904E (pt) | 2008-03-24 |
| CA2495875A1 (en) | 2004-03-11 |
| US20130068218A1 (en) | 2013-03-21 |
| CY1107376T1 (el) | 2012-12-19 |
| JP2005537095A (ja) | 2005-12-08 |
| EP1542904A1 (en) | 2005-06-22 |
| MXPA05002248A (es) | 2005-06-08 |
| JP2006305390A (ja) | 2006-11-09 |
| CA2495875C (en) | 2010-06-22 |
| EP1878664A1 (en) | 2008-01-16 |
| SI1542904T1 (sl) | 2008-06-30 |
| DK1542904T3 (da) | 2008-04-21 |
| US20080066744A1 (en) | 2008-03-20 |
| JP4679901B2 (ja) | 2011-05-11 |
| ES2297262T3 (es) | 2008-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |