ATE492650T1 - Verfahren und vorrichtung zur detektion von markierungselementen in einer probe - Google Patents

Verfahren und vorrichtung zur detektion von markierungselementen in einer probe

Info

Publication number
ATE492650T1
ATE492650T1 AT05784796T AT05784796T ATE492650T1 AT E492650 T1 ATE492650 T1 AT E492650T1 AT 05784796 T AT05784796 T AT 05784796T AT 05784796 T AT05784796 T AT 05784796T AT E492650 T1 ATE492650 T1 AT E492650T1
Authority
AT
Austria
Prior art keywords
sample
detection
location
spot
scanning
Prior art date
Application number
AT05784796T
Other languages
English (en)
Inventor
Reinhold Wimberger-Friedl
Marcello Balistreri
Hendrik Stapert
Original Assignee
Koninkl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv filed Critical Koninkl Philips Electronics Nv
Application granted granted Critical
Publication of ATE492650T1 publication Critical patent/ATE492650T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT05784796T 2004-10-01 2005-09-26 Verfahren und vorrichtung zur detektion von markierungselementen in einer probe ATE492650T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04104834 2004-10-01
PCT/IB2005/053168 WO2006038149A1 (en) 2004-10-01 2005-09-26 Method and apparatus for the detection of labeling elements in a sample

Publications (1)

Publication Number Publication Date
ATE492650T1 true ATE492650T1 (de) 2011-01-15

Family

ID=35355235

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05784796T ATE492650T1 (de) 2004-10-01 2005-09-26 Verfahren und vorrichtung zur detektion von markierungselementen in einer probe

Country Status (7)

Country Link
US (1) US20070254376A1 (de)
EP (1) EP1797195B1 (de)
JP (1) JP2008514950A (de)
CN (1) CN101031660B (de)
AT (1) ATE492650T1 (de)
DE (1) DE602005025508D1 (de)
WO (1) WO2006038149A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE412170T1 (de) * 2004-12-17 2008-11-15 Koninkl Philips Electronics Nv Mehrpunktuntersuchungsgerät
WO2008010120A2 (en) * 2006-07-17 2008-01-24 Koninklijke Philips Electronics N.V. Employing beam scanning for optical detection
WO2008012724A2 (en) * 2006-07-20 2008-01-31 Koninklijke Philips Electronics N.V. Optical tracking and position determination for detection methods and systems
EP2171431B1 (de) 2007-06-28 2017-09-13 Koninklijke Philips N.V. Mikroelektronische sensorvorrichtung für optische untersuchungen auf einer angefeuchteten oberfläche
ATE446500T1 (de) * 2007-09-10 2009-11-15 Hoffmann La Roche Verfahren und vorrichtung zum auswerten eines trockenchemischen testelementes
WO2009115108A1 (en) * 2008-03-19 2009-09-24 Ruprecht-Karls-Universität Heidelberg A method and an apparatus for localization of single dye molecules in the fluorescent microscopy
EP2198965A1 (de) 2008-12-19 2010-06-23 Koninklijke Philips Electronics N.V. Integrierte Vorrichtung zur automatisierten gleichzeitigen Erfassung mehrerer spezifischer Ziele unter Verwendung von Nukleinsäurenamplifikation
KR101178055B1 (ko) 2009-08-14 2012-08-29 제주대학교 산학협력단 높이차 측정 장치 및 방법
WO2012059786A1 (en) * 2010-11-03 2012-05-10 Reametrix Inc. Measurement system for fluorescent detection, and method therefor
WO2013031643A1 (ja) * 2011-08-30 2013-03-07 オリンパス株式会社 膵液を含む生体試料中の標的粒子の検出方法
JP6313978B2 (ja) * 2014-01-08 2018-04-18 オリンパス株式会社 表示方法
KR20170094419A (ko) * 2014-12-15 2017-08-17 메르크 파텐트 게엠베하 편광 광 방출 디바이스
US10156568B2 (en) 2015-04-30 2018-12-18 International Business Machines Corporation Immunoassay for detection of virus-antibody nanocomplexes in solution by chip-based pillar array
CN108982463B (zh) * 2018-09-20 2023-10-03 韩山师范学院 一种用于固体表面荧光检测仪器及其检测方法
WO2021016795A1 (en) 2019-07-29 2021-02-04 Shenzhen Xpectvision Technology Co., Ltd. Biological imaging method using x-ray fluorescence

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US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5547839A (en) * 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US6327031B1 (en) * 1998-09-18 2001-12-04 Burstein Technologies, Inc. Apparatus and semi-reflective optical system for carrying out analysis of samples
GB9418981D0 (en) * 1994-09-21 1994-11-09 Univ Glasgow Apparatus and method for carrying out analysis of samples
US5619371A (en) * 1995-03-02 1997-04-08 Southern Research Institute Confocal optical microscopy system for multi-layer data storage and retrieval
EP0902885A4 (de) * 1996-05-16 2006-09-27 Affymetrix Inc System und verfahren zur erkennung markierter materialien
US5885840A (en) * 1997-02-10 1999-03-23 Compucyte Corp. Multiple assays of cell specimens
JP3180072B2 (ja) * 1997-09-11 2001-06-25 日立ソフトウエアエンジニアリング株式会社 発光パターン読み取り装置
GB9810350D0 (en) * 1998-05-14 1998-07-15 Ciba Geigy Ag Organic compounds
CA2273616A1 (en) * 1998-06-08 1999-12-08 The Board Of Trustees Of The Leland Stanford Junior University Method for parallel screening of allelic variation
JP2002530786A (ja) * 1998-10-30 2002-09-17 バースタイン・ラボラトリーズ・インコーポレイテッド 同時読み取り可能な解析分析材料を備えたトラッキング可能な光ディスク
US6514768B1 (en) * 1999-01-29 2003-02-04 Surmodics, Inc. Replicable probe array
US6403317B1 (en) * 1999-03-26 2002-06-11 Affymetrix, Inc. Electronic detection of hybridization on nucleic acid arrays
AU762085B2 (en) * 1999-04-13 2003-06-19 Chromavision Medical Systems, Inc. Histological reconstruction and automated image analysis
US20010055764A1 (en) * 1999-05-07 2001-12-27 Empedocles Stephen A. Microarray methods utilizing semiconductor nanocrystals
JP3820806B2 (ja) * 1999-07-21 2006-09-13 三菱電機株式会社 レーザ検査装置
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WO2002014462A1 (en) * 2000-08-14 2002-02-21 The Regents Of The University Of California Biosensors and methods for their use
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Also Published As

Publication number Publication date
CN101031660B (zh) 2011-03-30
EP1797195B1 (de) 2010-12-22
WO2006038149A1 (en) 2006-04-13
US20070254376A1 (en) 2007-11-01
EP1797195A1 (de) 2007-06-20
DE602005025508D1 (de) 2011-02-03
CN101031660A (zh) 2007-09-05
JP2008514950A (ja) 2008-05-08

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