ATE382147T1 - Verfahren und einrichtung zur hochempfindlichen detektion der anwesenheit von dna und weitere sonden - Google Patents
Verfahren und einrichtung zur hochempfindlichen detektion der anwesenheit von dna und weitere sondenInfo
- Publication number
- ATE382147T1 ATE382147T1 AT03760533T AT03760533T ATE382147T1 AT E382147 T1 ATE382147 T1 AT E382147T1 AT 03760533 T AT03760533 T AT 03760533T AT 03760533 T AT03760533 T AT 03760533T AT E382147 T1 ATE382147 T1 AT E382147T1
- Authority
- AT
- Austria
- Prior art keywords
- target sample
- capacitive sensor
- binding site
- substrate
- conductive
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
- G01N27/221—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance by investigating the dielectric properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
- G01N27/226—Construction of measuring vessels; Electrodes therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/16—Phosphorus containing
- Y10T436/163333—Organic [e.g., chemical warfare agents, insecticides, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02447122A EP1376111A1 (de) | 2002-06-24 | 2002-06-24 | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE382147T1 true ATE382147T1 (de) | 2008-01-15 |
Family
ID=29717039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03760533T ATE382147T1 (de) | 2002-06-24 | 2003-06-24 | Verfahren und einrichtung zur hochempfindlichen detektion der anwesenheit von dna und weitere sonden |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7943394B2 (de) |
| EP (2) | EP1376111A1 (de) |
| AT (1) | ATE382147T1 (de) |
| AU (1) | AU2003243843A1 (de) |
| DE (1) | DE60318313T2 (de) |
| WO (1) | WO2004001403A1 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0114399D0 (en) * | 2001-06-13 | 2001-08-08 | Univ Liverpool | Substrates, biomaterials and methods |
| EP1376111A1 (de) | 2002-06-24 | 2004-01-02 | Universite Catholique De Louvain | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
| US7736890B2 (en) * | 2003-12-31 | 2010-06-15 | President And Fellows Of Harvard College | Assay device and method |
| US7326908B2 (en) | 2004-04-19 | 2008-02-05 | Edward Sargent | Optically-regulated optical emission using colloidal quantum dot nanocrystals |
| US7746681B2 (en) | 2005-01-07 | 2010-06-29 | Invisage Technologies, Inc. | Methods of making quantum dot films |
| US7773404B2 (en) | 2005-01-07 | 2010-08-10 | Invisage Technologies, Inc. | Quantum dot optical devices with enhanced gain and sensitivity and methods of making same |
| US7742322B2 (en) | 2005-01-07 | 2010-06-22 | Invisage Technologies, Inc. | Electronic and optoelectronic devices with quantum dot films |
| DE102004045210A1 (de) * | 2004-09-17 | 2006-04-06 | Infineon Technologies Ag | Sensor-Anordnung und Verfahren zum Ermitteln eines Sensorereignisses |
| KR100678291B1 (ko) * | 2004-11-11 | 2007-02-02 | 삼성전자주식회사 | 나노입자를 이용한 수광소자 |
| CA2519608A1 (en) | 2005-01-07 | 2006-07-07 | Edward Sargent | Quantum dot-polymer nanocomposite photodetectors and photovoltaics |
| DE102005027245A1 (de) * | 2005-06-13 | 2006-12-21 | Siemens Ag | Schaltkreisanordnung |
| EP1894009A2 (de) * | 2005-06-17 | 2008-03-05 | Koninklijke Philips Electronics N.V. | Genauer magnetischer biosensor |
| US20080206892A1 (en) * | 2005-06-17 | 2008-08-28 | Koninklijke Philips Electronics, N.V. | Rapid Magnetic Biosensor With Integrated Arrival Time Measuremnt |
| KR100714988B1 (ko) * | 2005-08-09 | 2007-05-09 | 삼성전자주식회사 | 산화막이 표면에 형성된 실리콘 구조물 표면을 이용한dna 정제 방법 및 정제장치 |
| ITPD20050365A1 (it) * | 2005-12-14 | 2007-06-15 | Univ Degli Studi Trieste | Metodo e sistema di riconoscimento di pattern genetici |
| KR20090033166A (ko) * | 2006-03-16 | 2009-04-01 | 알-아민 디라니 | 유전 감지 방법 및 시스템 |
| KR100777973B1 (ko) * | 2006-07-13 | 2007-11-29 | 한국표준과학연구원 | 다중선형전극 센서 유닛으로 이루어진 바이오센서 |
| EP1898211A1 (de) * | 2006-09-08 | 2008-03-12 | Université Catholique de Louvain | Isolierter Substratimpedanzwandler |
| EP2017609A1 (de) * | 2007-07-18 | 2009-01-21 | Université Catholique de Louvain | Verfahren und Vorrichtung zum hochempfindlichen quantitativen Nachweis von chemischen/biologischen Molekülen |
| US8159347B2 (en) * | 2008-09-25 | 2012-04-17 | General Electric Company | Sensors having gap based sensing devices and methods of making and using the same |
| EP2182359B1 (de) * | 2008-10-30 | 2015-03-04 | Sysmex Corporation | Verfahren zur analytdetektion |
| WO2010099618A1 (en) | 2009-03-04 | 2010-09-10 | Al-Amin Dhirani | Conductance detection system and method |
| US8744568B2 (en) * | 2009-12-22 | 2014-06-03 | Boston Scientific Scimed, Inc. | Medical device with electroactive polymer powered by photovoltaic cell |
| JP2011232328A (ja) * | 2010-04-09 | 2011-11-17 | Hitachi Ltd | 生体物質検出アレイ、計測装置および計測方法 |
| KR20110128754A (ko) * | 2010-05-24 | 2011-11-30 | 한국생명공학연구원 | 극미량 시료 검출용 전기 바이오센서 |
| CN102888454B (zh) * | 2011-09-13 | 2015-04-22 | 中国水产科学研究院黄海水产研究所 | 非接触式基因扩增电化学快速检测方法 |
| US8986523B2 (en) | 2012-01-19 | 2015-03-24 | International Business Machines Corporation | Biosensor capacitor |
| US9382579B2 (en) * | 2012-03-02 | 2016-07-05 | Nokomis, Inc. | DNA/nanoparticle complex enhanced radio frequency transponder: structure of mark for detecting hybridization state and authenticating and tracking articles, method of preparing the same, and method of authenticating the same |
| JP2017507341A (ja) | 2014-03-07 | 2017-03-16 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 分子分析のための3電極型機器および方法 |
| US10004433B2 (en) * | 2014-07-07 | 2018-06-26 | Verily Life Sciences Llc | Electrochemical sensor chip |
| KR102713216B1 (ko) | 2015-06-25 | 2024-10-02 | 로스웰 엠이 아이엔씨. | 바이오분자 센서들 및 방법들 |
| KR101754239B1 (ko) * | 2015-12-28 | 2017-07-06 | 한국과학기술연구원 | 수용체와 표적 생체물질의 반응을 이용한 교차 전극 바이오센서 |
| CN113985017A (zh) | 2016-01-14 | 2022-01-28 | 罗斯韦尔生物技术股份有限公司 | 分子传感器及相关方法 |
| CN109071212A (zh) | 2016-01-28 | 2018-12-21 | 罗斯韦尔生物技术股份有限公司 | 使用大规模分子电子传感器阵列测量分析物的方法和装置 |
| KR102763291B1 (ko) | 2016-01-28 | 2025-02-04 | 로스웰 엠이 아이엔씨. | 대량 병렬 dna 시퀀싱 장치 |
| CA3053103A1 (en) | 2016-02-09 | 2017-08-17 | Roswell Biotechnologies, Inc. | Electronic label-free dna and genome sequencing |
| US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
| US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
| US10585094B2 (en) * | 2016-09-01 | 2020-03-10 | The Governors Of The University Of Alberta | Devices and methods for nanoparticle enhanced impedance-based molecular sensing |
| EP3339833B1 (de) | 2016-12-22 | 2021-11-10 | Heraeus Nexensos GmbH | Sensor, insbesondere russsensor, verfahren zur herstellung eines sensors, insbesondere eines russsensors, und verwendung |
| CN110431148A (zh) | 2017-01-10 | 2019-11-08 | 罗斯威尔生命技术公司 | 用于dna数据存储的方法和系统 |
| CA3052140A1 (en) | 2017-01-19 | 2018-07-26 | Roswell Biotechnologies, Inc. | Solid state sequencing devices comprising two dimensional layer materials |
| US10508296B2 (en) | 2017-04-25 | 2019-12-17 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
| EP3615685B1 (de) | 2017-04-25 | 2025-02-19 | Roswell Biotechnologies, Inc | Enzymatische schaltungen für molekulare sensoren |
| EP3622086A4 (de) | 2017-05-09 | 2021-04-21 | Roswell Biotechnologies, Inc | Bindungssondenschaltungen für molekulare sensoren |
| CN111373049A (zh) | 2017-08-30 | 2020-07-03 | 罗斯威尔生命技术公司 | 用于dna数据存储的进行性酶分子电子传感器 |
| EP3694990A4 (de) | 2017-10-10 | 2022-06-15 | Roswell Biotechnologies, Inc. | Verfahren, vorrichtung und systeme zur amplikationsfreien dna-datenspeicherung |
| CN109142462B (zh) * | 2018-06-22 | 2021-05-04 | 思贝科斯(北京)科技有限公司 | 电导探针及其制造方法 |
| US11471789B2 (en) | 2018-07-12 | 2022-10-18 | Abb Schweiz Ag | Material phase with electrical lead |
| US11247165B2 (en) * | 2018-07-12 | 2022-02-15 | Abb Schweiz Ag | Material phase between conductive layers |
| EP3953491B8 (de) | 2019-04-12 | 2025-09-10 | Roswell Biotechnologies Inc. | Polycyclische aromatische brücken für molekulare elektronische sensoren |
| US12146852B2 (en) | 2019-09-06 | 2024-11-19 | Roswell Biotechnologies, Inc. | Methods of fabricating nanoscale structures usable in molecular sensors and other devices |
| KR102286263B1 (ko) * | 2019-10-23 | 2021-08-04 | 가천대학교 산학협력단 | 나노소재를 이용한 정전용량형 화학센서 및 그의 제조방법 |
| GB202003649D0 (en) * | 2020-03-13 | 2020-04-29 | Imperial College Innovations Ltd | Cleanroom-free integrated trimdol silicon transducer for genetic detection of pathogens |
| US20240006756A1 (en) * | 2020-11-27 | 2024-01-04 | Nokia Shanghai Bell Co., Ltd. | Decoupling apparatus, a radiation unit and antenna |
| CN120188034A (zh) * | 2022-11-07 | 2025-06-20 | 日本精工株式会社 | 测定方法、测定系统以及程序 |
| EP4474808A1 (de) * | 2023-06-07 | 2024-12-11 | ETH Zurich | Kapazitive mikroelektrodenvorrichtung zur erfassung einer biologischen aktivität in einer probe und verfahren zur verwendung solch einer mikroelektrodenvorrichtung |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS621967A (ja) | 1985-06-25 | 1987-01-07 | 松下電工株式会社 | 屋根の軒先瓦とけらば瓦との交差部の構造 |
| JPS6219767A (ja) * | 1985-07-19 | 1987-01-28 | Hitachi Ltd | パタ−ン検出型dna分離検出装置 |
| WO1990005300A1 (en) | 1988-11-10 | 1990-05-17 | Midwest Research Technologies, Inc. | Method for electrical detection of a binding reaction |
| US5156810A (en) | 1989-06-15 | 1992-10-20 | Biocircuits Corporation | Biosensors employing electrical, optical and mechanical signals |
| US5965452A (en) * | 1996-07-09 | 1999-10-12 | Nanogen, Inc. | Multiplexed active biologic array |
| CA2238003C (en) * | 1995-12-01 | 2005-02-22 | Innogenetics N.V. | Impedimetric detection system and method of production thereof |
| US5917264A (en) * | 1996-09-05 | 1999-06-29 | Nagano Keiki Co Ltd | Electrostatic capacitance type transducer and method for producing the same |
| US5922537A (en) * | 1996-11-08 | 1999-07-13 | N.o slashed.AB Immunoassay, Inc. | Nanoparticles biosensor |
| NZ504675A (en) * | 1997-08-08 | 2003-12-19 | Cyrano Sciences Inc | Techniques and systems for analyte detection |
| US6495892B2 (en) | 1997-08-08 | 2002-12-17 | California Institute Of Technology | Techniques and systems for analyte detection |
| AU8903998A (en) * | 1997-08-12 | 1999-03-01 | Fraunhofer Institut Siliziumtechnologie | Electrochemical reporter system for detecting analytical immunoassay and mol ecular biology procedures |
| US20020166764A1 (en) | 1997-08-12 | 2002-11-14 | University Of Southern California | Electrochemical sensor devices and methods for fast, reliable, and sensitive detection and quantitation of analytes |
| BE1011776A3 (nl) * | 1998-03-06 | 2000-01-11 | Vito | Sensor voor toepassing in metaalsmelten. |
| EP1070244A4 (de) | 1998-04-09 | 2002-04-17 | California Inst Of Techn | Elektronische techniken zum nachweis von analyten |
| US6236096B1 (en) * | 1998-10-06 | 2001-05-22 | National Science Council Of Republic Of China | Structure of a three-electrode capacitive pressure sensor |
| ATE225940T1 (de) * | 1999-05-19 | 2002-10-15 | Advanced Array Technologies S | Verfahren zur identifizierung und/oder quantifizierung einer zielverbindung |
| US20030096321A1 (en) | 1999-05-19 | 2003-05-22 | Jose Remacle | Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips |
| US20010053522A1 (en) * | 2000-04-28 | 2001-12-20 | Fuji Photo Film Co., Ltd. | DNA chip and reactive electrode |
| JP2002131155A (ja) * | 2000-10-30 | 2002-05-09 | Denso Corp | 感圧抵抗センサ |
| JP2002174611A (ja) * | 2000-12-08 | 2002-06-21 | Matsushita Electric Ind Co Ltd | 免疫電極センサー |
| US20020096119A1 (en) * | 2001-01-23 | 2002-07-25 | Kolozsvari Kevin L. | Pet Chair |
| US7531136B2 (en) * | 2001-11-26 | 2009-05-12 | Sony Deutschland Gmbh | Chemical sensor |
| EP1376111A1 (de) | 2002-06-24 | 2004-01-02 | Universite Catholique De Louvain | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
| KR20090033166A (ko) * | 2006-03-16 | 2009-04-01 | 알-아민 디라니 | 유전 감지 방법 및 시스템 |
| EP1898211A1 (de) * | 2006-09-08 | 2008-03-12 | Université Catholique de Louvain | Isolierter Substratimpedanzwandler |
-
2002
- 2002-06-24 EP EP02447122A patent/EP1376111A1/de not_active Withdrawn
-
2003
- 2003-06-24 WO PCT/BE2003/000109 patent/WO2004001403A1/en not_active Ceased
- 2003-06-24 AU AU2003243843A patent/AU2003243843A1/en not_active Abandoned
- 2003-06-24 DE DE60318313T patent/DE60318313T2/de not_active Expired - Lifetime
- 2003-06-24 AT AT03760533T patent/ATE382147T1/de not_active IP Right Cessation
- 2003-06-24 US US10/519,014 patent/US7943394B2/en not_active Expired - Fee Related
- 2003-06-24 EP EP03760533A patent/EP1516174B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004001403A1 (en) | 2003-12-31 |
| EP1376111A1 (de) | 2004-01-02 |
| US7943394B2 (en) | 2011-05-17 |
| US20050227373A1 (en) | 2005-10-13 |
| DE60318313T2 (de) | 2008-12-11 |
| EP1516174B1 (de) | 2007-12-26 |
| EP1516174A1 (de) | 2005-03-23 |
| AU2003243843A1 (en) | 2004-01-06 |
| DE60318313D1 (de) | 2008-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |