ATE478040T1 - Verfahren zur herstellung von kontrastmitteln - Google Patents

Verfahren zur herstellung von kontrastmitteln

Info

Publication number
ATE478040T1
ATE478040T1 AT06792978T AT06792978T ATE478040T1 AT E478040 T1 ATE478040 T1 AT E478040T1 AT 06792978 T AT06792978 T AT 06792978T AT 06792978 T AT06792978 T AT 06792978T AT E478040 T1 ATE478040 T1 AT E478040T1
Authority
AT
Austria
Prior art keywords
contrast agents
compound
formula
producing contrast
producing
Prior art date
Application number
AT06792978T
Other languages
English (en)
Inventor
Silvia Ceragioli
Giovanni Luca Ciarciello
Luciano Castiglia
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Application granted granted Critical
Publication of ATE478040T1 publication Critical patent/ATE478040T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AT06792978T 2005-09-13 2006-08-24 Verfahren zur herstellung von kontrastmitteln ATE478040T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05019852A EP1762563A1 (de) 2005-09-13 2005-09-13 Verfahren zur Herstellung von Kontrastmitteln
PCT/EP2006/065634 WO2007031390A1 (en) 2005-09-13 2006-08-24 Process for the preparation of contrast agents

Publications (1)

Publication Number Publication Date
ATE478040T1 true ATE478040T1 (de) 2010-09-15

Family

ID=35501122

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06792978T ATE478040T1 (de) 2005-09-13 2006-08-24 Verfahren zur herstellung von kontrastmitteln

Country Status (17)

Country Link
US (2) US7592482B2 (de)
EP (2) EP1762563A1 (de)
JP (1) JP5108769B2 (de)
KR (1) KR101358058B1 (de)
CN (1) CN101263108B (de)
AT (1) ATE478040T1 (de)
AU (1) AU2006290947B2 (de)
CA (1) CA2621339C (de)
DE (1) DE602006016320D1 (de)
DK (1) DK1948590T3 (de)
ES (1) ES2351166T3 (de)
HR (1) HRP20100565T1 (de)
IL (1) IL189643A (de)
NO (1) NO340308B1 (de)
PL (1) PL1948590T3 (de)
SI (1) SI1948590T1 (de)
WO (1) WO2007031390A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501988B2 (en) * 2008-04-17 2013-08-06 Ecolab Usa Inc. Synthesis and applications of amino carboxylates
EP2327395A1 (de) 2009-11-23 2011-06-01 Bracco Imaging S.p.A Verfahren zur Herstellung eines Gadobenatdimeglumin-Komplexes in einer festen Form
EP2338874A1 (de) 2009-12-16 2011-06-29 Bracco Imaging S.p.A Verfahren zur Herstellung von chelatierten Verbindungen
IT1403988B1 (it) * 2010-07-15 2013-11-08 Bracco Imaging Spa Processo per la preparazione di agenti di contrasto.
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
KR101832027B1 (ko) * 2011-11-25 2018-04-04 바이오포어 인디아 파머슈티컬스 피브이티. 엘티디. 폴리아미노카르복실레이트의 정제 공정
CN102603550B (zh) * 2012-02-16 2014-11-26 佛山普正医药科技有限公司 一种中间体bopta的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2033433T3 (es) * 1987-07-16 1993-03-16 Nycomed As Procedimiento para preparar acidos aminopolicarboxilicos y sus derivados.
EP0703790B1 (de) * 1993-06-02 2000-08-16 BRACCO S.p.A. Iodierte paramagnetische chelaten, und deren verwendung als kontrastmittel
IT1291624B1 (it) * 1997-04-18 1999-01-11 Bracco Spa Chelati complessi di metalli paramagnetici a bassa tossicita'
ITMI981583A1 (it) * 1998-07-10 2000-01-10 Bracco Spa Processo per la preparazione dell'acido 4 -carbossi-5,8,11-tris (carbossimetil)-1-fenil-2-oxa-5,8,11-triazatridecan-13-oico
JP5004438B2 (ja) * 2005-06-09 2012-08-22 行政院原子能委員会核能研究所 Ｄｔｐａ誘導体の製造方法

Also Published As

Publication number Publication date
AU2006290947A1 (en) 2007-03-22
CA2621339C (en) 2011-04-26
CN101263108A (zh) 2008-09-10
ES2351166T3 (es) 2011-02-01
EP1948590B1 (de) 2010-08-18
IL189643A (en) 2012-03-29
NO340308B1 (no) 2017-03-27
JP2009507882A (ja) 2009-02-26
WO2007031390A1 (en) 2007-03-22
SI1948590T1 (sl) 2010-12-31
KR20080045724A (ko) 2008-05-23
EP1948590A1 (de) 2008-07-30
US7592482B2 (en) 2009-09-22
JP5108769B2 (ja) 2012-12-26
AU2006290947B2 (en) 2012-01-19
CN101263108B (zh) 2011-12-21
HRP20100565T1 (hr) 2010-11-30
DK1948590T3 (da) 2010-11-29
CA2621339A1 (en) 2007-03-22
US20090306424A1 (en) 2009-12-10
DE602006016320D1 (de) 2010-09-30
US20090118537A1 (en) 2009-05-07
PL1948590T3 (pl) 2011-03-31
NO20081655L (no) 2008-04-09
EP1762563A1 (de) 2007-03-14
KR101358058B1 (ko) 2014-02-06

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