DE602006016320D1 - - Google Patents

Info

Publication number
DE602006016320D1
DE602006016320D1 DE602006016320T DE602006016320T DE602006016320D1 DE 602006016320 D1 DE602006016320 D1 DE 602006016320D1 DE 602006016320 T DE602006016320 T DE 602006016320T DE 602006016320 T DE602006016320 T DE 602006016320T DE 602006016320 D1 DE602006016320 D1 DE 602006016320D1
Authority
DE
Germany
Prior art keywords
compound
formula
preparing
monitoring
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006016320T
Other languages
English (en)
Inventor
Silvia Ceragioli
Giovanni Luca Ciarciello
Luciano Castiglia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Imaging SpA
Original Assignee
Bracco Imaging SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging SpA filed Critical Bracco Imaging SpA
Publication of DE602006016320D1 publication Critical patent/DE602006016320D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE602006016320T 2005-09-13 2006-08-24 Active DE602006016320D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05019852A EP1762563A1 (de) 2005-09-13 2005-09-13 Verfahren zur Herstellung von Kontrastmitteln
PCT/EP2006/065634 WO2007031390A1 (en) 2005-09-13 2006-08-24 Process for the preparation of contrast agents

Publications (1)

Publication Number Publication Date
DE602006016320D1 true DE602006016320D1 (de) 2010-09-30

Family

ID=35501122

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006016320T Active DE602006016320D1 (de) 2005-09-13 2006-08-24

Country Status (17)

Country Link
US (2) US7592482B2 (de)
EP (2) EP1762563A1 (de)
JP (1) JP5108769B2 (de)
KR (1) KR101358058B1 (de)
CN (1) CN101263108B (de)
AT (1) ATE478040T1 (de)
AU (1) AU2006290947B2 (de)
CA (1) CA2621339C (de)
DE (1) DE602006016320D1 (de)
DK (1) DK1948590T3 (de)
ES (1) ES2351166T3 (de)
HR (1) HRP20100565T1 (de)
IL (1) IL189643A (de)
NO (1) NO340308B1 (de)
PL (1) PL1948590T3 (de)
SI (1) SI1948590T1 (de)
WO (1) WO2007031390A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501988B2 (en) * 2008-04-17 2013-08-06 Ecolab Usa Inc. Synthesis and applications of amino carboxylates
EP2327395A1 (de) * 2009-11-23 2011-06-01 Bracco Imaging S.p.A Verfahren zur Herstellung eines Gadobenatdimeglumin-Komplexes in einer festen Form
EP2338874A1 (de) 2009-12-16 2011-06-29 Bracco Imaging S.p.A Verfahren zur Herstellung von chelatierten Verbindungen
IT1403988B1 (it) * 2010-07-15 2013-11-08 Bracco Imaging Spa Processo per la preparazione di agenti di contrasto.
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
BR112014012429A2 (pt) * 2011-11-25 2017-06-06 Biophore India Pharmaceuticals Pvt Ltd rocesso para a purificação de poliaminocarboxilatos como dota, dtpa, do3a-butrol, bopta; e poliaminopolicarboxilato substancialmente puro
CN102603550B (zh) * 2012-02-16 2014-11-26 佛山普正医药科技有限公司 一种中间体bopta的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE137228T1 (de) * 1987-07-16 1996-05-15 Nycomed Imaging As Aminocarbonsäure und derivate
ATE195432T1 (de) * 1993-06-02 2000-09-15 Bracco Spa Iodierte paramagnetische chelaten, und deren verwendung als kontrastmittel
IT1291624B1 (it) * 1997-04-18 1999-01-11 Bracco Spa Chelati complessi di metalli paramagnetici a bassa tossicita'
ITMI981583A1 (it) * 1998-07-10 2000-01-10 Bracco Spa Processo per la preparazione dell'acido 4 -carbossi-5,8,11-tris (carbossimetil)-1-fenil-2-oxa-5,8,11-triazatridecan-13-oico
JP5004438B2 (ja) * 2005-06-09 2012-08-22 行政院原子能委員会核能研究所 Ｄｔｐａ誘導体の製造方法

Also Published As

Publication number Publication date
AU2006290947B2 (en) 2012-01-19
HRP20100565T1 (hr) 2010-11-30
IL189643A (en) 2012-03-29
EP1762563A1 (de) 2007-03-14
CA2621339C (en) 2011-04-26
AU2006290947A1 (en) 2007-03-22
CN101263108B (zh) 2011-12-21
US7592482B2 (en) 2009-09-22
ATE478040T1 (de) 2010-09-15
US20090306424A1 (en) 2009-12-10
WO2007031390A1 (en) 2007-03-22
JP2009507882A (ja) 2009-02-26
SI1948590T1 (sl) 2010-12-31
KR101358058B1 (ko) 2014-02-06
CN101263108A (zh) 2008-09-10
EP1948590A1 (de) 2008-07-30
NO20081655L (no) 2008-04-09
US20090118537A1 (en) 2009-05-07
DK1948590T3 (da) 2010-11-29
NO340308B1 (no) 2017-03-27
EP1948590B1 (de) 2010-08-18
KR20080045724A (ko) 2008-05-23
ES2351166T3 (es) 2011-02-01
JP5108769B2 (ja) 2012-12-26
CA2621339A1 (en) 2007-03-22
PL1948590T3 (pl) 2011-03-31

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