ATE449861T1 - Verfahren zur fermentativen herstellung von heterologen genprodukten in milchsäurebakterien - Google Patents
Verfahren zur fermentativen herstellung von heterologen genprodukten in milchsäurebakterienInfo
- Publication number
- ATE449861T1 ATE449861T1 AT01978228T AT01978228T ATE449861T1 AT E449861 T1 ATE449861 T1 AT E449861T1 AT 01978228 T AT01978228 T AT 01978228T AT 01978228 T AT01978228 T AT 01978228T AT E449861 T1 ATE449861 T1 AT E449861T1
- Authority
- AT
- Austria
- Prior art keywords
- lactic acid
- acid bacteria
- heterologue
- gene products
- fermentative production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69220500A | 2000-10-20 | 2000-10-20 | |
| PCT/DK2001/000693 WO2002033109A2 (en) | 2000-10-20 | 2001-10-19 | Fermentation method for production of heterologous gene products in lactic acid bacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449861T1 true ATE449861T1 (de) | 2009-12-15 |
Family
ID=24779648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01978228T ATE449861T1 (de) | 2000-10-20 | 2001-10-19 | Verfahren zur fermentativen herstellung von heterologen genprodukten in milchsäurebakterien |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7358067B2 (de) |
| EP (1) | EP1356073B1 (de) |
| JP (1) | JP4399158B2 (de) |
| AT (1) | ATE449861T1 (de) |
| AU (2) | AU2002210401B2 (de) |
| CA (1) | CA2426084C (de) |
| DE (1) | DE60140626D1 (de) |
| DK (1) | DK1356073T3 (de) |
| ES (1) | ES2336647T3 (de) |
| NZ (1) | NZ525394A (de) |
| PT (1) | PT1356073E (de) |
| WO (1) | WO2002033109A2 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9521568D0 (en) * | 1995-10-20 | 1995-12-20 | Lynxvale Ltd | Delivery of biologically active polypeptides |
| EP1239032A1 (de) * | 2001-03-02 | 2002-09-11 | Société des Produits Nestlé S.A. | Milchsäurebakterien als Mitteln zur Behandlung und Vorbeugung von Allergie |
| US7780961B2 (en) * | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
| EP1560935A2 (de) * | 2002-11-15 | 2005-08-10 | VIB vzw | Selbst-enthaldender lactobacillus strain |
| EP1708741B1 (de) * | 2003-12-24 | 2016-03-30 | Aduro Biotech | Fusionsproteine kodierende rekombinante nucleinsäure-moleküle mit antigenen und bakteriellen sekretorischen signal-polypeptiden, expressionskassetten und bakterien und anwendungsverfahren dafür |
| US7842289B2 (en) | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| US20070048823A1 (en) * | 2005-08-26 | 2007-03-01 | Cerenis Therapeutics, S.A. | Compositions and Methods for Producing Apolipoprotein Gene Products in Lactic Acid Bacteria |
| GB0522303D0 (en) * | 2005-11-01 | 2005-12-07 | Chiron Srl | Culture method |
| DK2119450T3 (da) | 2005-11-29 | 2013-05-06 | Actogenix Nv | Induktion af mucosal tolerance over for pankreatisk ø-beta-celle-autoantigener |
| UA95795C2 (ru) * | 2006-01-27 | 2011-09-12 | Юниверсити Оф Массачусетс | Способ изготовления продукта из биомассы и установка по производству топлива из биомассы |
| US7935804B2 (en) | 2006-03-01 | 2011-05-03 | Aduro Biotech | Engineered Listeria and methods of use thereof |
| RU2495129C2 (ru) * | 2007-01-12 | 2013-10-10 | Актогеникс Н.В. | ПРОМОТОРЫ Lactococcus И ИХ ПРИМЕНЕНИЕ: |
| CA3037889C (en) | 2007-01-25 | 2022-09-13 | Intrexon Actobiotics Nv | Treatment of immune disease by mucosal delivery of antigens |
| JP5576115B2 (ja) * | 2007-04-26 | 2014-08-20 | 中外製薬株式会社 | 高濃度アミノ酸含有培地を用いた細胞の培養方法 |
| AU2009219150A1 (en) * | 2008-02-27 | 2009-09-03 | Qteros, Inc. | Methods for the conversion of plant materials into fuels and chemicals by sequential action of two microorganisms |
| US20090286294A1 (en) * | 2008-04-04 | 2009-11-19 | University Of Massachusetts | Methods and Compositions for Improving the Production of Fuels in Microorganisms |
| US20100105114A1 (en) * | 2008-06-11 | 2010-04-29 | University Of Massachusetts | Methods and Compositions for Regulating Sporulation |
| CA2735909C (en) * | 2008-09-08 | 2019-05-21 | Jurag Separation A/S | Process for controlling the ph and level of target ions of a liquid composition |
| US20100086981A1 (en) * | 2009-06-29 | 2010-04-08 | Qteros, Inc. | Compositions and methods for improved saccharification of biomass |
| BRPI1013829A2 (pt) * | 2009-04-20 | 2019-09-24 | Qteros Inc | composições e métodos para fermentação de biomassa |
| EP2275527A1 (de) | 2009-07-17 | 2011-01-19 | ActoGeniX NV | Kulturmedium zur Fermentation von Bakterien welches frei von tierischen Bestandteilen ist |
| PL3202785T3 (pl) | 2009-10-26 | 2024-08-12 | F. Hoffmann-La Roche Ag | Sposób wytwarzania glikozylowanej immunoglobuliny |
| WO2011081658A2 (en) * | 2009-12-15 | 2011-07-07 | Qteros, Inc. | Methods and compositions for producing chemical products from c. phytofermentants |
| GB2478791A (en) * | 2010-03-19 | 2011-09-21 | Qteros Inc | Ethanol production by genetically-modified bacteria |
| PL2625262T3 (pl) | 2010-10-05 | 2016-05-31 | Novo Nordisk Healthcare Ag | Sposób wytwarzania białka |
| JP5979684B2 (ja) * | 2011-12-15 | 2016-08-24 | セラム インスティチュート オブ インディア プライベイト リミテッド | 莢膜多糖の収量向上のための細菌培養方法 |
| NZ627372A (en) | 2012-01-12 | 2016-04-29 | Auxilium Int Holdings Inc | Clostridium histolyticum enzymes and methods for the use thereof |
| BR112015032960B1 (pt) | 2013-07-04 | 2021-01-05 | F. Hoffmann-La Roche Ag | imunoensaio suprimido por interferência para detectar anticorpos anti-fármaco em amostras de soro |
| CN104988107B (zh) * | 2015-05-19 | 2018-06-08 | 中国农业科学院兰州兽医研究所 | 一种高效表达口蹄疫病毒抗原基因的重组乳酸杆菌及其制备方法和应用 |
| KR101915950B1 (ko) * | 2018-01-09 | 2018-11-07 | 주식회사 쎌바이오텍 | 시스타틴을 발현 및 분비하는 위장관 질환 치료 약물 전달용 미생물 및 그를 포함하는 위장관 질환 예방 또는 치료용 약제학적 조성물 |
| KR101915951B1 (ko) * | 2018-01-09 | 2018-11-07 | 주식회사 쎌바이오텍 | P8 단백질을 발현 및 분비하는 위장관 질환 치료 약물 전달용 미생물 및 그를 포함하는 위장관 질환 예방 또는 치료용 약제학적 조성물 |
| KR102281858B1 (ko) * | 2019-09-11 | 2021-07-26 | 주식회사 쎌바이오텍 | 유산균 유래 p8 단백질의 발현 컨스트럭트를 포함하는 대장 질환의 치료 또는 예방용 조성물 |
| CN111254103B (zh) * | 2019-11-19 | 2023-06-02 | 河南省生物工程技术研究中心 | 一种非洲猪瘟基因工程疫苗高密度发酵补料培养基及发酵工艺 |
| CN112795527A (zh) * | 2021-03-05 | 2021-05-14 | 昆明理工大学 | 二氢蝶呤醛缩酶基因的用途 |
| CN112813085B (zh) * | 2021-03-05 | 2023-03-31 | 昆明理工大学 | 焦磷酸酶基因的用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ286635A (en) * | 1992-12-30 | 1997-06-24 | Chr Hansen As | Recombinant lactic acid bacterium, dna containing a lactic acid promoter |
| ATE226637T1 (de) * | 1996-09-06 | 2002-11-15 | Bioteknologisk Inst | Milchsäurebakterielles regulierbares expressionssystem |
| ES2276691T3 (es) | 1999-08-06 | 2007-07-01 | Bioneer A/S | Peptidos señales aislados de lactococcus lactis. |
-
2001
- 2001-10-19 PT PT01978228T patent/PT1356073E/pt unknown
- 2001-10-19 AT AT01978228T patent/ATE449861T1/de active
- 2001-10-19 NZ NZ525394A patent/NZ525394A/en not_active IP Right Cessation
- 2001-10-19 AU AU2002210401A patent/AU2002210401B2/en not_active Expired
- 2001-10-19 EP EP01978228A patent/EP1356073B1/de not_active Expired - Lifetime
- 2001-10-19 DK DK01978228.3T patent/DK1356073T3/da active
- 2001-10-19 JP JP2002536077A patent/JP4399158B2/ja not_active Expired - Lifetime
- 2001-10-19 ES ES01978228T patent/ES2336647T3/es not_active Expired - Lifetime
- 2001-10-19 CA CA2426084A patent/CA2426084C/en not_active Expired - Lifetime
- 2001-10-19 AU AU1040102A patent/AU1040102A/xx active Pending
- 2001-10-19 US US09/982,531 patent/US7358067B2/en not_active Expired - Lifetime
- 2001-10-19 DE DE60140626T patent/DE60140626D1/de not_active Expired - Lifetime
- 2001-10-19 WO PCT/DK2001/000693 patent/WO2002033109A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002210401B2 (en) | 2006-07-20 |
| EP1356073A2 (de) | 2003-10-29 |
| PT1356073E (pt) | 2010-02-15 |
| DK1356073T3 (da) | 2010-04-06 |
| AU1040102A (en) | 2002-04-29 |
| DE60140626D1 (de) | 2010-01-07 |
| EP1356073B1 (de) | 2009-11-25 |
| WO2002033109A2 (en) | 2002-04-25 |
| CA2426084A1 (en) | 2002-04-25 |
| JP2004511248A (ja) | 2004-04-15 |
| CA2426084C (en) | 2013-12-10 |
| US7358067B2 (en) | 2008-04-15 |
| NZ525394A (en) | 2005-12-23 |
| US20020137140A1 (en) | 2002-09-26 |
| WO2002033109A3 (en) | 2003-09-04 |
| JP4399158B2 (ja) | 2010-01-13 |
| ES2336647T3 (es) | 2010-04-15 |
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| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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