ATE448244T1 - Proteinfragmente die polyepitope des nef proteins von hiv umfassen, deren herstellung und verwendungen insbesondere zur impfung - Google Patents
Proteinfragmente die polyepitope des nef proteins von hiv umfassen, deren herstellung und verwendungen insbesondere zur impfungInfo
- Publication number
- ATE448244T1 ATE448244T1 AT00936995T AT00936995T ATE448244T1 AT E448244 T1 ATE448244 T1 AT E448244T1 AT 00936995 T AT00936995 T AT 00936995T AT 00936995 T AT00936995 T AT 00936995T AT E448244 T1 ATE448244 T1 AT E448244T1
- Authority
- AT
- Austria
- Prior art keywords
- hiv
- derivatives
- nef
- induce
- protein
- Prior art date
Links
- 101710192141 Protein Nef Proteins 0.000 title abstract 3
- 239000012634 fragment Substances 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 3
- 241000700605 Viruses Species 0.000 abstract 2
- 230000007812 deficiency Effects 0.000 abstract 2
- 238000006467 substitution reaction Methods 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 206010057248 Cell death Diseases 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 102000008070 Interferon-gamma Human genes 0.000 abstract 1
- 108010074328 Interferon-gamma Proteins 0.000 abstract 1
- 102000015696 Interleukins Human genes 0.000 abstract 1
- 108010063738 Interleukins Proteins 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000009089 cytolysis Effects 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229940044627 gamma-interferon Drugs 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 229940047122 interleukins Drugs 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229930182852 proteinogenic amino acid Natural products 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9907012A FR2794370B1 (fr) | 1999-06-03 | 1999-06-03 | Fragments proteiques polyepitopiques, leur obtention et leurs utilisations notamment en vaccination |
| PCT/FR2000/001514 WO2000075181A1 (fr) | 1999-06-03 | 2000-05-31 | FRAGMENTS PROTEIQUES POLYEPITOPIQUES DE LA PROTEINE Nef DE HIV, LEUR OBTENTION ET LEURS UTILISATIONS NOTAMMENT EN VACCINATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE448244T1 true ATE448244T1 (de) | 2009-11-15 |
Family
ID=9546327
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00938875T ATE554172T1 (de) | 1999-06-03 | 2000-05-31 | Proteinfragmente die polyepitope der proteine e6 und e7 von hpv umfassen, deren herstellung und verwendung insbesondere zur impfung |
| AT00936995T ATE448244T1 (de) | 1999-06-03 | 2000-05-31 | Proteinfragmente die polyepitope des nef proteins von hiv umfassen, deren herstellung und verwendungen insbesondere zur impfung |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00938875T ATE554172T1 (de) | 1999-06-03 | 2000-05-31 | Proteinfragmente die polyepitope der proteine e6 und e7 von hpv umfassen, deren herstellung und verwendung insbesondere zur impfung |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6783763B1 (de) |
| EP (3) | EP1181314B8 (de) |
| AT (2) | ATE554172T1 (de) |
| AU (2) | AU5229400A (de) |
| CA (2) | CA2375602A1 (de) |
| DE (1) | DE60043299D1 (de) |
| ES (2) | ES2386803T3 (de) |
| FR (1) | FR2794370B1 (de) |
| WO (2) | WO2000075181A1 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL105554A (en) * | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
| CA2405363A1 (en) * | 2000-04-28 | 2001-11-08 | Ctl Immunotherapies Corp. | Epitope synchronization in antigen presenting cells |
| EP1355925A2 (de) * | 2000-12-08 | 2003-10-29 | Academisch Ziekenhuis Leiden | Lange peptide mit 22-45 aminosäureresten, die antigenspezifische immunreaktionen induzieren und/oder fördern |
| CA2431500C (en) | 2000-12-08 | 2016-06-07 | Sjoerd Hendrikus Van Der Burg | Long peptides of 22-45 amino acid residues that induce and/or enhance antigen specific immune responses |
| EP1213299A1 (de) * | 2000-12-08 | 2002-06-12 | Leids Universitair Medisch Centrum | Immunogene epitopen des menschlichen Papillom-Virus und deren Anwendung |
| FR2820425B1 (fr) * | 2001-02-08 | 2004-01-02 | Commissariat Energie Atomique | Melange de peptides issus d'une proteine nef et leurs applications |
| US6933123B2 (en) * | 2001-04-05 | 2005-08-23 | Yao Xiong Hu | Peptides from the E2, E6, and E7 proteins of human papilloma viruses 16 and 18 for detecting and/or diagnosing cervical and other human papillomavirus associated cancers |
| FR2824326B1 (fr) | 2001-05-04 | 2004-03-19 | Commissariat Energie Atomique | Melange de peptides issus des proteines e6 et/ou e7 de papillomavirus et leurs applications |
| CN100412087C (zh) | 2001-07-13 | 2008-08-20 | 泰哲医药研究(深圳)有限公司 | 序列号2的生物活性肽 |
| SG185137A1 (en) * | 2001-07-13 | 2012-11-29 | Cms Peptides Patent Holding Company Ltd | Biologically active peptides |
| SI1421200T1 (sl) * | 2001-08-23 | 2007-04-30 | Merck & Co Inc | Poskusi PCR fluorescentnih multipleks HPV-jev z uporabo vec fluoroforov |
| DE60238864D1 (de) | 2001-11-07 | 2011-02-17 | Mankind Corp | Für epitope von antigenen kodierende expressionsvektoren und verfahren zu deren konzeption |
| WO2004035795A1 (en) * | 2002-10-17 | 2004-04-29 | Bioleaders Corporation | Vector for anti-hpv vaccine and transformed microorganism by the vector |
| US20090028874A1 (en) * | 2003-12-24 | 2009-01-29 | Leiden University Medical Center | Synthetic Protein as Tumor-Specific Vaccine |
| AU2005222776A1 (en) * | 2003-12-31 | 2005-09-29 | Genimmune N.V. | Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions |
| EP1753845B1 (de) * | 2004-04-28 | 2018-01-03 | Headwaters Heavy Oil, LLC | Festbett-hydroprocessing-verfahren und -systeme und verfahren zur aufrüstung eines bestehenden festbettsystems |
| US10941353B2 (en) | 2004-04-28 | 2021-03-09 | Hydrocarbon Technology & Innovation, Llc | Methods and mixing systems for introducing catalyst precursor into heavy oil feedstock |
| MXPA06012528A (es) | 2004-04-28 | 2007-08-02 | Headwaters Heavy Oil Llc | Metodos y sistemas de hidroprocesamiento de lecho ebullente y metodos para mejorar un sistema de lecho ebullente existente. |
| WO2006063065A2 (en) | 2004-12-08 | 2006-06-15 | Gen-Probe Incorporated | Detection of nucleic acids from multiple types of human papillomaviruses |
| US20070037180A1 (en) * | 2005-02-10 | 2007-02-15 | Olle Nilsson | Site-specific immunization in order to establish antibodies with specificity for the E7 oncoprotein of high-risk HPV's |
| US7723472B2 (en) * | 2005-02-28 | 2010-05-25 | The Regents Of The University Of California | Extracellular matrix binding chimeric proteins and methods of use thereof |
| CN105063064B (zh) * | 2006-07-28 | 2024-09-24 | 宾夕法尼亚大学托管会 | 改进的疫苗及其使用方法 |
| US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
| EP2468763B1 (de) | 2007-05-31 | 2014-06-18 | Academisch Ziekenhuis Leiden h.o.d.n. LUMC | HPV-Epitope als Ziel für zervikale Tumoren infiltrierende T-Zellen zur Verwendung bei Impfstoffen |
| US8652482B2 (en) * | 2007-10-03 | 2014-02-18 | The Board Of Trustees Of The University Of Arkansas | HPV E6 protein T cell epitopes and uses thereof |
| EP2222336A2 (de) * | 2007-10-29 | 2010-09-01 | GENimmune N.V. | Verfahren und kits zur auslösung einer ctl-reaktion mit einem haupt-boost-schema |
| JP5267969B2 (ja) * | 2007-12-04 | 2013-08-21 | 学校法人慶應義塾 | 癌ワクチン |
| AU2009236306B2 (en) | 2008-04-17 | 2015-04-02 | Pds Biotechnology Corporation | Stimulation of an immune response by enantiomers of cationic lipids |
| EP2334317B1 (de) * | 2008-09-16 | 2017-06-14 | The Research Foundation Of State University Of New York | Geklammerte peptide und verfahren zu ihrer zusammensetzung |
| KR101471043B1 (ko) | 2009-01-08 | 2014-12-09 | 주식회사 바이오리더스 | 안정적인 항시적 고발현 자궁경부암 치료백신용 벡터 및 그에 의해 형질전환된 재조합 유산균 |
| CN102482327B (zh) * | 2009-06-22 | 2014-10-29 | 财团法人卫生研究院 | 脂质化肿瘤相关抗原及其免疫治疗的组成物及方法 |
| US20120225090A1 (en) * | 2009-08-03 | 2012-09-06 | The Johns Hopkins University | Methods for enhancing antigen-specific immune responses |
| WO2012116220A2 (en) | 2011-02-24 | 2012-08-30 | Qiagen Gaithersburg, Inc. | Materials and methods for detection of hpv nucleic acid |
| ES2689799T3 (es) * | 2011-09-12 | 2018-11-15 | Pds Biotechnology Corporation | Formulaciones de vacunas particuladas |
| US9790440B2 (en) | 2011-09-23 | 2017-10-17 | Headwaters Technology Innovation Group, Inc. | Methods for increasing catalyst concentration in heavy oil and/or coal resid hydrocracker |
| AU2013274235B2 (en) | 2012-06-15 | 2018-01-18 | Samir N. Khleif | Cationic lipid vaccine compositions and methods of use |
| US9644157B2 (en) | 2012-07-30 | 2017-05-09 | Headwaters Heavy Oil, Llc | Methods and systems for upgrading heavy oil using catalytic hydrocracking and thermal coking |
| AU2013317805B2 (en) | 2012-09-21 | 2018-07-26 | Pds Biotechnology Corporation | Improved vaccine compositions and methods of use |
| CN103342738B (zh) * | 2013-07-24 | 2015-02-18 | 广州恒上医药技术有限公司 | 人乳头瘤病毒e6蛋白可诱发同源蛋白间交叉反应性抗体的精细表位肽 |
| WO2016005789A1 (en) * | 2014-07-07 | 2016-01-14 | Institut Pasteur | Broad range gene and genotype papillomavirus transcriptome as a biomarker of papillomavirus- associated cancer stages |
| JP6325751B2 (ja) | 2014-11-04 | 2018-05-16 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | 治療用hpv16ワクチン |
| AU2016309743B2 (en) | 2015-08-20 | 2019-02-07 | Janssen Vaccines & Prevention B.V. | Therapeutic HPV18 vaccines |
| US11414608B2 (en) | 2015-09-22 | 2022-08-16 | Hydrocarbon Technology & Innovation, Llc | Upgraded ebullated bed reactor used with opportunity feedstocks |
| US11414607B2 (en) | 2015-09-22 | 2022-08-16 | Hydrocarbon Technology & Innovation, Llc | Upgraded ebullated bed reactor with increased production rate of converted products |
| US11612652B2 (en) | 2015-11-13 | 2023-03-28 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
| US10517944B2 (en) | 2016-05-02 | 2019-12-31 | Janssen Vaccines & Prevention B.V. | Therapeutic HPV vaccine combinations |
| WO2017210649A1 (en) * | 2016-06-03 | 2017-12-07 | Etubics Corporation | Compositions and methods for the treatment of human papillomavirus (hpv)-associated diseases |
| US11421164B2 (en) | 2016-06-08 | 2022-08-23 | Hydrocarbon Technology & Innovation, Llc | Dual catalyst system for ebullated bed upgrading to produce improved quality vacuum residue product |
| AU2017281389B2 (en) | 2016-06-20 | 2024-02-22 | Isa Pharmaceuticals B.V. | Formulation of a peptide vaccine |
| CN108164587A (zh) * | 2016-12-07 | 2018-06-15 | 中国医学科学院肿瘤医院 | 新的hpv抗原表位 |
| KR102505534B1 (ko) | 2017-03-02 | 2023-03-02 | 하이드로카본 테크놀로지 앤 이노베이션, 엘엘씨 | 오염 침전물이 적은 업그레이드된 에뷸레이티드 베드 반응기 |
| US11732203B2 (en) | 2017-03-02 | 2023-08-22 | Hydrocarbon Technology & Innovation, Llc | Ebullated bed reactor upgraded to produce sediment that causes less equipment fouling |
| CN111655238A (zh) | 2017-12-05 | 2020-09-11 | Pds生物科技公司 | 用于刺激i型干扰素基因的包括阳离子脂质的方法和组合物 |
| CA3088837A1 (en) * | 2018-01-24 | 2019-08-01 | The Council Of The Queensland Institute Of Medical Research | Hpv immunotherapy |
| CA3057131C (en) | 2018-10-17 | 2024-04-23 | Hydrocarbon Technology And Innovation, Llc | Upgraded ebullated bed reactor with no recycle buildup of asphaltenes in vacuum bottoms |
| US12497569B2 (en) | 2022-05-26 | 2025-12-16 | Hydrocarbon Technology & Innovation, Llc | Method and system for mixing catalyst precursor into heavy oil using a high boiling hydrocarbon diluent |
| WO2024223299A2 (en) | 2023-04-26 | 2024-10-31 | Isa Pharmaceuticals B.V. | Methods of treating cancer by administering immunogenic compositions and a pd-1 inhibitor |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4777239A (en) * | 1986-07-10 | 1988-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic peptides of human papilloma virus |
| FR2641081A1 (de) * | 1988-12-23 | 1990-06-29 | Medgenix Group | |
| AU650868B2 (en) * | 1990-03-20 | 1994-07-07 | Behringwerke Aktiengesellschaft | Seroreactive epitopes of human papillomavirus (HPV) 16 proteins |
| US5932412A (en) * | 1990-05-11 | 1999-08-03 | Euro-Diagnostica Ab | Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes |
| PT523391E (pt) | 1991-07-13 | 2003-08-29 | Dade Behring Marburg Gmbh | Utilizacao dos peptidos derivados dos genes hpv-16 e6 e e7 para fins de diagnostico |
| US6419931B1 (en) * | 1991-08-26 | 2002-07-16 | Epimmune Inc. | Compositions and methods for eliciting CTL immunity |
| IL105554A (en) * | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
| WO1995011255A1 (en) * | 1993-10-19 | 1995-04-27 | Ajinomoto Co., Inc. | Peptide capable of inducing immune response against hiv and aids preventive or remedy containing the peptide |
| AUPN015794A0 (en) * | 1994-12-20 | 1995-01-19 | Csl Limited | Variants of human papilloma virus antigens |
| DE69723434T2 (de) * | 1996-04-26 | 2004-05-19 | Rijksuniversiteit Te Leiden | Verfahren zur selektion und produktion von t-zell-peptide epitope und vakzine mit diese epitope |
| AUPO390396A0 (en) * | 1996-11-29 | 1996-12-19 | Csl Limited | Novel promiscuous T helper cell epitopes |
| FR2771640B1 (fr) * | 1997-12-03 | 2000-02-11 | Inst Nat Sante Rech Med | Micelles mixtes de lipopeptides pour l'induction d'une reponse immunitaire et leurs utilisations a des fins therapeutiques |
-
1999
- 1999-06-03 FR FR9907012A patent/FR2794370B1/fr not_active Expired - Lifetime
-
2000
- 2000-05-31 AU AU52294/00A patent/AU5229400A/en not_active Abandoned
- 2000-05-31 DE DE60043299T patent/DE60043299D1/de not_active Expired - Lifetime
- 2000-05-31 AU AU54110/00A patent/AU5411000A/en not_active Abandoned
- 2000-05-31 CA CA002375602A patent/CA2375602A1/fr not_active Abandoned
- 2000-05-31 AT AT00938875T patent/ATE554172T1/de active
- 2000-05-31 WO PCT/FR2000/001514 patent/WO2000075181A1/fr not_active Ceased
- 2000-05-31 EP EP00936995A patent/EP1181314B8/de not_active Expired - Lifetime
- 2000-05-31 EP EP00938875A patent/EP1183368B1/de not_active Expired - Lifetime
- 2000-05-31 CA CA002375627A patent/CA2375627A1/en not_active Abandoned
- 2000-05-31 ES ES00938875T patent/ES2386803T3/es not_active Expired - Lifetime
- 2000-05-31 EP EP10177363.8A patent/EP2267132B1/de not_active Expired - Lifetime
- 2000-05-31 WO PCT/FR2000/001513 patent/WO2000075336A2/fr not_active Ceased
- 2000-05-31 AT AT00936995T patent/ATE448244T1/de not_active IP Right Cessation
- 2000-05-31 US US09/980,523 patent/US6783763B1/en not_active Expired - Lifetime
- 2000-05-31 ES ES10177363.8T patent/ES2509901T3/es not_active Expired - Lifetime
-
2004
- 2004-06-02 US US10/858,384 patent/US7288258B2/en not_active Expired - Fee Related
-
2007
- 2007-09-21 US US11/859,320 patent/US20080248044A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1181314A1 (de) | 2002-02-27 |
| FR2794370B1 (fr) | 2003-10-17 |
| US20080248044A1 (en) | 2008-10-09 |
| EP1183368B1 (de) | 2012-04-18 |
| FR2794370A1 (fr) | 2000-12-08 |
| EP1183368A2 (de) | 2002-03-06 |
| WO2000075336A3 (fr) | 2001-07-26 |
| AU5229400A (en) | 2000-12-28 |
| EP1181314B8 (de) | 2010-02-17 |
| US20050033025A1 (en) | 2005-02-10 |
| US7288258B2 (en) | 2007-10-30 |
| EP2267132A2 (de) | 2010-12-29 |
| CA2375627A1 (en) | 2000-12-14 |
| CA2375602A1 (fr) | 2000-12-14 |
| ES2509901T3 (es) | 2014-10-20 |
| WO2000075181A1 (fr) | 2000-12-14 |
| EP1181314B1 (de) | 2009-11-11 |
| DE60043299D1 (de) | 2009-12-24 |
| ATE554172T1 (de) | 2012-05-15 |
| US6783763B1 (en) | 2004-08-31 |
| EP2267132B1 (de) | 2014-07-16 |
| EP2267132A3 (de) | 2011-04-20 |
| AU5411000A (en) | 2000-12-28 |
| ES2386803T3 (es) | 2012-08-31 |
| WO2000075336A2 (fr) | 2000-12-14 |
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