ATE430797T1 - Vorrichtung und verfahren zur fermentativen herstellung biologisch wirksamer verbindungen - Google Patents

Vorrichtung und verfahren zur fermentativen herstellung biologisch wirksamer verbindungen

Info

Publication number
ATE430797T1
ATE430797T1 AT06754069T AT06754069T ATE430797T1 AT E430797 T1 ATE430797 T1 AT E430797T1 AT 06754069 T AT06754069 T AT 06754069T AT 06754069 T AT06754069 T AT 06754069T AT E430797 T1 ATE430797 T1 AT E430797T1
Authority
AT
Austria
Prior art keywords
biologically effective
fermentative production
effective compounds
insulator
working chamber
Prior art date
Application number
AT06754069T
Other languages
English (en)
Inventor
Bernd Doelle
Michael Pfeil
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Application granted granted Critical
Publication of ATE430797T1 publication Critical patent/ATE430797T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/14—Incubators; Climatic chambers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/04—Apparatus for enzymology or microbiology with gas introduction means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02—Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/809—Incubators or racks or holders for culture plates or containers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Thermal Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT06754069T 2005-06-17 2006-06-02 Vorrichtung und verfahren zur fermentativen herstellung biologisch wirksamer verbindungen ATE430797T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005028171 2005-06-17
PCT/EP2006/005272 WO2006133818A1 (de) 2005-06-17 2006-06-02 Vorrichtung und verfahren zur fermentativen herstellung biologisch wirksamer verbindungen

Publications (1)

Publication Number Publication Date
ATE430797T1 true ATE430797T1 (de) 2009-05-15

Family

ID=36954307

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06754069T ATE430797T1 (de) 2005-06-17 2006-06-02 Vorrichtung und verfahren zur fermentativen herstellung biologisch wirksamer verbindungen

Country Status (20)

Country Link
US (1) US7927836B2 (de)
EP (1) EP1891200B1 (de)
JP (1) JP4879978B2 (de)
KR (1) KR101176248B1 (de)
CN (1) CN101194010B (de)
AT (1) ATE430797T1 (de)
AU (1) AU2006257411B2 (de)
BR (1) BRPI0611752B8 (de)
CA (1) CA2612205C (de)
DE (1) DE602006006671D1 (de)
DK (1) DK1891200T3 (de)
EA (1) EA012052B1 (de)
ES (1) ES2326916T3 (de)
HK (1) HK1118573A1 (de)
HR (1) HRP20090382T1 (de)
IL (1) IL188141A (de)
PL (1) PL1891200T3 (de)
SI (1) SI1891200T1 (de)
WO (1) WO2006133818A1 (de)
ZA (1) ZA200709195B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009012570A (es) 2007-06-01 2010-03-15 Merz Pharma Gmbh & Co Kgaa Proceso para proveer un relajante muscular estable a la temperatura a base del componente neurotoxico de la toxina botulinica en forma solida.
US8171177B2 (en) 2007-06-28 2012-05-01 Apple Inc. Enhancements to data-driven media management within an electronic device
US7861008B2 (en) * 2007-06-28 2010-12-28 Apple Inc. Media management and routing within an electronic device
US8111837B2 (en) * 2007-06-28 2012-02-07 Apple Inc. Data-driven media management within an electronic device
US8041438B2 (en) * 2007-06-28 2011-10-18 Apple Inc. Data-driven media management within an electronic device
US8748151B2 (en) 2008-08-29 2014-06-10 Merz Pharma Gmbh & Co. Kgaa Clostridial neurotoxins with altered persistency
ES2426667T3 (es) 2008-09-09 2013-10-24 Susanne Grafe Toxina botulínica para introducir infertilidad temporal en un vertebrado (por ejemplo, un ser humano)
MX365496B (es) * 2009-10-21 2019-06-05 Revance Therapeutics Inc Metodos y sistemas para purificar la neurotoxina botulinica no acomplejada.
US9937245B2 (en) * 2013-07-30 2018-04-10 Merz Pharma Gmbh & Co. Kgaa Highly pure neurotoxic component of a botulinum toxin, process for preparing same, and uses thereof
EP3274044B1 (de) 2015-03-26 2023-03-01 Vensica Medical Ltd. Ultraschallarzneimittelabgabe in die harnblase
KR101884623B1 (ko) 2016-03-15 2018-09-07 주식회사 빅바이오젠 일체형 저온제습건조 고체발효기 및 이를 이용한 고체발효물의 미생물 생균 수와 생리영양활성 성분량 및 활성의 감소 최소화를 위한 고체발효 저온제습건조 방법
WO2019193591A1 (en) 2018-04-01 2019-10-10 Vensica Medical Ltd. System and method for ultrasonic bladder therapeutic agent delivery
KR102606876B1 (ko) 2023-06-29 2023-11-29 주식회사 빅바이오젠 고체발효 장치 및 방법

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3775256A (en) * 1971-10-14 1973-11-27 M Risinger Anaerobic bacteria laboratory
US4262091A (en) * 1979-04-27 1981-04-14 Anaerobe Systems Preparation of contaminant free containers of culture medium
JPS5779878A (en) * 1980-10-31 1982-05-19 Hitachi Ltd Safety cabinet
JPS6028276B2 (ja) * 1981-11-06 1985-07-03 日本電池株式会社 嫌気性グロ−ブボツクスの作動方法
DE4026061C1 (de) 1990-08-17 1992-02-13 Heraeus Sensor Gmbh, 6450 Hanau, De
US5424209A (en) * 1993-03-19 1995-06-13 Kearney; George P. Automated cell culture and testing system
US5882918A (en) * 1995-08-08 1999-03-16 Genespan Corporation Cell culture incubator
DE19925739A1 (de) * 1999-06-07 2000-12-21 Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh Therapeutikum mit einem Botulinum-Neurotoxin
JP3865354B2 (ja) * 2000-03-02 2007-01-10 高木産業株式会社 細胞又は組織の培養方法
WO2002005332A2 (en) * 2000-07-07 2002-01-17 Applied Materials, Inc. Loadlock chamber
JPWO2004011593A1 (ja) * 2002-07-31 2005-11-24 独立行政法人科学技術振興機構 生体由来の細胞または組織の自動培養装置
JP4300863B2 (ja) * 2003-04-25 2009-07-22 澁谷工業株式会社 無菌システムとその使用方法
JP4169668B2 (ja) * 2003-09-04 2008-10-22 株式会社美和製作所 バキュームグローブボックス
GB2407048B (en) * 2003-10-15 2007-07-11 Biotrace Internat Plc Laboratory apparatus
CN2693437Y (zh) * 2004-03-10 2005-04-20 赵明华 真空手套实验箱
DE102004043009A1 (de) * 2004-09-06 2006-03-23 Toxogen Gmbh Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen

Also Published As

Publication number Publication date
PL1891200T3 (pl) 2009-10-30
CN101194010B (zh) 2013-04-03
HRP20090382T1 (en) 2009-09-30
IL188141A0 (en) 2008-03-20
DK1891200T3 (da) 2009-07-27
EP1891200B1 (de) 2009-05-06
CA2612205C (en) 2012-07-10
US7927836B2 (en) 2011-04-19
AU2006257411A1 (en) 2006-12-21
KR101176248B1 (ko) 2012-08-22
IL188141A (en) 2011-02-28
KR20080018177A (ko) 2008-02-27
BRPI0611752B1 (pt) 2018-04-24
WO2006133818A1 (de) 2006-12-21
CN101194010A (zh) 2008-06-04
ES2326916T3 (es) 2009-10-21
EP1891200A1 (de) 2008-02-27
DE602006006671D1 (de) 2009-06-18
CA2612205A1 (en) 2006-12-21
ZA200709195B (en) 2008-10-29
HK1118573A1 (en) 2009-02-13
EA012052B1 (ru) 2009-08-28
BRPI0611752B8 (pt) 2021-05-25
BRPI0611752A2 (pt) 2010-09-28
US20080187967A1 (en) 2008-08-07
JP4879978B2 (ja) 2012-02-22
AU2006257411B2 (en) 2010-07-22
JP2009538596A (ja) 2009-11-12
EA200800076A1 (ru) 2008-04-28
SI1891200T1 (sl) 2009-10-31

Similar Documents

Publication Publication Date Title
ATE430797T1 (de) Vorrichtung und verfahren zur fermentativen herstellung biologisch wirksamer verbindungen
DE602006012274D1 (de) Verfahren und Vorrichtung zur Herstellung von Gruppe III Nitridkristall.
ATE447549T1 (de) Verfahren zur kontinuierlichen herstellung von isocyanaten
DE602006009833D1 (de) Verfahren und vorrichtung zur herstellung von synergistischem biozid
DE602007003225D1 (de) Verfahren zur herstellung eines stärkehydrolysats
FI20115723L (fi) Menetelmä ja laitteisto biologista alkuperää olevan materiaalin puhdistamiseksi
ATE486857T1 (de) Verfahren zur herstellung von telmisartan
ATE513872T1 (de) Verfahren zur herstellung von kautschukmischungen
TW200724674A (en) Hydrogen fermentation apparatus and production method of hydrogen
WO2009117453A3 (en) Organic waste decomposition system and method
ATE550944T1 (de) Pilzstämme und ein verfahren zur herstellung eines insektizids von diesen stämmen
DE602004029691D1 (de) Verfahren zur einführung eines gens in pflanzenmaterial
DE502007002401D1 (de) Vorrichtung zur nachbehandlung von reifen
ATE525364T1 (de) Verfahren zur herstellung von 3,6-dihydro-1,3,5- triazin-derivaten
ATE479488T1 (de) Verfahren und vorrichtung zur behandlung eines gasstroms
ATE466010T1 (de) Verfahren zur herstellung von candesartan
ATE426466T1 (de) Verfahren zur herstellung eines biostabilisierten waldsubstrats aus dem integralen zyklus stadtischer feststoffabfallverwertung
DE60307403D1 (de) Bakterien und Verfahren zur Herstellung von Riboflavin durch Fermentation
ATE516866T1 (de) Verfahren zur intensiven extraktion von zellulären verbindungen aus mikroorganismen durch kontinuierliche kultur und extraktion, und entsprechende vorrichtung
ATE486999T1 (de) Vorrichtung und verfahren zur herstellung von cellulosebasierten produkten
DE502005008101D1 (de) Verfahren zur herstellung von carbodiimidgruppen aufweisenden substanzen
ATE405554T1 (de) Verfahren zur herstellung von pramipexole
DE602006010694D1 (de) Verfahren zur herstellung von synthetischen diamanten
ATE503001T1 (de) Verfahren zum züchten von bakterien der familie der streptococcaceae
DE502004011486D1 (de) Antioxidationsmittel für organisches material und verfahren zur behandlung desselben

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1891200

Country of ref document: EP