BRPI0611752B8 - dispositivo e processo para produção fermentativa de compostos biologicamente ativos - Google Patents

dispositivo e processo para produção fermentativa de compostos biologicamente ativos

Info

Publication number
BRPI0611752B8
BRPI0611752B8 BRPI0611752A BRPI0611752A BRPI0611752B8 BR PI0611752 B8 BRPI0611752 B8 BR PI0611752B8 BR PI0611752 A BRPI0611752 A BR PI0611752A BR PI0611752 A BRPI0611752 A BR PI0611752A BR PI0611752 B8 BRPI0611752 B8 BR PI0611752B8
Authority
BR
Brazil
Prior art keywords
biologically active
active compounds
fermentative production
insulator
working chamber
Prior art date
Application number
BRPI0611752A
Other languages
English (en)
Inventor
Dölle Bernd
Pfeil Michael
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of BRPI0611752A2 publication Critical patent/BRPI0611752A2/pt
Publication of BRPI0611752B1 publication Critical patent/BRPI0611752B1/pt
Publication of BRPI0611752B8 publication Critical patent/BRPI0611752B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/14—Incubators; Climatic chambers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/04—Apparatus for enzymology or microbiology with gas introduction means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02—Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/809—Incubators or racks or holders for culture plates or containers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Thermal Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

dispositivo e processo para produção fermentativa de compostos biologicamente eficazes. a presente invenção refere-se a um processo e um dispositivo para a produção fermentativa de materiais biologicamente eficazes, sendo que o fermentador se encontra em um isolador, que se encontra novamente em uma câmara de trabalho ou é adjacente a esta e sendo que tanto no isolador, quanto também na câmara de trabalho predomina uma diferença de pressão em relação à pressão ambiente.
BRPI0611752A 2005-06-17 2006-06-02 dispositivo e processo para produção fermentativa de compostos biologicamente ativos BRPI0611752B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005028171.0 2005-06-17
DE102005028171 2005-06-17
PCT/EP2006/005272 WO2006133818A1 (de) 2005-06-17 2006-06-02 Vorrichtung und verfahren zur fermentativen herstellung biologisch wirksamer verbindungen

Publications (3)

Publication Number Publication Date
BRPI0611752A2 BRPI0611752A2 (pt) 2010-09-28
BRPI0611752B1 BRPI0611752B1 (pt) 2018-04-24
BRPI0611752B8 true BRPI0611752B8 (pt) 2021-05-25

Family

ID=36954307

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0611752A BRPI0611752B8 (pt) 2005-06-17 2006-06-02 dispositivo e processo para produção fermentativa de compostos biologicamente ativos

Country Status (20)

Country Link
US (1) US7927836B2 (pt)
EP (1) EP1891200B1 (pt)
JP (1) JP4879978B2 (pt)
KR (1) KR101176248B1 (pt)
CN (1) CN101194010B (pt)
AT (1) ATE430797T1 (pt)
AU (1) AU2006257411B2 (pt)
BR (1) BRPI0611752B8 (pt)
CA (1) CA2612205C (pt)
DE (1) DE602006006671D1 (pt)
DK (1) DK1891200T3 (pt)
EA (1) EA012052B1 (pt)
ES (1) ES2326916T3 (pt)
HK (1) HK1118573A1 (pt)
HR (1) HRP20090382T1 (pt)
IL (1) IL188141A (pt)
PL (1) PL1891200T3 (pt)
SI (1) SI1891200T1 (pt)
WO (1) WO2006133818A1 (pt)
ZA (1) ZA200709195B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2686642A1 (en) 2007-06-01 2008-12-04 Merz Pharma Gmbh & Co. Kgaa Process for providing a temperature - stable muscle relaxant on the basis of the neurotoxic component of botulinum toxin
US7861008B2 (en) * 2007-06-28 2010-12-28 Apple Inc. Media management and routing within an electronic device
US8111837B2 (en) * 2007-06-28 2012-02-07 Apple Inc. Data-driven media management within an electronic device
US8041438B2 (en) * 2007-06-28 2011-10-18 Apple Inc. Data-driven media management within an electronic device
US8171177B2 (en) 2007-06-28 2012-05-01 Apple Inc. Enhancements to data-driven media management within an electronic device
US8748151B2 (en) 2008-08-29 2014-06-10 Merz Pharma Gmbh & Co. Kgaa Clostridial neurotoxins with altered persistency
ES2426667T3 (es) 2008-09-09 2013-10-24 Susanne Grafe Toxina botulínica para introducir infertilidad temporal en un vertebrado (por ejemplo, un ser humano)
US20120196349A1 (en) * 2009-10-21 2012-08-02 Revance Therapeutics, Inc. Methods and Systems for Purifying Non-Complexed Botulinum Neurotoxin
EP3027641A1 (en) * 2013-07-30 2016-06-08 Merz Pharma GmbH & Co. KGaA Process for preparing a highly pure neurotoxic component of a botulinum toxin and uses thereof
EP3274044B1 (en) 2015-03-26 2023-03-01 Vensica Medical Ltd. Ultrasonic urinary bladder drug delivery
KR101884623B1 (ko) 2016-03-15 2018-09-07 주식회사 빅바이오젠 일체형 저온제습건조 고체발효기 및 이를 이용한 고체발효물의 미생물 생균 수와 생리영양활성 성분량 및 활성의 감소 최소화를 위한 고체발효 저온제습건조 방법
US11529506B2 (en) 2018-04-01 2022-12-20 Vensica Medical Ltd. System and method for ultrasonic bladder therapeutic agent delivery
KR102606876B1 (ko) 2023-06-29 2023-11-29 주식회사 빅바이오젠 고체발효 장치 및 방법

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US3775256A (en) * 1971-10-14 1973-11-27 M Risinger Anaerobic bacteria laboratory
US4262091A (en) * 1979-04-27 1981-04-14 Anaerobe Systems Preparation of contaminant free containers of culture medium
JPS5779878A (en) * 1980-10-31 1982-05-19 Hitachi Ltd Safety cabinet
JPS6028276B2 (ja) * 1981-11-06 1985-07-03 日本電池株式会社 嫌気性グロ−ブボツクスの作動方法
DE4026061C1 (pt) 1990-08-17 1992-02-13 Heraeus Sensor Gmbh, 6450 Hanau, De
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JP3865354B2 (ja) * 2000-03-02 2007-01-10 高木産業株式会社 細胞又は組織の培養方法
CN1440564A (zh) * 2000-07-07 2003-09-03 应用材料有限公司 锁料室
EP1548099A1 (en) * 2002-07-31 2005-06-29 Japan Science and Technology Agency Automatic culture apparatus for cell or tisse with biological origin
JP4300863B2 (ja) * 2003-04-25 2009-07-22 澁谷工業株式会社 無菌システムとその使用方法
JP4169668B2 (ja) * 2003-09-04 2008-10-22 株式会社美和製作所 バキュームグローブボックス
GB2407048B (en) * 2003-10-15 2007-07-11 Biotrace Internat Plc Laboratory apparatus
CN2693437Y (zh) * 2004-03-10 2005-04-20 赵明华 真空手套实验箱
DE102004043009A1 (de) * 2004-09-06 2006-03-23 Toxogen Gmbh Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen

Also Published As

Publication number Publication date
CN101194010B (zh) 2013-04-03
DE602006006671D1 (de) 2009-06-18
ES2326916T3 (es) 2009-10-21
DK1891200T3 (da) 2009-07-27
AU2006257411B2 (en) 2010-07-22
BRPI0611752B1 (pt) 2018-04-24
CA2612205A1 (en) 2006-12-21
CA2612205C (en) 2012-07-10
HK1118573A1 (en) 2009-02-13
WO2006133818A1 (de) 2006-12-21
EA012052B1 (ru) 2009-08-28
ZA200709195B (en) 2008-10-29
US20080187967A1 (en) 2008-08-07
ATE430797T1 (de) 2009-05-15
HRP20090382T1 (en) 2009-09-30
JP2009538596A (ja) 2009-11-12
PL1891200T3 (pl) 2009-10-30
AU2006257411A1 (en) 2006-12-21
KR101176248B1 (ko) 2012-08-22
EP1891200B1 (en) 2009-05-06
IL188141A (en) 2011-02-28
BRPI0611752A2 (pt) 2010-09-28
EA200800076A1 (ru) 2008-04-28
KR20080018177A (ko) 2008-02-27
IL188141A0 (en) 2008-03-20
CN101194010A (zh) 2008-06-04
US7927836B2 (en) 2011-04-19
SI1891200T1 (sl) 2009-10-31
JP4879978B2 (ja) 2012-02-22
EP1891200A1 (de) 2008-02-27

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/06/2006 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF