ATE428441T1 - Zusammensetzungen und verfahren zur modulation einer immunantwort auf ein antigen durch verabreichung von zytokine-beladenen zellen - Google Patents
Zusammensetzungen und verfahren zur modulation einer immunantwort auf ein antigen durch verabreichung von zytokine-beladenen zellenInfo
- Publication number
- ATE428441T1 ATE428441T1 AT99930120T AT99930120T ATE428441T1 AT E428441 T1 ATE428441 T1 AT E428441T1 AT 99930120 T AT99930120 T AT 99930120T AT 99930120 T AT99930120 T AT 99930120T AT E428441 T1 ATE428441 T1 AT E428441T1
- Authority
- AT
- Austria
- Prior art keywords
- antigen
- cytokine
- modulating
- administration
- compositions
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000028993 immune response Effects 0.000 title 1
- 108010029697 CD40 Ligand Proteins 0.000 abstract 2
- 102100032937 CD40 ligand Human genes 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 101150013553 CD40 gene Proteins 0.000 abstract 1
- 102100040245 Tumor necrosis factor receptor superfamily member 5 Human genes 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001129—Molecules with a "CD" designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8678098P | 1998-05-26 | 1998-05-26 | |
| US9152598P | 1998-07-02 | 1998-07-02 | |
| PCT/US1999/011609 WO1999061051A1 (en) | 1998-05-26 | 1999-05-26 | Compositions and methods of modulating an immune response to an antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE428441T1 true ATE428441T1 (de) | 2009-05-15 |
Family
ID=43124691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99930120T ATE428441T1 (de) | 1998-05-26 | 1999-05-26 | Zusammensetzungen und verfahren zur modulation einer immunantwort auf ein antigen durch verabreichung von zytokine-beladenen zellen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100297154A1 (de) |
| EP (1) | EP1079854B1 (de) |
| JP (1) | JP5546084B2 (de) |
| AT (1) | ATE428441T1 (de) |
| AU (1) | AU765529B2 (de) |
| CA (1) | CA2328604A1 (de) |
| DE (1) | DE69940731D1 (de) |
| ES (1) | ES2328194T3 (de) |
| IL (1) | IL139601A0 (de) |
| WO (1) | WO1999061051A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6756044B1 (en) | 2000-02-09 | 2004-06-29 | Genvec, Inc. | Antigenic complexes and methods |
| WO2001062901A2 (en) * | 2000-02-26 | 2001-08-30 | Artecel Sciences, Inc. | Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof |
| US7063845B2 (en) | 2000-04-28 | 2006-06-20 | Gemini Science, Inc. | Human anti-CD40 antibodies |
| AUPQ755300A0 (en) | 2000-05-17 | 2000-06-08 | Monash University | Immune potentiating compositions |
| PT1391464E (pt) | 2001-04-27 | 2007-11-15 | Kirin Pharma Kk | Anticorpo monoclonal anti-cd40 |
| JP4892705B2 (ja) * | 2002-08-20 | 2012-03-07 | オプサニテクス エルエルシー | レクチン組成物および抗原に対する免疫反応を調節するための方法 |
| US7629440B2 (en) * | 2002-08-20 | 2009-12-08 | Genitrix, Llc | Lectin compositions and methods for modulating an immune response to an antigen |
| US20040091503A1 (en) | 2002-08-20 | 2004-05-13 | Genitrix, Llc | Lectin compositions and methods for modulating an immune response to an antigen |
| TWI382843B (zh) | 2004-10-07 | 2013-01-21 | Argos Therapeutics Inc | 成熟樹突細胞組合物及培養彼等之方法 |
| US8513008B2 (en) | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| WO2009114085A2 (en) | 2008-03-03 | 2009-09-17 | The University Of Miami | Allogeneic cancer cell-based immunotherapy |
| US20140030212A1 (en) * | 2012-06-13 | 2014-01-30 | Incytu, Inc. | Compositions, methods and devices for activating an immune response |
| WO2015131176A1 (en) * | 2014-02-28 | 2015-09-03 | Podack Eckhard R | Compositions, methods, and kits for treatment of cancer |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US4736866A (en) | 1984-06-22 | 1988-04-12 | President And Fellows Of Harvard College | Transgenic non-human mammals |
| US5374548A (en) * | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| US5665383A (en) * | 1993-02-22 | 1997-09-09 | Vivorx Pharmaceuticals, Inc. | Methods for the preparation of immunostimulating agents for in vivo delivery |
| US5747024A (en) * | 1993-03-08 | 1998-05-05 | Immunex Corporation | Vaccine adjuvant comprising interleukin-15 |
| JP2000516911A (ja) * | 1996-03-28 | 2000-12-19 | ホワイトヘッド インスティテュート フォー バイオメディカル リサーチ | オプソニン強化細胞、および抗原に対する免疫応答を調節する方法 |
| US5837231A (en) * | 1996-06-27 | 1998-11-17 | Regents Of The University Of Minnesota | GM-CSF administration for the treatment and prevention of recurrence of brain tumors |
| US6017527A (en) * | 1996-07-10 | 2000-01-25 | Immunex Corporation | Activated dendritic cells and methods for their activation |
| US6491925B2 (en) * | 1996-08-15 | 2002-12-10 | Emory University | Compositions and methods for cancer prophylaxis and/or treatment |
| US5891432A (en) * | 1997-07-29 | 1999-04-06 | The Immune Response Corporation | Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same |
-
1999
- 1999-05-26 AT AT99930120T patent/ATE428441T1/de not_active IP Right Cessation
- 1999-05-26 ES ES99930120T patent/ES2328194T3/es not_active Expired - Lifetime
- 1999-05-26 DE DE69940731T patent/DE69940731D1/de not_active Expired - Lifetime
- 1999-05-26 EP EP99930120A patent/EP1079854B1/de not_active Expired - Lifetime
- 1999-05-26 AU AU46724/99A patent/AU765529B2/en not_active Ceased
- 1999-05-26 JP JP2000550510A patent/JP5546084B2/ja not_active Expired - Fee Related
- 1999-05-26 IL IL13960199A patent/IL139601A0/xx unknown
- 1999-05-26 WO PCT/US1999/011609 patent/WO1999061051A1/en not_active Ceased
- 1999-05-26 CA CA002328604A patent/CA2328604A1/en not_active Abandoned
-
2008
- 2008-05-08 US US12/151,908 patent/US20100297154A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP5546084B2 (ja) | 2014-07-09 |
| EP1079854A1 (de) | 2001-03-07 |
| WO1999061051A1 (en) | 1999-12-02 |
| EP1079854A4 (de) | 2004-08-25 |
| AU765529B2 (en) | 2003-09-18 |
| IL139601A0 (en) | 2002-02-10 |
| AU4672499A (en) | 1999-12-13 |
| US20100297154A1 (en) | 2010-11-25 |
| DE69940731D1 (de) | 2009-05-28 |
| EP1079854B1 (de) | 2009-04-15 |
| CA2328604A1 (en) | 1999-12-02 |
| ES2328194T3 (es) | 2009-11-10 |
| JP2002516290A (ja) | 2002-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |