ATE428441T1 - Zusammensetzungen und verfahren zur modulation einer immunantwort auf ein antigen durch verabreichung von zytokine-beladenen zellen - Google Patents
Zusammensetzungen und verfahren zur modulation einer immunantwort auf ein antigen durch verabreichung von zytokine-beladenen zellenInfo
- Publication number
- ATE428441T1 ATE428441T1 AT99930120T AT99930120T ATE428441T1 AT E428441 T1 ATE428441 T1 AT E428441T1 AT 99930120 T AT99930120 T AT 99930120T AT 99930120 T AT99930120 T AT 99930120T AT E428441 T1 ATE428441 T1 AT E428441T1
- Authority
- AT
- Austria
- Prior art keywords
- antigen
- cytokine
- modulating
- administration
- compositions
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000028993 immune response Effects 0.000 title 1
- 108010029697 CD40 Ligand Proteins 0.000 abstract 2
- 102100032937 CD40 ligand Human genes 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 101150013553 CD40 gene Proteins 0.000 abstract 1
- 102100040245 Tumor necrosis factor receptor superfamily member 5 Human genes 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001129—Molecules with a "CD" designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8678098P | 1998-05-26 | 1998-05-26 | |
| US9152598P | 1998-07-02 | 1998-07-02 | |
| PCT/US1999/011609 WO1999061051A1 (en) | 1998-05-26 | 1999-05-26 | Compositions and methods of modulating an immune response to an antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE428441T1 true ATE428441T1 (de) | 2009-05-15 |
Family
ID=43124691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99930120T ATE428441T1 (de) | 1998-05-26 | 1999-05-26 | Zusammensetzungen und verfahren zur modulation einer immunantwort auf ein antigen durch verabreichung von zytokine-beladenen zellen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100297154A1 (de) |
| EP (1) | EP1079854B1 (de) |
| JP (1) | JP5546084B2 (de) |
| AT (1) | ATE428441T1 (de) |
| AU (1) | AU765529B2 (de) |
| CA (1) | CA2328604A1 (de) |
| DE (1) | DE69940731D1 (de) |
| ES (1) | ES2328194T3 (de) |
| IL (1) | IL139601A0 (de) |
| WO (1) | WO1999061051A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6756044B1 (en) | 2000-02-09 | 2004-06-29 | Genvec, Inc. | Antigenic complexes and methods |
| PT1261694E (pt) * | 2000-02-26 | 2008-04-03 | Artecel Inc | Células estaminais pluripotentes produzidas a partir de células estromais derivadas de tecido adiposo e suas utilizações. |
| US7063845B2 (en) | 2000-04-28 | 2006-06-20 | Gemini Science, Inc. | Human anti-CD40 antibodies |
| AUPQ755300A0 (en) | 2000-05-17 | 2000-06-08 | Monash University | Immune potentiating compositions |
| EP2009027B1 (de) | 2001-04-27 | 2014-05-21 | Kyowa Hakko Kirin Co., Ltd. | Monoklonaler Antikörper gegen CD40 |
| US20040091503A1 (en) | 2002-08-20 | 2004-05-13 | Genitrix, Llc | Lectin compositions and methods for modulating an immune response to an antigen |
| MXPA05001953A (es) * | 2002-08-20 | 2005-06-22 | Genitrix Llc | Composiciones de lecitina y metodos para modular una respuesta inmune a un antigeno. |
| US7629440B2 (en) * | 2002-08-20 | 2009-12-08 | Genitrix, Llc | Lectin compositions and methods for modulating an immune response to an antigen |
| US8513008B2 (en) | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| AU2005294150B2 (en) | 2004-10-07 | 2011-06-16 | Coimmune, Inc. | Mature dendritic cell compositions and methods for culturing same |
| AU2009223838B2 (en) | 2008-03-03 | 2012-07-26 | The University Of Miami | Allogeneic cancer cell-based immunotherapy |
| CA2876143A1 (en) * | 2012-06-13 | 2013-12-19 | Incytu, Inc. | Compositions, methods and devices for activating an immune response |
| WO2015131176A1 (en) * | 2014-02-28 | 2015-09-03 | Podack Eckhard R | Compositions, methods, and kits for treatment of cancer |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US4736866A (en) | 1984-06-22 | 1988-04-12 | President And Fellows Of Harvard College | Transgenic non-human mammals |
| US5374548A (en) * | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| US5665383A (en) * | 1993-02-22 | 1997-09-09 | Vivorx Pharmaceuticals, Inc. | Methods for the preparation of immunostimulating agents for in vivo delivery |
| US5747024A (en) * | 1993-03-08 | 1998-05-05 | Immunex Corporation | Vaccine adjuvant comprising interleukin-15 |
| WO1997035619A1 (en) * | 1996-03-28 | 1997-10-02 | Genitrix, L.L.C. | Opsonin-enhanced cells, and methods of modulating an immune response to an antigen |
| US5837231A (en) * | 1996-06-27 | 1998-11-17 | Regents Of The University Of Minnesota | GM-CSF administration for the treatment and prevention of recurrence of brain tumors |
| US6017527A (en) * | 1996-07-10 | 2000-01-25 | Immunex Corporation | Activated dendritic cells and methods for their activation |
| US6491925B2 (en) * | 1996-08-15 | 2002-12-10 | Emory University | Compositions and methods for cancer prophylaxis and/or treatment |
| US5891432A (en) | 1997-07-29 | 1999-04-06 | The Immune Response Corporation | Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same |
-
1999
- 1999-05-26 JP JP2000550510A patent/JP5546084B2/ja not_active Expired - Fee Related
- 1999-05-26 AT AT99930120T patent/ATE428441T1/de not_active IP Right Cessation
- 1999-05-26 EP EP99930120A patent/EP1079854B1/de not_active Expired - Lifetime
- 1999-05-26 WO PCT/US1999/011609 patent/WO1999061051A1/en active IP Right Grant
- 1999-05-26 CA CA002328604A patent/CA2328604A1/en not_active Abandoned
- 1999-05-26 AU AU46724/99A patent/AU765529B2/en not_active Ceased
- 1999-05-26 DE DE69940731T patent/DE69940731D1/de not_active Expired - Lifetime
- 1999-05-26 IL IL13960199A patent/IL139601A0/xx unknown
- 1999-05-26 ES ES99930120T patent/ES2328194T3/es not_active Expired - Lifetime
-
2008
- 2008-05-08 US US12/151,908 patent/US20100297154A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999061051A1 (en) | 1999-12-02 |
| US20100297154A1 (en) | 2010-11-25 |
| IL139601A0 (en) | 2002-02-10 |
| EP1079854A4 (de) | 2004-08-25 |
| AU4672499A (en) | 1999-12-13 |
| JP5546084B2 (ja) | 2014-07-09 |
| AU765529B2 (en) | 2003-09-18 |
| CA2328604A1 (en) | 1999-12-02 |
| ES2328194T3 (es) | 2009-11-10 |
| EP1079854A1 (de) | 2001-03-07 |
| EP1079854B1 (de) | 2009-04-15 |
| DE69940731D1 (de) | 2009-05-28 |
| JP2002516290A (ja) | 2002-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |