ATE224867T1 - Verfahren zur herstellung von kontrastmitteln - Google Patents
Verfahren zur herstellung von kontrastmittelnInfo
- Publication number
- ATE224867T1 ATE224867T1 AT98914995T AT98914995T ATE224867T1 AT E224867 T1 ATE224867 T1 AT E224867T1 AT 98914995 T AT98914995 T AT 98914995T AT 98914995 T AT98914995 T AT 98914995T AT E224867 T1 ATE224867 T1 AT E224867T1
- Authority
- AT
- Austria
- Prior art keywords
- contrast agents
- producing contrast
- lanthanide
- producing
- metallation
- Prior art date
Links
- 239000002872 contrast media Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 abstract 3
- 229910052747 lanthanoid Inorganic materials 0.000 abstract 2
- 150000002602 lanthanoids Chemical class 0.000 abstract 2
- RZESKRXOCXWCFX-UHFFFAOYSA-N 2-[bis[2-[carboxymethyl-[2-(methylamino)-2-oxoethyl]amino]ethyl]amino]acetic acid Chemical compound CNC(=O)CN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC(=O)NC RZESKRXOCXWCFX-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000008139 complexing agent Substances 0.000 abstract 1
- 229910000311 lanthanide oxide Inorganic materials 0.000 abstract 1
- 238000006263 metalation reaction Methods 0.000 abstract 1
- 235000006408 oxalic acid Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Length Measuring Devices By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9707880.2A GB9707880D0 (en) | 1997-04-18 | 1997-04-18 | Contrast agent preparation |
| US4440997P | 1997-04-29 | 1997-04-29 | |
| PCT/GB1998/001019 WO1998047856A1 (en) | 1997-04-18 | 1998-04-07 | Contrast agent preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE224867T1 true ATE224867T1 (de) | 2002-10-15 |
Family
ID=26311410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98914995T ATE224867T1 (de) | 1997-04-18 | 1998-04-07 | Verfahren zur herstellung von kontrastmitteln |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6191262B1 (de) |
| EP (1) | EP0975580B1 (de) |
| JP (1) | JP4035625B2 (de) |
| CN (1) | CN100352802C (de) |
| AT (1) | ATE224867T1 (de) |
| AU (1) | AU745970B2 (de) |
| BR (1) | BR9808924A (de) |
| CA (1) | CA2287245A1 (de) |
| CZ (1) | CZ296233B6 (de) |
| DE (1) | DE69808265T2 (de) |
| ES (1) | ES2187018T3 (de) |
| GB (1) | GB9707880D0 (de) |
| HU (1) | HUP0001861A2 (de) |
| IL (1) | IL132433A0 (de) |
| NO (1) | NO320618B1 (de) |
| NZ (1) | NZ500061A (de) |
| PL (1) | PL336208A1 (de) |
| WO (1) | WO1998047856A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2794032B1 (fr) * | 1999-05-27 | 2002-06-14 | Univ Claude Bernard Lyon | Procede pour separer en milieu aqueux des lanthanides et/ou des actinides par complexation-nanofiltration, et nouveaux complexants mis en oeuvre dans ce procede |
| CN1321122C (zh) * | 2005-02-03 | 2007-06-13 | 华东师范大学 | 一种水热合成钆－二乙三胺五乙酸的方法 |
| EP2338874A1 (de) * | 2009-12-16 | 2011-06-29 | Bracco Imaging S.p.A | Verfahren zur Herstellung von chelatierten Verbindungen |
| CN106008254B (zh) * | 2016-05-27 | 2018-08-21 | 南京正大天晴制药有限公司 | 一种卡地酰胺钠的精制工艺 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
| FR2669028B1 (fr) * | 1990-11-13 | 1992-12-31 | Rhone Poulenc Chimie | Procede de fabrication d'oxalates doubles de terres rares et d'ammonium et leurs utilisations pour la fabrication d'oxydes de terres rares. |
| FR2674256B1 (fr) * | 1991-03-21 | 1994-07-29 | Commissariat Energie Atomique | Procede pour separer le fer et/ou le zirconium des actinides et/ou des lanthanides presents dans une solution aqueuse acide au moyen d'un propanediamide. |
-
1997
- 1997-04-18 GB GBGB9707880.2A patent/GB9707880D0/en active Pending
-
1998
- 1998-04-07 ES ES98914995T patent/ES2187018T3/es not_active Expired - Lifetime
- 1998-04-07 DE DE69808265T patent/DE69808265T2/de not_active Expired - Lifetime
- 1998-04-07 CN CNB988041316A patent/CN100352802C/zh not_active Expired - Lifetime
- 1998-04-07 EP EP98914995A patent/EP0975580B1/de not_active Expired - Lifetime
- 1998-04-07 AT AT98914995T patent/ATE224867T1/de not_active IP Right Cessation
- 1998-04-07 JP JP54526398A patent/JP4035625B2/ja not_active Expired - Lifetime
- 1998-04-07 CA CA002287245A patent/CA2287245A1/en not_active Abandoned
- 1998-04-07 BR BR9808924-2A patent/BR9808924A/pt unknown
- 1998-04-07 NZ NZ500061A patent/NZ500061A/en unknown
- 1998-04-07 PL PL98336208A patent/PL336208A1/xx unknown
- 1998-04-07 AU AU69287/98A patent/AU745970B2/en not_active Ceased
- 1998-04-07 WO PCT/GB1998/001019 patent/WO1998047856A1/en not_active Ceased
- 1998-04-07 IL IL13243398A patent/IL132433A0/xx unknown
- 1998-04-07 HU HU0001861A patent/HUP0001861A2/hu unknown
- 1998-04-07 CZ CZ0368899A patent/CZ296233B6/cs unknown
-
1999
- 1999-10-15 US US09/419,290 patent/US6191262B1/en not_active Expired - Lifetime
- 1999-10-15 NO NO19995058A patent/NO320618B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0975580B1 (de) | 2002-09-25 |
| AU6928798A (en) | 1998-11-13 |
| HUP0001861A2 (hu) | 2000-09-28 |
| WO1998047856A1 (en) | 1998-10-29 |
| DE69808265D1 (de) | 2002-10-31 |
| CA2287245A1 (en) | 1998-10-29 |
| NZ500061A (en) | 2001-04-27 |
| BR9808924A (pt) | 2000-08-01 |
| DE69808265T2 (de) | 2003-07-31 |
| CZ296233B6 (cs) | 2006-02-15 |
| IL132433A0 (en) | 2001-03-19 |
| CN100352802C (zh) | 2007-12-05 |
| AU745970B2 (en) | 2002-04-11 |
| PL336208A1 (en) | 2000-06-05 |
| CZ368899A3 (cs) | 2000-04-12 |
| US6191262B1 (en) | 2001-02-20 |
| NO320618B1 (no) | 2005-12-27 |
| ES2187018T3 (es) | 2003-05-16 |
| NO995058L (no) | 1999-10-15 |
| HK1025313A1 (en) | 2000-11-10 |
| EP0975580A1 (de) | 2000-02-02 |
| JP2001521545A (ja) | 2001-11-06 |
| GB9707880D0 (en) | 1997-06-04 |
| NO995058D0 (no) | 1999-10-15 |
| CN1252051A (zh) | 2000-05-03 |
| JP4035625B2 (ja) | 2008-01-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |