ATE424205T1 - Mittel zur behandlung des syndroms der unruhigen beine - Google Patents
Mittel zur behandlung des syndroms der unruhigen beineInfo
- Publication number
- ATE424205T1 ATE424205T1 AT02707244T AT02707244T ATE424205T1 AT E424205 T1 ATE424205 T1 AT E424205T1 AT 02707244 T AT02707244 T AT 02707244T AT 02707244 T AT02707244 T AT 02707244T AT E424205 T1 ATE424205 T1 AT E424205T1
- Authority
- AT
- Austria
- Prior art keywords
- legs syndrome
- restle
- treating
- medium
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Paper (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001100797 | 2001-03-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE424205T1 true ATE424205T1 (de) | 2009-03-15 |
Family
ID=18954209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02707244T ATE424205T1 (de) | 2001-03-30 | 2002-03-29 | Mittel zur behandlung des syndroms der unruhigen beine |
Country Status (12)
Country | Link |
---|---|
US (1) | US8338442B2 (de) |
EP (1) | EP1380306B1 (de) |
JP (1) | JP4453254B2 (de) |
KR (1) | KR100893328B1 (de) |
CN (1) | CN100398154C (de) |
AT (1) | ATE424205T1 (de) |
AU (1) | AU2002241326B2 (de) |
CA (1) | CA2442423C (de) |
DE (1) | DE60231388D1 (de) |
ES (1) | ES2319265T3 (de) |
PT (1) | PT1380306E (de) |
WO (1) | WO2002078744A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8062272B2 (en) | 2004-05-21 | 2011-11-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
US7909805B2 (en) | 2004-04-05 | 2011-03-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
CA2685126C (en) | 2007-04-24 | 2015-04-14 | Toray Industries, Inc. | Therapeutic or prophylactic agent for dyskinesia |
AU2008268202B2 (en) | 2007-06-22 | 2012-12-20 | Toray Industries, Inc. | Remedy or preventive for integration dysfunction syndrome |
BRPI0817804A8 (pt) | 2007-10-05 | 2017-04-18 | Toray Industries | Agente terapêutico para melhorar as propriedades da pele compreendendo um derivado de morfinano ou qualquer um de seus sais de adição de ácido farmacologicamente permissíveis como um ingrediente ativo |
AU2011211223B2 (en) * | 2010-01-29 | 2014-10-23 | Toray Industries, Inc. | Therapeutic or prophylactic agent for biliary diseases |
EP2630150B1 (de) * | 2010-10-19 | 2017-04-12 | Memorial Sloan-Kettering Cancer Center | 6-amido-derivat aus 4,5-a-epoxymorphinanen zur schmerzbehandlung |
MX2013008749A (es) | 2011-01-31 | 2013-10-17 | Toray Industries | Agente terapeutico o profilactico para caquexia. |
EP4212532A3 (de) | 2015-04-30 | 2023-09-27 | Memorial Sloan Kettering Cancer Center | Mitragynin-analoga und verwendungen davon |
EP3761982A4 (de) | 2018-03-08 | 2021-12-15 | Victoria Link Ltd | Behandlung von demyelinisierungskrankheiten |
IL309232A (en) | 2021-06-14 | 2024-02-01 | Scorpion Therapeutics Inc | History of urea which can be used to treat cancer |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA842753B (en) * | 1983-05-18 | 1984-11-28 | Upjohn Co | 2-dihydropyrrolyl-cycloalkyl-amide analgesics |
EP0232612B1 (de) | 1985-12-23 | 1990-04-04 | Dr. Lo. Zambeletti S.p.A. | Azacyclische Verbindungen, Verfahren zur ihrer Herstellung und ihre Verwendung als Pharmazeutika |
ES2039242T3 (es) | 1986-09-02 | 1993-09-16 | Dr. Lo. Zambeletti S.P.A. | Un procedimiento para la preparacion de nuevos derivados de piperidina. |
AU603850B2 (en) * | 1986-12-22 | 1990-11-29 | Dr. Lo Zambeletti S.P.A. | Novel piperidine derivatives |
GB9105152D0 (en) | 1991-03-12 | 1991-04-24 | Glaxo Group Ltd | Chemical compounds |
ES2121988T3 (es) * | 1992-01-23 | 1998-12-16 | Toray Industries | Derivado de morfinano y uso medicinal. |
JPH06122677A (ja) * | 1992-08-28 | 1994-05-06 | Sankyo Co Ltd | 光学活性なカルボン酸アミド誘導体 |
EP1327444B1 (de) | 1996-11-25 | 2005-03-23 | Toray Industries, Inc. | Mittel gegen Juckreiz |
EP0974363B1 (de) * | 1997-09-02 | 2005-06-22 | Toray Industries, Inc. | Heilmittel für die drogenabhängigkeit |
BR9908953A (pt) * | 1998-03-27 | 2000-12-05 | Upjohn Co | Utilização de cabergolina no tratamento da sìndrome de pernas agitadas (sìndrome de ekbom) |
SE9803760D0 (sv) * | 1998-11-04 | 1998-11-04 | Jan Hedner | Sätt att behandla och diagnostisera syndromet restless legs och motsvarande medel |
DE19938823A1 (de) * | 1999-08-19 | 2001-02-22 | Boehringer Ingelheim Pharma | Medikamentöse Behandlung des Restless Leg Syndroms |
-
2002
- 2002-03-29 PT PT02707244T patent/PT1380306E/pt unknown
- 2002-03-29 ES ES02707244T patent/ES2319265T3/es not_active Expired - Lifetime
- 2002-03-29 AT AT02707244T patent/ATE424205T1/de active
- 2002-03-29 AU AU2002241326A patent/AU2002241326B2/en not_active Expired
- 2002-03-29 CA CA002442423A patent/CA2442423C/en not_active Expired - Lifetime
- 2002-03-29 US US10/473,541 patent/US8338442B2/en active Active
- 2002-03-29 KR KR1020037011641A patent/KR100893328B1/ko active IP Right Grant
- 2002-03-29 EP EP02707244A patent/EP1380306B1/de not_active Expired - Lifetime
- 2002-03-29 JP JP2002586270A patent/JP4453254B2/ja not_active Expired - Fee Related
- 2002-03-29 WO PCT/JP2002/003156 patent/WO2002078744A1/ja active Application Filing
- 2002-03-29 CN CNB02807257XA patent/CN100398154C/zh not_active Expired - Lifetime
- 2002-03-29 DE DE60231388T patent/DE60231388D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2442423A1 (en) | 2002-10-10 |
PT1380306E (pt) | 2009-05-25 |
CA2442423C (en) | 2009-11-03 |
KR20030086288A (ko) | 2003-11-07 |
US8338442B2 (en) | 2012-12-25 |
WO2002078744A1 (fr) | 2002-10-10 |
JP4453254B2 (ja) | 2010-04-21 |
CN100398154C (zh) | 2008-07-02 |
JPWO2002078744A1 (ja) | 2004-07-22 |
DE60231388D1 (de) | 2009-04-16 |
EP1380306A4 (de) | 2005-06-08 |
CN1537016A (zh) | 2004-10-13 |
EP1380306A1 (de) | 2004-01-14 |
KR100893328B1 (ko) | 2009-04-14 |
ES2319265T3 (es) | 2009-05-06 |
EP1380306B1 (de) | 2009-03-04 |
US20040116456A1 (en) | 2004-06-17 |
AU2002241326B2 (en) | 2007-09-06 |
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Legal Events
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