ATE422365T1 - Verfahren zur auslösung einer zytotoxischen immunantwort und dafür nützliche rekombinante affen-adenovirus-zusammensetzungen - Google Patents

Verfahren zur auslösung einer zytotoxischen immunantwort und dafür nützliche rekombinante affen-adenovirus-zusammensetzungen

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Publication number
ATE422365T1
ATE422365T1 AT02780874T AT02780874T ATE422365T1 AT E422365 T1 ATE422365 T1 AT E422365T1 AT 02780874 T AT02780874 T AT 02780874T AT 02780874 T AT02780874 T AT 02780874T AT E422365 T1 ATE422365 T1 AT E422365T1
Authority
AT
Austria
Prior art keywords
triggering
immune response
cytotoxic immune
monkey adenovirus
useful recombinant
Prior art date
Application number
AT02780874T
Other languages
English (en)
Inventor
Hildegund Ertl
James Wilson
Original Assignee
Wistar Inst
Univ Pennsylvania
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Publication date
Application filed by Wistar Inst, Univ Pennsylvania filed Critical Wistar Inst
Application granted granted Critical
Publication of ATE422365T1 publication Critical patent/ATE422365T1/de

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/235—Adenoviridae
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
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    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/55—Vector systems having a special element relevant for transcription from bacteria
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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AT02780874T 2001-06-22 2002-05-13 Verfahren zur auslösung einer zytotoxischen immunantwort und dafür nützliche rekombinante affen-adenovirus-zusammensetzungen ATE422365T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30013101P 2001-06-22 2001-06-22
US30484301P 2001-07-12 2001-07-12

Publications (1)

Publication Number Publication Date
ATE422365T1 true ATE422365T1 (de) 2009-02-15

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AT02780874T ATE422365T1 (de) 2001-06-22 2002-05-13 Verfahren zur auslösung einer zytotoxischen immunantwort und dafür nützliche rekombinante affen-adenovirus-zusammensetzungen

Country Status (26)

Country Link
US (1) US20040241181A1 (de)
EP (1) EP1409012B1 (de)
JP (1) JP2005523233A (de)
KR (1) KR20040043129A (de)
CN (1) CN1518457A (de)
AT (1) ATE422365T1 (de)
AU (1) AU2002308713B2 (de)
BR (1) BR0210586A (de)
CA (1) CA2451864C (de)
CY (1) CY1109059T1 (de)
CZ (1) CZ304169B6 (de)
DE (1) DE60231123D1 (de)
DK (1) DK1409012T3 (de)
ES (1) ES2322043T3 (de)
HK (1) HK1061511A1 (de)
HU (1) HU228327B1 (de)
IL (2) IL159454A0 (de)
MX (1) MXPA04000024A (de)
NO (1) NO333252B1 (de)
NZ (1) NZ530245A (de)
PL (1) PL216200B1 (de)
PT (1) PT1409012E (de)
SG (1) SG153649A1 (de)
SI (1) SI1409012T1 (de)
WO (1) WO2003000283A1 (de)
ZA (1) ZA200309360B (de)

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CN103468743B (zh) * 2013-08-19 2015-07-29 中国科学院上海巴斯德研究所 一种狂犬病疫苗及其制备方法
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US11254711B2 (en) 2015-06-12 2022-02-22 Glaxosmithkline Biologicals Sa Adenovirus polynucleotides and polypeptides
MX2019002178A (es) 2016-08-23 2019-09-18 Glaxosmithkline Biologicals Sa Peptidos de fusion con antigenos enlazados a fragmentos cortos de cadena invariante (cd74).
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EP1409012A4 (de) 2005-08-03
PL372294A1 (en) 2005-07-11
NO20035740D0 (no) 2003-12-19
DE60231123D1 (de) 2009-03-26
PT1409012E (pt) 2009-05-11
HUP0400297A3 (en) 2010-08-30
PL216200B1 (pl) 2014-03-31
SG153649A1 (en) 2009-07-29
EP1409012A1 (de) 2004-04-21
NO333252B1 (no) 2013-04-22
CZ20033438A3 (cs) 2004-04-14
DK1409012T3 (da) 2009-05-18
CY1109059T1 (el) 2014-07-02
ES2322043T3 (es) 2009-06-16
EP1409012B1 (de) 2009-02-11
CN1518457A (zh) 2004-08-04
MXPA04000024A (es) 2004-05-21
HUP0400297A2 (en) 2007-05-02
NO20035740L (no) 2004-02-16
CA2451864A1 (en) 2003-01-03
IL159454A (en) 2009-09-01
BR0210586A (pt) 2005-07-12
KR20040043129A (ko) 2004-05-22
WO2003000283A1 (en) 2003-01-03
JP2005523233A (ja) 2005-08-04
CZ304169B6 (cs) 2013-12-04
CA2451864C (en) 2013-01-15
US20040241181A1 (en) 2004-12-02
AU2002308713B2 (en) 2008-05-15
ZA200309360B (en) 2005-07-27
HU228327B1 (en) 2013-03-28
SI1409012T1 (sl) 2009-08-31
HK1061511A1 (en) 2004-09-24
AU2002308713A2 (en) 2003-01-08
IL159454A0 (en) 2004-06-01
NZ530245A (en) 2007-04-27

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