ATE421576T1 - Verfahren zur herstellung rekombinanter adenoviraler viren mittels stellenspezifischer rekombination - Google Patents

Verfahren zur herstellung rekombinanter adenoviraler viren mittels stellenspezifischer rekombination

Info

Publication number
ATE421576T1
ATE421576T1 AT03708709T AT03708709T ATE421576T1 AT E421576 T1 ATE421576 T1 AT E421576T1 AT 03708709 T AT03708709 T AT 03708709T AT 03708709 T AT03708709 T AT 03708709T AT E421576 T1 ATE421576 T1 AT E421576T1
Authority
AT
Austria
Prior art keywords
site
specific recombination
present
producing recombinant
recombinant viruses
Prior art date
Application number
AT03708709T
Other languages
German (de)
English (en)
Inventor
Ho-Sun Son
Neon-C Jung
Dong-Seung Seen
Kyung-Jin Kim
Sung-Eun Cho
Eun-Wook Choi
Original Assignee
Newgex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newgex Inc filed Critical Newgex Inc
Application granted granted Critical
Publication of ATE421576T1 publication Critical patent/ATE421576T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/38—Vector systems having a special element relevant for transcription being a stuffer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
AT03708709T 2002-03-09 2003-03-08 Verfahren zur herstellung rekombinanter adenoviraler viren mittels stellenspezifischer rekombination ATE421576T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20020012633 2002-03-09

Publications (1)

Publication Number Publication Date
ATE421576T1 true ATE421576T1 (de) 2009-02-15

Family

ID=27800659

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03708709T ATE421576T1 (de) 2002-03-09 2003-03-08 Verfahren zur herstellung rekombinanter adenoviraler viren mittels stellenspezifischer rekombination

Country Status (9)

Country Link
US (1) US20040005710A1 (ko)
EP (1) EP1483375B1 (ko)
JP (2) JP4558328B2 (ko)
KR (1) KR100631428B1 (ko)
CN (1) CN100532545C (ko)
AT (1) ATE421576T1 (ko)
AU (1) AU2003212687A1 (ko)
DE (1) DE60325942D1 (ko)
WO (1) WO2003076605A1 (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0424356D0 (en) * 2004-11-03 2004-12-08 Ark Therapeutics Ltd Baculovirus-based gene libraries
WO2007132169A1 (en) * 2006-05-11 2007-11-22 Crusade Laboratories Limited Mutant hsv, materials and methods for generation of mutant hsv
US9127312B2 (en) 2011-02-09 2015-09-08 Bio-Rad Laboratories, Inc. Analysis of nucleic acids
CN103237889B (zh) * 2010-08-16 2017-04-05 萨克生物研究学院 腺病毒组装方法
KR101416600B1 (ko) * 2012-08-17 2014-07-08 (주)프로스테믹스 친수성 분리막을 이용하여 아데노바이러스 ｄｎａ-말단 단백질 복합체를 분리하는 방법
JP6576326B2 (ja) 2013-03-14 2019-09-18 ソーク インスティテュート フォー バイオロジカル スタディーズ 腫瘍溶解性アデノウイルス組成物
EP3024948B1 (en) 2013-07-25 2020-01-15 Bio-rad Laboratories, Inc. Genetic assays for detecting viral recombination rate
WO2016081567A1 (en) * 2014-11-19 2016-05-26 Orlo James Fiske Thin optical system and camera
AU2017223589B2 (en) 2016-02-23 2023-08-03 Salk Institute For Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
CA3013637A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
WO2018111767A1 (en) 2016-12-12 2018-06-21 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
CN114457098B (zh) * 2022-01-07 2022-12-27 广东省农业科学院蔬菜研究所 一种多基因载体系统及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143557A (en) * 1995-06-07 2000-11-07 Life Technologies, Inc. Recombination cloning using engineered recombination sites
CN100342008C (zh) * 1997-10-24 2007-10-10 茵维特罗根公司 利用具重组位点的核酸进行重组克隆
AU785483B2 (en) * 1999-12-10 2007-09-20 Invitrogen Corporation Use of multiple recombination sites with unique specificity in recombinational cloning

Also Published As

Publication number Publication date
AU2003212687A1 (en) 2003-09-22
US20040005710A1 (en) 2004-01-08
CN100532545C (zh) 2009-08-26
KR100631428B1 (ko) 2006-10-11
CN1639325A (zh) 2005-07-13
EP1483375A4 (en) 2005-08-10
WO2003076605A1 (en) 2003-09-18
DE60325942D1 (de) 2009-03-12
JP4558328B2 (ja) 2010-10-06
EP1483375B1 (en) 2009-01-21
EP1483375A1 (en) 2004-12-08
JP2010193896A (ja) 2010-09-09
KR20040111390A (ko) 2004-12-31
JP2005519603A (ja) 2005-07-07

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