ATE420086T1 - Chinolinthiazolinone mit cdk-1 antiproliferativer wirkung - Google Patents

Chinolinthiazolinone mit cdk-1 antiproliferativer wirkung

Info

Publication number
ATE420086T1
ATE420086T1 AT05745044T AT05745044T ATE420086T1 AT E420086 T1 ATE420086 T1 AT E420086T1 AT 05745044 T AT05745044 T AT 05745044T AT 05745044 T AT05745044 T AT 05745044T AT E420086 T1 ATE420086 T1 AT E420086T1
Authority
AT
Austria
Prior art keywords
quinolinthiazolinone
cdk
antiproliferative effect
antiproliferative
effect
Prior art date
Application number
AT05745044T
Other languages
English (en)
Inventor
Li Chen
Shaoqing Chen
Christophe Michoud
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE420086T1 publication Critical patent/ATE420086T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT05745044T 2004-07-01 2005-06-23 Chinolinthiazolinone mit cdk-1 antiproliferativer wirkung ATE420086T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58493104P 2004-07-01 2004-07-01
US65827305P 2005-03-03 2005-03-03

Publications (1)

Publication Number Publication Date
ATE420086T1 true ATE420086T1 (de) 2009-01-15

Family

ID=34971310

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05745044T ATE420086T1 (de) 2004-07-01 2005-06-23 Chinolinthiazolinone mit cdk-1 antiproliferativer wirkung

Country Status (18)

Country Link
US (1) US7250515B2 (de)
EP (1) EP1771443B1 (de)
JP (1) JP2008504323A (de)
KR (1) KR100856363B1 (de)
CN (1) CN1976927A (de)
AR (1) AR049539A1 (de)
AT (1) ATE420086T1 (de)
AU (1) AU2005259511A1 (de)
BR (1) BRPI0512843A (de)
CA (1) CA2571732A1 (de)
DE (1) DE602005012273D1 (de)
ES (1) ES2317238T3 (de)
IL (1) IL180097A0 (de)
MX (1) MXPA06015026A (de)
NO (1) NO20070565L (de)
RU (1) RU2007103706A (de)
TW (1) TW200610764A (de)
WO (1) WO2006002828A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008545690A (ja) * 2005-05-23 2008-12-18 スミスクライン・ビーチャム・コーポレイション 新規化合物
MX2007014929A (es) * 2005-06-02 2008-02-15 Hoffmann La Roche 3-metansulfonilquinolinas como mejoradores de gaba-b.
PE20070083A1 (es) * 2005-06-08 2007-01-27 Smithkline Beecham Corp (5z)-5-(6-quinoxalinilmetilideno)-2-[(2,6-diclorofenil)amino]-1,3-tiazol-4(5h)-ona
CL2007000995A1 (es) * 2006-04-11 2008-06-27 Smithkline Beecham Corp Compuestos derivados de tiazolidinadiona; composicion farmaceutica; y uso para tratar uno o mas estados de enfermedad seleccionada entre trastornos autoinmunes, enfermedad inflamatoria, cardiovascular y neurodegenerativa entre otras.
US20100286041A1 (en) * 2007-03-22 2010-11-11 Smithkline Beecham Corporation (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one
US20080255115A1 (en) * 2007-04-11 2008-10-16 Michael Gerard Darcy Thiazolidinedione derivatives as pi3 kinase inhibitors
US7592342B2 (en) * 2007-05-10 2009-09-22 Smithkline Beecham Corporation Quinoxaline derivatives as PI3 kinase inhibitors
PE20090717A1 (es) * 2007-05-18 2009-07-18 Smithkline Beecham Corp Derivados de quinolina como inhibidores de la pi3 quinasa
CN107098898B (zh) * 2016-02-19 2020-01-07 湖南大学 氮杂环氨基噻唑甲基喹啉酮衍生物及其制备方法与应用
AR124154A1 (es) 2020-11-27 2023-02-22 Rhizen Pharmaceuticals Ag Inhibidores de cdk
WO2022149057A1 (en) 2021-01-05 2022-07-14 Rhizen Pharmaceuticals Ag Cdk inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1215208B1 (de) * 1997-10-27 2006-07-12 Agouron Pharmaceuticals, Inc. 4-Aminothiazol Derivate, deren Herstellung und deren Verwendung als Inhibitoren Cyclin-abhängiger Kinasen
EP1567112B1 (de) * 2002-11-22 2008-10-15 Smithkline Beecham Corporation THIAZOLIDIN-4-ONES UM hYAK3 PROTEINEN ZU HEMMEN

Also Published As

Publication number Publication date
BRPI0512843A (pt) 2008-04-08
AR049539A1 (es) 2006-08-09
NO20070565L (no) 2007-02-08
KR100856363B1 (ko) 2008-09-04
AU2005259511A1 (en) 2006-01-12
US20060004046A1 (en) 2006-01-05
US7250515B2 (en) 2007-07-31
CN1976927A (zh) 2007-06-06
EP1771443A1 (de) 2007-04-11
CA2571732A1 (en) 2006-01-12
JP2008504323A (ja) 2008-02-14
EP1771443B1 (de) 2009-01-07
KR20070027656A (ko) 2007-03-09
MXPA06015026A (es) 2007-02-08
RU2007103706A (ru) 2008-08-10
TW200610764A (en) 2006-04-01
ES2317238T3 (es) 2009-04-16
IL180097A0 (en) 2007-05-15
WO2006002828A1 (en) 2006-01-12
DE602005012273D1 (de) 2009-02-26

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