NO20070565L - Kinolin tiazolinoner med CDK1 antiproliferativ aktivitet - Google Patents

Kinolin tiazolinoner med CDK1 antiproliferativ aktivitet

Info

Publication number
NO20070565L
NO20070565L NO20070565A NO20070565A NO20070565L NO 20070565 L NO20070565 L NO 20070565L NO 20070565 A NO20070565 A NO 20070565A NO 20070565 A NO20070565 A NO 20070565A NO 20070565 L NO20070565 L NO 20070565L
Authority
NO
Norway
Prior art keywords
quinoline
antiproliferative activity
thiazolinones
cdk1
cdk1 antiproliferative
Prior art date
Application number
NO20070565A
Other languages
English (en)
Norwegian (no)
Inventor
Shaoqing Chen
Li Chen
Christophe Michoud
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20070565L publication Critical patent/NO20070565L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20070565A 2004-07-01 2007-01-30 Kinolin tiazolinoner med CDK1 antiproliferativ aktivitet NO20070565L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58493104P 2004-07-01 2004-07-01
US65827305P 2005-03-03 2005-03-03
PCT/EP2005/006806 WO2006002828A1 (en) 2004-07-01 2005-06-23 Quinoline thiazolinones with cdk1 antiproliferative activity

Publications (1)

Publication Number Publication Date
NO20070565L true NO20070565L (no) 2007-02-08

Family

ID=34971310

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070565A NO20070565L (no) 2004-07-01 2007-01-30 Kinolin tiazolinoner med CDK1 antiproliferativ aktivitet

Country Status (18)

Country Link
US (1) US7250515B2 (de)
EP (1) EP1771443B1 (de)
JP (1) JP2008504323A (de)
KR (1) KR100856363B1 (de)
CN (1) CN1976927A (de)
AR (1) AR049539A1 (de)
AT (1) ATE420086T1 (de)
AU (1) AU2005259511A1 (de)
BR (1) BRPI0512843A (de)
CA (1) CA2571732A1 (de)
DE (1) DE602005012273D1 (de)
ES (1) ES2317238T3 (de)
IL (1) IL180097A0 (de)
MX (1) MXPA06015026A (de)
NO (1) NO20070565L (de)
RU (1) RU2007103706A (de)
TW (1) TW200610764A (de)
WO (1) WO2006002828A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1885362A4 (de) * 2005-05-23 2010-09-22 Glaxosmithkline Llc Neue chemische verbindungen
EP1893560A2 (de) * 2005-06-02 2008-03-05 F. Hoffmann-Roche AG 3-methansulfonylchinoline als gaba-b-enhancer
TW200716580A (en) * 2005-06-08 2007-05-01 Smithkline Beecham Corp (5Z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one
CL2007000995A1 (es) * 2006-04-11 2008-06-27 Smithkline Beecham Corp Compuestos derivados de tiazolidinadiona; composicion farmaceutica; y uso para tratar uno o mas estados de enfermedad seleccionada entre trastornos autoinmunes, enfermedad inflamatoria, cardiovascular y neurodegenerativa entre otras.
US20100286041A1 (en) * 2007-03-22 2010-11-11 Smithkline Beecham Corporation (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one
US20080255115A1 (en) * 2007-04-11 2008-10-16 Michael Gerard Darcy Thiazolidinedione derivatives as pi3 kinase inhibitors
CL2008001356A1 (es) * 2007-05-10 2008-11-14 Smithkline Beecham Corp Compuestos derivados de quinoxalina, inhibidores de la pi3 quinasa _(p13ka, pi3ko, pi3b y/o pi3ky); composicion farmaceutica; uso para tratar un trastorno autoinmune, enfermedad inflamatoria, cardiovascular, neurodegerativa, alergia, asma, enfermedad renal, cancer, rechazo de transplante, lesiones pulmonares.
PE20090717A1 (es) 2007-05-18 2009-07-18 Smithkline Beecham Corp Derivados de quinolina como inhibidores de la pi3 quinasa
CN107098898B (zh) * 2016-02-19 2020-01-07 湖南大学 氮杂环氨基噻唑甲基喹啉酮衍生物及其制备方法与应用
AR124154A1 (es) 2020-11-27 2023-02-22 Rhizen Pharmaceuticals Ag Inhibidores de cdk
WO2022149057A1 (en) 2021-01-05 2022-07-14 Rhizen Pharmaceuticals Ag Cdk inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1215208B1 (de) * 1997-10-27 2006-07-12 Agouron Pharmaceuticals, Inc. 4-Aminothiazol Derivate, deren Herstellung und deren Verwendung als Inhibitoren Cyclin-abhängiger Kinasen
DK1567112T3 (da) * 2002-11-22 2009-02-09 Smithkline Beecham Corp Thiazolidin-4-oner til at hæmme hYAK3-proteiner

Also Published As

Publication number Publication date
MXPA06015026A (es) 2007-02-08
CA2571732A1 (en) 2006-01-12
KR20070027656A (ko) 2007-03-09
CN1976927A (zh) 2007-06-06
ES2317238T3 (es) 2009-04-16
KR100856363B1 (ko) 2008-09-04
WO2006002828A1 (en) 2006-01-12
US20060004046A1 (en) 2006-01-05
IL180097A0 (en) 2007-05-15
AR049539A1 (es) 2006-08-09
TW200610764A (en) 2006-04-01
RU2007103706A (ru) 2008-08-10
DE602005012273D1 (de) 2009-02-26
AU2005259511A1 (en) 2006-01-12
BRPI0512843A (pt) 2008-04-08
EP1771443A1 (de) 2007-04-11
ATE420086T1 (de) 2009-01-15
EP1771443B1 (de) 2009-01-07
US7250515B2 (en) 2007-07-31
JP2008504323A (ja) 2008-02-14

Similar Documents

Publication Publication Date Title
NO20070565L (no) Kinolin tiazolinoner med CDK1 antiproliferativ aktivitet
SG170785A1 (en) Benzothiazoles having histamine h3 receptor activity
NO20093200L (no) Tiazolidinderivater
NO20043176L (no) Nikotinamidderivater nyttige som P38 inhibitorer
NO20051165L (no) Benzotiazolderivater som har -adrenoerseptorantagonist aktivitet
NO20091893L (no) Nye 1,4-benzotiepin-1,1-dioksidderivater som er substituert med benzylgrupper, fremgangsmater for fremstilling av medisiner inneholdende forbindelsene og anvendelse derav.
NO20060110L (no) Spesifik glukokortikosteroid forbindelse med anti-inflammatorisk aktivitet
NO20064282L (no) Morfolinforbindelser
NO20061978L (no) Imidazopyridinsubstituerte tropanderivater med CCR5-reseptorantagonist aktivitet for behandling av HIV og inflammasjon
NO20070526L (no) Kinazolindionderivater som parp-inhibitorer
NO20050870L (no) Fosfodiesterase 4-inhibitorer, inkludert N-substituerte anilin- og difenylaminanaloger
NO20070555L (no) Kinazolinonderivater som parp-inhibitorer
NO20071137L (no) Nye piperidinderivater for behandling av depresjon
NO20070564L (no) Kinoliner uten tiazolinonsubstituenter.
NO20082389L (no) 2,3,4-trifenylimidazolinderivater som inhibitor av interaksjonen mellom P53- og MDM2-proteiner for anvendelse som antikreftmidler
NO20073663L (no) Tiazol-4-karboksamid-derivater som mGluR5 antagonister
EA200701122A1 (ru) Потенциаторы рецепторов глутамата
CY1112886T1 (el) Ανοσοκατασταλτικος παραγοντας ο οποιος περιλαμβανει μια ετεροκυκλικη ενωση ως δραστικο συστατικο
ATE302775T1 (de) Carbolinderivate
ATE413392T1 (de) Kondensierte heteroyralderivate und deren verwendung als p38-kinase-inhibitoren
NO20064415L (no) Nye amido-substituerte hydroksy-6-fenylfenantridiner og deres anvendelse som PDE4-inhibitorer
ATE346067T1 (de) Carbolinderivate
NO20045045L (no) Anionisk viskoelastisk overflateaktivt middel
AR045959A1 (es) Derivados de pirazolo- e imidazo-pirimidina
BR0313385A (pt) Derivados de pirimidina-2,4-diona como inibidores de metaloproteinase da matriz

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application