ATE419022T1 - Hydrophobe mehrkomponenten-heparinkonjugate, ein verfahren zur ihrer herstellung und verwendung - Google Patents

Hydrophobe mehrkomponenten-heparinkonjugate, ein verfahren zur ihrer herstellung und verwendung

Info

Publication number
ATE419022T1
ATE419022T1 AT00973237T AT00973237T ATE419022T1 AT E419022 T1 ATE419022 T1 AT E419022T1 AT 00973237 T AT00973237 T AT 00973237T AT 00973237 T AT00973237 T AT 00973237T AT E419022 T1 ATE419022 T1 AT E419022T1
Authority
AT
Austria
Prior art keywords
heparin conjugates
hydrophobic
production
present
conjugates
Prior art date
Application number
AT00973237T
Other languages
English (en)
Inventor
Young Ro Byun
Hyun Tae Moon
Original Assignee
Mediplex Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediplex Corp Korea filed Critical Mediplex Corp Korea
Application granted granted Critical
Publication of ATE419022T1 publication Critical patent/ATE419022T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0081—Reaction with amino acids, peptides, or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT00973237T 2000-10-24 2000-11-03 Hydrophobe mehrkomponenten-heparinkonjugate, ein verfahren zur ihrer herstellung und verwendung ATE419022T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR10-2000-0062668A KR100378109B1 (ko) 2000-10-24 2000-10-24 소수성 다중복합 헤파린 결합체, 그의 제조방법 및 용도

Publications (1)

Publication Number Publication Date
ATE419022T1 true ATE419022T1 (de) 2009-01-15

Family

ID=19695171

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00973237T ATE419022T1 (de) 2000-10-24 2000-11-03 Hydrophobe mehrkomponenten-heparinkonjugate, ein verfahren zur ihrer herstellung und verwendung

Country Status (9)

Country Link
US (1) US7129224B1 (de)
EP (1) EP1333871B1 (de)
JP (1) JP3927118B2 (de)
KR (1) KR100378109B1 (de)
CN (1) CN1209171C (de)
AT (1) ATE419022T1 (de)
AU (1) AU2001211769A1 (de)
DE (1) DE60041283D1 (de)
WO (1) WO2002034312A1 (de)

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US7438925B2 (en) * 2002-08-26 2008-10-21 Biovention Holdings Ltd. Drug eluting coatings for medical implants
US6702850B1 (en) * 2002-09-30 2004-03-09 Mediplex Corporation Korea Multi-coated drug-eluting stent for antithrombosis and antirestenosis
US8293890B2 (en) 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
US7563780B1 (en) * 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
WO2006067959A1 (ja) 2004-12-21 2006-06-29 Shinshu University 医療機器
ES2376888T3 (es) 2005-05-04 2012-03-20 Suprapolix B.V. Materiales supramoleculares activos biológicamente, modulares biorreabsorbibles o biomédicos
ATE527305T1 (de) 2006-11-20 2011-10-15 Suprapolix Bv Supramolekulare polymere aus niedrigschmelzenden, leicht verarbeitbaren bausteinen
US20090281059A1 (en) * 2007-02-21 2009-11-12 Robert Falotico Coating for a medical device having an anti-thrombotic conjugate
US20080200421A1 (en) * 2007-02-21 2008-08-21 Zhao Jonathon Z Coating for a medical device having an anti-thrombotic conjugate
US8628789B2 (en) 2007-03-23 2014-01-14 Suprapolix, B.V. Strong reversible hydrogels
WO2008122034A1 (en) 2007-04-02 2008-10-09 Ension, Inc. Process for preparing a substrate coated with a biomolecule
US9693841B2 (en) 2007-04-02 2017-07-04 Ension, Inc. Surface treated staples, sutures and dental floss and methods of manufacturing the same
US8383156B2 (en) 2007-04-30 2013-02-26 Cordis Corporation Coating for a medical device having an anti-thrombotic conjugate
EP2173359A2 (de) * 2007-06-29 2010-04-14 Mediplex Corp. Heparin-konjugate und verfahren
US8088753B2 (en) * 2007-06-29 2012-01-03 Mediplex Corporation, Korea Heparin conjugates and methods
US20090018646A1 (en) 2007-07-10 2009-01-15 Zhao Jonathon Z Coating Employing an Anti-Thrombotic Conjugate
US20100021538A1 (en) * 2008-02-29 2010-01-28 Youngro Byun Pharmaceutical compositions containing heparin derivatives
WO2010002262A1 (en) 2008-07-04 2010-01-07 Suprapolix B.V. High flow supramolecular compounds
GB201004101D0 (en) 2010-03-12 2010-04-28 Carmeda Ab Immobilised biological entities
WO2012050630A1 (en) * 2010-10-14 2012-04-19 Medtronic, Inc. Cannular device and method of manufacture
EP2450394B1 (de) 2010-11-05 2017-06-07 SupraPolix B.V. Verfahren zur Herstellung eines supramolekularen Polymers
EP3699220A1 (de) * 2013-04-26 2020-08-26 Biointeractions Ltd Bioaktive beschichtungen
CN105228665A (zh) * 2013-05-20 2016-01-06 耶鲁大学 抗血栓形成移植物
US9339770B2 (en) 2013-11-19 2016-05-17 Applied Membrane Technologies, Inc. Organosiloxane films for gas separations
KR101881541B1 (ko) * 2016-07-25 2018-07-24 가톨릭대학교산학협력단 골형성 또는 골 유착능 향상을 위한 생분해성 고분자의 표면처리 방법
CN106986955B (zh) * 2017-04-28 2019-04-09 华南理工大学 一种肝素的叠氮化修饰方法和叠氮化肝素及应用
CN109925536B (zh) * 2017-12-15 2021-01-26 先健科技(深圳)有限公司 可吸收铁基植入式器械
TWI653993B (zh) 2018-03-20 2019-03-21 國立臺灣大學 血管取代物
CN115990297B (zh) * 2023-03-09 2023-11-07 上海宏普医疗器械有限公司 一种基于ptfe材料的肝素抗凝涂层及其制备方法

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JPS5357288A (en) * 1976-11-04 1978-05-24 Nippon Zeon Co Ltd Anticoagulant medical polymer its preparation and use
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US6702850B1 (en) * 2002-09-30 2004-03-09 Mediplex Corporation Korea Multi-coated drug-eluting stent for antithrombosis and antirestenosis

Also Published As

Publication number Publication date
EP1333871A4 (de) 2004-07-07
EP1333871B1 (de) 2008-12-31
AU2001211769A1 (en) 2002-05-06
US7129224B1 (en) 2006-10-31
CN1209171C (zh) 2005-07-06
CN1455687A (zh) 2003-11-12
JP3927118B2 (ja) 2007-06-06
JP2004512397A (ja) 2004-04-22
EP1333871A1 (de) 2003-08-13
DE60041283D1 (de) 2009-02-12
KR100378109B1 (ko) 2003-03-29
WO2002034312A1 (en) 2002-05-02
KR20020031894A (ko) 2002-05-03

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