ATE532540T1 - Modulare bioresorbierbare oder biomedizinische biologisch aktive supramolekulare stoffe - Google Patents

Modulare bioresorbierbare oder biomedizinische biologisch aktive supramolekulare stoffe

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Publication number
ATE532540T1
ATE532540T1 AT06733084T AT06733084T ATE532540T1 AT E532540 T1 ATE532540 T1 AT E532540T1 AT 06733084 T AT06733084 T AT 06733084T AT 06733084 T AT06733084 T AT 06733084T AT E532540 T1 ATE532540 T1 AT E532540T1
Authority
AT
Austria
Prior art keywords
biomedical
bioresorbable
modular
biologically active
supramolecular
Prior art date
Application number
AT06733084T
Other languages
English (en)
Inventor
Patricia Dankers
Gemert Gaby Hoorne-Van
Henricus Janssen
Egbert Meijer
Anton Bosman
Original Assignee
Suprapolix Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suprapolix Bv filed Critical Suprapolix Bv
Application granted granted Critical
Publication of ATE532540T1 publication Critical patent/ATE532540T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
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    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
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    • A61L31/10—Macromolecular materials
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    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
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    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/16—Catalysts
    • C08G18/22—Catalysts containing metal compounds
    • C08G18/24—Catalysts containing metal compounds of tin
    • C08G18/244—Catalysts containing metal compounds of tin tin salts of carboxylic acids
    • C08G18/246—Catalysts containing metal compounds of tin tin salts of carboxylic acids containing also tin-carbon bonds
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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    • C08G18/38—Low-molecular-weight compounds having heteroatoms other than oxygen
    • C08G18/3819—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen
    • C08G18/3842—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen containing heterocyclic rings having at least one nitrogen atom in the ring
    • C08G18/3848—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen containing heterocyclic rings having at least one nitrogen atom in the ring containing two nitrogen atoms in the ring
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    • C08G18/40—High-molecular-weight compounds
    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4202—Two or more polyesters of different physical or chemical nature
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4236—Polycondensates having carboxylic or carbonic ester groups in the main chain containing only aliphatic groups
    • C08G18/4238—Polycondensates having carboxylic or carbonic ester groups in the main chain containing only aliphatic groups derived from dicarboxylic acids and dialcohols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
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    • C08G18/4266—Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
    • C08G18/4269—Lactones
    • C08G18/4277—Caprolactone and/or substituted caprolactone
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    • C08G18/40—High-molecular-weight compounds
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    • C08G18/67—Unsaturated compounds having active hydrogen
    • C08G18/671—Unsaturated compounds having only one group containing active hydrogen
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
AT06733084T 2005-05-04 2006-05-03 Modulare bioresorbierbare oder biomedizinische biologisch aktive supramolekulare stoffe ATE532540T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05103764 2005-05-04
US67967105P 2005-05-11 2005-05-11
EP05111018 2005-11-21
PCT/NL2006/050107 WO2006118461A2 (en) 2005-05-04 2006-05-03 Modular bioresorbable or biomedical, biologically active supramolecular materials

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Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1687378T3 (en) 2003-11-04 2014-03-03 Suprapolix Bv Preparation of supramolecular polymers containing four hydrogen bonding units in the polymer backbone
EP1773903B1 (de) 2004-07-12 2017-08-09 SupraPolix B.V. Supramolekulare ionomere
EP1877113B1 (de) 2005-05-04 2011-11-09 SupraPolix B.V. Modulare bioresorbierbare oder biomedizinische biologisch aktive supramolekulare stoffe
US20100076147A1 (en) * 2006-11-20 2010-03-25 Suprapolix B.V. Supramolecular polymers from low-melting, easily processable building blocks
US8628789B2 (en) 2007-03-23 2014-01-14 Suprapolix, B.V. Strong reversible hydrogels
ATE515538T1 (de) * 2007-03-23 2011-07-15 Suprapolix Bv Starke umkehrbare hydrogels
US8754213B2 (en) 2008-07-04 2014-06-17 Suprapolix B.V. High flow supramolecular compounds
US8822610B2 (en) 2008-12-22 2014-09-02 ATRP Solutions, Inc. Control over controlled radical polymerization processes
US8815971B2 (en) * 2008-12-22 2014-08-26 ATRP Solutions, Inc. Control over controlled radical polymerization processes
US8569421B2 (en) 2009-04-23 2013-10-29 ATRP Solutions, Inc. Star macromolecules for personal and home care
US9783628B2 (en) 2009-04-23 2017-10-10 ATRP Solutions, Inc. Dual-mechanism thickening agents for hydraulic fracturing fluids
US8173750B2 (en) 2009-04-23 2012-05-08 ATRP Solutions, Inc. Star macromolecules for personal and home care
FR2954907B1 (fr) 2010-01-04 2012-02-24 Oreal Composition cosmetique, procede de traitement cosmetique et kit
FR2954908B1 (fr) * 2010-01-05 2016-07-01 Oreal Procedes de traitement cosmetique et kit
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
US9006386B2 (en) 2010-11-05 2015-04-14 Suprapolix B.V. Process for the preparation of a supramolecular polymer
ES2590983T3 (es) 2010-12-03 2016-11-24 Xeltis B.V. Uso de un polímero fluorado como agente de contraste para formación de imágenes por resonancia magnética (IRM) 19F en estado sólido, andamiaje que comprende dicho polímero y uso del mismo
US9587064B2 (en) 2010-12-08 2017-03-07 ATRP Solutions, Inc. Salt-tolerant star macromolecules
FR2968956B1 (fr) * 2010-12-15 2012-12-14 Oreal Composition cosmetique comprenant un compose supramoleculaire hydrocarbone a, un compose supramoleculaire silicone b, et au moins une matiere colorante
US8487017B2 (en) 2011-06-27 2013-07-16 Covidien Lp Biodegradable materials for orthopedic devices based on polymer stereocomplexes
NL2009145C2 (en) * 2012-07-06 2014-01-07 Xeltis B V Implant.
JP6294885B2 (ja) 2012-08-30 2018-03-14 エーティーアールピー ソリューションズ インコーポレイテッドＡＴＲＰ Ｓｏｌｕｔｉｏｎｓ，Ｉｎｃ． 星形高分子、星形高分子組成物および星形高分子の製造方法
CA2899349C (en) 2013-02-04 2021-09-21 ATRP Solutions, Inc. Salt-tolerant star macromolecules
US20140234435A1 (en) 2013-02-20 2014-08-21 Bone Support Ab Setting of hardenable bone substitute
EP2997076B1 (de) * 2013-05-14 2022-03-16 SupraPolix B.V. Supramolekulares biologisch abbaubares polymer
DE102014226785B4 (de) * 2013-12-27 2019-08-14 Asahi Kasei Chemicals Corporation Polycarbonatdiolzusammensetzung, Beschichtungszusammensetzung und Verwendung der Polycarbonatdiolzusammensetzung
MX385886B (es) 2014-07-03 2025-03-18 Pilot Polymer Tech Inc Macromoleculas estrellas compatibles con tensoactivos.
US10358521B2 (en) 2014-07-28 2019-07-23 Suprapolix B.V. Durable hydrogen bonded hydrogels
CN104399131B (zh) * 2014-10-21 2016-04-27 赵红斌 具有组织诱导性功能的多通道神经修复导管及模具
EP3277745B1 (de) * 2015-04-02 2024-11-27 The Regents of The University of Michigan Selbstintegrierende hydrogele und verfahren zur herstellung davon
KR101747534B1 (ko) 2015-10-02 2017-06-16 숭실대학교산학협력단 열-가역 네트워크 구조를 기반으로 한 fdm 3d 프린팅용 초분자형 조성물
EP3389853B1 (de) 2015-12-18 2023-10-18 University of Canterbury Trennmedium
KR101937314B1 (ko) * 2016-12-30 2019-01-10 롯데첨단소재(주) 고무 공중합체 및 이를 포함하는 열가소성 수지 조성물
JP6972152B2 (ja) * 2017-03-31 2021-11-24 ゼルティス ベーフェー 心血管移植片
NL2019957B1 (en) * 2017-11-22 2019-05-29 Suprapolix Bv Supramolecular biomedical polymers
US10953139B2 (en) * 2017-12-28 2021-03-23 Xeltis Ag Electro-spun cardiovascular implant
US11376113B2 (en) 2018-08-16 2022-07-05 Cook Medical Technologies Llc Graft material and method of use thereof
US11439495B2 (en) 2018-08-22 2022-09-13 Cook Medical Technologies Llc Self-healing graft material and method of use thereof
CN109369541A (zh) * 2018-10-12 2019-02-22 常州大学 一种邻苯二酚醚链桥连双脲基嘧啶酮化合物及其合成方法
CN110627993B (zh) * 2019-10-22 2021-09-21 华南理工大学 一种含四重氢键的水性聚氨酯分散体及其制备方法
CN114886945B (zh) * 2022-05-10 2023-07-07 西安外事学院 一种调节嘌呤代谢的超分子药物及其应用

Family Cites Families (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE639107A (de) 1962-10-26
BE640789A (de) 1962-12-05
US3375800A (en) 1967-04-07 1968-04-02 Jimmy R. Cole Seismic cable depth control apparatus
JPS4829398B1 (de) 1968-08-28 1973-09-10
US4093759A (en) 1972-12-23 1978-06-06 Toyo Ink Manufacturing Co., Ltd. Glass container coated with polyurethane
JPS5122823A (ja) 1974-08-21 1976-02-23 Nissan Chemical Ind Ltd Noengeiyokoirusuzai
US4136092A (en) 1975-06-09 1979-01-23 Thiokol Corporation Polyurethane curing agents
JPS5274692A (en) 1975-12-19 1977-06-22 Toyo Soda Mfg Co Ltd Process for preparing poly (quaternay ammonium salt) containing two or more kinds of nucleic acid bases
US4216318A (en) 1975-12-29 1980-08-05 Smith Kline & French Laboratories Limited Heterocyclic alkyl 4-pyrimidones
JPS5413694A (en) 1977-07-01 1979-02-01 Sumitomo Electric Industries Composite blood vessel prosthesis and method of producing same
US4140759A (en) * 1977-07-13 1979-02-20 Helena Rubinstein, Inc. Protein shampoo
US4684728A (en) 1979-01-12 1987-08-04 Bayer Aktiengesellschaft Solubilizing biologically active compounds with reactive hydrogen atoms
SU910718A1 (ru) 1979-03-05 1982-03-07 Институт химии высокомолекулярных соединений АН УССР Клеева композици
DE2938309A1 (de) 1979-09-21 1981-04-09 Chemische Werke Hüls AG, 4370 Marl Verfahren zum beschichten von glasoberflaechen sowie mit einer duroplastischen schutzschicht bezogene glasgegenstaende
US4322327A (en) 1979-10-19 1982-03-30 Mitsubishi Petrochemical Co., Ltd. Slow-curing water-curable urethane prepolymer composition
DE3378250D1 (en) 1982-04-22 1988-11-24 Ici Plc Continuous release formulations
US4499233A (en) 1983-05-03 1985-02-12 Nl Industries, Inc. Water dispersible, modified polyurethane and a thickened aqueous composition containing it
JPH0829398B2 (ja) 1986-10-22 1996-03-27 昭和電工株式会社 金属の水平連続鋳造法及び装置
EP0400015A4 (en) 1987-12-02 1991-01-16 Tyndale Plains-Hunter, Ltd. Hydrophilic polyurethanes of improved strength
FR2655651B1 (fr) 1989-12-13 1992-03-20 Rhone Poulenc Chimie Associations polymoleculaires eventuellement thermotropes dont les monomeres de base sont lies entre eux par des liaisons hydrogene, un procede servant a les preparer et les monomeres de base destines a la mise en óoeuvre de ce procede.
FR2657082B1 (fr) 1990-01-18 1992-05-22 Rhone Poulenc Chimie Associations polymoleculaires non-centrosymetriques et leurs utilisations notamment en optique non lineaire.
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5610268A (en) 1992-01-13 1997-03-11 Dsm N.V. Dendritic macromolecule and the preparation thereof
CA2133657A1 (en) 1992-04-16 1993-10-28 Peter R. Bernstein Substituted derivatives
US5399706A (en) 1993-03-02 1995-03-21 H. B. Fuller Licensing & Financing, Inc. Imidazolidinone diamine and derivatives thereof
KR0148704B1 (ko) 1994-01-10 1998-08-17 김상응 생체분해성 약물전달용 고분자
US5500209A (en) 1994-03-17 1996-03-19 The Mennen Company Deodorant and antiperspirant compositions containing polyamide gelling agent
GB9511758D0 (en) 1995-05-26 1995-08-02 Kodak Ltd Polymers and products derived therefrom
US5631337A (en) 1996-01-19 1997-05-20 Soane Bioscience Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis
US5883211A (en) 1996-01-19 1999-03-16 Aclara Biosciences, Inc. Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis
US5874069A (en) 1997-01-24 1999-02-23 Colgate-Palmolive Company Cosmetic composition containing silicon-modified amides as thickening agents and method of forming same
US5919441A (en) 1996-04-01 1999-07-06 Colgate-Palmolive Company Cosmetic composition containing thickening agent of siloxane polymer with hydrogen-bonding groups
ES2175369T3 (es) 1996-10-01 2002-11-16 Celanese Ventures Gmbh Proceso para producir peliculas polimeras para uso como pilas de combustible.
NL1004192C2 (nl) 1996-10-04 1998-04-07 Dsm Nv Supramoleculair polymeer.
US5723563A (en) 1996-10-11 1998-03-03 Arco Chemical Technology, L.P. Spandex elastomers
US5741881A (en) 1996-11-25 1998-04-21 Meadox Medicals, Inc. Process for preparing covalently bound-heparin containing polyurethane-peo-heparin coating compositions
JP2972861B2 (ja) 1997-05-08 1999-11-08 北陸先端科学技術大学院大学長 超分子構造の血液適合性材料
US6051216A (en) 1997-08-01 2000-04-18 Colgate-Palmolive Company Cosmetic composition containing siloxane based polyamides as thickening agents
KR20010022708A (ko) 1997-08-08 2001-03-26 프레드한 아룬디프 에스 약물 수송에 이용할 수 있는 생분해가능한 주사용 블록공중합체 겔
DE19741716A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Adressierbares modulares Erkennungssystem, seine Herstellung und Verwendung
AU9597198A (en) 1997-10-03 1999-04-27 Galenica Pharmaceuticals, Inc. Imine-forming polysaccharides, preparation thereof and the use thereof as adjuvants and immunostimulants
DE19821732A1 (de) 1998-05-14 1999-11-18 Basf Ag Vernetzte, wasserlösliche oder wasserdispergierbare Polyurethane
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
NL1011386C2 (nl) 1999-02-25 2000-08-28 Dsm Nv Supramoleculaire verbinding.
JP2003516810A (ja) 1999-11-15 2003-05-20 バイオキュア・インコーポレーテッド 分解性ポリ（ビニルアルコール）ヒドロゲル
US6719987B2 (en) * 2000-04-17 2004-04-13 Nucryst Pharmaceuticals Corp. Antimicrobial bioabsorbable materials
FR2808679B1 (fr) 2000-05-09 2006-09-22 Oreal Procede pour accroitre la persistance d'au moins un effet cosmetique et/ou de soin d'une composition cosmetique, composition cosmetique et son utilisation
EP1213309A1 (de) 2000-12-05 2002-06-12 Huntsman International Llc Polymer, das ein supramolekulares Polymer formt
KR100378109B1 (ko) 2000-10-24 2003-03-29 주식회사 메디프렉스 소수성 다중복합 헤파린 결합체, 그의 제조방법 및 용도
US6506536B2 (en) 2000-12-29 2003-01-14 Kodak Polychrome Graphics, Llc Imageable element and composition comprising thermally reversible polymers
US6913765B2 (en) * 2001-03-21 2005-07-05 Scimed Life Systems, Inc. Controlling resorption of bioresorbable medical implant material
ATE278760T1 (de) 2001-05-17 2004-10-15 Unilever Nv Waschmittelzusammensetzung
FR2825628B1 (fr) * 2001-06-07 2004-03-19 Oreal Composition cosmetique comportant un polymere comprenant des groupes de jonction capables d'etablir chacun au moins trois liaisons h
US20030158403A1 (en) 2001-07-03 2003-08-21 Isis Pharmaceuticals, Inc. Nuclease resistant chimeric oligonucleotides
US20030015185A1 (en) 2001-07-18 2003-01-23 Dutart Charles H. Intake air separation system for an internal combustion engine
US6716370B2 (en) 2001-07-25 2004-04-06 The Boeing Company Supramolecular oxo-anion corrosion inhibitors
US6972304B2 (en) 2001-09-07 2005-12-06 Xerox Corporation Aqueous ink compositions
FR2830256A1 (fr) 2001-10-03 2003-04-04 Nexans Composition polymere supramoleculaire, ainsi que son procede de fabrication et cable comportant une telle composition
JP2003180820A (ja) * 2001-10-09 2003-07-02 Techno Network Shikoku Co Ltd 生体材料、医薬品、食品、医療用具、細胞培養器具および組織誘導材料の製造方法
GB0124967D0 (en) * 2001-10-17 2001-12-05 Unilever Plc Cosmetic and personal care compositions
EP1310533B2 (de) 2001-10-25 2011-07-27 Agfa Graphics N.V. Tintenzusammensetzung enthaltend einen besonderen Farbstoff und Tintenstrahldruckverfahren unter Verwendung derselben
JP4554929B2 (ja) 2001-11-29 2010-09-29 ユニバーシティ・オブ・サザン・カリフォルニア マグネシウムで媒介されたフッ素化アルキルシランの調製
DE60304992T2 (de) 2002-01-17 2007-01-18 Arkema France Supramolekularpolymere
US6939938B2 (en) 2002-01-21 2005-09-06 L'oreal S.A. Amphiphilic cationic associative polymers, preparation process, use as thickeners and composition comprising them
DE60313606T2 (de) 2002-05-27 2008-01-03 Huntsman International Llc, Salt Lake City Expandierte supramolekulare polymere
US20040023155A1 (en) 2002-08-01 2004-02-05 Eiji Hayakawa Composition for a thermal lithographic printing plate and lithographic printing plate comprising the composition
US6803447B2 (en) * 2002-08-16 2004-10-12 Eutechpark Mmp1.28 Preparation of supramolecular polymers by copolymerization of monomers containing quadruple hydrogen bonding units with regular monomers
US6702850B1 (en) 2002-09-30 2004-03-09 Mediplex Corporation Korea Multi-coated drug-eluting stent for antithrombosis and antirestenosis
US6899992B2 (en) 2002-11-08 2005-05-31 Kodak Polychrome Graphics Llc Polymerizable compounds with quadruple hydrogen bond forming groups
WO2004052963A1 (en) 2002-12-09 2004-06-24 Suprapolix B.V. Siloxane polymers with quadruple hydrogen bonding units
JP2004250623A (ja) 2003-02-21 2004-09-09 Toray Ind Inc ポリエステル樹脂、その製造方法および成形品
DK1687378T3 (en) 2003-11-04 2014-03-03 Suprapolix Bv Preparation of supramolecular polymers containing four hydrogen bonding units in the polymer backbone
EP1773903B1 (de) 2004-07-12 2017-08-09 SupraPolix B.V. Supramolekulare ionomere
JP2008540725A (ja) 2005-05-04 2008-11-20 スープラポリックス ビー．ブイ． 水素結合ヒドロゲル
EP1877113B1 (de) 2005-05-04 2011-11-09 SupraPolix B.V. Modulare bioresorbierbare oder biomedizinische biologisch aktive supramolekulare stoffe
WO2007058539A2 (en) 2005-11-21 2007-05-24 Suprapolix B.V. Modular supramolecular materials for biomedical uses
FR2894816B1 (fr) 2005-12-16 2008-02-01 Oreal Composition cosmetique ou pharmaceutique comprenant un copolymere comportant au moins un groupe ionisable, et procede de traitement cosmetique
GB0525970D0 (en) 2005-12-21 2006-02-01 Secr Defence Supramolecular polymers
US20100076147A1 (en) 2006-11-20 2010-03-25 Suprapolix B.V. Supramolecular polymers from low-melting, easily processable building blocks
US8628789B2 (en) 2007-03-23 2014-01-14 Suprapolix, B.V. Strong reversible hydrogels
NL2001766C2 (nl) 2008-07-04 2010-01-05 Thomas Regout Internat B V Schuifgeleiding en een armsteun voorzien van een dergelijke schuifgeleiding.
US8754213B2 (en) 2008-07-04 2014-06-17 Suprapolix B.V. High flow supramolecular compounds
US9006386B2 (en) 2010-11-05 2015-04-14 Suprapolix B.V. Process for the preparation of a supramolecular polymer

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EP1877113B1 (de) 2011-11-09
WO2006118461A2 (en) 2006-11-09
ES2376888T3 (es) 2012-03-20
US20150057237A1 (en) 2015-02-26
US9339586B2 (en) 2016-05-17
US20160228229A1 (en) 2016-08-11
US8883188B2 (en) 2014-11-11
WO2006118461A3 (en) 2007-10-04
JP5130201B2 (ja) 2013-01-30
JP2008539859A (ja) 2008-11-20
US9907637B2 (en) 2018-03-06
US20090130172A1 (en) 2009-05-21
EP1877113A2 (de) 2008-01-16

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