ATE418327T1 - Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung - Google Patents

Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung

Info

Publication number
ATE418327T1
ATE418327T1 AT03743276T AT03743276T ATE418327T1 AT E418327 T1 ATE418327 T1 AT E418327T1 AT 03743276 T AT03743276 T AT 03743276T AT 03743276 T AT03743276 T AT 03743276T AT E418327 T1 ATE418327 T1 AT E418327T1
Authority
AT
Austria
Prior art keywords
production
continuous process
immediate release
release pharmaceutical
granular compositions
Prior art date
Application number
AT03743276T
Other languages
English (en)
Inventor
Jean-Paul Remon
Kris Vervaet
Original Assignee
Univ Gent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Gent filed Critical Univ Gent
Application granted granted Critical
Publication of ATE418327T1 publication Critical patent/ATE418327T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03743276T 2002-03-06 2003-03-05 Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung ATE418327T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0205253.8A GB0205253D0 (en) 2002-03-06 2002-03-06 Immediate release pharmaceutical granule compositions and a continuous process for making them

Publications (1)

Publication Number Publication Date
ATE418327T1 true ATE418327T1 (de) 2009-01-15

Family

ID=9932403

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03743276T ATE418327T1 (de) 2002-03-06 2003-03-05 Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung

Country Status (22)

Country Link
US (4) US20050058705A1 (de)
EP (1) EP1480622B1 (de)
KR (1) KR20040091099A (de)
CN (1) CN1638738B (de)
AR (1) AR038880A1 (de)
AT (1) ATE418327T1 (de)
AU (1) AU2003215449B2 (de)
BR (1) BR0308231A (de)
CA (1) CA2477890C (de)
DE (1) DE60325461D1 (de)
DK (1) DK1480622T3 (de)
ES (1) ES2318147T3 (de)
GB (1) GB0205253D0 (de)
HK (1) HK1078006A1 (de)
MX (1) MXPA04008543A (de)
MY (1) MY138752A (de)
PL (1) PL208133B1 (de)
PT (1) PT1480622E (de)
SA (1) SA03240089B1 (de)
TW (1) TWI296198B (de)
WO (1) WO2003074031A1 (de)
ZA (1) ZA200407998B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0205253D0 (en) 2002-03-06 2002-04-17 Univ Gent Immediate release pharmaceutical granule compositions and a continuous process for making them
NZ544007A (en) * 2003-05-07 2009-05-31 Samyang Corp Highly plastic granules for making fast melting tablets
US8025899B2 (en) * 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US7888412B2 (en) 2004-03-26 2011-02-15 Board Of Trustees Of The University Of Alabama Polymer dissolution and blend formation in ionic liquids
US7550520B2 (en) 2005-05-31 2009-06-23 The University Of Alabama Method of preparing high orientation nanoparticle-containing sheets or films using ionic liquids, and the sheets or films produced thereby
US8883193B2 (en) 2005-06-29 2014-11-11 The University Of Alabama Cellulosic biocomposites as molecular scaffolds for nano-architectures
EP1745775B1 (de) * 2005-07-19 2008-05-28 Ethypharm Gastroretentive Zusammensetzungen und Verfahren zur Herstellung
GB0612695D0 (en) * 2006-06-27 2006-08-09 Univ Gent Process for preparing a solid dosage form
US20100038816A1 (en) 2006-08-16 2010-02-18 Novartis Ag Method of making solid dispersions of highly crystalline therapeutic compounds
WO2008021666A2 (en) * 2006-08-18 2008-02-21 Morton Grove Pharmaceuticals, Inc. Stable liquid levetiracetam compositions and methods
KR20090090387A (ko) * 2006-12-19 2009-08-25 쉐링-프라우 리미티드 음료수 시스템 내에 추가하기 위한 플로르페니콜의 비등성 제형
BRPI0810601A2 (pt) * 2007-04-27 2014-10-21 Schering Plough Ltd Compostos e métodos para aumento da solubilidade de florfenicol e antibióticos estruturalmente relacionados usando ciclodextrinas
WO2009105236A1 (en) 2008-02-19 2009-08-27 The Board Of Trustees Of The University Of Alabama Ionic liquid systems for the processing of biomass, their components and/or derivatives, and mixtures thereof
JP5519639B2 (ja) * 2008-04-28 2014-06-11 フォーマック ファーマシューティカルズ ナムローゼ フェンノートシャップ 秩序化したメソポーラスシリカ材料
FR2935084B1 (fr) * 2008-08-19 2011-05-06 Pancosma Sa Pour L Ind Des Produits Biochimiques Additif pour l'alimentation animale et son procede de preparation
US9278134B2 (en) 2008-12-29 2016-03-08 The Board Of Trustees Of The University Of Alabama Dual functioning ionic liquids and salts thereof
WO2010141470A2 (en) 2009-06-01 2010-12-09 The Board Of Trustees Of The University Of Alabama Process for forming films, fibers, and beads from chitinous biomass
WO2011011322A1 (en) 2009-07-24 2011-01-27 The Board Of Trustees Of The University Of Alabama Conductive composites prepared using ionic liquids
BRPI1002023A2 (pt) 2010-03-01 2011-10-25 Nanocore Biotecnologia S A forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
CN101843586B (zh) * 2010-04-29 2012-05-23 山东迅达康兽药有限公司 一种含有氟苯尼考的可溶于水的微粉及其制备方法
CN102178068B (zh) * 2010-07-06 2013-07-31 新疆农业大学 一种饲料添加剂的使用方法
US9394375B2 (en) 2011-03-25 2016-07-19 Board Of Trustees Of The University Of Alabama Compositions containing recyclable ionic liquids for use in biomass processing
JP6154803B2 (ja) * 2011-05-02 2017-06-28 アデア ファーマスーティカルズ,インコーポレイテッド 膣投与のための迅速溶解性錠剤組成物
EP2537518A1 (de) * 2011-06-24 2012-12-26 Elanco Animal Health Ireland Limited Schnell zerfallendene Azaperon-Granulatformulierungen
WO2014106962A1 (ko) 2013-01-07 2014-07-10 삼아제약 주식회사 향상된 용해도를 갖는 신규한 속용성 과립제형
BR102013020508B1 (pt) * 2013-08-12 2021-01-12 Ems S/A. Forma de dosagem que compreende um inibidor de esteroide 5-alfa-redutase e um bloqueador alfa, processo para a preparaçãode uma forma de dosagem e uso da forma de dosagem
US10100131B2 (en) 2014-08-27 2018-10-16 The Board Of Trustees Of The University Of Alabama Chemical pulping of chitinous biomass for chitin
US10011931B2 (en) 2014-10-06 2018-07-03 Natural Fiber Welding, Inc. Methods, processes, and apparatuses for producing dyed and welded substrates
US10982381B2 (en) 2014-10-06 2021-04-20 Natural Fiber Welding, Inc. Methods, processes, and apparatuses for producing welded substrates
HUE062147T2 (hu) 2015-02-17 2023-10-28 Univ Gent Ivóvízbe keverhetõ gyógyszerként való felhasználásra alkalmas szilárd gyógyszerészeti dózisforma
EP3423063A4 (de) * 2016-03-04 2019-11-06 Embera Neurotherapeutics, Inc Zusammensetzungen und verfahren zur behandlung von sucht oder substanzmissbrauchsstörungen
US11766835B2 (en) 2016-03-25 2023-09-26 Natural Fiber Welding, Inc. Methods, processes, and apparatuses for producing welded substrates
CA3021729A1 (en) 2016-05-03 2017-11-09 Natural Fiber Welding, Inc. Methods, processes, and apparatuses for producing dyed and welded substrates
CN108210501B (zh) * 2016-12-14 2019-03-08 中国人民解放军军事医学科学院毒物药物研究所 一种磺酰脲类药物的注射用药物组合物及其制备方法
US10927191B2 (en) 2017-01-06 2021-02-23 The Board Of Trustees Of The University Of Alabama Coagulation of chitin from ionic liquid solutions using kosmotropic salts
CN110582278B (zh) 2017-03-10 2023-04-18 伊姆贝拉神经疗法公司 药物组合物及其用途
US10941258B2 (en) 2017-03-24 2021-03-09 The Board Of Trustees Of The University Of Alabama Metal particle-chitin composite materials and methods of making thereof
JP2021536485A (ja) * 2018-09-06 2021-12-27 イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド 注射可能な徐放性の抗生物質製剤
CN114532451B (zh) * 2022-02-28 2023-06-02 安徽科技学院 一种促进肉羊育肥的中药组方添加剂及制备方法
CN116019771A (zh) * 2022-09-09 2023-04-28 沈阳伟嘉生物技术有限公司 一种氟苯尼考可混饮无定形固体分散体制剂及其制备方法和用途

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639637A (en) * 1968-04-23 1972-02-01 Richardson Merrell Inc Water dispersible diethylstilbestrol compositions
US4235892A (en) * 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
GB2166436B (en) * 1984-09-14 1989-05-24 Glaxo Group Ltd Antibiotic compounds and their preparation
DE3440288A1 (de) * 1984-11-05 1986-05-07 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische zubereitung mit einem gehalt an mindestens einer schleimhautreizenden substanz oder dergleichen, insbesondere profen, sowie verfahren zu ihrer herstellung
IT1187751B (it) * 1985-10-15 1987-12-23 Eurand Spa Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute
FR2634376B1 (fr) 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
GB8913889D0 (en) 1989-06-16 1989-08-02 May & Baker Ltd New compositions of matter
IT1246188B (it) * 1990-07-27 1994-11-16 Resa Farma Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
US5082863A (en) * 1990-08-29 1992-01-21 Schering Corporation Pharmaceutical composition of florfenicol
AU671811B2 (en) * 1991-12-18 1996-09-12 Warner-Lambert Company A process for the preparation of a solid dispersion
US5362860A (en) * 1993-02-01 1994-11-08 Warner-Lambert Company Neutral stabilization complex for CI-979 HCl, a cognition activator
BE1006990A5 (nl) * 1993-04-22 1995-02-07 Univ Gent Werkwijze en samenstelling om een aktief bestanddeel in een vaste toedieningsvorm te brengen.
US5646131A (en) * 1994-02-22 1997-07-08 The Arab Company For Drug Industries And Medical Applicances (Acdima) Method for solubilizing drugs using cyclodextrins and carboxylic acids
HN1998000115A (es) * 1997-08-21 1999-06-02 Warner Lambert Co Formas de dosificación farmacéuticas sólidas
US6153206A (en) * 1997-08-27 2000-11-28 Revlon Consumer Products Corporation Cosmetic compositions
ATE252892T1 (de) 1997-09-11 2003-11-15 Nycomed Danmark Aps Aus mehreren einzeleinheiten zusammengesetzte arzneimittel mit nicht-steroidalen wirkstoffen (nsaids)
US6010719A (en) * 1997-09-16 2000-01-04 Universiteit Gent Freeze-dried disintegrating tablets
US6211185B1 (en) * 1999-05-05 2001-04-03 Veterinary Pharmacy Corporation Concentrate comprising a sulfonamide in solution, a 2,4-diaminopyrimidine in stable suspension within said solution, and a suspending agent
US20010046526A1 (en) * 2000-04-19 2001-11-29 C-Quest Treatment of fungal infections
AU2001257511A1 (en) * 2000-05-03 2001-11-12 Joe D'silva Process and device for producing liquid dosage formulations
AU2002212200A1 (en) * 2000-08-31 2002-03-13 Universiteit Gent Controlled release pharmaceutical pellet compositions for reducing side effects of drugs
US6663897B2 (en) * 2001-02-06 2003-12-16 Dsm Ip Assets B.V. Oral itraconazole formulations and methods of making the same
KR20040079967A (ko) * 2002-02-01 2004-09-16 화이자 프로덕츠 인크. 고체 약물 분산액을 함유하는 속방형 제형
GB0205253D0 (en) * 2002-03-06 2002-04-17 Univ Gent Immediate release pharmaceutical granule compositions and a continuous process for making them

Also Published As

Publication number Publication date
DE60325461D1 (de) 2009-02-05
PT1480622E (pt) 2009-03-06
WO2003074031A1 (en) 2003-09-12
CA2477890C (en) 2011-05-10
TW200305446A (en) 2003-11-01
MY138752A (en) 2009-07-31
BR0308231A (pt) 2004-12-28
MXPA04008543A (es) 2004-12-06
EP1480622B1 (de) 2008-12-24
US20110027377A1 (en) 2011-02-03
HK1078006A1 (en) 2006-03-03
PL208133B1 (pl) 2011-03-31
US8349366B2 (en) 2013-01-08
KR20040091099A (ko) 2004-10-27
GB0205253D0 (en) 2002-04-17
AU2003215449B2 (en) 2007-07-26
CA2477890A1 (en) 2003-09-12
ZA200407998B (en) 2006-06-28
AU2003215449A1 (en) 2003-09-16
US20050058705A1 (en) 2005-03-17
US8337897B2 (en) 2012-12-25
TWI296198B (en) 2008-05-01
SA03240089B1 (ar) 2008-07-12
EP1480622A1 (de) 2004-12-01
CN1638738A (zh) 2005-07-13
CN1638738B (zh) 2012-06-06
DK1480622T3 (da) 2009-02-16
US20070009592A1 (en) 2007-01-11
US20110008454A1 (en) 2011-01-13
PL372579A1 (en) 2005-07-25
ES2318147T3 (es) 2009-05-01
AR038880A1 (es) 2005-02-02

Similar Documents

Publication Publication Date Title
ATE418327T1 (de) Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung
ATE344034T1 (de) N-adamantylmethyl-derivate und zwischenprodukte als pharmazeutische zusammensetzungen und verfahren zu ihrer herstellung
ATE252562T1 (de) Pyrazolcarbonsäurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE422154T1 (de) Im mund zerfallende tabletten und verfahren zu ihrer herstellung.
ATE460401T1 (de) 1,2,4,5-tetrahydro-3h-benzazepinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE252542T1 (de) Benzolderivate, ein verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen,die diese enthalten
DE60318167D1 (de) Arzneiform und Verfahren zu ihrer Herstellung
DE60304599D1 (de) Pyridopyrimidinon-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
EG24479A (en) Modified release pharmaceutical formulation
DE602004026602D1 (de) Polymerteilchen und Verfahren zu ihrer Herstellung
DE602005003453D1 (de) Neue effektor-konjugate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
ATE372992T1 (de) Indanyl-piperazinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE337317T1 (de) Imidazopyrin-derivate, verfahren zu ihrer herstellung and sie enthaltende pharmazeutische zusamensetzungen
DE50307428D1 (de) Sitzeinlage und verfahren zu ihrer herstellung
DE60203178D1 (de) Pharmazeutische formulierung mit überdecktem geschmack und verfahren zu ihrer herstellung
ATE409463T1 (de) Oral dispergierbare pharmazeutische zusammensetzung und verfahren zu ihrer herstellung
ATE222586T1 (de) Benzolsulfonamidderivate und verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE358470T1 (de) Pharmazeutische zusammensetzung mit kontrollierter freisetzung und verfahren zu ihrer herstellung
DE60131637D1 (de) Granulare waschmittelkomponente und verfahren zu ihrer herstellung
ATE370927T1 (de) Pentensäurederivate, verfahren zu deren herstellung, pharmazeutische zusammensetzungen, die diese enthalten, und deren therapeutische anwendung
DE60300571D1 (de) [3,4-a:3,4-c]Carbazolderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE60322132D1 (de) Hydroxyphenyladamantane und Verfahren zu ihrer Herstellung
ATE248171T1 (de) Isoindoloindolon-derivate, verfahren zu ihrer herstellung und die enthaltende pharmazeutische zusammensetzungen
DE60200041D1 (de) Indenoindolon-Derivate, Verfahren zu ihrer Herstellung und die enthaltenden pharmazeutischen Zusammensetzungen
DE602004003719D1 (de) 9-aminopodophyllotoxinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die diese derivate enthalten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1480622

Country of ref document: EP