ATE415403T1 - Verfahren zur herstellung von alphaformkristallen von sapropterinhydrochlorid - Google Patents
Verfahren zur herstellung von alphaformkristallen von sapropterinhydrochloridInfo
- Publication number
- ATE415403T1 ATE415403T1 AT06732122T AT06732122T ATE415403T1 AT E415403 T1 ATE415403 T1 AT E415403T1 AT 06732122 T AT06732122 T AT 06732122T AT 06732122 T AT06732122 T AT 06732122T AT E415403 T1 ATE415403 T1 AT E415403T1
- Authority
- AT
- Austria
- Prior art keywords
- crystals
- hydrochloride
- sapropterine
- alphaform
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005116687 | 2005-04-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE415403T1 true ATE415403T1 (de) | 2008-12-15 |
Family
ID=36617398
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06732122T ATE415403T1 (de) | 2005-04-14 | 2006-04-13 | Verfahren zur herstellung von alphaformkristallen von sapropterinhydrochlorid |
Country Status (15)
Country | Link |
---|---|
US (1) | US8039617B2 (de) |
EP (1) | EP1869048B8 (de) |
JP (1) | JP4980230B2 (de) |
KR (1) | KR101258430B1 (de) |
CN (1) | CN101160310B (de) |
AT (1) | ATE415403T1 (de) |
AU (1) | AU2006237936B2 (de) |
BR (1) | BRPI0608863B1 (de) |
CA (1) | CA2604818C (de) |
DE (1) | DE602006003883D1 (de) |
DK (1) | DK1869048T3 (de) |
ES (1) | ES2317529T3 (de) |
PL (1) | PL1869048T3 (de) |
PT (1) | PT1869048E (de) |
WO (1) | WO2006112495A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101959891A (zh) | 2008-01-07 | 2011-01-26 | 生物马林药物股份有限公司 | 合成四氢生物蝶呤的方法 |
US9216178B2 (en) | 2011-11-02 | 2015-12-22 | Biomarin Pharmaceutical Inc. | Dry blend formulation of tetrahydrobiopterin |
CN108033963A (zh) * | 2017-12-29 | 2018-05-15 | 天津凯莱英制药有限公司 | 沙丙喋呤二盐酸盐晶型b及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60178887A (ja) | 1984-02-23 | 1985-09-12 | Kanegafuchi Chem Ind Co Ltd | 5,6,7,8−テトラヒドロ−l−ビオプテリンの製造法 |
JPS61172876A (ja) * | 1985-01-28 | 1986-08-04 | Shiratori Seiyaku Kk | (6r)−テトラヒドロ−l−バイオプテリンの製造法 |
CA1262347A (en) | 1985-01-28 | 1989-10-17 | Suntory Limited | Preparation process of (6r)-tetrahydro-l-biopterin |
JP2711828B2 (ja) | 1996-06-25 | 1998-02-10 | 白鳥製薬株式会社 | (6r)−テトラヒドローl−バイオプテリン塩酸塩の製造法 |
WO2005065018A2 (en) * | 2003-11-17 | 2005-07-21 | Merck Eprova Ag | Crystalline forms of (6r) -l-erythro-tetrahydrobiopterin dihydrochloride |
-
2006
- 2006-04-13 EP EP06732122A patent/EP1869048B8/de active Active
- 2006-04-13 CN CN2006800123950A patent/CN101160310B/zh active Active
- 2006-04-13 CA CA2604818A patent/CA2604818C/en active Active
- 2006-04-13 PT PT06732122T patent/PT1869048E/pt unknown
- 2006-04-13 WO PCT/JP2006/308264 patent/WO2006112495A1/en active Application Filing
- 2006-04-13 DK DK06732122T patent/DK1869048T3/da active
- 2006-04-13 AT AT06732122T patent/ATE415403T1/de active
- 2006-04-13 US US11/910,498 patent/US8039617B2/en active Active
- 2006-04-13 ES ES06732122T patent/ES2317529T3/es active Active
- 2006-04-13 DE DE602006003883T patent/DE602006003883D1/de active Active
- 2006-04-13 BR BRPI0608863-5A patent/BRPI0608863B1/pt active IP Right Grant
- 2006-04-13 KR KR1020077023138A patent/KR101258430B1/ko active IP Right Grant
- 2006-04-13 JP JP2007539415A patent/JP4980230B2/ja active Active
- 2006-04-13 PL PL06732122T patent/PL1869048T3/pl unknown
- 2006-04-13 AU AU2006237936A patent/AU2006237936B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN101160310A (zh) | 2008-04-09 |
CA2604818C (en) | 2012-12-04 |
JP4980230B2 (ja) | 2012-07-18 |
US20090270619A1 (en) | 2009-10-29 |
EP1869048A1 (de) | 2007-12-26 |
PT1869048E (pt) | 2009-03-05 |
BRPI0608863A2 (pt) | 2010-02-02 |
BRPI0608863B1 (pt) | 2022-09-27 |
ES2317529T3 (es) | 2009-04-16 |
DK1869048T3 (da) | 2009-03-09 |
CN101160310B (zh) | 2010-05-26 |
JP2008535770A (ja) | 2008-09-04 |
EP1869048B8 (de) | 2009-04-15 |
PL1869048T3 (pl) | 2009-05-29 |
EP1869048B1 (de) | 2008-11-26 |
CA2604818A1 (en) | 2006-10-26 |
KR101258430B1 (ko) | 2013-04-26 |
WO2006112495A1 (en) | 2006-10-26 |
AU2006237936A1 (en) | 2006-10-26 |
AU2006237936B2 (en) | 2011-06-16 |
KR20080000582A (ko) | 2008-01-02 |
US8039617B2 (en) | 2011-10-18 |
DE602006003883D1 (de) | 2009-01-08 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
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