ATE406463T1 - Methode zur krebsdiagnose mittels nachweis von dna und rna im kreislauf - Google Patents
Methode zur krebsdiagnose mittels nachweis von dna und rna im kreislaufInfo
- Publication number
- ATE406463T1 ATE406463T1 AT05007508T AT05007508T ATE406463T1 AT E406463 T1 ATE406463 T1 AT E406463T1 AT 05007508 T AT05007508 T AT 05007508T AT 05007508 T AT05007508 T AT 05007508T AT E406463 T1 ATE406463 T1 AT E406463T1
- Authority
- AT
- Austria
- Prior art keywords
- rna
- dna
- cancer
- circulation
- detection
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 201000011510 cancer Diseases 0.000 title abstract 5
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 210000002966 serum Anatomy 0.000 abstract 2
- 230000004544 DNA amplification Effects 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000003208 gene overexpression Methods 0.000 abstract 1
- 238000011002 quantification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05007508A EP1712639B1 (de) | 2005-04-06 | 2005-04-06 | Methode zur Krebsdiagnose mittels Nachweis von DNA und RNA im Kreislauf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406463T1 true ATE406463T1 (de) | 2008-09-15 |
Family
ID=34934801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05007508T ATE406463T1 (de) | 2005-04-06 | 2005-04-06 | Methode zur krebsdiagnose mittels nachweis von dna und rna im kreislauf |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7700286B2 (de) |
| EP (1) | EP1712639B1 (de) |
| AT (1) | ATE406463T1 (de) |
| DE (1) | DE602005009324D1 (de) |
| ES (1) | ES2313143T3 (de) |
| PL (1) | PL1712639T3 (de) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7425217B2 (en) * | 2000-11-16 | 2008-09-16 | Maier Nathan C | System and method for inhibiting cellular proliferation with tachykinins |
| ATE406463T1 (de) | 2005-04-06 | 2008-09-15 | Maurice Stroun | Methode zur krebsdiagnose mittels nachweis von dna und rna im kreislauf |
| US12180549B2 (en) | 2007-07-23 | 2024-12-31 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using genomic sequencing |
| PL2183693T5 (pl) | 2007-07-23 | 2019-04-30 | Univ Hong Kong Chinese | Diagnozowanie aneuploidii chromosomów u płodu przy użyciu sekwencjonowania genomowego |
| FR2928657B1 (fr) * | 2008-03-14 | 2013-12-20 | Chu Saint Etienne Chu Hopital Nord | Methode, procede, et kit de diagnostic, pronostic, suivi d'un cancer |
| US8583380B2 (en) | 2008-09-05 | 2013-11-12 | Aueon, Inc. | Methods for stratifying and annotating cancer drug treatment options |
| US9090948B2 (en) | 2008-09-30 | 2015-07-28 | Abbott Molecular Inc. | Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples |
| JP5410722B2 (ja) * | 2008-09-30 | 2014-02-05 | 三菱化学メディエンス株式会社 | 膵臓の組織傷害あるいは細胞増殖性疾患の検出方法 |
| US8404444B2 (en) * | 2009-02-25 | 2013-03-26 | Diacarta Llc | Method for predicting the level of damage to cells by measuring free circulating Alu nucleic acid |
| US9085798B2 (en) | 2009-04-30 | 2015-07-21 | Prognosys Biosciences, Inc. | Nucleic acid constructs and methods of use |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| EP2556171B1 (de) | 2010-04-05 | 2015-09-02 | Prognosys Biosciences, Inc. | Räumlich kodierte biologische assays |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| US9309556B2 (en) | 2010-09-24 | 2016-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Direct capture, amplification and sequencing of target DNA using immobilized primers |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| EP2646579B1 (de) | 2010-11-30 | 2017-06-14 | The Chinese University Of Hong Kong | Detektion von mit krebs assoziierten genetischen oder molekularen veränderungen |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| EP3246416B1 (de) | 2011-04-15 | 2024-06-05 | The Johns Hopkins University | Sicheres sortierungssystem |
| LT3363901T (lt) | 2012-02-17 | 2021-04-12 | Fred Hutchinson Cancer Research Center | Kompozicijos ir būdai, skirti tiksliam mutacijų nustatymui |
| US9892230B2 (en) | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
| EP4424826A3 (de) | 2012-09-04 | 2024-11-27 | Guardant Health, Inc. | Systeme und verfahren zum nachweis seltener mutationen und kopienzahlvariationen |
| US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| ES3019910T3 (en) | 2012-10-17 | 2025-05-21 | 10X Genomics Sweden Ab | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| EP2912468B1 (de) | 2012-10-29 | 2018-09-12 | The Johns Hopkins University | Papanicolaou-test für ovarial- und endometriumkarzinome |
| CN105473744B (zh) | 2013-06-25 | 2020-06-19 | 普罗格诺西斯生物科学公司 | 采用微流控装置的空间编码生物分析 |
| US10227655B2 (en) | 2013-10-29 | 2019-03-12 | Region Syddanmark | Method for analyzing body fluid samples |
| US11859246B2 (en) | 2013-12-11 | 2024-01-02 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| IL300974A (en) | 2013-12-11 | 2023-04-01 | Accuragen Holdings Ltd | Preparations and methods for the detection of rare sequence variants |
| US11286519B2 (en) | 2013-12-11 | 2022-03-29 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| EP3378952B1 (de) | 2013-12-28 | 2020-02-05 | Guardant Health, Inc. | Verfahren und systeme für den nachweis genetischer varianten |
| PT3543356T (pt) | 2014-07-18 | 2021-10-04 | Univ Hong Kong Chinese | Análise dos padrões de metilação de tecidos em mistura de adn |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| US10364467B2 (en) | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
| CN107532124B (zh) | 2015-03-27 | 2022-08-09 | 精密科学公司 | 检测食管疾病 |
| CN113186256B (zh) | 2015-04-10 | 2025-05-23 | 十程基因技术瑞典公司 | 生物样本的空间区别、多重核酸分析 |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| HK1259101A1 (zh) | 2015-10-09 | 2019-11-22 | Accuragen Holdings Limited | 用於富集扩增产物的方法及组合物 |
| WO2017075061A1 (en) | 2015-10-30 | 2017-05-04 | Exact Sciences Corporation | Multiplex amplification detection assay and isolation and detection of dna from plasma |
| WO2017096322A1 (en) | 2015-12-03 | 2017-06-08 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| WO2017106768A1 (en) | 2015-12-17 | 2017-06-22 | Guardant Health, Inc. | Methods to determine tumor gene copy number by analysis of cell-free dna |
| EP3458586B1 (de) | 2016-05-16 | 2022-12-28 | Accuragen Holdings Limited | Verfahren zur verbesserten sequenzierung durch strangidentifizierung |
| WO2018035170A1 (en) | 2016-08-15 | 2018-02-22 | Accuragen Holdings Limited | Compositions and methods for detecting rare sequence variants |
| US9850523B1 (en) | 2016-09-30 | 2017-12-26 | Guardant Health, Inc. | Methods for multi-resolution analysis of cell-free nucleic acids |
| ES2840003T3 (es) | 2016-09-30 | 2021-07-06 | Guardant Health Inc | Métodos para análisis multi-resolución de ácidos nucleicos libres de células |
| CA3039685A1 (en) | 2016-11-30 | 2018-06-07 | The Chinese University Of Hong Kong | Analysis of cell-free dna in urine and other samples |
| AU2018211956B2 (en) | 2017-01-27 | 2024-06-20 | Exact Sciences Corporation | Detection of colon neoplasia by analysis of methylated DNA |
| US10907211B1 (en) | 2017-02-16 | 2021-02-02 | Quantgene Inc. | Methods and compositions for detecting cancer biomarkers in bodily fluids |
| WO2018183942A1 (en) | 2017-03-31 | 2018-10-04 | Grail, Inc. | Improved library preparation and use thereof for sequencing-based error correction and/or variant identification |
| CA3072195A1 (en) | 2017-08-07 | 2019-04-04 | The Johns Hopkins University | Methods and materials for assessing and treating cancer |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| US11203782B2 (en) | 2018-03-29 | 2021-12-21 | Accuragen Holdings Limited | Compositions and methods comprising asymmetric barcoding |
| WO2019241290A1 (en) | 2018-06-12 | 2019-12-19 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| US12529094B2 (en) | 2018-12-10 | 2026-01-20 | 10X Genomics, Inc. | Imaging system hardware |
| CN113767177B (zh) | 2018-12-10 | 2025-01-14 | 10X基因组学有限公司 | 生成用于空间分析的捕获探针 |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| EP4567131A3 (de) | 2019-01-31 | 2025-09-03 | Guardant Health, Inc. | Zusammensetzungen und verfahren zur isolierung von zellfreier dna |
| AU2020279106B2 (en) | 2019-05-17 | 2025-12-18 | The Johns Hopkins University | Rapid aneuploidy detection |
| WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| EP4055185A1 (de) | 2019-11-08 | 2022-09-14 | 10X Genomics, Inc. | Räumlich markierte analytfänger für analyt-multiplexing |
| FI3891300T3 (fi) | 2019-12-23 | 2023-05-10 | 10X Genomics Inc | Menetelmät spatiaalista analyysiä varten rna-templatoitua ligaatiota käyttäen |
| MX2022010038A (es) | 2020-02-14 | 2022-09-05 | Univ Johns Hopkins | Metodos y materiales para la evaluacion de acidos nucleicos. |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| AU2021283184A1 (en) | 2020-06-02 | 2023-01-05 | 10X Genomics, Inc. | Spatial transcriptomics for antigen-receptors |
| WO2021247543A2 (en) | 2020-06-02 | 2021-12-09 | 10X Genomics, Inc. | Nucleic acid library methods |
| ES2981265T3 (es) | 2020-06-08 | 2024-10-08 | 10X Genomics Inc | Métodos para determinar un margen quirúrgico y métodos de uso del mismo |
| WO2022140028A1 (en) | 2020-12-21 | 2022-06-30 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| CN117241878A (zh) | 2021-03-05 | 2023-12-15 | 伊努梅里斯公司 | 用于生成微滴和执行数字分析的系统和方法 |
| EP4301870B1 (de) | 2021-03-18 | 2025-01-15 | 10X Genomics, Inc. | Multiplex-erfassung von gen- und proteinexpression aus einer biologischen probe |
| CN113238052B (zh) * | 2021-04-27 | 2023-07-25 | 中国人民解放军空军军医大学 | MG7-Ag、hTERT及TFF2表达分析在肠上皮化生风险分层及胃癌预警中的应用 |
| WO2022256503A1 (en) | 2021-06-03 | 2022-12-08 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
| EP4305195A2 (de) | 2021-12-01 | 2024-01-17 | 10X Genomics, Inc. | Verfahren, zusammensetzungen und systeme für verbesserten in-situ-nachweis von analyten und raumanalyse |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2115611T3 (es) | 1990-01-04 | 1998-07-01 | Univ Johns Hopkins | Gen suprimido en el cancer colorrectal humano. |
| EP0655090B1 (de) | 1992-04-27 | 2000-12-27 | The Trustees Of Dartmouth College | Detektion von gensequenzen in biologischen flüssigkeiten |
| CH686982A5 (fr) | 1993-12-16 | 1996-08-15 | Maurice Stroun | Méthode pour le diagnostic de cancers. |
| US5569753A (en) | 1994-12-20 | 1996-10-29 | Cold Spring Harbor Laboratory | Cancer detection probes |
| US5648245A (en) | 1995-05-09 | 1997-07-15 | Carnegie Institution Of Washington | Method for constructing an oligonucleotide concatamer library by rolling circle replication |
| EP0929694A4 (de) | 1996-03-15 | 2002-05-02 | Penn State Res Found | Nachweis von extrazellulärer tumor-assoziierter nukleinsäuren im blutplasma oder -serum mittels eines nukleinsäure-amplifizierungsverfahren |
| DE69739909D1 (de) | 1996-03-26 | 2010-07-29 | Michael S Kopreski | Methoden aus plasma oder serum extrahierte extrazelluraere rna zur diagnoseüberwachung oder evaluation von krebs verwenden |
| US6607898B1 (en) | 1996-03-26 | 2003-08-19 | Oncomedx, Inc. | Method for detection of hTR and hTERT telomerase-associated RNA in plasma or serum |
| US7785842B2 (en) | 1996-03-26 | 2010-08-31 | Oncomedx, Inc. | Comparative analysis of extracellular RNA species |
| US6590088B1 (en) * | 1996-07-19 | 2003-07-08 | Human Genome Sciences, Inc. | CD33-like protein |
| JP2002503480A (ja) | 1998-02-16 | 2002-02-05 | ユニバーシティ オブ メリーランド, ボルチモア | がんスクリーニングならびに疾病段階および予後の評価のための体液のテロメラーゼ・アッセイ |
| CA2366459A1 (en) | 1999-03-26 | 2000-10-05 | Affymetrix, Inc. | Universal arrays |
| CA2304260C (en) | 1999-04-20 | 2009-03-24 | Japan Bioindustry Association | Method for determining a concentration of target nucleic acid molecules, nucleic acid probes for the method and method for analyzing data obtained by the method |
| US6440706B1 (en) | 1999-08-02 | 2002-08-27 | Johns Hopkins University | Digital amplification |
| US6586177B1 (en) | 1999-09-08 | 2003-07-01 | Exact Sciences Corporation | Methods for disease detection |
| US6849403B1 (en) | 1999-09-08 | 2005-02-01 | Exact Sciences Corporation | Apparatus and method for drug screening |
| US6664046B1 (en) | 1999-12-16 | 2003-12-16 | Roche Molecular Systems, Inc. | Quantitation of hTERT mRNA expression |
| US20020072058A1 (en) | 2000-03-24 | 2002-06-13 | Voelker Leroy L. | Method for amplifying quinolone-resistance-determining-regions and identifying polymorphic variants thereof |
| EP1158055A1 (de) * | 2000-05-26 | 2001-11-28 | Xu Qi University of Teaxs Laboratoire de Leucémie Chen | Verfahren zur Diagnose von Krebs |
| US20050095592A1 (en) * | 2002-02-13 | 2005-05-05 | Jazaeri Amir A. | Identification of ovarian cancer tumor markers and therapeutic targets |
| AU2003261101A1 (en) * | 2002-06-28 | 2004-01-19 | Hong Kong University Of Science And Technology | Plasma or serum marker and process for detection of cancer |
| ITMI20022743A1 (it) * | 2002-12-23 | 2004-06-24 | Ist Naz Stud Cura Dei Tumori | Metodo per la determinazione del rischio di comparsa, della presenza o del decorso di malattie tumorali. |
| US20040259101A1 (en) * | 2003-06-20 | 2004-12-23 | Shuber Anthony P. | Methods for disease screening |
| EP1641809B2 (de) | 2003-07-05 | 2018-10-03 | The Johns Hopkins University | Verfahren und zusammensetzungen zum nachweis und zur auflistung genetischer variationen |
| US20100216153A1 (en) | 2004-02-27 | 2010-08-26 | Helicos Biosciences Corporation | Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities |
| US7937225B2 (en) | 2004-09-03 | 2011-05-03 | New York University | Systems, methods and software arrangements for detection of genome copy number variation |
| EP1647600A3 (de) | 2004-09-17 | 2006-06-28 | Affymetrix, Inc. (A US Entity) | Verfahren zur Kennzeichnung von biologischen Proben durch Hinzufügung von Nukleinsäre "bar-code" Markierungen |
| WO2006047787A2 (en) | 2004-10-27 | 2006-05-04 | Exact Sciences Corporation | Method for monitoring disease progression or recurrence |
| ATE406463T1 (de) | 2005-04-06 | 2008-09-15 | Maurice Stroun | Methode zur krebsdiagnose mittels nachweis von dna und rna im kreislauf |
| ES2426031T3 (es) | 2005-10-24 | 2013-10-18 | The Johns Hopkins University | Métodos mejorados para BEAMing |
| US7702468B2 (en) | 2006-05-03 | 2010-04-20 | Population Diagnostics, Inc. | Evaluating genetic disorders |
| EP2518162B1 (de) | 2006-11-15 | 2018-03-07 | Biospherex LLC | Mehrfach-Tags-Sequenzierung und ökogenomische Analyse |
| WO2008150432A1 (en) | 2007-06-01 | 2008-12-11 | 454 Life Sciences Corporation | System and meth0d for identification of individual samples from a multiplex mixture |
| PL2183693T5 (pl) | 2007-07-23 | 2019-04-30 | Univ Hong Kong Chinese | Diagnozowanie aneuploidii chromosomów u płodu przy użyciu sekwencjonowania genomowego |
| US12180549B2 (en) | 2007-07-23 | 2024-12-31 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using genomic sequencing |
| US20100041048A1 (en) | 2008-07-31 | 2010-02-18 | The Johns Hopkins University | Circulating Mutant DNA to Assess Tumor Dynamics |
| CA3116156C (en) | 2008-08-04 | 2023-08-08 | Natera, Inc. | Methods for allele calling and ploidy calling |
| US20100069250A1 (en) | 2008-08-16 | 2010-03-18 | The Board Of Trustees Of The Leland Stanford Junior University | Digital PCR Calibration for High Throughput Sequencing |
| US20100323348A1 (en) | 2009-01-31 | 2010-12-23 | The Regents Of The University Of Colorado, A Body Corporate | Methods and Compositions for Using Error-Detecting and/or Error-Correcting Barcodes in Nucleic Acid Amplification Process |
| ES2704701T3 (es) | 2010-01-19 | 2019-03-19 | Verinata Health Inc | Nuevo protocolo de preparación de bibliotecas de secuenciación |
| US20120100548A1 (en) | 2010-10-26 | 2012-04-26 | Verinata Health, Inc. | Method for determining copy number variations |
| US20110177512A1 (en) | 2010-01-19 | 2011-07-21 | Predictive Biosciences, Inc. | Method for assuring amplification of an abnormal nucleic acid in a sample |
| WO2012014877A1 (ja) | 2010-07-29 | 2012-02-02 | Toto株式会社 | 光触媒塗装体および光触媒コーティング液 |
| EP2426217A1 (de) | 2010-09-03 | 2012-03-07 | Centre National de la Recherche Scientifique (CNRS) | Analytische Verfahren für zellfreie Nucleinsäuren und Anwendungen |
| ES2690753T3 (es) | 2010-09-21 | 2018-11-22 | Agilent Technologies, Inc. | Aumento de la confianza en las identificaciones de alelos con el recuento molecular |
| EP3702475A1 (de) | 2010-10-22 | 2020-09-02 | Cold Spring Harbor Laboratory | Sortenreine zählung von nukleinsäuren zur gewinnung von informationen über genkopienzahlen |
| CA2834291A1 (en) | 2011-04-25 | 2012-11-01 | Biorad Laboratories, Inc. | Methods and compositions for nucleic acid analysis |
| EP2710172B1 (de) | 2011-05-20 | 2017-03-29 | Fluidigm Corporation | Nukleinsäure-kodierungsreaktionen |
| WO2013019075A2 (ko) | 2011-08-01 | 2013-02-07 | 연세대학교산학협력단 | 핵산분자의 제조방법 |
-
2005
- 2005-04-06 AT AT05007508T patent/ATE406463T1/de not_active IP Right Cessation
- 2005-04-06 DE DE602005009324T patent/DE602005009324D1/de not_active Expired - Lifetime
- 2005-04-06 PL PL05007508T patent/PL1712639T3/pl unknown
- 2005-04-06 EP EP05007508A patent/EP1712639B1/de not_active Expired - Lifetime
- 2005-04-06 ES ES05007508T patent/ES2313143T3/es not_active Expired - Lifetime
-
2006
- 2006-01-23 US US11/336,780 patent/US7700286B2/en not_active Ceased
-
2012
- 2012-04-13 US US13/447,104 patent/USRE44596E1/en active Active
-
2013
- 2013-09-27 US US14/039,168 patent/USRE49542E1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1712639A1 (de) | 2006-10-18 |
| PL1712639T3 (pl) | 2009-02-27 |
| US20060228727A1 (en) | 2006-10-12 |
| USRE49542E1 (en) | 2023-06-06 |
| ES2313143T3 (es) | 2009-03-01 |
| USRE44596E1 (en) | 2013-11-12 |
| DE602005009324D1 (de) | 2008-10-09 |
| US7700286B2 (en) | 2010-04-20 |
| EP1712639B1 (de) | 2008-08-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE406463T1 (de) | Methode zur krebsdiagnose mittels nachweis von dna und rna im kreislauf | |
| EA201170933A1 (ru) | Анализ нуклеиновых кислот, полученных из единичных клеток | |
| WO2006091776A3 (en) | Biomarkers for predicting prostate cancer progression | |
| WO2014140933A3 (en) | Method for the prognosis and treatment of cancer metastasis | |
| BRPI0518086A (pt) | métodos para tratamento de cáncer, métodos de avaliação de fosforilação ou ativação de her e método de identificação | |
| WO2007135568A3 (en) | A METHOD FOR PREDICTING RESPONSIVENESS TO TNFα BLOCKING AGENTS | |
| CY1111612T1 (el) | Μεθοδος για προβλεψη της αποκρισης σε μια θεραπευτικη αγωγη με εναν αναστολεαδιmερισmου του her | |
| NZ593229A (en) | Gene expression markers (gadd45b) for colorectal cancer prognosis | |
| EA200702203A1 (ru) | Способы и нуклеиновые кислоты для анализов клеточных пролиферативных нарушений | |
| DK2114990T5 (da) | Fremgangsmåde til forudsigelse af NSCLC-patienters respons på behandling med en EGFR-TK-inhibitor | |
| ATE547537T1 (de) | Verfahren zur bestimmung der dna-methylierung in blut- oder urinproben | |
| EA200971079A1 (ru) | ГЕНЕТИЧЕСКИЕ ВАРИАНТЫ В Chr5p12 И 10q26 В КАЧЕСТВЕ МАРКЕРОВ ДЛЯ ПРИМЕНЕНИЯ ПРИ ОЦЕНКЕ РИСКА, ДИАГНОСТИРОВАНИИ, ПРОГНОЗИРОВАНИИ И ЛЕЧЕНИИ РАКА ГРУДИ | |
| EP2569453A4 (de) | Nukleinsäure-isolationsverfahren | |
| EP3179393A3 (de) | Genexpressionsprofilalgorithmus und test zur bestimmung der prognose von prostatakrebs | |
| EP2321430B8 (de) | Verfahren zur bewertung des oralkarzinomrisikos bei menschen | |
| WO2005059108A3 (en) | Gene expression profiles and methods of use | |
| WO2005084109A3 (en) | Cancer specific gene mh15 | |
| WO2008073177A3 (en) | Expression profiles associated with irinotecan treatment | |
| WO2005032495A8 (en) | Gene expression profiles and methods of use | |
| WO2004078035A3 (en) | Expression profiles for breast cancer and methods of use | |
| WO2009097511A3 (en) | Two stage enrichment of cell-free fetal dna in maternal plasma | |
| ATE493517T1 (de) | Kontrollgene zur normalisierung von genexpressionsanalysedaten | |
| WO2009003706A3 (en) | Methods, kits, and compounds for determining responsiveness to treatment of a pathological disorder by epothilones | |
| MXPA05014220A (es) | Genes regulados en cancer ovarico como objetivos de pronostico y terapeuticos. | |
| WO2009061640A3 (en) | Hepatitis b virus (hbv) specific oligonucleotide sequences |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |