DK2630263T4 - Varital tælling af nucleinsyrer for at opnå information om antal genomiske kopier - Google Patents
Varital tælling af nucleinsyrer for at opnå information om antal genomiske kopier Download PDFInfo
- Publication number
- DK2630263T4 DK2630263T4 DK11835243.4T DK11835243T DK2630263T4 DK 2630263 T4 DK2630263 T4 DK 2630263T4 DK 11835243 T DK11835243 T DK 11835243T DK 2630263 T4 DK2630263 T4 DK 2630263T4
- Authority
- DK
- Denmark
- Prior art keywords
- varital
- information
- nucleic acid
- genomic copies
- acid counting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40606710P | 2010-10-22 | 2010-10-22 | |
| US201161510579P | 2011-07-22 | 2011-07-22 | |
| PCT/US2011/057350 WO2012054873A2 (en) | 2010-10-22 | 2011-10-21 | Varietal counting of nucleic acids for obtaining genomic copy number information |
| US13/278,333 US9404156B2 (en) | 2010-10-22 | 2011-10-21 | Varietal counting of nucleic acids for obtaining genomic copy number information |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK2630263T3 DK2630263T3 (da) | 2018-07-23 |
| DK2630263T4 true DK2630263T4 (da) | 2022-02-14 |
Family
ID=45975922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11835243.4T DK2630263T4 (da) | 2010-10-22 | 2011-10-21 | Varital tælling af nucleinsyrer for at opnå information om antal genomiske kopier |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9404156B2 (da) |
| EP (4) | EP2630263B2 (da) |
| AU (1) | AU2011316807C1 (da) |
| CA (4) | CA3080699A1 (da) |
| DK (1) | DK2630263T4 (da) |
| ES (1) | ES2688458T5 (da) |
| HU (1) | HUE039766T2 (da) |
| PL (1) | PL2630263T5 (da) |
| PT (1) | PT2630263T (da) |
| SI (1) | SI2630263T2 (da) |
| TR (1) | TR201810530T4 (da) |
| WO (1) | WO2012054873A2 (da) |
Families Citing this family (67)
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| PL1712639T3 (pl) | 2005-04-06 | 2009-02-27 | Maurice Stroun | Sposób diagnozowania nowotworu przez wykrywanie krążącego DNA i RNA |
| WO2010127186A1 (en) | 2009-04-30 | 2010-11-04 | Prognosys Biosciences, Inc. | Nucleic acid constructs and methods of use |
| US9677139B2 (en) | 2009-12-11 | 2017-06-13 | Cold Spring Harbor Laboratory | Genetic markers indicative of a cancer patient response to trastuzumab (herceptin) |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| CN102834526B (zh) | 2010-04-05 | 2015-12-02 | 普罗格诺西斯生物科学公司 | 空间编码的生物学测定 |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| EP2561078B1 (en) | 2010-04-23 | 2018-09-19 | Cold Spring Harbor Laboratory | NOVEL STRUCTURALLY DESIGNED shRNAs |
| PT2630263T (pt) | 2010-10-22 | 2018-07-31 | Cold Spring Harbor Laboratory | Contagem varietal de ácidos nucleicos para obtenção de informação sobre o número de cópias genómicas |
| WO2012129363A2 (en) | 2011-03-24 | 2012-09-27 | President And Fellows Of Harvard College | Single cell nucleic acid detection and analysis |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| EP3246416B1 (en) | 2011-04-15 | 2024-06-05 | The Johns Hopkins University | Safe sequencing system |
| EP3854873A1 (en) | 2012-02-17 | 2021-07-28 | Fred Hutchinson Cancer Research Center | Compositions and methods for accurately identifying mutations |
| US20150011396A1 (en) | 2012-07-09 | 2015-01-08 | Benjamin G. Schroeder | Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing |
| US10041127B2 (en) | 2012-09-04 | 2018-08-07 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
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| EP2986741B1 (en) | 2013-04-17 | 2019-07-24 | Agency For Science, Technology And Research | Method for generating extended sequence reads |
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| EP3068883B1 (en) * | 2013-11-13 | 2020-04-29 | Nugen Technologies, Inc. | Compositions and methods for identification of a duplicate sequencing read |
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| SG11201700891SA (en) | 2014-08-06 | 2017-03-30 | Nugen Technologies Inc | Digital measurements from targeted sequencing |
| AU2015330685B2 (en) * | 2014-10-10 | 2022-02-17 | Cold Spring Harbor Laboratory | Random nucleotide mutation for nucleotide template counting and assembly |
| US10233490B2 (en) | 2014-11-21 | 2019-03-19 | Metabiotech Corporation | Methods for assembling and reading nucleic acid sequences from mixed populations |
| WO2016123692A1 (en) * | 2015-02-04 | 2016-08-11 | The University Of British Columbia | Methods and devices for analyzing particles |
| AU2016220135B2 (en) | 2015-02-17 | 2021-07-29 | Dovetail Genomics Llc | Nucleic acid sequence assembly |
| US11807896B2 (en) | 2015-03-26 | 2023-11-07 | Dovetail Genomics, Llc | Physical linkage preservation in DNA storage |
| SG11201707515SA (en) | 2015-04-10 | 2017-10-30 | Spatial Transcriptomics Ab | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| US11302416B2 (en) | 2015-09-02 | 2022-04-12 | Guardant Health | Machine learning for somatic single nucleotide variant detection in cell-free tumor nucleic acid sequencing applications |
| CN108603190B (zh) | 2015-09-08 | 2023-05-23 | 美国冷泉港实验室 | 使用经破碎的核苷酸的高通量多重测序确定基因拷贝数 |
| CA3002740A1 (en) | 2015-10-19 | 2017-04-27 | Dovetail Genomics, Llc | Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection |
| CA3008651A1 (en) | 2015-12-17 | 2017-06-22 | Guardant Health, Inc. | Methods to determine tumor gene copy number by analysis of cell-free dna |
| SG11201807117WA (en) | 2016-02-23 | 2018-09-27 | Dovetail Genomics Llc | Generation of phased read-sets for genome assembly and haplotype phasing |
| EP3443066A4 (en) | 2016-04-14 | 2019-12-11 | Guardant Health, Inc. | EARLY DETECTION METHODS FOR CANCER |
| US11384382B2 (en) | 2016-04-14 | 2022-07-12 | Guardant Health, Inc. | Methods of attaching adapters to sample nucleic acids |
| CN109072288A (zh) * | 2016-05-02 | 2018-12-21 | 赛卢拉研究公司 | 精确的分子条形编码 |
| EP3455356B1 (en) | 2016-05-13 | 2021-08-04 | Dovetail Genomics LLC | Recovering long-range linkage information from preserved samples |
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| EP3461274B1 (en) | 2016-09-30 | 2020-11-04 | Guardant Health, Inc. | Methods for multi-resolution analysis of cell-free nucleic acids |
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| JP2022519045A (ja) | 2019-01-31 | 2022-03-18 | ガーダント ヘルス， インコーポレイテッド | 無細胞ｄｎａを単離するための組成物および方法 |
| WO2020227718A1 (en) | 2019-05-09 | 2020-11-12 | Catalog Technologies, Inc. | Data structures and operations for searching, computing, and indexing in dna-based data storage |
| EP4041920A1 (en) * | 2019-10-11 | 2022-08-17 | Catalog Technologies, Inc. | Nucleic acid security and authentication |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
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| BRPI0410636A (pt) | 2003-05-23 | 2006-07-18 | Cold Spring Harbor Lab | representação virtual de seqüências de nucleotìdeo |
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| US20060035258A1 (en) | 2004-08-06 | 2006-02-16 | Affymetrix, Inc. | Methods for identifying DNA copy number changes |
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| CA2811185C (en) * | 2010-09-21 | 2020-09-22 | Population Genetics Technologies Ltd. | Increasing confidence of allele calls with molecular counting |
| PT2630263T (pt) | 2010-10-22 | 2018-07-31 | Cold Spring Harbor Laboratory | Contagem varietal de ácidos nucleicos para obtenção de informação sobre o número de cópias genómicas |
| EP3246416B1 (en) | 2011-04-15 | 2024-06-05 | The Johns Hopkins University | Safe sequencing system |
-
2011
- 2011-10-21 PT PT118352434T patent/PT2630263T/pt unknown
- 2011-10-21 WO PCT/US2011/057350 patent/WO2012054873A2/en active Application Filing
- 2011-10-21 CA CA3080699A patent/CA3080699A1/en active Pending
- 2011-10-21 TR TR2018/10530T patent/TR201810530T4/tr unknown
- 2011-10-21 ES ES11835243T patent/ES2688458T5/es active Active
- 2011-10-21 CA CA2815076A patent/CA2815076C/en active Active
- 2011-10-21 SI SI201131525T patent/SI2630263T2/sl unknown
- 2011-10-21 EP EP11835243.4A patent/EP2630263B2/en active Active
- 2011-10-21 PL PL11835243T patent/PL2630263T5/pl unknown
- 2011-10-21 CA CA3210003A patent/CA3210003A1/en active Pending
- 2011-10-21 CA CA3080686A patent/CA3080686C/en active Active
- 2011-10-21 US US13/278,333 patent/US9404156B2/en active Active
- 2011-10-21 EP EP19201353.0A patent/EP3702475A1/en not_active Withdrawn
- 2011-10-21 EP EP23197909.7A patent/EP4328321A3/en active Pending
- 2011-10-21 DK DK11835243.4T patent/DK2630263T4/da active
- 2011-10-21 EP EP18169127.0A patent/EP3461914A1/en not_active Withdrawn
- 2011-10-21 AU AU2011316807A patent/AU2011316807C1/en active Active
- 2011-10-21 HU HUE11835243A patent/HUE039766T2/hu unknown
-
2016
- 2016-03-07 US US15/063,278 patent/US10947589B2/en active Active
-
2019
- 2019-02-07 US US16/269,818 patent/US20190153535A1/en active Pending
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