ATE406359T1 - Verfahren zum herstellen von isocoumarinen und zwischenprodukte hierfür - Google Patents
Verfahren zum herstellen von isocoumarinen und zwischenprodukte hierfürInfo
- Publication number
- ATE406359T1 ATE406359T1 AT00940911T AT00940911T ATE406359T1 AT E406359 T1 ATE406359 T1 AT E406359T1 AT 00940911 T AT00940911 T AT 00940911T AT 00940911 T AT00940911 T AT 00940911T AT E406359 T1 ATE406359 T1 AT E406359T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- group
- isocoumarines
- intermediate products
- isocoumarin
- Prior art date
Links
- 239000013067 intermediate product Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- SLAXQKBVDWOLFK-UHFFFAOYSA-N 2-(1-oxoisochromen-3-yl)acetic acid Chemical class C1=CC=C2C(=O)OC(CC(=O)O)=CC2=C1 SLAXQKBVDWOLFK-UHFFFAOYSA-N 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- ZHQLTKAVLJKSKR-UHFFFAOYSA-N homophthalic acid Chemical class OC(=O)CC1=CC=CC=C1C(O)=O ZHQLTKAVLJKSKR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/46—Preparation of carboxylic acid esters from ketenes or polyketenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20786399 | 1999-07-22 | ||
| JP21223999 | 1999-07-27 | ||
| JP33447199A JP2001097970A (ja) | 1999-07-27 | 1999-11-25 | イソクマリン誘導体の製造方法 |
| JP33655599 | 1999-11-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406359T1 true ATE406359T1 (de) | 2008-09-15 |
Family
ID=27476380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00940911T ATE406359T1 (de) | 1999-07-22 | 2000-06-30 | Verfahren zum herstellen von isocoumarinen und zwischenprodukte hierfür |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6426420B1 (de) |
| EP (1) | EP1200421B1 (de) |
| CN (1) | CN1214021C (de) |
| AT (1) | ATE406359T1 (de) |
| AU (1) | AU5571900A (de) |
| CA (1) | CA2379981C (de) |
| DE (1) | DE60040072D1 (de) |
| WO (1) | WO2001007429A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2002062781A1 (ja) | 2001-02-02 | 2004-06-10 | メルシャン株式会社 | イソクマリン誘導体の製造及びそのための合成中間体 |
| US6664401B2 (en) * | 2001-07-06 | 2003-12-16 | Ilex Products, Inc. | Process for preparing isocoumarins |
| JPWO2006051808A1 (ja) | 2004-11-09 | 2008-05-29 | 協和醗酵工業株式会社 | Ｈｓｐ９０ファミリー蛋白質阻害剤 |
| CN102382096A (zh) * | 2011-09-06 | 2012-03-21 | 清华大学 | 异香豆素及其衍生物的制备方法 |
| CN104803964B (zh) * | 2015-03-09 | 2017-05-24 | 华侨大学 | 多取代异香豆素衍生物及其制备方法 |
| CN111039900B (zh) * | 2019-02-28 | 2023-12-22 | 弈柯莱生物科技(集团)股份有限公司 | 1-吗啉-4-(2,4,5-三氟苯基)丁烷-1,3-二酮的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3839363A (en) * | 1972-04-25 | 1974-10-01 | Commercial Solvents Corp | Synthesis of zearalanone and related compounds and intermediates useful in the synthesis thereof |
| JPH08176138A (ja) * | 1994-12-19 | 1996-07-09 | Mercian Corp | イソクマリン誘導体 |
-
2000
- 2000-06-30 CN CNB008113505A patent/CN1214021C/zh not_active Expired - Fee Related
- 2000-06-30 WO PCT/JP2000/004371 patent/WO2001007429A1/en active IP Right Grant
- 2000-06-30 CA CA002379981A patent/CA2379981C/en not_active Expired - Fee Related
- 2000-06-30 DE DE60040072T patent/DE60040072D1/de not_active Expired - Fee Related
- 2000-06-30 AT AT00940911T patent/ATE406359T1/de not_active IP Right Cessation
- 2000-06-30 EP EP00940911A patent/EP1200421B1/de not_active Expired - Lifetime
- 2000-06-30 AU AU55719/00A patent/AU5571900A/en not_active Abandoned
- 2000-07-05 US US09/610,362 patent/US6426420B1/en not_active Expired - Fee Related
-
2002
- 2002-04-11 US US10/119,734 patent/US6548695B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6426420B1 (en) | 2002-07-30 |
| CN1387523A (zh) | 2002-12-25 |
| CA2379981A1 (en) | 2001-02-01 |
| DE60040072D1 (de) | 2008-10-09 |
| AU5571900A (en) | 2001-02-13 |
| US6548695B2 (en) | 2003-04-15 |
| CN1214021C (zh) | 2005-08-10 |
| US20020147350A1 (en) | 2002-10-10 |
| EP1200421B1 (de) | 2008-08-27 |
| CA2379981C (en) | 2008-10-28 |
| EP1200421A1 (de) | 2002-05-02 |
| WO2001007429A1 (en) | 2001-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |