ATE393771T1 - Neue antiphlogistische androstan derivate - 17- carboxy-lactone substituiert mit einer aryl- carboxylic estergruppe in der 17.alpha.-stelle - Google Patents

Neue antiphlogistische androstan derivate - 17- carboxy-lactone substituiert mit einer aryl- carboxylic estergruppe in der 17.alpha.-stelle

Info

Publication number
ATE393771T1
ATE393771T1 AT02785235T AT02785235T ATE393771T1 AT E393771 T1 ATE393771 T1 AT E393771T1 AT 02785235 T AT02785235 T AT 02785235T AT 02785235 T AT02785235 T AT 02785235T AT E393771 T1 ATE393771 T1 AT E393771T1
Authority
AT
Austria
Prior art keywords
sub
aryl
alpha
antiphlogistic
carboxy
Prior art date
Application number
AT02785235T
Other languages
German (de)
English (en)
Inventor
Keith Biggadike
Paul Jones
Jeremy John Payne
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE393771T1 publication Critical patent/ATE393771T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
AT02785235T 2001-10-20 2002-10-17 Neue antiphlogistische androstan derivate - 17- carboxy-lactone substituiert mit einer aryl- carboxylic estergruppe in der 17.alpha.-stelle ATE393771T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0125259.2A GB0125259D0 (en) 2001-10-20 2001-10-20 Novel compounds

Publications (1)

Publication Number Publication Date
ATE393771T1 true ATE393771T1 (de) 2008-05-15

Family

ID=9924247

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02785235T ATE393771T1 (de) 2001-10-20 2002-10-17 Neue antiphlogistische androstan derivate - 17- carboxy-lactone substituiert mit einer aryl- carboxylic estergruppe in der 17.alpha.-stelle

Country Status (9)

Country Link
US (1) US7405206B2 (enExample)
EP (1) EP1444248B1 (enExample)
JP (1) JP4495456B2 (enExample)
AT (1) ATE393771T1 (enExample)
AU (1) AU2002350561A1 (enExample)
DE (1) DE60226334T2 (enExample)
ES (1) ES2304457T3 (enExample)
GB (1) GB0125259D0 (enExample)
WO (1) WO2003035668A2 (enExample)

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CA2727196A1 (en) 2008-06-10 2009-12-17 Novartis Ag Organic compounds
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CN102834406A (zh) 2009-06-16 2012-12-19 默沙东公司 作为糖皮质激素受体激动剂的新的[3.2-c]杂芳基甾体、其组合物和用途
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CA2771432A1 (en) 2009-08-20 2011-02-24 Novartis Ag Heterocyclic oxime compounds
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WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
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JP6130391B2 (ja) 2011-11-23 2017-05-17 インテリカイン， エルエルシー Ｍｔｏｒ阻害剤を使用する強化された治療レジメン
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EP2968340A4 (en) 2013-03-15 2016-08-10 Intellikine Llc COMBINING KINASE INHIBITORS AND USES THEREOF
US10155001B2 (en) 2013-06-14 2018-12-18 Inserm (Institut National De La Sante Et De La Recherche Medicale) RAC1 inhibitors for inducing bronchodilation
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
BR112016024484A2 (pt) 2014-04-24 2017-08-15 Novartis Ag derivados de aminopiridina como inibidores de fosfatidilinositol 3-quinase
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Also Published As

Publication number Publication date
JP2005509642A (ja) 2005-04-14
US7405206B2 (en) 2008-07-29
WO2003035668A2 (en) 2003-05-01
JP4495456B2 (ja) 2010-07-07
GB0125259D0 (en) 2001-12-12
DE60226334T2 (de) 2009-06-04
AU2002350561A1 (en) 2003-05-06
DE60226334D1 (de) 2008-06-12
WO2003035668A3 (en) 2003-07-31
EP1444248A2 (en) 2004-08-11
US20050054622A1 (en) 2005-03-10
EP1444248B1 (en) 2008-04-30
ES2304457T3 (es) 2008-10-16

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