ATE393144T1 - Verfahren zur herstellung substituierter 3- hydroxypiperidine - Google Patents
Verfahren zur herstellung substituierter 3- hydroxypiperidineInfo
- Publication number
- ATE393144T1 ATE393144T1 AT99115243T AT99115243T ATE393144T1 AT E393144 T1 ATE393144 T1 AT E393144T1 AT 99115243 T AT99115243 T AT 99115243T AT 99115243 T AT99115243 T AT 99115243T AT E393144 T1 ATE393144 T1 AT E393144T1
- Authority
- AT
- Austria
- Prior art keywords
- aryl
- hydroxypiperidines
- cycloalkyl
- chem
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98114974 | 1998-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE393144T1 true ATE393144T1 (de) | 2008-05-15 |
Family
ID=8232435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99115243T ATE393144T1 (de) | 1998-08-10 | 1999-08-02 | Verfahren zur herstellung substituierter 3- hydroxypiperidine |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6274735B1 (de) |
| EP (1) | EP0979819B1 (de) |
| JP (1) | JP3366289B2 (de) |
| KR (1) | KR100371727B1 (de) |
| CN (1) | CN1161335C (de) |
| AT (1) | ATE393144T1 (de) |
| CA (1) | CA2279779C (de) |
| DE (1) | DE69938577T2 (de) |
| DK (1) | DK0979819T3 (de) |
| ES (1) | ES2306493T3 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6268499B1 (en) | 1998-08-10 | 2001-07-31 | Hoffman-La Roche Inc. | Process and intermediates for preparation of substituted piperidine-epoxides |
| NZ533158A (en) * | 2001-11-19 | 2006-09-29 | Elan Pharm Inc | 3,4-Disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines and piperazines |
| JP2006511621A (ja) | 2002-12-18 | 2006-04-06 | エフ エム シー コーポレーション | Ｎ―（置換アリールメチル）―４―（二置換メチル）ピペリジン及びピペラジン |
| US6916833B2 (en) * | 2003-03-13 | 2005-07-12 | Hoffmann-La Roche Inc. | Substituted piperidines |
| BRPI0620736A2 (pt) * | 2005-12-30 | 2011-12-20 | Novartis Ag | compostos orgánicos |
| US7638541B2 (en) | 2006-12-28 | 2009-12-29 | Metabolex Inc. | 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine |
| ES2541107T3 (es) | 2007-06-25 | 2015-07-16 | Novartis Ag | Derivados de N5-(2-etoxietil)-N3-(2-piridinil)-3,5-piperidindicarboxamida para su uso como inhibidores de renina |
| US8183381B2 (en) | 2007-07-19 | 2012-05-22 | Metabolex Inc. | N-linked heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders |
| DK2280704T3 (en) * | 2008-03-31 | 2015-06-29 | Cymabay Therapeutics Inc | Oxymethylenarylforbindelser and uses thereof |
| KR20110026481A (ko) * | 2008-06-20 | 2011-03-15 | 메타볼렉스, 인코포레이티드 | 아릴 ｇｐｒ１１９ 작동약 및 이의 용도 |
| US8410127B2 (en) | 2009-10-01 | 2013-04-02 | Metabolex, Inc. | Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts |
| ES2676209T3 (es) | 2010-06-23 | 2018-07-17 | Metabolex Inc. | Composiciones de 5-etil-2-{4-[4-(4-tetrazol-1-il-fenoximetil)-tiazol-2-il]-piperidin-1-il}-pirimidina |
| US10292983B2 (en) | 2016-08-03 | 2019-05-21 | Cymabay Therapeutics, Inc. | Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4132710A (en) * | 1976-12-20 | 1979-01-02 | Ayerst, Mckenna And Harrison, Ltd. | [2]Benzopyrano[3,4-c]pyridines and process therefor |
| TR199800409T1 (xx) | 1995-09-07 | 1998-05-21 | F.Hoffmann-La Roche Ag | Kalp ve b�brek yetersizli�inin tedavii�in yeni 4-(oksialkoksifenil)-3-oksi-piperidinler |
-
1999
- 1999-07-01 US US09/345,917 patent/US6274735B1/en not_active Expired - Fee Related
- 1999-08-02 DE DE69938577T patent/DE69938577T2/de not_active Expired - Lifetime
- 1999-08-02 AT AT99115243T patent/ATE393144T1/de not_active IP Right Cessation
- 1999-08-02 ES ES99115243T patent/ES2306493T3/es not_active Expired - Lifetime
- 1999-08-02 DK DK99115243T patent/DK0979819T3/da active
- 1999-08-02 EP EP99115243A patent/EP0979819B1/de not_active Expired - Lifetime
- 1999-08-06 CA CA002279779A patent/CA2279779C/en not_active Expired - Fee Related
- 1999-08-09 CN CNB99117531XA patent/CN1161335C/zh not_active Expired - Fee Related
- 1999-08-09 KR KR10-1999-0032561A patent/KR100371727B1/ko not_active IP Right Cessation
- 1999-08-09 JP JP22474499A patent/JP3366289B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3366289B2 (ja) | 2003-01-14 |
| KR100371727B1 (ko) | 2003-02-07 |
| DE69938577D1 (de) | 2008-06-05 |
| CN1161335C (zh) | 2004-08-11 |
| EP0979819A1 (de) | 2000-02-16 |
| EP0979819B1 (de) | 2008-04-23 |
| CN1245800A (zh) | 2000-03-01 |
| ES2306493T3 (es) | 2008-11-01 |
| CA2279779C (en) | 2005-03-15 |
| DE69938577T2 (de) | 2009-06-04 |
| KR20000017192A (ko) | 2000-03-25 |
| CA2279779A1 (en) | 2000-02-10 |
| JP2000063355A (ja) | 2000-02-29 |
| US6274735B1 (en) | 2001-08-14 |
| DK0979819T3 (da) | 2008-08-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE174589T1 (de) | Verfahren zur herstellung von piperidinderivaten | |
| ATE393144T1 (de) | Verfahren zur herstellung substituierter 3- hydroxypiperidine | |
| HUT63305A (en) | Fungicidal compositions comprising triazolopyrimidine derivatives and process for producing the triazolopyrimidine derivatives | |
| DE60014548D1 (de) | Verfahren zur Herstellung eines 5-Phthalancarbonitrils, Zwischenprodukt dafür und Verfahren zur Herstellung des Zwischenproduktes | |
| ATE442363T1 (de) | Verfahren zur herstellung von pyridinverbindungen | |
| ATE278694T1 (de) | Verfahren zur herstellung von substituierte piperidinepoxiden | |
| ATE531702T1 (de) | Verfahren zur herstellung von epoxytriazolderivat und zwischenprodukten dafür | |
| ATE444281T1 (de) | Titanverbindung und verfahren zur herstellung optisch aktiver cyanhydrine | |
| DE60309251D1 (de) | Verfahren zur Herstellung von Donepezil | |
| ATE157971T1 (de) | Verfahren zur herstellung von aminotriazin- derivaten | |
| ATE365152T1 (de) | Verfahren zur herstellung fluorierter benzoesäuren | |
| ATE189453T1 (de) | Verfahren zur herstellung von 2-cyanobiphenyl- verbindungen | |
| ATE553081T1 (de) | Verfahren zur herstellung einer bakteriziden pyridinverbindung, und bakterizide pyridinverbindung | |
| ATE155132T1 (de) | Verfahren zur herstellung von amino- thiadiazolylacetylhaliden | |
| DE69928610D1 (de) | Verfahren zur Herstellung von 2-Carbamoyl-Pyridinen | |
| ATE223377T1 (de) | Verfahren zur herstellung von difluoracetophenon- derivaten | |
| DE3878700D1 (de) | Verfahren zur herstellung von thiazolobenzimidazolen und zwischenprodukte. | |
| ATE228993T1 (de) | Verfahren zur herstellung von 1,1,1-trifluoro-2- aminoalkane | |
| ATE212613T1 (de) | Verfahren zur herstellung von 1,7-diaryl- oder 1, 7-diheteroarylheptan-4-olen und synthesezwischenprodukte | |
| DK0455304T3 (da) | Fremgangsmåde til fremstilling af cykliske ketoner | |
| DE69716370D1 (de) | Verfahren zur herstellung von beta-lactam verbindungen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0979819 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |