ATE384954T1 - Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe - Google Patents

Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe

Info

Publication number
ATE384954T1
ATE384954T1 AT01993160T AT01993160T ATE384954T1 AT E384954 T1 ATE384954 T1 AT E384954T1 AT 01993160 T AT01993160 T AT 01993160T AT 01993160 T AT01993160 T AT 01993160T AT E384954 T1 ATE384954 T1 AT E384954T1
Authority
AT
Austria
Prior art keywords
gene induction
biological sample
blocking agent
sample
collecting
Prior art date
Application number
AT01993160T
Other languages
English (en)
Inventor
Frank Augello
Helge Bastian
Uwe Oelmuller
Lynne Rainen
Matthew Walenciak
Ralf Wyrich
Original Assignee
Becton Dickinson Co
Qiagen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/707,745 external-priority patent/US6602718B1/en
Application filed by Becton Dickinson Co, Qiagen Gmbh filed Critical Becton Dickinson Co
Application granted granted Critical
Publication of ATE384954T1 publication Critical patent/ATE384954T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525—Stabilizing or preserving

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
AT01993160T 2000-11-08 2001-11-07 Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe ATE384954T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/707,745 US6602718B1 (en) 2000-11-08 2000-11-08 Method and device for collecting and stabilizing a biological sample
US09/984,658 US6617170B2 (en) 2000-11-08 2001-10-30 Method and device for collecting and stabilizing a biological sample

Publications (1)

Publication Number Publication Date
ATE384954T1 true ATE384954T1 (de) 2008-02-15

Family

ID=27107945

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01993160T ATE384954T1 (de) 2000-11-08 2001-11-07 Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe

Country Status (8)

Country Link
US (1) US6821789B2 (de)
EP (1) EP1356302B1 (de)
JP (1) JP5192631B2 (de)
CN (1) CN100386441C (de)
AT (1) ATE384954T1 (de)
CA (1) CA2428864C (de)
DK (1) DK1356302T3 (de)
WO (1) WO2002056030A2 (de)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391550B1 (en) 1996-09-19 2002-05-21 Affymetrix, Inc. Identification of molecular sequence signatures and methods involving the same
US7569342B2 (en) * 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
US20080064108A1 (en) * 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
DE10006662A1 (de) * 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
EP1413874A1 (de) 2002-10-16 2004-04-28 Streck Laboratories, Inc. Verfahren und Vorrichtung zum Sammeln und Konservieren von Zellen für die Analyse
US7534621B2 (en) * 2003-02-07 2009-05-19 Canon Kabuhsiki Kashia Method of producing probe medium and method of immobilizing probe using probe medium
US20040248106A1 (en) * 2003-06-06 2004-12-09 Leonard Leslie A. Clinical array assays that include a sample quality evaluation step and compositions for use in practicing the same
US20050112635A1 (en) * 2003-09-22 2005-05-26 Becton, Dickinson And Company Quantification of analytes using internal standards
WO2005113147A2 (en) 2004-04-08 2005-12-01 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20080176209A1 (en) * 2004-04-08 2008-07-24 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20080146790A1 (en) * 2004-08-18 2008-06-19 Daniel Grolz Additive, Method, and Article For Dna Collection, Stabilization, and Purification
US7803523B2 (en) * 2004-08-27 2010-09-28 University Health Network Whole blood preparation for cytometric analysis of cell signaling pathways
EP2436409A1 (de) * 2004-09-28 2012-04-04 Mallinckrodt LLC Behälter mit eingeschränktem Qualitätswahrungsmittel
US20060094023A1 (en) * 2004-11-02 2006-05-04 Industrial Technology Research Institute Method for isolating nucleic acid by using amino surfactants
TWI294460B (en) * 2004-12-23 2008-03-11 Ind Tech Res Inst Method for stabilizing nucleic acids
US7608457B2 (en) * 2005-03-10 2009-10-27 Streck, Inc. Blood collection and testing improvements
US7419832B2 (en) * 2005-03-10 2008-09-02 Streck, Inc. Blood collection tube with surfactant
DE102005013261A1 (de) * 2005-03-22 2006-09-28 Adnagen Ag Reagenz und Verfahren zur Verhinderung der zeitabhängigen Expression in biologischen Zellen
DE102005015005A1 (de) 2005-04-01 2006-10-05 Qiagen Gmbh Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe
US20080280290A1 (en) * 2005-08-19 2008-11-13 Dawson Elliott P Method and Device for the Collection and Isolation of Nucleic Acid
FR2895993A1 (fr) * 2006-01-10 2007-07-13 Immunid Sarl Composition pour la stabilisation d'echantillons biologiques et procede de stabilisation
US20070190526A1 (en) * 2006-02-16 2007-08-16 Nexgen Diagnostics Llc Methods of extracting nucleic acids
US7748283B2 (en) * 2007-02-16 2010-07-06 Whatman, Inc. Controlled transfer biological sample collection devices and methods of using such devices
EP2126581B1 (de) 2007-03-20 2014-07-09 Becton Dickinson and Company Assays unter verwendung von wirkstoffen für oberflächenverstärkte raman-spektroskopie
CN101896276A (zh) * 2007-11-28 2010-11-24 智能管公司 用于生物标本的收集、刺激、稳定化和分析的装置、系统和方法
CA2946631C (en) 2008-03-05 2019-01-08 Becton, Dickinson And Company Capillary action collection device and container assembly
PL2262690T3 (pl) 2008-03-05 2021-11-08 Becton, Dickinson And Company Współformowany przebijalny korek i sposób jego wykonania
JP5674664B2 (ja) 2008-09-04 2015-02-25 ベックマン コールター， インコーポレイテッド パンキナーゼ活性化およびシグナリング経路の評価
US20100093551A1 (en) * 2008-10-09 2010-04-15 Decision Biomarkers, Inc. Liquid Transfer and Filter System
JP2012505639A (ja) * 2008-10-17 2012-03-08 ユニヴァルシテ リブレ デ ブリュッセル 生体試料を作用因子でパルスし、そのようにパルスした試料を安定化させる装置、キット及び方法
DE202010018561U1 (de) 2009-01-21 2017-08-28 Streck Inc. Blutsammelröhrchen
US11634747B2 (en) * 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
ES2649572T3 (es) 2009-02-18 2018-01-12 Streck Inc. Conservación de ácidos nucleicos fuera de las células
CA2780536C (en) 2009-11-09 2018-01-02 Streck, Inc. Stabilization of rna in and extracting from intact cells within a blood sample
US10105706B2 (en) 2010-01-19 2018-10-23 Becton, Dickinson And Company Container assembly and system for detection thereof
US20110195396A1 (en) * 2010-02-10 2011-08-11 Selinfreund Richard H Chewable compositions for the stabilization of diagnostic biomarkers
CN101787345B (zh) * 2010-03-10 2013-04-17 西安交通大学 一种用于细胞检查的体液样本收集、分离装置和方法
EP2388312A1 (de) * 2010-05-17 2011-11-23 Curetis AG Universell anwendbarer Lysepuffer und Verarbeitungsverfahren zur Lyse von Körperproben
US20130137586A1 (en) 2010-06-02 2013-05-30 Qiagen Gmbh Stabilization of nucleic acids in cell material-containing biological samples
ES2761654T3 (es) 2010-07-20 2020-05-20 Becton Dickinson Co Procedimiento para vincular resultados de pruebas diagnósticas rápidas de punto de atención con procedimientos basados en laboratorio
EP2598661B1 (de) 2010-07-26 2017-09-27 Biomatrica, INC. Zusammensetzungen zur stabilisierung von dna, rna und proteinen in speichel- und anderen biologischen proben während des transports und der lagerung bei umgebungstemperaturen
WO2012018638A2 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US8460620B2 (en) 2010-12-03 2013-06-11 Becton, Dickinson And Company Specimen collection container assembly
EP2704740B1 (de) 2011-05-04 2016-10-05 Streck, Inc. Inaktiviertes schweinegrippe-virus und verfahren zu seiner herstellung
CN102250876B (zh) * 2011-05-18 2014-08-13 李学敬 从生物材料中分离纯化rna的方法
CA2779850C (en) 2011-06-17 2016-08-09 Norgen Biotek Corporation Methods, reagents and kits for preservation of nucleic acids in biological samples
AU2012273121B2 (en) 2011-06-19 2016-08-25 Abogen, Inc. Devices, solutions and methods for sample collection
DE102011080853B4 (de) 2011-08-11 2014-03-27 Axagarius Gmbh & Co. Kg Verfahren zur Isolierung von RNA aus Volblutproben
EP3789500A1 (de) * 2011-08-12 2021-03-10 QIAGEN GmbH Verfahren zur isolierung von nukleinsäuren
EP2756079A1 (de) * 2011-09-13 2014-07-23 Qiagen GmbH Verfahren zur isolierung von nukleinsäuren aus einer tierärztlichen vollblutprobe
BR112014009294B1 (pt) 2011-10-20 2021-03-02 Becton, Dickinson And Company conjunto de recipiente
DE102012025557A1 (de) 2012-04-11 2013-10-17 Sarstedt Ag & Co. Vorrichtung zur Ent- und/oder Aufnahme von Körperflüssigkeiten, insbesondere Blut
IN2014DN09302A (de) 2012-04-13 2015-07-10 Becton Dickinson Co
US9427707B2 (en) 2012-08-10 2016-08-30 Jean I. Montagu Filtering blood
WO2014029791A1 (en) * 2012-08-21 2014-02-27 Qiagen Gmbh Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
EP2934572A4 (de) 2012-12-20 2016-11-23 Biomatrica Inc Formulierungen und verfahren zur stabilisierung von pcr-reagenzien
GB201303666D0 (en) 2013-03-01 2013-04-17 Goldsborough Andrew S Sample fixation and stabilisation
CA2917912C (en) 2013-07-24 2019-09-17 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
CN103789202B (zh) * 2014-01-26 2017-10-24 付士明 常温保存核酸的采集容器
WO2015160595A1 (en) * 2014-04-14 2015-10-22 Abbott Molecular, Inc. Medium used for blood sample collection and transport
JP6661554B2 (ja) 2014-06-10 2020-03-11 バイオマトリカ，インク． 周囲温度における血小板の安定化
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
CN105158455B (zh) * 2015-09-17 2018-10-16 深圳市钠科生物有限公司 一种提高样品检测精度和准确性的生物样品采集方法、装置、系统、生物样品稳定试剂及应用
JP2017099376A (ja) * 2015-11-19 2017-06-08 株式会社日吉 環境水試料の前処理方法、環境水試料の前処理剤、並びに、生物相又は生物の量の推定方法
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
JP6827048B2 (ja) 2015-12-08 2021-02-10 バイオマトリカ，インク． 赤血球沈降速度の低下
PL3205722T3 (pl) 2016-02-11 2019-05-31 Sarstedt Ag & Co Kg Urządzenie oraz sposób izolacji kwasów nukleinowych z krwi pełnej
SG11201808573YA (en) * 2016-03-31 2018-10-30 Berkeley Lights Inc Nucleic acid stabilization reagent, kits, and methods of use thereof
CA3025569A1 (en) 2016-05-27 2017-11-30 Norgen Biotek Corp. Preservation of cell-free nucleic acids in biological samples
CN109477098A (zh) * 2016-05-31 2019-03-15 Dna真诺泰克有限公司 用于从水溶液去除去垢剂的组合物、系统和方法
EP3491381B1 (de) 2016-07-29 2025-09-24 Streck LLC Suspensionszusammensetzung zur kontrolle einer hämatologischen analyse
CN108333346B (zh) * 2017-01-19 2021-07-06 深圳市新产业生物医学工程股份有限公司 dsDNA免疫磁性微球体系、其制备方法和应用以及保存液
JP7216652B2 (ja) * 2017-01-30 2023-02-01 セイフガード バイオシステムズ ホールディングズ リミテッド ビーズ破砕用チューブ並びに微生物からデオキシリボ核酸及び／又はリボ核酸を抽出する方法
ES2909392T3 (es) 2017-08-02 2022-05-06 Sarstedt Ag & Co Kg Procedimiento y composición para la estabilización de ácidos nucleicos libres de células y células
HUE068517T2 (hu) 2017-10-19 2024-12-28 Streck Llc A hemolízis és a véralvadás szabályozására, valamint az extracelluláris vezikulák stabilizálására szolgáló készítmények
US12031891B2 (en) 2017-12-29 2024-07-09 Hoffman-La Roche, Inc. Tissue sample preparation system
US20210235688A1 (en) * 2018-04-19 2021-08-05 Board Of Regents, The University Of Texas System Methods for measuring and stabilizing stat3 inhibitors
CN109090104A (zh) * 2018-09-27 2018-12-28 广州新诚生物科技有限公司 保存液及其制备方法和应用
CN109486904A (zh) * 2018-12-29 2019-03-19 广州阳普医疗科技股份有限公司 一种全血rna保存液及其应用
JP2023508411A (ja) * 2019-12-23 2023-03-02 バイオプセンス オサケユキチュア 血液試料からセルフリー核酸を抽出するための方法、自動化システムおよびカートリッジ
US20230358759A1 (en) * 2022-05-04 2023-11-09 Creative Medical Technologies, Inc. Cytokine based assessment of recipient ability to respond to stem cell therapy for cartilage regeneration
GB2623570B (en) * 2022-10-21 2025-07-23 Wobble Genomics Ltd Method and products for biomarker identification

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3847738A (en) * 1971-11-01 1974-11-12 American Hospital Supply Corp Blood collection and preservation unit
JPS6360931A (ja) * 1986-08-29 1988-03-17 Noboru Sato 血液または血液製剤保存液およびこれを用いた血液または血液製剤の保存方法
US5010183A (en) * 1989-07-07 1991-04-23 Macfarlane Donald E Process for purifying DNA and RNA using cationic detergents
DE4034036C2 (de) * 1990-10-26 1994-03-03 Diagen Inst Molekularbio Vorrichtung und Verfahren zur Isolierung von Nukleinsäuren aus Zellsuspensionen
US5459253A (en) * 1991-07-19 1995-10-17 Pharmacia P-L Biochemicals Inc. M-RNA purification
AU6230594A (en) * 1993-02-01 1994-08-29 University Of Iowa Research Foundation, The Quartenary amine surfactants and methods of using same in isolation of rna
US5300635A (en) * 1993-02-01 1994-04-05 University Of Iowa Research Foundation Quaternary amine surfactants and methods of using same in isolation of nucleic acids
US5906744A (en) * 1997-04-30 1999-05-25 Becton Dickinson And Company Tube for preparing a plasma specimen for diagnostic assays and method of making thereof
US5860937A (en) * 1997-04-30 1999-01-19 Becton, Dickinson & Company Evacuated sample collection tube with aqueous additive
US5932422A (en) * 1997-11-14 1999-08-03 Millennium Pharmaceuticals, Inc. Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase
DE19836559A1 (de) * 1998-08-12 2000-03-23 Antigen Gmbh Gefäß zur Entnahme von Blut
DE59912463D1 (de) * 1999-03-04 2005-09-29 Retsch Gmbh & Co Kg Verfahren und Vorrichtung zum Aufschluss von biologischem Material
US6916608B2 (en) * 1999-09-10 2005-07-12 Becton, Dickinson And Company Composition for providing long term stability to cells for diagnostic testing
DE10031236A1 (de) * 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
US6602718B1 (en) * 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample

Also Published As

Publication number Publication date
DK1356302T3 (da) 2008-06-02
EP1356302B1 (de) 2008-01-23
CA2428864C (en) 2011-04-12
JP5192631B2 (ja) 2013-05-08
JP2004534731A (ja) 2004-11-18
CA2428864A1 (en) 2002-07-18
CN1503910A (zh) 2004-06-09
US20040048384A1 (en) 2004-03-11
US6821789B2 (en) 2004-11-23
WO2002056030A2 (en) 2002-07-18
EP1356302A2 (de) 2003-10-29
WO2002056030A3 (en) 2003-08-28
CN100386441C (zh) 2008-05-07

Similar Documents

Publication Publication Date Title
ATE384954T1 (de) Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe
DE59800705D1 (de) Vorrichtung zum automatischen durchführen von chemischen bzw. biologischen verfahren
ATE534025T1 (de) Automatisches verfahren zur vorbereitung einer blutprobenanalyse und automatische vorrichtung dafür
DE602004027739D1 (de) Vorrichtung und verfahren zum sammeln von biologischen fluidproben und zur behandlung von ausgewählten komponenten
DE60132628D1 (de) Verfahren und vorrichtung zum sammeln und zum stabilisieren einer biologischen probe
ATE162222T1 (de) Verfahren zur extraktion, amplifikation und zum nachweis von nukleinsäuren aus vollblut
ATE281512T1 (de) Vorrichtung und verfahren zum testen einer biologischen flüssigkeit
DE602004015018D1 (de) Verfahren und Vorrichtung zur Behandlung biologischer und chemischer Proben
ATE340871T1 (de) Verfahren zur nicht-invasiven diagnose von transplantationen und transfusionen
ATE191513T1 (de) Verfahren zur amplifikation von nukleinsäuren
ATE266723T1 (de) Lösung die chaotropische mittel enthält und verwendung dieser lösung in verfahren zur isolierung von dna, rna und proteinen
WO2002072870A2 (en) Dry solid medium for storage and analysis of genetic material
ATE373729T1 (de) Verfahren zur selektiven detektion einer zielnukleinsäure
DE60233848D1 (de) Vorrichtung und Verfahren zur Handhabung von Behälter für biologischen Proben
ATE341646T1 (de) Verfahren zum nachweis und zur identifizierung von vogelmaterialen , und oligonukleotiden zur ausführung davon
DE60014399D1 (de) Schnelle und wirksame dns-immobilisierung aus einer probe ohne die verwendung von zelllysereagenzien
ATE317847T1 (de) Verfahren und vorrichtung zur nukleinsäurereinigung
DE60228194D1 (de) Verfahren und vorrichtung zum schnellen aufheizen von nmr-proben
DE60217351D1 (de) Verfahren zur identifizierung von proben eines säugetiers als auch ein kit zur durchführung des verfahrens
DE60334604D1 (de)
ATE287642T1 (de) Vorrichtung und verfahren zur entnahme von milchprodukten
DE69519122D1 (de) Nachweis von Nukleinsäure-Amplifikation mittels Fluoreszenz-Polarisation
DE50113601D1 (de) Verfahren und vorrichtung zum analysieren von chemischen oder biologischen proben
WO2006012302A3 (en) Methods for rna fluorescence in situ hybridization
DE10083109T1 (de) Verfahren zu einer Schnelldiagnostik des physiologischen Zustandes eines biologischen Objektes und Vorrichtung zu seiner Durchführung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1356302

Country of ref document: EP