ATE380873T1 - Prenylcystein carboxyl methyl-transferase, dns, welche für selbige kodiert, und ein verfahren zur suche nach hemmstoffen - Google Patents

Prenylcystein carboxyl methyl-transferase, dns, welche für selbige kodiert, und ein verfahren zur suche nach hemmstoffen

Info

Publication number
ATE380873T1
ATE380873T1 AT98931260T AT98931260T ATE380873T1 AT E380873 T1 ATE380873 T1 AT E380873T1 AT 98931260 T AT98931260 T AT 98931260T AT 98931260 T AT98931260 T AT 98931260T AT E380873 T1 ATE380873 T1 AT E380873T1
Authority
AT
Austria
Prior art keywords
inhibitors
prenylcystone
searching
same
dna coding
Prior art date
Application number
AT98931260T
Other languages
English (en)
Inventor
Mark Philips
Original Assignee
Univ New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York filed Critical Univ New York
Application granted granted Critical
Publication of ATE380873T1 publication Critical patent/ATE380873T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT98931260T 1997-06-11 1998-06-11 Prenylcystein carboxyl methyl-transferase, dns, welche für selbige kodiert, und ein verfahren zur suche nach hemmstoffen ATE380873T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4930497P 1997-06-11 1997-06-11

Publications (1)

Publication Number Publication Date
ATE380873T1 true ATE380873T1 (de) 2007-12-15

Family

ID=21959118

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98931260T ATE380873T1 (de) 1997-06-11 1998-06-11 Prenylcystein carboxyl methyl-transferase, dns, welche für selbige kodiert, und ein verfahren zur suche nach hemmstoffen

Country Status (9)

Country Link
US (3) US6184016B1 (de)
EP (1) EP1009833B1 (de)
JP (1) JP2002504827A (de)
AT (1) ATE380873T1 (de)
AU (1) AU8142598A (de)
CA (1) CA2293270A1 (de)
DE (1) DE69838843D1 (de)
IL (1) IL133129A0 (de)
WO (1) WO1998056924A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030181355A1 (en) * 1992-05-29 2003-09-25 Glenn Jeffrey S. Method for inhibition of viral infection
US5503973A (en) * 1992-05-29 1996-04-02 The Regents Of The University Of California Method for inhibition of viral morphogenesis
WO1997038697A1 (en) * 1996-04-15 1997-10-23 The Trustees Of The University Of Pennsylvania Sensitization of cells to radiation and chemotherapy
FR2773261B1 (fr) * 1997-12-30 2000-01-28 Commissariat Energie Atomique Procede pour le transfert d'un film mince comportant une etape de creation d'inclusions
CN1298449A (zh) * 1998-04-24 2001-06-06 昂尼克斯药物公司 与法尼基一定向的半胱氨酸羧甲基转移酶有关的新核酸和多肽
US7384759B2 (en) * 2000-12-11 2008-06-10 The Salk Institute For Biological Studies Methods and compositions for determinig enzymatic activity and specificity of chalcone O-methyltransferases
US20030228688A1 (en) * 2002-05-31 2003-12-11 Isis Pharmaceuticals Inc. Antisense modulation of isoprenylcysteine carboxyl methyltransferase expression
EP2400030B1 (de) 2004-05-18 2016-01-20 The Board of Trustees of the Leland Stanford Junior University Detektion von Proteintranslokation durch Beta-Galactosidase-Reporter-Fragmentkomplementierung
WO2014041349A1 (en) 2012-09-12 2014-03-20 Cancer Therapeutics Crc Pty Ltd Tetrahydropyran-4-ylethylamino- or tetrahydropyranyl-4-ethyloxy-pyrimidines or -pyridazines as isoprenylcysteincarboxymethyl transferase inhibitors
AU2018219226A1 (en) 2017-02-07 2019-08-15 Seattle Children's Hospital (dba Seattle Children's Research Institute) Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
WO2018160622A1 (en) 2017-02-28 2018-09-07 Endocyte, Inc. Compositions and methods for car t cell therapy
CN112055595A (zh) 2018-01-22 2020-12-08 恩多塞特公司 Car t细胞的使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043268A (en) 1990-05-04 1991-08-27 The Trustees Of Princeton University Substrates and inhibitors for prenyl cysteine methyltransferase enzymes
US5202456A (en) 1991-04-15 1993-04-13 The President And Fellows Of Harvard College Compounds for inhibition of protein methylation
WO1994023025A1 (en) 1993-03-31 1994-10-13 Cadus Pharmaceuticals, Inc. Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
AU733007B2 (en) 1996-09-24 2001-05-03 Cadus Pharmaceutical Corporation Methods and compositions for identifying receptor effectors
US5876055A (en) 1998-03-04 1999-03-02 Fontaine; John P. K. Automatic tolerance reducing greaseless fifth wheel using a wedge and jaw locking system that eliminates squirting
CN1298449A (zh) 1998-04-24 2001-06-06 昂尼克斯药物公司 与法尼基一定向的半胱氨酸羧甲基转移酶有关的新核酸和多肽

Also Published As

Publication number Publication date
EP1009833A1 (de) 2000-06-21
JP2002504827A (ja) 2002-02-12
IL133129A0 (en) 2001-03-19
US6184016B1 (en) 2001-02-06
CA2293270A1 (en) 1998-12-17
US6232108B1 (en) 2001-05-15
EP1009833B1 (de) 2007-12-12
US6432403B1 (en) 2002-08-13
WO1998056924A1 (en) 1998-12-17
AU8142598A (en) 1998-12-30
DE69838843D1 (de) 2008-01-24

Similar Documents

Publication Publication Date Title
DK0741694T3 (da) Phenyleddikesyrederivater, fremgangsmåder og mellemprodukter til deres fremstilling og midler indeholdende disse
ATE380873T1 (de) Prenylcystein carboxyl methyl-transferase, dns, welche für selbige kodiert, und ein verfahren zur suche nach hemmstoffen
DE69933216D1 (de) Erythropoietin-analog-menschliches serum-albumin fusionsprotein
EE03424B1 (et) Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod
DE69434520D1 (de) Biotinylierung von proteinen
AU3462899A (en) Sequence and method for genetic engineering of proteins with cell membrane translocating activity
DK325789D0 (da) Fremgangsmaade til forbedring af lagerstabiliteten af amidperoxysyrer og detergentsammensaetning omfattende disse
BR9407583A (pt) Processos para produzir uma proteina bcl-2 mutante para identificar agentes modulantes de bcl-2 candidatos um bcl-2 mutante e proteinas bcl-2 mutantes e para inibir a atividade repressora de morte de células de bcl-2 e polipeptideo bcl-2 mutante
KR890007750A (ko) 인간 조직 인자 억제제의 dna 클론
NO972716D0 (no) Modulator av funksjonen til FAS/APO1 reseptorer
PT1200561E (pt) Clone celular recombinante estavel, sua producao e utilizacao
FI822224A0 (fi) Stabiliseringsfoerfarande
IT8621502A0 (it) Procedimento di applicazione per la determinazione dei punti di intorbidamento e di fluidificazione
ATE113075T1 (de) Plasmide und wirtszellen zur expression von ina protein (ice nucleating protein).
ES2168282T3 (es) D-hidantoinasa recombinante, procedimiento para su preparacion y utilizacion.
SE8502540D0 (sv) Stable dentifrice containing dextranase
WO2000018909A3 (en) NUCLEIC ACIDS AND PROTEINS FROM $i(CENARCHAEUM SYMBIOSUM)
DK0939769T3 (da) Vertebrat-Smoothened-proteiner
ATE245424T1 (de) Verwendung von hyaluronsäure zur zellmobilisierung
PE42695A1 (es) Procedimiento para producir proteina c
BR9106555A (pt) Proteina,celula hospedeira e processos para a preparacao de uma proteina e de acido nucleico
DE3484912D1 (de) Peptidderivate und deren verwendung als substrate zur quantitativen bestimmung von enzymen.
DE3576966D1 (de) Zaehfluessiges cellulosehaltiges gemisch (paste) und deren verwendung zur herstellung von waessrigen ueberzugsdispersionen.
DE3667802D1 (de) Verfahren zur elektrochemischen oxydation von alkylpyridinen.
HUP0200285A2 (hu) Glükóz-dehidrogenáz fúziós fehérjék és alkalmazásuk expressziós rendszerekben

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties