IL133129A0 - Prenylcysteine carboxyl methyltransferase dna encoding same and a method of screening for inhibistors thereof - Google Patents
Prenylcysteine carboxyl methyltransferase dna encoding same and a method of screening for inhibistors thereofInfo
- Publication number
- IL133129A0 IL133129A0 IL13312998A IL13312998A IL133129A0 IL 133129 A0 IL133129 A0 IL 133129A0 IL 13312998 A IL13312998 A IL 13312998A IL 13312998 A IL13312998 A IL 13312998A IL 133129 A0 IL133129 A0 IL 133129A0
- Authority
- IL
- Israel
- Prior art keywords
- inhibistors
- screening
- carboxyl methyltransferase
- dna encoding
- encoding same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4930497P | 1997-06-11 | 1997-06-11 | |
PCT/US1998/012328 WO1998056924A1 (en) | 1997-06-11 | 1998-06-11 | Prenylcysteine carboxyl methyltransferase, dna encoding same, and a method of screening for inhibitors thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL133129A0 true IL133129A0 (en) | 2001-03-19 |
Family
ID=21959118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13312998A IL133129A0 (en) | 1997-06-11 | 1998-06-11 | Prenylcysteine carboxyl methyltransferase dna encoding same and a method of screening for inhibistors thereof |
Country Status (9)
Country | Link |
---|---|
US (3) | US6184016B1 (de) |
EP (1) | EP1009833B1 (de) |
JP (1) | JP2002504827A (de) |
AT (1) | ATE380873T1 (de) |
AU (1) | AU8142598A (de) |
CA (1) | CA2293270A1 (de) |
DE (1) | DE69838843D1 (de) |
IL (1) | IL133129A0 (de) |
WO (1) | WO1998056924A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030181355A1 (en) * | 1992-05-29 | 2003-09-25 | Glenn Jeffrey S. | Method for inhibition of viral infection |
US5503973A (en) * | 1992-05-29 | 1996-04-02 | The Regents Of The University Of California | Method for inhibition of viral morphogenesis |
EP0910385A4 (de) * | 1996-04-15 | 1999-12-22 | Univ Pennsylvania | Sensibilisierung von zellen zur strahlen- und chemotherapie |
FR2773261B1 (fr) * | 1997-12-30 | 2000-01-28 | Commissariat Energie Atomique | Procede pour le transfert d'un film mince comportant une etape de creation d'inclusions |
EP1071788A1 (de) * | 1998-04-24 | 2001-01-31 | Onyx Pharmaceuticals, Inc. | Nukleinsäuren und polypeptide mit bezug zu einer farnesyl-bestimmten carboxy-methyltransferase |
US7384759B2 (en) * | 2000-12-11 | 2008-06-10 | The Salk Institute For Biological Studies | Methods and compositions for determinig enzymatic activity and specificity of chalcone O-methyltransferases |
US20030228688A1 (en) * | 2002-05-31 | 2003-12-11 | Isis Pharmaceuticals Inc. | Antisense modulation of isoprenylcysteine carboxyl methyltransferase expression |
US8586294B2 (en) * | 2004-05-18 | 2013-11-19 | The Board Of Trustees Of The Leland Stanford Junior University | Detection of protein translocation by beta-galactosidase reporter fragment complementation |
WO2014041349A1 (en) | 2012-09-12 | 2014-03-20 | Cancer Therapeutics Crc Pty Ltd | Tetrahydropyran-4-ylethylamino- or tetrahydropyranyl-4-ethyloxy-pyrimidines or -pyridazines as isoprenylcysteincarboxymethyl transferase inhibitors |
WO2018148224A1 (en) | 2017-02-07 | 2018-08-16 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (ple) car t cell tumor targeting (ctct) agents |
US11850262B2 (en) | 2017-02-28 | 2023-12-26 | Purdue Research Foundation | Compositions and methods for CAR T cell therapy |
CN112292138A (zh) | 2018-01-22 | 2021-01-29 | 西雅图儿童医院(Dba西雅图儿童研究所) | Car t细胞的使用方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5043268A (en) | 1990-05-04 | 1991-08-27 | The Trustees Of Princeton University | Substrates and inhibitors for prenyl cysteine methyltransferase enzymes |
US5202456A (en) | 1991-04-15 | 1993-04-13 | The President And Fellows Of Harvard College | Compounds for inhibition of protein methylation |
DK0692025T3 (da) | 1993-03-31 | 2002-02-11 | Cadus Pharmaceutical Corp | Gærceller, der er konstrueret således, at de producerer surrogater for proteiner i feromonsystemet, og anvendelser deraf |
CA2266543C (en) | 1996-09-24 | 2003-12-09 | Cadus Pharmaceutical Corporation | Methods and compositions for identifying receptor effectors |
US5876055A (en) | 1998-03-04 | 1999-03-02 | Fontaine; John P. K. | Automatic tolerance reducing greaseless fifth wheel using a wedge and jaw locking system that eliminates squirting |
EP1071788A1 (de) | 1998-04-24 | 2001-01-31 | Onyx Pharmaceuticals, Inc. | Nukleinsäuren und polypeptide mit bezug zu einer farnesyl-bestimmten carboxy-methyltransferase |
-
1998
- 1998-06-11 US US09/095,758 patent/US6184016B1/en not_active Expired - Lifetime
- 1998-06-11 CA CA002293270A patent/CA2293270A1/en not_active Abandoned
- 1998-06-11 EP EP98931260A patent/EP1009833B1/de not_active Expired - Lifetime
- 1998-06-11 IL IL13312998A patent/IL133129A0/xx unknown
- 1998-06-11 DE DE69838843T patent/DE69838843D1/de not_active Expired - Lifetime
- 1998-06-11 AU AU81425/98A patent/AU8142598A/en not_active Abandoned
- 1998-06-11 WO PCT/US1998/012328 patent/WO1998056924A1/en active IP Right Grant
- 1998-06-11 AT AT98931260T patent/ATE380873T1/de not_active IP Right Cessation
- 1998-06-11 JP JP50329599A patent/JP2002504827A/ja not_active Ceased
-
1999
- 1999-10-22 US US09/422,968 patent/US6232108B1/en not_active Expired - Lifetime
-
2000
- 2000-11-08 US US09/708,015 patent/US6432403B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU8142598A (en) | 1998-12-30 |
JP2002504827A (ja) | 2002-02-12 |
ATE380873T1 (de) | 2007-12-15 |
WO1998056924A1 (en) | 1998-12-17 |
CA2293270A1 (en) | 1998-12-17 |
EP1009833B1 (de) | 2007-12-12 |
US6184016B1 (en) | 2001-02-06 |
US6232108B1 (en) | 2001-05-15 |
US6432403B1 (en) | 2002-08-13 |
EP1009833A1 (de) | 2000-06-21 |
DE69838843D1 (de) | 2008-01-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL133129A0 (en) | Prenylcysteine carboxyl methyltransferase dna encoding same and a method of screening for inhibistors thereof | |
EP0799317B8 (de) | Verfahren zur sekretion thrombopoitin polypeptide | |
CY2586B2 (en) | Modulators of the function of FAS/APO1 receptors | |
AU3462899A (en) | Sequence and method for genetic engineering of proteins with cell membrane translocating activity | |
MX9703063A (es) | Compuestos de ester y acido boronico, su sintesis y usos. | |
AU1399495A (en) | Peptide and protein fusions to thioredoxin, thioredoxin-like molecules, and modified thioredoxin-like molecules | |
PT672141E (pt) | Metodos de preparacao de proteinas oligomericas soluveis | |
UA27706C2 (uk) | Спосіб одержання гетерологічного поліпептиду | |
AU4781493A (en) | Peptide and protein fusions to thioredoxin and thioredoxin-like molecules | |
BR9407583A (pt) | Processos para produzir uma proteina bcl-2 mutante para identificar agentes modulantes de bcl-2 candidatos um bcl-2 mutante e proteinas bcl-2 mutantes e para inibir a atividade repressora de morte de células de bcl-2 e polipeptideo bcl-2 mutante | |
EP0329127A3 (en) | Novel, signal peptides capable of functioning in yeasts and secretory expression of heterologous proteins using same | |
IL109262A0 (en) | Cell free system for protein synthesis and use of chaperon proteins therein | |
WO1994025590A3 (en) | Trichohyalin and transglutaminase-3 and methods of using same | |
AU2520595A (en) | Virosome-mediated intracellular delivery of therapeutic agents | |
TR200200048T2 (tr) | Otoproteolitik klevaj vasıtasıyla proteinlerin üretimi. | |
ES2168282T3 (es) | D-hidantoinasa recombinante, procedimiento para su preparacion y utilizacion. | |
AU2529584A (en) | Ultrapurification of factor ix and other vitamin k dependent proteins | |
IL129139A0 (en) | Vertebrate smoothened proteins | |
AU8991098A (en) | Regulation of protein secretion | |
Sandell et al. | The molecular weight of the cell-free translation product of αl (I) procollagen mRNA | |
EP1019526A4 (de) | Verfahren zur bestimmung der ionenkanalaktivität einer substanz | |
ZA944731B (en) | Hellcobacter pylorl haemagglutinin/protease protein nucleic acid encoding therefor and antibodies specific thereto | |
EP0991774A4 (de) | Verfahren zur erhöhung der proteinsekretion in eukaryotischen wirtszellen | |
AU2003200966B2 (en) | Yeast cells expressing modified G proteins and methods of use therefor | |
AU2003200966A1 (en) | Yeast cells expressing modified G proteins and methods of use therefor |