ES2168282T3 - D-hidantoinasa recombinante, procedimiento para su preparacion y utilizacion. - Google Patents

D-hidantoinasa recombinante, procedimiento para su preparacion y utilizacion.

Info

Publication number
ES2168282T3
ES2168282T3 ES94113110T ES94113110T ES2168282T3 ES 2168282 T3 ES2168282 T3 ES 2168282T3 ES 94113110 T ES94113110 T ES 94113110T ES 94113110 T ES94113110 T ES 94113110T ES 2168282 T3 ES2168282 T3 ES 2168282T3
Authority
ES
Spain
Prior art keywords
recombinant
hydantoinase
procedure
preparation
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94113110T
Other languages
English (en)
Inventor
Dr Helmut Burtscher
Gunter Lang
Dr Friedrich Popp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2168282T3 publication Critical patent/ES2168282T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UNA PROTEINA RECOMBINANTE CON ACTIVIDAD D QUE POSEE LA FRECUENCIA DE AMINOACIDOS SEQ ID NO 1, SE OBTIENE EN GRANDES CANTIDADES Y POSEE UNA ESTABILIDAD DE TEMPERATURA MEJORADA.
ES94113110T 1993-08-27 1994-08-23 D-hidantoinasa recombinante, procedimiento para su preparacion y utilizacion. Expired - Lifetime ES2168282T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4328829A DE4328829A1 (de) 1993-08-27 1993-08-27 Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ES2168282T3 true ES2168282T3 (es) 2002-06-16

Family

ID=6496152

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94113110T Expired - Lifetime ES2168282T3 (es) 1993-08-27 1994-08-23 D-hidantoinasa recombinante, procedimiento para su preparacion y utilizacion.

Country Status (6)

Country Link
US (2) US5523224A (es)
EP (1) EP0643133B1 (es)
JP (1) JP2546979B2 (es)
AT (1) ATE209252T1 (es)
DE (2) DE4328829A1 (es)
ES (1) ES2168282T3 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328829A1 (de) * 1993-08-27 1995-03-02 Boehringer Mannheim Gmbh Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung
KR100244066B1 (ko) * 1994-12-28 2000-02-01 후루따 다케시 D-N-카르바모일-α-아미노산의 제조법
US6524837B1 (en) * 1999-03-29 2003-02-25 California Institute Of Technology Hydantoinase variants with improved properties and their use for the production of amino acids
US6403357B1 (en) 2000-08-24 2002-06-11 National Science Council Thermostable D-hydantoinase and the application thereof
EP1258532A1 (en) * 2001-04-26 2002-11-20 National Science Council Thermostable D-hydantoinase from Bacillus circulans and the application thereof
JP4561010B2 (ja) * 2001-07-10 2010-10-13 味の素株式会社 Ｄ−ヒダントインハイドロラーゼをコードするｄｎａ、ｎ−カルバミル−ｄ−アミノ酸ハイドロラーゼをコードするｄｎａ、該遺伝子を含む組み換えｄｎａ、該組み換えｄｎａにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、ｄ−アミノ酸の製造方法
JP4561009B2 (ja) * 2001-07-10 2010-10-13 味の素株式会社 Ｄ−ヒダントインハイドロラーゼをコードするｄｎａ、ｎ−カルバミル−ｄ−アミノ酸ハイドロラーゼをコードするｄｎａ、該遺伝子を含む組み換えｄｎａ、該組み換えｄｎａにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、ｄ−アミノ酸の製造方法
US7247465B2 (en) * 2003-06-06 2007-07-24 Degussa Ag Screening process for hydantoin racemases
JP5159319B2 (ja) * 2005-12-12 2013-03-06 株式会社カネカ 新規ヒダントイナーゼ及びｎ−カルバモイル−ｄ−アミノ酸の製造方法
US11878381B2 (en) 2020-08-06 2024-01-23 Mate Precision Technologies Inc. Tooling base assembly
WO2022032178A1 (en) 2020-08-06 2022-02-10 Mate Precision Technologies Inc. Vise assembly

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3031151A1 (de) * 1980-08-18 1982-04-15 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von d-n-carbamoyl-(alpha)-aminosaeuren und mikroorganismen dafuer
IT1209495B (it) * 1984-02-02 1989-08-30 A San Donato Milanese Milano Procedimento per la preparazione di l-alfa-amminoacidi.
DE3535987A1 (de) * 1985-10-09 1987-04-23 Basf Ag Verfahren zur herstellung von meophilen mikroorganismen, die eine bei hoeherer temperatur aktive d-hydantoinase enthalten
WO1992010579A1 (en) * 1990-12-07 1992-06-25 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha PROCESS FOR PRODUCING D-α-AMINO ACID
JPH04325093A (ja) * 1991-04-23 1992-11-13 Nippon Soda Co Ltd 耐熱性ヒダントイナーゼ、及びそれをコードする遺伝子
DE4328829A1 (de) * 1993-08-27 1995-03-02 Boehringer Mannheim Gmbh Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung

Also Published As

Publication number Publication date
US5679571A (en) 1997-10-21
ATE209252T1 (de) 2001-12-15
JP2546979B2 (ja) 1996-10-23
EP0643133A2 (de) 1995-03-15
DE59409964D1 (de) 2002-01-03
US5523224A (en) 1996-06-04
JPH07163347A (ja) 1995-06-27
DE4328829A1 (de) 1995-03-02
EP0643133B1 (de) 2001-11-21
EP0643133A3 (de) 1995-05-24

Similar Documents

Publication Publication Date Title
ATE380875T1 (de) Chimäre proteine zur vermeidung der komplementaktivierung
CL2009002139A1 (es) Peptido sintetico que comprende la secuencia sec id no:6 y sec id no:7 de la proteina gp41 del virus vih con actividad antiretroviral.
DE69933216D1 (de) Erythropoietin-analog-menschliches serum-albumin fusionsprotein
IT8641628A0 (it) Bisturi criogenico e ultrasonico.
BR9407583A (pt) Processos para produzir uma proteina bcl-2 mutante para identificar agentes modulantes de bcl-2 candidatos um bcl-2 mutante e proteinas bcl-2 mutantes e para inibir a atividade repressora de morte de células de bcl-2 e polipeptideo bcl-2 mutante
ES2168282T3 (es) D-hidantoinasa recombinante, procedimiento para su preparacion y utilizacion.
DE68903576T2 (de) Signalpeptide, die in hefe wirksam sind und ihre verwendung zur sekretorischen expression von heterologen proteinen.
EP0875567A3 (de) Myc-bindende Zinkfinger-Proteine, ihre Herstellung und ihre Verwendung
MX18736A (es) Inhibidores retrovirales de proteasa y procedimiento para su preparacion.
ATE5314T1 (de) Pharmakologisch aktive peptide und deren zusammensetzungen.
DK0901526T3 (da) Cortistatin: neuropeptider, sammensætninger og metoder
OA08010A (fr) The synthesis of cyclopropane amino acids and peptides.
ES2058479T3 (es) Compuestos peptidicos.
DE69528531D1 (de) D-2-alkyltryptophan enthaltende polypeptide mit wachstumhormon freisetzender aktivitaet
TR200002101T2 (tr) Dondurulmuş gıda ürünü.
SE8502540D0 (sv) Stable dentifrice containing dextranase
ES8900018A1 (es) Procedimiento para la fabricacion de derivados aminoalcoholes peptidicos inhibidores de la renina y de las proteasas acidas
ES2149244T3 (es) Procedimientos para producir proteina c.
ATE103930T1 (de) Modifizierte proteine.
ES2080326T3 (es) Proteinas similares a ancrod, su obtencion y empleo.
ATE110775T1 (de) Verfahren zur herstellung von hirudin.
ES2126737T3 (es) Un procedimiento para la purificacion de material tensioactivo pulmonar usando fluidos supercriticos.
ATE310083T1 (de) Deprenyl induziertes protein
IT8720749A0 (it) Procedimento per la realizzazione di giunti impermeabili in diaframmi e diaframma relativo.
NO912072L (no) Rekombinante proteiner med adipsin- og komplement-d-aktiviteter.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 643133

Country of ref document: ES