ATE374198T1 - Substituierte pyrrolidine als ccr-3- rezeptorantagonisten - Google Patents

Substituierte pyrrolidine als ccr-3- rezeptorantagonisten

Info

Publication number
ATE374198T1
ATE374198T1 AT01271370T AT01271370T ATE374198T1 AT E374198 T1 ATE374198 T1 AT E374198T1 AT 01271370 T AT01271370 T AT 01271370T AT 01271370 T AT01271370 T AT 01271370T AT E374198 T1 ATE374198 T1 AT E374198T1
Authority
AT
Austria
Prior art keywords
ccr
receptor antagonists
substituted pyrrolidines
pyrrolidines
substituted
Prior art date
Application number
AT01271370T
Other languages
English (en)
Inventor
Denis Kertesz
Michael Roepel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE374198T1 publication Critical patent/ATE374198T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT01271370T 2000-12-19 2001-12-13 Substituierte pyrrolidine als ccr-3- rezeptorantagonisten ATE374198T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25658500P 2000-12-19 2000-12-19

Publications (1)

Publication Number Publication Date
ATE374198T1 true ATE374198T1 (de) 2007-10-15

Family

ID=22972794

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01271370T ATE374198T1 (de) 2000-12-19 2001-12-13 Substituierte pyrrolidine als ccr-3- rezeptorantagonisten

Country Status (15)

Country Link
US (2) US6552028B2 (de)
EP (1) EP1358181B1 (de)
JP (1) JP2004519443A (de)
KR (1) KR20030061455A (de)
CN (1) CN1239498C (de)
AR (1) AR035519A1 (de)
AT (1) ATE374198T1 (de)
AU (1) AU2002216107A1 (de)
BR (1) BR0116352A (de)
CA (1) CA2431767A1 (de)
DE (1) DE60130684T2 (de)
ES (1) ES2292530T3 (de)
MX (1) MXPA03005581A (de)
WO (1) WO2002050064A1 (de)
ZA (1) ZA200304530B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2006117631A (ru) * 2003-10-24 2007-12-10 Ф.Хоффманн-Ля Рош Аг (Ch) Антагонисты рецептора ссr3

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2143143A1 (en) * 1994-03-08 1995-09-09 Toshihiko Tanaka 3-phenylpyrrolidine derivatives
IL125658A0 (en) * 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
DE69938193D1 (de) * 1998-11-20 2008-04-03 Hoffmann La Roche Piperidin ccr-3 rezeptor-hemmer
JP3593037B2 (ja) * 1998-11-20 2004-11-24 エフ．ホフマン−ラ ロシュ アーゲー ピロリジン誘導体ｃｃｒ−３受容体アンタゴニスト
DE69926919D1 (de) 1998-12-18 2005-09-29 Bristol Myers Squibb Pharma Co N-ureidoalkylpiperidine als modulatoren der aktivität der chemokinrezeptoren
WO2000035876A1 (en) 1998-12-18 2000-06-22 Du Pont Pharmaceuticals Company 2-substituted-4-nitrogen heterocycles as modulators of chemokine receptor activity
WO2000035877A1 (en) 1998-12-18 2000-06-22 Du Pont Pharmaceuticals Company Heterocyclic piperidines as modulators of chemokine receptor activity
CA2350730A1 (en) 1998-12-18 2000-06-22 George V. Delucca N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
EP1156807A4 (de) 1998-12-18 2002-04-03 Du Pont Pharm Co N-ureidoalkylpiperidine als modulatoren der aktivität der chemokinrezeptoren
CA2348923A1 (en) 1998-12-18 2000-06-22 Dean A. Wacker N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
KR20010101287A (ko) 1998-12-18 2001-11-14 블레어 큐. 퍼거슨 케모킨 수용체 활성의 조절자로서 ｎ-우레이도알킬-피페리딘

Also Published As

Publication number Publication date
WO2002050064A1 (en) 2002-06-27
CA2431767A1 (en) 2002-06-27
CN1239498C (zh) 2006-02-01
DE60130684T2 (de) 2008-08-14
ZA200304530B (en) 2004-09-10
CN1481379A (zh) 2004-03-10
EP1358181B1 (de) 2007-09-26
US20030199532A1 (en) 2003-10-23
US6552028B2 (en) 2003-04-22
AR035519A1 (es) 2004-06-02
ES2292530T3 (es) 2008-03-16
AU2002216107A1 (en) 2002-07-01
MXPA03005581A (es) 2003-10-06
JP2004519443A (ja) 2004-07-02
BR0116352A (pt) 2003-12-02
DE60130684D1 (de) 2007-11-08
EP1358181A1 (de) 2003-11-05
US20020198255A1 (en) 2002-12-26
KR20030061455A (ko) 2003-07-18

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties