ATE372342T1 - Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva - Google Patents

Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva

Info

Publication number
ATE372342T1
ATE372342T1 AT03714897T AT03714897T ATE372342T1 AT E372342 T1 ATE372342 T1 AT E372342T1 AT 03714897 T AT03714897 T AT 03714897T AT 03714897 T AT03714897 T AT 03714897T AT E372342 T1 ATE372342 T1 AT E372342T1
Authority
AT
Austria
Prior art keywords
aminoisoxazoline
antidepressants
derivatives
substituted
substituted aminoisoxazoline
Prior art date
Application number
AT03714897T
Other languages
English (en)
Inventor
Jose Andres-Gil
Manuel Alcazar-Vaca
Margaretha Henrica Mari Bakker
Lucas Olivares Ana De
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE372342T1 publication Critical patent/ATE372342T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT03714897T 2002-04-02 2003-03-27 Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva ATE372342T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02076239 2002-04-02

Publications (1)

Publication Number Publication Date
ATE372342T1 true ATE372342T1 (de) 2007-09-15

Family

ID=28459528

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03714897T ATE372342T1 (de) 2002-04-02 2003-03-27 Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva

Country Status (24)

Country Link
US (1) US7265103B2 (de)
EP (1) EP1492796B1 (de)
JP (1) JP4580653B2 (de)
KR (1) KR20040093061A (de)
CN (1) CN100349897C (de)
AR (1) AR039207A1 (de)
AT (1) ATE372342T1 (de)
BR (1) BR0308309A (de)
CA (1) CA2480113C (de)
DE (1) DE60316134T2 (de)
DK (1) DK1492796T3 (de)
EA (1) EA008189B1 (de)
ES (1) ES2292949T3 (de)
HK (1) HK1080072A1 (de)
HR (1) HRP20040871A2 (de)
IL (2) IL164341A0 (de)
MX (1) MXPA04008626A (de)
NO (1) NO20044645L (de)
NZ (1) NZ536109A (de)
PL (1) PL211708B1 (de)
PT (1) PT1492796E (de)
TW (1) TWI286138B (de)
WO (1) WO2003082878A1 (de)
ZA (1) ZA200407904B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR040967A1 (es) 2002-08-12 2005-04-27 Janssen Pharmaceutica Nv Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
EP1532155B1 (de) * 2002-08-21 2008-02-27 Janssen Pharmaceutica N.V. C6- UND C9-SUBSTITUIERTE CHROMENO[4,3-c]ISOXAZOLINE UND IHRE VERWENDUNG ALS ANTI-DEPRESSIVA
US7635696B2 (en) 2004-11-26 2009-12-22 Janssen Pharmaceutica N.V. Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic activity
WO2009003867A1 (en) * 2007-07-03 2009-01-08 F. Hoffmann-La Roche Ag 4-imidazolines and their use as antidepressants
EP2781513A1 (de) 2009-03-10 2014-09-24 Takeda Pharmaceutical Company Limited Benzofuranderivate
US20130062732A1 (en) 2011-09-08 2013-03-14 International Business Machines Corporation Interconnect structures with functional components and methods for fabrication
CN105801510A (zh) * 2016-04-08 2016-07-27 李勇 一种治疗抑郁症的药物组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0361577B1 (de) 1988-09-19 1993-05-05 Akzo N.V. Tetrahydronaphthalin und Indan-Derivate
WO1997025317A1 (en) * 1996-01-05 1997-07-17 Hoechst Marion Roussel, Inc. 4,5-dihydronaphth[1,2-c]isoxazoles and derivatives thereof having cns activity
US6187774B1 (en) * 1996-03-04 2001-02-13 Yoshitomi Pharmaceutical Industries, Ltd. Fused heterocyclic compounds and pharmaceutical applications thereof
CA2437505C (en) * 2001-02-21 2010-02-09 Janssen Pharmaceutica N.V. Isoxazoline derivatives as anti-depressants
AR040967A1 (es) * 2002-08-12 2005-04-27 Janssen Pharmaceutica Nv Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
EP1532155B1 (de) * 2002-08-21 2008-02-27 Janssen Pharmaceutica N.V. C6- UND C9-SUBSTITUIERTE CHROMENO[4,3-c]ISOXAZOLINE UND IHRE VERWENDUNG ALS ANTI-DEPRESSIVA

Also Published As

Publication number Publication date
PL211708B1 (pl) 2012-06-29
DE60316134D1 (de) 2007-10-18
NZ536109A (en) 2006-06-30
TW200406414A (en) 2004-05-01
PL371630A1 (en) 2005-06-27
CN100349897C (zh) 2007-11-21
EP1492796B1 (de) 2007-09-05
AR039207A1 (es) 2005-02-09
US7265103B2 (en) 2007-09-04
CA2480113C (en) 2012-04-24
DE60316134T2 (de) 2008-05-29
IL164341A0 (en) 2005-12-18
AU2003219111A1 (en) 2003-10-13
HK1080072A1 (zh) 2006-04-21
KR20040093061A (ko) 2004-11-04
HRP20040871A2 (en) 2005-04-30
EA008189B1 (ru) 2007-04-27
ES2292949T3 (es) 2008-03-16
JP4580653B2 (ja) 2010-11-17
WO2003082878A1 (en) 2003-10-09
EP1492796A1 (de) 2005-01-05
DK1492796T3 (da) 2007-12-03
TWI286138B (en) 2007-09-01
EA200401297A1 (ru) 2005-02-24
JP2005522469A (ja) 2005-07-28
CN1642960A (zh) 2005-07-20
US20050222125A1 (en) 2005-10-06
PT1492796E (pt) 2007-11-16
MXPA04008626A (es) 2004-12-06
BR0308309A (pt) 2004-12-28
NO20044645L (no) 2004-10-27
IL164341A (en) 2009-06-15
ZA200407904B (en) 2005-10-20
CA2480113A1 (en) 2003-10-09

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