DK1492796T3 - Substituerede aminoisoxazolinderivater og deres anvendelse som antidepressive midler - Google Patents

Substituerede aminoisoxazolinderivater og deres anvendelse som antidepressive midler

Info

Publication number
DK1492796T3
DK1492796T3 DK03714897T DK03714897T DK1492796T3 DK 1492796 T3 DK1492796 T3 DK 1492796T3 DK 03714897 T DK03714897 T DK 03714897T DK 03714897 T DK03714897 T DK 03714897T DK 1492796 T3 DK1492796 T3 DK 1492796T3
Authority
DK
Denmark
Prior art keywords
aminoisoxazoline
antidepressants
derivatives
substituted
substituted aminoisoxazoline
Prior art date
Application number
DK03714897T
Other languages
English (en)
Inventor
Margaretha Henrica Mari Bakker
Jose Igancio Andres-Gil
Manuel Jes Alcazar-Vaca
Lucas Olivares Ana Isabel De
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1492796T3 publication Critical patent/DK1492796T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK03714897T 2002-04-02 2003-03-27 Substituerede aminoisoxazolinderivater og deres anvendelse som antidepressive midler DK1492796T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02076239 2002-04-02
PCT/EP2003/003245 WO2003082878A1 (en) 2002-04-02 2003-03-27 Substituted amino isoxazoline derivatives and their use as anti-depressants.

Publications (1)

Publication Number Publication Date
DK1492796T3 true DK1492796T3 (da) 2007-12-03

Family

ID=28459528

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03714897T DK1492796T3 (da) 2002-04-02 2003-03-27 Substituerede aminoisoxazolinderivater og deres anvendelse som antidepressive midler

Country Status (24)

Country Link
US (1) US7265103B2 (da)
EP (1) EP1492796B1 (da)
JP (1) JP4580653B2 (da)
KR (1) KR20040093061A (da)
CN (1) CN100349897C (da)
AR (1) AR039207A1 (da)
AT (1) ATE372342T1 (da)
BR (1) BR0308309A (da)
CA (1) CA2480113C (da)
DE (1) DE60316134T2 (da)
DK (1) DK1492796T3 (da)
EA (1) EA008189B1 (da)
ES (1) ES2292949T3 (da)
HK (1) HK1080072A1 (da)
HR (1) HRP20040871A2 (da)
IL (2) IL164341A0 (da)
MX (1) MXPA04008626A (da)
NO (1) NO20044645L (da)
NZ (1) NZ536109A (da)
PL (1) PL211708B1 (da)
PT (1) PT1492796E (da)
TW (1) TWI286138B (da)
WO (1) WO2003082878A1 (da)
ZA (1) ZA200407904B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR040967A1 (es) * 2002-08-12 2005-04-27 Janssen Pharmaceutica Nv Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
MY134287A (en) * 2002-08-21 2007-11-30 Janssen Pharmaceutica Nv C6- and c9-substituted isoxazoline derivatives and their use as anti-depressants
DE602005016836D1 (de) 2004-11-26 2009-11-05 Janssen Pharmaceutica Nv Chotischer und anxiolytischer aktivität
JP2010531836A (ja) * 2007-07-03 2010-09-30 エフ.ホフマン−ラ ロシュ アーゲー 4−イミダゾリン及びそれらの抗うつ剤としての使用
EP2406243B1 (en) 2009-03-10 2014-05-07 Takeda Pharmaceutical Company Limited Benzofuran derivatives
US20130062732A1 (en) 2011-09-08 2013-03-14 International Business Machines Corporation Interconnect structures with functional components and methods for fabrication
CN105801510A (zh) * 2016-04-08 2016-07-27 李勇 一种治疗抑郁症的药物组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68906340T2 (de) 1988-09-19 1993-08-12 Akzo Nv Tetrahydronaphthalin und indan-derivate.
WO1997025317A1 (en) * 1996-01-05 1997-07-17 Hoechst Marion Roussel, Inc. 4,5-dihydronaphth[1,2-c]isoxazoles and derivatives thereof having cns activity
US6187774B1 (en) * 1996-03-04 2001-02-13 Yoshitomi Pharmaceutical Industries, Ltd. Fused heterocyclic compounds and pharmaceutical applications thereof
JP3953424B2 (ja) * 2001-02-21 2007-08-08 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗うつ薬としてのイソキサゾリン誘導体
AR040967A1 (es) * 2002-08-12 2005-04-27 Janssen Pharmaceutica Nv Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
MY134287A (en) * 2002-08-21 2007-11-30 Janssen Pharmaceutica Nv C6- and c9-substituted isoxazoline derivatives and their use as anti-depressants

Also Published As

Publication number Publication date
IL164341A0 (en) 2005-12-18
BR0308309A (pt) 2004-12-28
MXPA04008626A (es) 2004-12-06
ES2292949T3 (es) 2008-03-16
KR20040093061A (ko) 2004-11-04
PT1492796E (pt) 2007-11-16
EP1492796A1 (en) 2005-01-05
US7265103B2 (en) 2007-09-04
PL211708B1 (pl) 2012-06-29
US20050222125A1 (en) 2005-10-06
JP4580653B2 (ja) 2010-11-17
JP2005522469A (ja) 2005-07-28
PL371630A1 (en) 2005-06-27
TW200406414A (en) 2004-05-01
CA2480113A1 (en) 2003-10-09
HK1080072A1 (zh) 2006-04-21
NZ536109A (en) 2006-06-30
EA008189B1 (ru) 2007-04-27
TWI286138B (en) 2007-09-01
CN1642960A (zh) 2005-07-20
CA2480113C (en) 2012-04-24
WO2003082878A1 (en) 2003-10-09
CN100349897C (zh) 2007-11-21
AR039207A1 (es) 2005-02-09
HRP20040871A2 (en) 2005-04-30
EA200401297A1 (ru) 2005-02-24
NO20044645L (no) 2004-10-27
DE60316134D1 (de) 2007-10-18
AU2003219111A1 (en) 2003-10-13
ATE372342T1 (de) 2007-09-15
ZA200407904B (en) 2005-10-20
DE60316134T2 (de) 2008-05-29
IL164341A (en) 2009-06-15
EP1492796B1 (en) 2007-09-05

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