DK1492796T3 - Substituerede aminoisoxazolinderivater og deres anvendelse som antidepressive midler - Google Patents

Substituerede aminoisoxazolinderivater og deres anvendelse som antidepressive midler

Info

Publication number
DK1492796T3
DK1492796T3 DK03714897T DK03714897T DK1492796T3 DK 1492796 T3 DK1492796 T3 DK 1492796T3 DK 03714897 T DK03714897 T DK 03714897T DK 03714897 T DK03714897 T DK 03714897T DK 1492796 T3 DK1492796 T3 DK 1492796T3
Authority
DK
Denmark
Prior art keywords
aminoisoxazoline
antidepressants
derivatives
substituted
substituted aminoisoxazoline
Prior art date
Application number
DK03714897T
Other languages
English (en)
Inventor
Margaretha Henrica Mari Bakker
Jose Igancio Andres-Gil
Manuel Jes Alcazar-Vaca
Lucas Olivares Ana Isabel De
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1492796T3 publication Critical patent/DK1492796T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK03714897T 2002-04-02 2003-03-27 Substituerede aminoisoxazolinderivater og deres anvendelse som antidepressive midler DK1492796T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02076239 2002-04-02
PCT/EP2003/003245 WO2003082878A1 (en) 2002-04-02 2003-03-27 Substituted amino isoxazoline derivatives and their use as anti-depressants.

Publications (1)

Publication Number Publication Date
DK1492796T3 true DK1492796T3 (da) 2007-12-03

Family

ID=28459528

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03714897T DK1492796T3 (da) 2002-04-02 2003-03-27 Substituerede aminoisoxazolinderivater og deres anvendelse som antidepressive midler

Country Status (24)

Country Link
US (1) US7265103B2 (da)
EP (1) EP1492796B1 (da)
JP (1) JP4580653B2 (da)
KR (1) KR20040093061A (da)
CN (1) CN100349897C (da)
AR (1) AR039207A1 (da)
AT (1) ATE372342T1 (da)
BR (1) BR0308309A (da)
CA (1) CA2480113C (da)
DE (1) DE60316134T2 (da)
DK (1) DK1492796T3 (da)
EA (1) EA008189B1 (da)
ES (1) ES2292949T3 (da)
HK (1) HK1080072A1 (da)
HR (1) HRP20040871A2 (da)
IL (2) IL164341A0 (da)
MX (1) MXPA04008626A (da)
NO (1) NO20044645L (da)
NZ (1) NZ536109A (da)
PL (1) PL211708B1 (da)
PT (1) PT1492796E (da)
TW (1) TWI286138B (da)
WO (1) WO2003082878A1 (da)
ZA (1) ZA200407904B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200409777A (en) * 2002-08-12 2004-06-16 Janssen Pharmaceutica Nv C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
DE60319388T2 (de) * 2002-08-21 2009-02-19 Janssen Pharmaceutica N.V. C6- und C9-substituierte Chromeno[4,3-c]Isoxazoline und ihre Verwendung als Anti-Depressiva
JP2008521771A (ja) 2004-11-26 2008-06-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 改良された抗精神病活性および抗不安症活性を有するイソキサゾリン−インドール誘導体
MX2009013745A (es) * 2007-07-03 2010-01-26 Hoffmann La Roche 4-imidazolinas y su uso como antidepresivos.
ES2487616T3 (es) 2009-03-10 2014-08-22 Takeda Pharmaceutical Company Limited Derivados de benzofurano
US20130062732A1 (en) 2011-09-08 2013-03-14 International Business Machines Corporation Interconnect structures with functional components and methods for fabrication
CN105801510A (zh) * 2016-04-08 2016-07-27 李勇 一种治疗抑郁症的药物组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2055011T3 (es) 1988-09-19 1994-08-16 Akzo Nv Un procedimiento para la preparacion de derivados de tetrahidronaftaleno e indano.
WO1997025317A1 (en) * 1996-01-05 1997-07-17 Hoechst Marion Roussel, Inc. 4,5-dihydronaphth[1,2-c]isoxazoles and derivatives thereof having cns activity
US6187774B1 (en) 1996-03-04 2001-02-13 Yoshitomi Pharmaceutical Industries, Ltd. Fused heterocyclic compounds and pharmaceutical applications thereof
KR100848898B1 (ko) 2001-02-21 2008-07-29 얀센 파마슈티카 엔.브이. 항우울제로서 이속사졸린 유도체
TW200409777A (en) * 2002-08-12 2004-06-16 Janssen Pharmaceutica Nv C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
DE60319388T2 (de) * 2002-08-21 2009-02-19 Janssen Pharmaceutica N.V. C6- und C9-substituierte Chromeno[4,3-c]Isoxazoline und ihre Verwendung als Anti-Depressiva

Also Published As

Publication number Publication date
MXPA04008626A (es) 2004-12-06
US7265103B2 (en) 2007-09-04
ZA200407904B (en) 2005-10-20
ES2292949T3 (es) 2008-03-16
TWI286138B (en) 2007-09-01
IL164341A0 (en) 2005-12-18
PL371630A1 (en) 2005-06-27
CN100349897C (zh) 2007-11-21
BR0308309A (pt) 2004-12-28
CA2480113C (en) 2012-04-24
NZ536109A (en) 2006-06-30
PL211708B1 (pl) 2012-06-29
DE60316134D1 (de) 2007-10-18
TW200406414A (en) 2004-05-01
JP2005522469A (ja) 2005-07-28
EA200401297A1 (ru) 2005-02-24
EP1492796A1 (en) 2005-01-05
DE60316134T2 (de) 2008-05-29
NO20044645L (no) 2004-10-27
IL164341A (en) 2009-06-15
JP4580653B2 (ja) 2010-11-17
US20050222125A1 (en) 2005-10-06
HK1080072A1 (zh) 2006-04-21
EA008189B1 (ru) 2007-04-27
CN1642960A (zh) 2005-07-20
ATE372342T1 (de) 2007-09-15
AR039207A1 (es) 2005-02-09
HRP20040871A2 (en) 2005-04-30
CA2480113A1 (en) 2003-10-09
KR20040093061A (ko) 2004-11-04
PT1492796E (pt) 2007-11-16
WO2003082878A1 (en) 2003-10-09
EP1492796B1 (en) 2007-09-05
AU2003219111A1 (en) 2003-10-13

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