ATE366245T1 - Benzothia(dia)zinderivate und ihre verwendung als ampa-modulatoren - Google Patents

Benzothia(dia)zinderivate und ihre verwendung als ampa-modulatoren

Info

Publication number
ATE366245T1
ATE366245T1 AT02805407T AT02805407T ATE366245T1 AT E366245 T1 ATE366245 T1 AT E366245T1 AT 02805407 T AT02805407 T AT 02805407T AT 02805407 T AT02805407 T AT 02805407T AT E366245 T1 ATE366245 T1 AT E366245T1
Authority
AT
Austria
Prior art keywords
benzothia
dia
ampa modulators
zine derivatives
zine
Prior art date
Application number
AT02805407T
Other languages
English (en)
Inventor
Alex Cordi
Patrice Desos
Pierre Lestage
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of ATE366245T1 publication Critical patent/ATE366245T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02805407T 2001-12-21 2002-12-20 Benzothia(dia)zinderivate und ihre verwendung als ampa-modulatoren ATE366245T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0116622A FR2833950B1 (fr) 2001-12-21 2001-12-21 Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ATE366245T1 true ATE366245T1 (de) 2007-07-15

Family

ID=8870810

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02805407T ATE366245T1 (de) 2001-12-21 2002-12-20 Benzothia(dia)zinderivate und ihre verwendung als ampa-modulatoren

Country Status (26)

Country Link
US (1) US7250411B2 (de)
EP (1) EP1456189B1 (de)
JP (1) JP2005517668A (de)
KR (1) KR100606606B1 (de)
CN (1) CN1606550A (de)
AR (1) AR038029A1 (de)
AT (1) ATE366245T1 (de)
AU (1) AU2002365017B2 (de)
BR (1) BR0215145A (de)
CA (1) CA2471057A1 (de)
DE (1) DE60221041T2 (de)
DK (1) DK1456189T3 (de)
EA (1) EA007271B1 (de)
ES (1) ES2289182T3 (de)
FR (1) FR2833950B1 (de)
GE (1) GEP20063758B (de)
HU (1) HUP0402584A2 (de)
MA (1) MA27089A1 (de)
MX (1) MXPA04005838A (de)
NO (1) NO20042684L (de)
NZ (1) NZ533330A (de)
PL (1) PL369767A1 (de)
PT (1) PT1456189E (de)
UA (1) UA78743C2 (de)
WO (1) WO2003053947A1 (de)
ZA (1) ZA200404296B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2856064B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2856065B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2865474B1 (fr) * 2004-01-26 2008-06-13 Servier Lab Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2877342B1 (fr) * 2004-11-03 2007-01-26 Servier Lab Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2877338B1 (fr) * 2004-11-03 2007-01-26 Servier Lab Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB0724625D0 (en) * 2007-12-18 2008-01-30 Glaxo Group Ltd Novel compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3957093A (en) * 1992-04-15 1993-11-18 Rhone-Poulenc Rorer S.A. 3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxyl ic acid derivatives, preparation thereof and drugs containing same
AU4345297A (en) * 1996-09-17 1998-04-14 Regents Of The University Of California, The Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor
CA2320354A1 (en) * 1998-02-18 1999-08-26 Neurosearch A/S Novel compounds and their use as positive ampa receptor modulators
FR2801587B1 (fr) * 1999-11-30 2002-01-11 Adir Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
DE60221041T2 (de) 2008-04-10
AU2002365017A1 (en) 2003-07-09
EP1456189B1 (de) 2007-07-04
EP1456189A1 (de) 2004-09-15
BR0215145A (pt) 2004-10-19
AR038029A1 (es) 2004-12-22
DE60221041D1 (de) 2007-08-16
EA200400756A1 (ru) 2004-10-28
KR100606606B1 (ko) 2006-08-01
GEP20063758B (en) 2006-02-27
FR2833950B1 (fr) 2005-12-16
PT1456189E (pt) 2007-09-20
PL369767A1 (en) 2005-05-02
AU2002365017B2 (en) 2007-12-13
MXPA04005838A (es) 2004-09-10
NO20042684L (no) 2004-06-25
CN1606550A (zh) 2005-04-13
FR2833950A1 (fr) 2003-06-27
NZ533330A (en) 2006-05-26
JP2005517668A (ja) 2005-06-16
KR20040065276A (ko) 2004-07-21
HUP0402584A2 (hu) 2005-04-28
ZA200404296B (en) 2005-06-01
DK1456189T3 (da) 2007-11-05
ES2289182T3 (es) 2008-02-01
UA78743C2 (en) 2007-04-25
WO2003053947A1 (fr) 2003-07-03
MA27089A1 (fr) 2004-12-20
CA2471057A1 (fr) 2003-07-03
US20050014744A1 (en) 2005-01-20
US7250411B2 (en) 2007-07-31
EA007271B1 (ru) 2006-08-25

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee