ATE364700T1 - Bestandteil von bromelain - Google Patents

Bestandteil von bromelain

Info

Publication number
ATE364700T1
ATE364700T1 AT98907054T AT98907054T ATE364700T1 AT E364700 T1 ATE364700 T1 AT E364700T1 AT 98907054 T AT98907054 T AT 98907054T AT 98907054 T AT98907054 T AT 98907054T AT E364700 T1 ATE364700 T1 AT E364700T1
Authority
AT
Austria
Prior art keywords
bromelain
component
map kinase
activation
comosain
Prior art date
Application number
AT98907054T
Other languages
English (en)
Inventor
Tracey Mynott
Christian Engwerda
Keith Peek
Original Assignee
Sarantis Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9703850.9A external-priority patent/GB9703850D0/en
Priority claimed from GBGB9703827.7A external-priority patent/GB9703827D0/en
Priority claimed from GBGB9704252.7A external-priority patent/GB9704252D0/en
Priority claimed from GBGB9706119.6A external-priority patent/GB9706119D0/en
Application filed by Sarantis Pty Ltd filed Critical Sarantis Pty Ltd
Application granted granted Critical
Publication of ATE364700T1 publication Critical patent/ATE364700T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472Cysteine endopeptidases (3.4.22)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/63Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
AT98907054T 1997-02-25 1998-02-25 Bestandteil von bromelain ATE364700T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9703850.9A GB9703850D0 (en) 1997-02-25 1997-02-25 Novel protein
GBGB9703827.7A GB9703827D0 (en) 1997-02-25 1997-02-25 Novel protein
GBGB9704252.7A GB9704252D0 (en) 1997-02-28 1997-02-28 Novel protein
GBGB9706119.6A GB9706119D0 (en) 1997-03-25 1997-03-25 Novel protein

Publications (1)

Publication Number Publication Date
ATE364700T1 true ATE364700T1 (de) 2007-07-15

Family

ID=27451608

Family Applications (3)

Application Number Title Priority Date Filing Date
AT07024577T ATE533842T1 (de) 1997-02-25 1998-02-25 Bromelainbestandteil
AT98907053T ATE382084T1 (de) 1997-02-25 1998-02-25 Bromelinbestandteil
AT98907054T ATE364700T1 (de) 1997-02-25 1998-02-25 Bestandteil von bromelain

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT07024577T ATE533842T1 (de) 1997-02-25 1998-02-25 Bromelainbestandteil
AT98907053T ATE382084T1 (de) 1997-02-25 1998-02-25 Bromelinbestandteil

Country Status (8)

Country Link
EP (4) EP1908823B1 (de)
JP (3) JP4651756B2 (de)
CN (2) CN1204258C (de)
AT (3) ATE533842T1 (de)
AU (2) AU6303798A (de)
DE (2) DE69838909T2 (de)
ES (4) ES2297878T3 (de)
WO (2) WO1998038291A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020102253A1 (en) 1997-02-25 2002-08-01 Mynott Tracey Lehanne Component of bromelain
CN1252101A (zh) 1997-02-25 2000-05-03 科特克斯(英国)有限公司 菠萝蛋白酶成分
ES2182356T3 (es) * 1998-07-15 2003-03-01 Ursapharm Arzneimittel Gmbh Uso de proteasas de bromelaina para inhibir la coagulacion de la sangre.
AU2845400A (en) * 1998-12-24 2000-07-31 Phairson Medical Inc. Treatment and prevention of immune rejection reactions
US6977245B2 (en) * 1999-04-12 2005-12-20 The United States Of America As Represented By The Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
EP2316482A1 (de) * 2001-03-19 2011-05-04 Intercell USA, Inc. Transkutane Immunostimulierung
WO2017031299A1 (en) 2015-08-20 2017-02-23 Anatara Lifesciences Limited Enzymatic fractions with anti-inflammatory activity
AU2021237876A1 (en) * 2020-03-20 2022-10-13 Novel Concepts Medical Ltd Compositions and methods for treating and preventing a coronavirus infection

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8724728D0 (en) * 1987-10-22 1987-11-25 Genzyme Corp Cysteine proteinase
IL105699A0 (en) * 1992-06-26 1993-09-22 Genzyme Corp Hydrophilic creams for delivery of therapeutic agents
SG42846A1 (en) * 1992-06-30 1997-10-17 Cortecs Ltd Use of enzymes especially bromelain in the treatment of diarrhoea
US5387517A (en) * 1994-03-23 1995-02-07 Ethicon, Inc. Thiol activated protease from stem bromelain for treating devitalized tissue
GB9412711D0 (en) * 1994-06-24 1994-08-17 Cortecs Ltd Medical use of bromelain

Also Published As

Publication number Publication date
JP4673454B2 (ja) 2011-04-20
CN1204258C (zh) 2005-06-01
ES2403433T3 (es) 2013-05-17
EP0996710B1 (de) 2007-12-26
DE69838909D1 (de) 2008-02-07
ES2288762T3 (es) 2008-01-16
EP1908823B1 (de) 2011-11-16
DE69837923D1 (de) 2007-07-26
ES2297878T3 (es) 2008-05-01
JP2002512509A (ja) 2002-04-23
EP1012304A1 (de) 2000-06-28
CN100400659C (zh) 2008-07-09
JP2001513635A (ja) 2001-09-04
ATE382084T1 (de) 2008-01-15
JP4651756B2 (ja) 2011-03-16
EP0996710A1 (de) 2000-05-03
WO1998038319A1 (en) 1998-09-03
EP1012304B1 (de) 2007-06-13
AU6303798A (en) 1998-09-18
EP1865055B1 (de) 2012-12-05
CN1249002A (zh) 2000-03-29
WO1998038291A1 (en) 1998-09-03
CN1252096A (zh) 2000-05-03
JP2010143945A (ja) 2010-07-01
ES2377539T3 (es) 2012-03-28
AU6303698A (en) 1998-09-18
DE69837923T2 (de) 2008-02-14
ATE533842T1 (de) 2011-12-15
DE69838909T2 (de) 2009-01-08
EP1908823A1 (de) 2008-04-09
EP1865055A1 (de) 2007-12-12

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