ATE360817T1 - Verbindungen und verfahren zur nachweiss von karzinomen und deren vorstufen - Google Patents
Verbindungen und verfahren zur nachweiss von karzinomen und deren vorstufenInfo
- Publication number
- ATE360817T1 ATE360817T1 AT02102814T AT02102814T ATE360817T1 AT E360817 T1 ATE360817 T1 AT E360817T1 AT 02102814 T AT02102814 T AT 02102814T AT 02102814 T AT02102814 T AT 02102814T AT E360817 T1 ATE360817 T1 AT E360817T1
- Authority
- AT
- Austria
- Prior art keywords
- carcinomas
- detection
- methods
- compounds
- treatment
- Prior art date
Links
- 201000009030 Carcinoma Diseases 0.000 title abstract 5
- 239000002243 precursor Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000003902 lesion Effects 0.000 abstract 5
- 238000001514 detection method Methods 0.000 abstract 4
- 102000016911 Deoxyribonucleases Human genes 0.000 abstract 2
- 108010053770 Deoxyribonucleases Proteins 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000013399 early diagnosis Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
- 230000004960 subcellular localization Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
- G01N2333/922—Ribonucleases (RNAses); Deoxyribonucleases (DNAses)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Marine Sciences & Fisheries (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02102814A EP1431762B1 (en) | 2002-12-18 | 2002-12-18 | Compounds and methods for detection of carcinomas and their precursor lesions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE360817T1 true ATE360817T1 (de) | 2007-05-15 |
Family
ID=32338157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02102814T ATE360817T1 (de) | 2002-12-18 | 2002-12-18 | Verbindungen und verfahren zur nachweiss von karzinomen und deren vorstufen |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20060121485A1 (enExample) |
| EP (1) | EP1431762B1 (enExample) |
| JP (1) | JP4527544B2 (enExample) |
| CN (1) | CN1726393B (enExample) |
| AT (1) | ATE360817T1 (enExample) |
| AU (1) | AU2003302964A1 (enExample) |
| CA (1) | CA2510150C (enExample) |
| DE (1) | DE60219809T2 (enExample) |
| ES (1) | ES2286201T3 (enExample) |
| WO (1) | WO2004055514A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1431762B1 (en) * | 2002-12-18 | 2007-04-25 | Coy, Johannes F., Dr. | Compounds and methods for detection of carcinomas and their precursor lesions |
| US8710012B2 (en) * | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
| US8388951B2 (en) | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
| ES2524458T3 (es) | 2006-10-18 | 2014-12-09 | Periness Ltd. | DNasa para el tratamiento de la subfertilidad masculina |
| JP2008253188A (ja) * | 2007-04-04 | 2008-10-23 | Tokyo Univ Of Science | エンドサイトーシス依存性ｄｎａ取り込み抑制剤、エンドサイトーシス依存性ｄｎａ取り込み促進剤、ウイルス感染阻害剤、ウイルス感染予防剤、及びウイルス感染促進剤、並びに、遺伝子マーカー、モノクローナル抗体、ハイブリドーマ、及びそれらの使用方法。 |
| US7734161B2 (en) * | 2007-04-19 | 2010-06-08 | Avago Technologies Ecbu Ip (Singapore) Pte. Ltd. | Image stabilization with adaptive shutter control |
| US9360489B2 (en) * | 2007-06-11 | 2016-06-07 | Sutter Bay Hospitals | Method and kit for dynamic gene expression monitoring |
| US10617743B2 (en) | 2014-06-19 | 2020-04-14 | Cls Therapeutics Limited | Method to improve safety and efficacy of anti-cancer therapy |
| CN104267011A (zh) * | 2014-09-23 | 2015-01-07 | 中国科学院东北地理与农业生态研究所 | 一种转基因羊卵母细胞的筛选方法 |
| ES2799515T3 (es) | 2015-05-22 | 2020-12-18 | Dmitry Dmitrievich Genkin | ADN extracelular como una diana terapéutica en la neurodegeneración |
| CN107677822A (zh) * | 2016-08-02 | 2018-02-09 | 北京金沐医疗科技有限公司 | 检测肿瘤标志物的荧光细胞计数检测试剂盒 |
| CN107677820A (zh) * | 2016-08-02 | 2018-02-09 | 北京金沐医疗科技有限公司 | 一种检测肿瘤抗原的试剂盒及其检测方法 |
| CN107677823A (zh) * | 2016-08-02 | 2018-02-09 | 北京金沐医疗科技有限公司 | 一种用于检测肿瘤抗原的蛋白芯片试剂盒及其检测方法 |
| JP2021510539A (ja) | 2018-01-16 | 2021-04-30 | シーエルエス セラピューティクス リミテッドＣＬＳ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ | デオキシリボヌクレアーゼ（ＤＮａｓｅ）活性を有する酵素の肝臓発現による疾患の処置 |
| CN109406771B (zh) * | 2018-10-26 | 2023-04-07 | 安徽大千生物工程有限公司 | 胱抑素c胶乳增强比浊法检测试剂盒及其制备使用方法 |
| WO2020223265A1 (en) * | 2019-04-28 | 2020-11-05 | Essenlix Corporation | Rapid pathology/cytology without wash |
| CN113314220B (zh) * | 2021-07-28 | 2021-11-02 | 江苏为真生物医药技术股份有限公司 | 疾病病程监控系统、计算机可读存储介质以及电子设备 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19521046C1 (de) * | 1995-06-09 | 1996-08-08 | Deutsches Krebsforsch | Protein mit DNase-Aktivität |
| WO2000052204A2 (en) * | 1999-02-22 | 2000-09-08 | Orntoft Torben F | Gene expression in bladder tumors |
| US20020052308A1 (en) * | 1999-03-12 | 2002-05-02 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| EP1249495A1 (de) * | 2001-04-11 | 2002-10-16 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Murine DNase X, diese enthaltendes Arzneimittel und nicht-menschliches Säugetier mit verändertem DNase X-Gen |
| CA2466483A1 (en) * | 2001-11-07 | 2003-07-03 | John D. Shaughnessy | Diagnosis prognosis and identification of potential therapeutic targets of multiple myeloma based on gene expression profiling |
| CA2499709A1 (en) * | 2002-06-19 | 2003-12-31 | Yoichi Furukawa | Method for diagnosis of colorectal tumors |
| EP1431762B1 (en) * | 2002-12-18 | 2007-04-25 | Coy, Johannes F., Dr. | Compounds and methods for detection of carcinomas and their precursor lesions |
-
2002
- 2002-12-18 EP EP02102814A patent/EP1431762B1/en not_active Expired - Lifetime
- 2002-12-18 AT AT02102814T patent/ATE360817T1/de active
- 2002-12-18 ES ES02102814T patent/ES2286201T3/es not_active Expired - Lifetime
- 2002-12-18 DE DE60219809T patent/DE60219809T2/de not_active Expired - Lifetime
-
2003
- 2003-12-16 WO PCT/EP2003/051028 patent/WO2004055514A1/en not_active Ceased
- 2003-12-16 AU AU2003302964A patent/AU2003302964A1/en not_active Abandoned
- 2003-12-16 JP JP2004560521A patent/JP4527544B2/ja not_active Expired - Lifetime
- 2003-12-16 CA CA2510150A patent/CA2510150C/en not_active Expired - Lifetime
- 2003-12-16 CN CN2003801065094A patent/CN1726393B/zh not_active Expired - Fee Related
- 2003-12-16 US US10/539,233 patent/US20060121485A1/en not_active Abandoned
-
2007
- 2007-10-29 US US11/927,274 patent/US8759004B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2286201T3 (es) | 2007-12-01 |
| AU2003302964A1 (en) | 2004-07-09 |
| JP4527544B2 (ja) | 2010-08-18 |
| DE60219809T2 (de) | 2008-01-17 |
| CN1726393A (zh) | 2006-01-25 |
| EP1431762B1 (en) | 2007-04-25 |
| CA2510150C (en) | 2017-11-07 |
| EP1431762A1 (en) | 2004-06-23 |
| WO2004055514A1 (en) | 2004-07-01 |
| US20060121485A1 (en) | 2006-06-08 |
| CA2510150A1 (en) | 2004-07-01 |
| US8759004B2 (en) | 2014-06-24 |
| JP2006510363A (ja) | 2006-03-30 |
| DE60219809D1 (de) | 2007-06-06 |
| CN1726393B (zh) | 2010-04-28 |
| US20080234393A1 (en) | 2008-09-25 |
| HK1086331A1 (zh) | 2006-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE360817T1 (de) | Verbindungen und verfahren zur nachweiss von karzinomen und deren vorstufen | |
| DE60042695D1 (de) | Verfahren für den nachweis von erkrankungen | |
| DE60041355D1 (de) | Verfahren zur detektion von erkrankungen | |
| ATE333517T1 (de) | Verfahren und sondenset zur erkennung von krebs | |
| DE60029092D1 (de) | Verfahren zur detektion von nukleinsäuren, welche auf krebs hinweisen | |
| DE60319641D1 (de) | Methode zur Anwendung Molekulare Konstrukte zur Detektion biochemischer Reaktionen | |
| ATE275642T1 (de) | Verfahren zur diagnose von krebs | |
| ATE347306T1 (de) | Vorrichtung und verfahren zur zufuhr und analyse von einer physiologischen flüssigkeit | |
| DE69938662D1 (de) | Spurendetektion von analyten mit hilfe artifizieller olfaktometrie | |
| DE60000583D1 (de) | Verfahren zur identifizierung und/oder quantifizierung einer zielverbindung | |
| WO2002086448A3 (en) | Detection of microsatellite instability and its use in diagnosis of tumors | |
| ATE282831T1 (de) | Verfahren zur diagnose von sepsis unter bestimmung löslicher cytokeratinfragmente | |
| DE60325382D1 (de) | Verfahren zur diagnose von gebärmutterhalskrebs | |
| ATE422671T1 (de) | Verfahren zur diagnose von morbus alzheimer | |
| DE60331857D1 (de) | Markerproteine zur diagnose einer lebererkrankung und verfahren zur diagnose einer lebererkrankung damit | |
| ATE429495T1 (de) | Nukleinsäuren für die apoptose von krebszellen | |
| Casula et al. | An innovative PCR-free approach for DNA methylation measure: An application for early colorectal cancer detection by means of an organic biosensor | |
| ATE272214T1 (de) | Verfahren zur diagnose von sepsis unter bestimmung von s100b | |
| ATE272215T1 (de) | Verfahren zur diagnose von sepsis unter bestimmung von ca 19-9 | |
| DE60223149D1 (de) | Nachweisverfahren mit biochip | |
| DE50105971D1 (de) | Verfahren zur Diagnose von Sepsis unter Bestimmung von CA 125 | |
| MX2007008984A (es) | Marcadores de cancer y metodos de deteccion. | |
| ATE494390T1 (de) | Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen | |
| ATE386263T1 (de) | Verfahren und vorrichtung zum analysieren von chemischen oder biologischen proben | |
| DE50214861D1 (de) | Verfahren zum erfassen von nukleinsäuremolekülen mittels mindestens einer einheit zum immobilisieren von nukleinsäuremolekülen und biosensor zum erfassen von nukleinsäuremolekülen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1431762 Country of ref document: EP |