JP4527544B2 - 癌およびその前駆病変の検出のための化合物および方法 - Google Patents

癌およびその前駆病変の検出のための化合物および方法 Download PDF

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JP4527544B2
JP4527544B2 JP2004560521A JP2004560521A JP4527544B2 JP 4527544 B2 JP4527544 B2 JP 4527544B2 JP 2004560521 A JP2004560521 A JP 2004560521A JP 2004560521 A JP2004560521 A JP 2004560521A JP 4527544 B2 JP4527544 B2 JP 4527544B2
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dnase
cancer
detection
nucleic acid
polypeptide
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JP2006510363A5 (enExample
JP2006510363A (ja
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コイ，ヨハネス
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G01N2333/922—Ribonucleases (RNAses); Deoxyribonucleases (DNAses)

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
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JP2004560521A 2002-12-18 2003-12-16 癌およびその前駆病変の検出のための化合物および方法 Expired - Lifetime JP4527544B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02102814A EP1431762B1 (en) 2002-12-18 2002-12-18 Compounds and methods for detection of carcinomas and their precursor lesions
PCT/EP2003/051028 WO2004055514A1 (en) 2002-12-18 2003-12-16 Compounds and methods for detection of carcinomas and their precursor lesions

Publications (3)

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JP2006510363A JP2006510363A (ja) 2006-03-30
JP2006510363A5 JP2006510363A5 (enExample) 2006-10-19
JP4527544B2 true JP4527544B2 (ja) 2010-08-18

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JP2004560521A Expired - Lifetime JP4527544B2 (ja) 2002-12-18 2003-12-16 癌およびその前駆病変の検出のための化合物および方法

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US (2) US20060121485A1 (enExample)
EP (1) EP1431762B1 (enExample)
JP (1) JP4527544B2 (enExample)
CN (1) CN1726393B (enExample)
AT (1) ATE360817T1 (enExample)
AU (1) AU2003302964A1 (enExample)
CA (1) CA2510150C (enExample)
DE (1) DE60219809T2 (enExample)
ES (1) ES2286201T3 (enExample)
WO (1) WO2004055514A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1431762B1 (en) * 2002-12-18 2007-04-25 Coy, Johannes F., Dr. Compounds and methods for detection of carcinomas and their precursor lesions
US8710012B2 (en) * 2003-07-14 2014-04-29 Cls Therapeutics Limited Method for treating oncological diseases
US8388951B2 (en) 2003-07-14 2013-03-05 Cls Therapeutics Limited Method for treating systemic DNA mutation disease
ES2524458T3 (es) 2006-10-18 2014-12-09 Periness Ltd. DNasa para el tratamiento de la subfertilidad masculina
JP2008253188A (ja) * 2007-04-04 2008-10-23 Tokyo Univ Of Science エンドサイトーシス依存性ｄｎａ取り込み抑制剤、エンドサイトーシス依存性ｄｎａ取り込み促進剤、ウイルス感染阻害剤、ウイルス感染予防剤、及びウイルス感染促進剤、並びに、遺伝子マーカー、モノクローナル抗体、ハイブリドーマ、及びそれらの使用方法。
US7734161B2 (en) * 2007-04-19 2010-06-08 Avago Technologies Ecbu Ip (Singapore) Pte. Ltd. Image stabilization with adaptive shutter control
US9360489B2 (en) * 2007-06-11 2016-06-07 Sutter Bay Hospitals Method and kit for dynamic gene expression monitoring
US10617743B2 (en) 2014-06-19 2020-04-14 Cls Therapeutics Limited Method to improve safety and efficacy of anti-cancer therapy
CN104267011A (zh) * 2014-09-23 2015-01-07 中国科学院东北地理与农业生态研究所 一种转基因羊卵母细胞的筛选方法
ES2799515T3 (es) 2015-05-22 2020-12-18 Dmitry Dmitrievich Genkin ADN extracelular como una diana terapéutica en la neurodegeneración
CN107677822A (zh) * 2016-08-02 2018-02-09 北京金沐医疗科技有限公司 检测肿瘤标志物的荧光细胞计数检测试剂盒
CN107677820A (zh) * 2016-08-02 2018-02-09 北京金沐医疗科技有限公司 一种检测肿瘤抗原的试剂盒及其检测方法
CN107677823A (zh) * 2016-08-02 2018-02-09 北京金沐医疗科技有限公司 一种用于检测肿瘤抗原的蛋白芯片试剂盒及其检测方法
JP2021510539A (ja) 2018-01-16 2021-04-30 シーエルエス セラピューティクス リミテッドＣＬＳ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ デオキシリボヌクレアーゼ（ＤＮａｓｅ）活性を有する酵素の肝臓発現による疾患の処置
CN109406771B (zh) * 2018-10-26 2023-04-07 安徽大千生物工程有限公司 胱抑素c胶乳增强比浊法检测试剂盒及其制备使用方法
WO2020223265A1 (en) * 2019-04-28 2020-11-05 Essenlix Corporation Rapid pathology/cytology without wash
CN113314220B (zh) * 2021-07-28 2021-11-02 江苏为真生物医药技术股份有限公司 疾病病程监控系统、计算机可读存储介质以及电子设备

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19521046C1 (de) * 1995-06-09 1996-08-08 Deutsches Krebsforsch Protein mit DNase-Aktivität
WO2000052204A2 (en) * 1999-02-22 2000-09-08 Orntoft Torben F Gene expression in bladder tumors
US20020052308A1 (en) * 1999-03-12 2002-05-02 Rosen Craig A. Nucleic acids, proteins and antibodies
EP1249495A1 (de) * 2001-04-11 2002-10-16 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Murine DNase X, diese enthaltendes Arzneimittel und nicht-menschliches Säugetier mit verändertem DNase X-Gen
CA2466483A1 (en) * 2001-11-07 2003-07-03 John D. Shaughnessy Diagnosis prognosis and identification of potential therapeutic targets of multiple myeloma based on gene expression profiling
CA2499709A1 (en) * 2002-06-19 2003-12-31 Yoichi Furukawa Method for diagnosis of colorectal tumors
EP1431762B1 (en) * 2002-12-18 2007-04-25 Coy, Johannes F., Dr. Compounds and methods for detection of carcinomas and their precursor lesions

Also Published As

Publication number Publication date
ES2286201T3 (es) 2007-12-01
ATE360817T1 (de) 2007-05-15
AU2003302964A1 (en) 2004-07-09
DE60219809T2 (de) 2008-01-17
CN1726393A (zh) 2006-01-25
EP1431762B1 (en) 2007-04-25
CA2510150C (en) 2017-11-07
EP1431762A1 (en) 2004-06-23
WO2004055514A1 (en) 2004-07-01
US20060121485A1 (en) 2006-06-08
CA2510150A1 (en) 2004-07-01
US8759004B2 (en) 2014-06-24
JP2006510363A (ja) 2006-03-30
DE60219809D1 (de) 2007-06-06
CN1726393B (zh) 2010-04-28
US20080234393A1 (en) 2008-09-25
HK1086331A1 (zh) 2006-09-15

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